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105 Broadway 23,700 - 47,400 SF of 4-Star Office Space Available in Cambridge, MA 02142
Sublease Highlights
- Situated in the epicenter of Cambridge’s innovation district, surrounded by top-tier research institutions and biotech firms
- Currently offering 46,594 RSF across two full floors (2nd and 4th), ideal for lab or office use
- Designed to support life science operations with flexible floor plates and infrastructure suitable for lab conversion
- Home to major tenants including MIT, Thermo Fisher, and the Broad Institute, reflecting the building’s prestige and functionality
- Boston Properties is exploring plans to redevelop the site into a modern lab-and-office tower, signaling long-term value and adaptability
- Excellent connectivity via MBTA Red Line and major roadways, enhancing commuter convenience and regional access.
All Available Spaces(2)
Display Rental Rate as
- Space
- Size
- Term
- Rental Rate
- Space Use
- Build-Out
- Available
- Sublease space available from current tenant
- Mostly Open Floor Plan Layout
- Fully Built-Out as Standard Office
- Fits 60 - 190 People
- Sublease space available from current tenant
- Mostly Open Floor Plan Layout
- Fully Built-Out as Standard Office
- Fits 60 - 190 People
| Space | Size | Term | Rental Rate | Space Use | Build-Out | Available |
| 2nd Floor | 23,700 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office | Full Build-Out | Now |
| 4th Floor | 23,700 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office | Full Build-Out | Now |
2nd Floor
| Size |
| 23,700 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office |
| Build-Out |
| Full Build-Out |
| Available |
| Now |
4th Floor
| Size |
| 23,700 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office |
| Build-Out |
| Full Build-Out |
| Available |
| Now |
2nd Floor
| Size | 23,700 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office |
| Build-Out | Full Build-Out |
| Available | Now |
- Sublease space available from current tenant
- Fully Built-Out as Standard Office
- Mostly Open Floor Plan Layout
- Fits 60 - 190 People
4th Floor
| Size | 23,700 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office |
| Build-Out | Full Build-Out |
| Available | Now |
- Sublease space available from current tenant
- Fully Built-Out as Standard Office
- Mostly Open Floor Plan Layout
- Fits 60 - 190 People
Property Overview
Located in the heart of Kendall Square, 105 Broadway is a premier Class A life science and office building spanning approximately 152,664 square feet across seven stories. Built in 1990, the property has long served as a cornerstone for innovation, housing prominent tenants such as Thermo Fisher Scientific, the Massachusetts Institute of Technology, and the Broad Institute 1. The building offers 46,594 RSF of sublease space, with 23,700 square feet available on both the 2nd and 4th floors 2. Its strategic location places it within one of the most dynamic biotech and research ecosystems in the world, offering unmatched access to talent, transit, and institutional partnerships. The property is currently managed by Boston Properties (BXP), which has proposed redevelopment plans to transform the site into a next-generation lab-and-office tower.
- Bus Line
- Metro/Subway
- Property Manager on Site
- Restaurant
- Security System
- Energy Star Labeled
- Air Conditioning
Property Facts
Select Tenants
- Floor
- Tenant Name
- Industry
- Multiple
- Broad Institute
- Professional, Scientific, and Technical Services
Presented by
105 Broadway
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