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Highlights

  • Turnkey
  • On all major downtown bus routes
  • Strategically located in the center of the healthcare triangle formed by McMaster University, St. Joseph’s Healthcare, and Hamilton General Hospitals
  • Huge Parking Lot

All Available Space(1)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor, Ste 2B
  • 8,171 SF
  • 1-10 Years
  • $24.00 CAD/SF/YR $2.00 CAD/SF/MO $196,104 CAD/YR $16,342 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now

150 Main Street West | Hamilton, Ontario Position your practice at the clinical epicenter of Hamilton. Now available: up to 8,171 SF of fully built-out, turnkey medical office space on the ground floor of 150 Main Street West — strategically located in the center of the healthcare triangle formed by McMaster University, St. Joseph’s Healthcare Hamilton, and Hamilton General Hospital. This is a rare opportunity to step into an operational clinical environment and begin seeing patients immediately. Why This Space Wins: ? Turnkey & Revenue-Ready ? Move in tomorrow. No construction delays. No capital expenditure. ? Flexible Leasing: Lease as little as one 120 SF exam room, or secure up to 8,171 SF for a full-scale operation. ? All-Inclusive Rate: $27.00 per square foot — fully inclusive. Simple, predictable occupancy costs. Clinical Build-Out Includes: ? 8 exam rooms ? Expansive rehabilitation / gym space ? Large Conference room ? Administration office ? Staff kitchen ? Staff washroom ? Staff shower ? Client change rooms ? Client shower ? Loading dock access Designed for efficiency, compliance, and patient flow. Built-In Referral Ecosystem Co-locate within an established, synergistic medical environment including: ? Acute injury & chronic pain care ? Orthopedic surgery ? Family medicine ? Rheumatology ? Allied health services Plus: ? Specialty compounding pharmacy on-site ? Infusion clinic on-site This ecosystem creates immediate cross-referral potential and enhanced patient convenience. Ideal for: ? Diagnostics ? Rehabilitation & physiotherapy ? Private specialist practices ? Phlebotomy & lab services ? Multidisciplinary clinics Accessibility & Visibility ? 290 parking stalls directly across the street ? Prominent exterior signage opportunity on Main Street West ? Ground floor presence for superior accessibility ? Strategic Location Advantage ? On all major downtown bus routes Few properties in Hamilton offer this level of proximity to three major healthcare institutions. This location enhances: ? Specialist referrals ? Hospital adjacency ? Academic affiliation proximity ? Patient accessibility from across the city Opportunity Snapshot: ? Up to 8,171 SF available ? Divisible to single exam rooms ? Fully built-out medical space ? All-inclusive lease structure ? Immediate occupancy Medical spaces of this quality, scale, and location rarely become available. For leasing details, floor plans, or to schedule a confidential tour, contact us today.

  • Rate includes utilities, building services and property expenses
  • Mostly Open Floor Plan Layout
  • 1 Conference Room
  • Space is in Excellent Condition
  • Central Air and Heating
  • Private Restrooms
  • Print/Copy Room
  • Closed Circuit Television Monitoring (CCTV)
  • Freezer Space
  • High Ceilings
  • Secure Storage
  • Natural Light
  • Emergency Lighting
  • Basement
  • DDA Compliant
  • Open-Plan
  • Wheelchair Accessible
  • Located in healthcare triangle.
  • Fully Built-Out as Standard Medical Space
  • 10 Private Offices
  • Finished Ceilings: 10’
  • Reception Area
  • Elevator Access
  • Wi-Fi Connectivity
  • Security System
  • Plug & Play
  • Corner Space
  • Drop Ceilings
  • Recessed Lighting
  • Bicycle Storage
  • Shower Facilities
  • Common Parts WC Facilities
  • Food Service
  • Smoke Detector
  • Premium Turnkey Medical Office Space for Lease
  • Staff kitchen, washroom, and shower.
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor, Ste 2B 8,171 SF 1-10 Years $24.00 CAD/SF/YR $2.00 CAD/SF/MO $196,104 CAD/YR $16,342 CAD/MO Office/Medical Full Build-Out Now

1st Floor, Ste 2B

Size
8,171 SF
Term
1-10 Years
Rental Rate
$24.00 CAD/SF/YR $2.00 CAD/SF/MO $196,104 CAD/YR $16,342 CAD/MO
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

1st Floor, Ste 2B

Size 8,171 SF
Term 1-10 Years
Rental Rate $24.00 CAD/SF/YR
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

