1315 N Main St 5,480 SF Retail Building Santa Ana, CA 92701 $3,578,537 CAD ($653.02 CAD/SF)

Prime Investment/Owner-User Opportunity in Santa Ana’s Midtown Corridor
1315 N Main St., Santa Ana, CA 92701
± 5,480 SF building | ± 0.16 AC lot | Asking $2,499,000
Located in the heart of Santa Ana’s emerging Midtown district, this well-positioned commercial asset offers a rare opportunity for investors or owner-users seeking professional, medical or mixed-use flexibility. The property lies within the Midtown Specific Plan (SP3) zoning overlay—giving the buyer access to forward-looking planning regulations designed to encourage dynamic uses, adaptive reuse and walkable, mixed-purpose development.  
Key Highlights
    •    Exceptional frontage along North Main, within close proximity to the Civic Center, Metrolink/Amtrak, major thoroughfares and high-density residential catchment.  
    •    The Midtown Specific Plan (SP3) allows for a wide variety of uses beyond traditional retail or office — including medical/professional services, mixed-use development and adaptive reuse of existing building stock.  
    •    Strong demographics and population growth in the surrounding 1-, 3- and 5-mile radii provide a solid foundation for service-oriented businesses (medical/dental, wellness, professional) to thrive.  
    •    Owner-user or investor friendly: Expand into a dental or medical practice, convert to multi-tenant professional offices, or reposition as a mixed-use asset under SP3’s adaptive reuse mindset.
    •    Streamlined acquisition: This property is listed for sale, providing a rare entry to Santa Ana’s Midtown market.
Strategic Use Case – Medical/Professional Clinic
The SP3 overlay encourages development and reuse that serve the local community and fosters professional and medical amenities in this growing sub-market. For dental or medical practitioners seeking visibility, access, and neighborhood connectivity, this site offers:
    •    A centralized address in a vibrant district with strong pedestrian, transit and vehicular traffic.
    •    A landlord/investor opportunity to market to a quality tenant base — or owner-occupy the facility and benefit from long-term asset value.
    •    A planning framework (SP3) that supports flexible use types — making it easier to conceptualize a dental office, medical practice, wellness campus or professional services hub.
Building & Site Details
    •    Building Size: ± 5,480 SF (per listing)  
    •    Lot Size: ± 0.16 AC / ± 0.16 acres  
    •    Listing Price: $2,499,000 (current as per listing)  
    •    Zoning/Overlay: Midtown Specific Plan (SP3) per City of Santa Ana zoning map legend.  
Why Now
Midtown Santa Ana is undergoing revitalization, driven by transit-oriented planning, infill redevelopment and enhanced service infrastructure. This property aligns perfectly with this trend. By positioning the asset as suitable for medical or professional/clinical use under SP3, you tap into a rising class of demand from healthcare providers seeking urban-core access and yet affordable alternatives to coastal/office-park markets.
Next Steps
Contact us for floor plans, tenant improvement allowance considerations, parking/drive-in access details, and coordination points with the City of Santa Ana Planning Division regarding SP3 permitted/conditional uses (e.g., medical/dental office). With the right tenant or owner-user in place, this property represents both an operational platform and long-term real-estate investment.