150 Main Street West | Hamilton, Ontario Position your practice at the clinical epicenter of Hamilton. Now available: up to 8,171 SF of fully built-out, turnkey medical office space on the ground floor of 150 Main Street West — strategically located in the center of the healthcare triangle formed by McMaster University, St. Joseph’s Healthcare Hamilton, and Hamilton General Hospital. This is a rare opportunity to step into an operational clinical environment and begin seeing patients immediately. Why This Space Wins: ? Turnkey & Revenue-Ready ? Move in tomorrow. No construction delays. No capital expenditure. ? Flexible Leasing: Lease as little as one 120 SF exam room, or secure up to 8,171 SF for a full-scale operation. ? All-Inclusive Rate: $27.00 per square foot — fully inclusive. Simple, predictable occupancy costs. Clinical Build-Out Includes: ? 8 exam rooms ? Expansive rehabilitation / gym space ? Large Conference room ? Administration office ? Staff kitchen ? Staff washroom ? Staff shower ? Client change rooms ? Client shower ? Loading dock access Designed for efficiency, compliance, and patient flow. Built-In Referral Ecosystem Co-locate within an established, synergistic medical environment including: ? Acute injury & chronic pain care ? Orthopedic surgery ? Family medicine ? Rheumatology ? Allied health services Plus: ? Specialty compounding pharmacy on-site ? Infusion clinic on-site This ecosystem creates immediate cross-referral potential and enhanced patient convenience. Ideal for: ? Diagnostics ? Rehabilitation & physiotherapy ? Private specialist practices ? Phlebotomy & lab services ? Multidisciplinary clinics Accessibility & Visibility ? 290 parking stalls directly across the street ? Prominent exterior signage opportunity on Main Street West ? Ground floor presence for superior accessibility ? Strategic Location Advantage ? On all major downtown bus routes Few properties in Hamilton offer this level of proximity to three major healthcare institutions. This location enhances: ? Specialist referrals ? Hospital adjacency ? Academic affiliation proximity ? Patient accessibility from across the city Opportunity Snapshot: ? Up to 8,171 SF available ? Divisible to single exam rooms ? Fully built-out medical space ? All-inclusive lease structure ? Immediate occupancy Medical spaces of this quality, scale, and location rarely become available. For leasing details, floor plans, or to schedule a confidential tour, contact us today.

  • Rate includes utilities, building services and property expenses
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • 10 Private Offices
  • 1 Conference Room
  • Finished Ceilings: 10’
  • Space is in Excellent Condition
  • Reception Area
  • Central Air and Heating
  • Elevator Access
  • Private Restrooms
  • Wi-Fi Connectivity
  • Print/Copy Room
  • Security System
  • Closed Circuit Television Monitoring (CCTV)
  • Plug & Play
  • Freezer Space
  • Corner Space
  • High Ceilings
  • Drop Ceilings
  • Secure Storage
  • Recessed Lighting
  • Natural Light
  • Bicycle Storage
  • Emergency Lighting
  • Shower Facilities
  • Basement
  • Common Parts WC Facilities
  • DDA Compliant
  • Food Service
  • Open-Plan
  • Smoke Detector
  • Wheelchair Accessible
  • Premium Turnkey Medical Office Space for Lease
  • Located in healthcare triangle.
  • Staff kitchen, washroom, and shower.

About the Property

Premium Turnkey Medical Office Space for Lease 150 Main Street West | Hamilton, Ontario Position your practice at the clinical epicenter of Hamilton. Now available: up to 8,171 SF of fully built-out, turnkey medical office space on the ground floor of 150 Main Street West — strategically located in the center of the healthcare triangle formed by McMaster University, St. Joseph’s Healthcare Hamilton, and Hamilton General Hospital. This is a rare opportunity to step into an operational clinical environment and begin seeing patients immediately. Why This Space Wins: ? Turnkey & Revenue-Ready ? Move in tomorrow. No construction delays. No capital expenditure. ? Flexible Leasing: Lease as little as one 120 SF exam room, or secure up to 8,171 SF for a full-scale operation. ? All-Inclusive Rate: $27.00 per square foot — fully inclusive. Simple, predictable occupancy costs. Clinical Build-Out Includes: ? 8 exam rooms ? Expansive rehabilitation / gym space ? Large Conference room ? Administration office ? Staff kitchen ? Staff washroom ? Staff shower ? Client change rooms ? Client shower ? Loading dock access Designed for efficiency, compliance, and patient flow. Built-In Referral Ecosystem Co-locate within an established, synergistic medical environment including: ? Acute injury & chronic pain care ? Orthopedic surgery ? Family medicine ? Rheumatology ? Allied health services Plus: ? Specialty compounding pharmacy on-site ? Infusion clinic on-site This ecosystem creates immediate cross-referral potential and enhanced patient convenience. Ideal for: ? Diagnostics ? Rehabilitation & physiotherapy ? Private specialist practices ? Phlebotomy & lab services ? Multidisciplinary clinics Accessibility & Visibility ? 290 parking stalls directly across the street ? Prominent exterior signage opportunity on Main Street West ? Ground floor presence for superior accessibility ? Strategic Location Advantage ? On all major downtown bus routes Few properties in Hamilton offer this level of proximity to three major healthcare institutions. This location enhances: ? Specialist referrals ? Hospital adjacency ? Academic affiliation proximity ? Patient accessibility from across the city Opportunity Snapshot: ? Up to 8,171 SF available ? Divisible to single exam rooms ? Fully built-out medical space ? All-inclusive lease structure ? Immediate occupancy Medical spaces of this quality, scale, and location rarely become available. For leasing details, floor plans, or to schedule a confidential tour, contact us today.

Property Facts

Total Space Available 8,171 SF
No. Units 150
Property Type Multifamily
Property Subtype Apartment
Apartment Style Hi-Rise
Building Size 125,000 SF
Year Built/Renovated 2016/2023
Exceptionally walkable
100/100
Moderately drivable
70/100
Exceptional public transit
100/100
Moderately bikeable
70/100
  • Listing ID: 39444269

  • Date on Market: 2026-02-14

  • Last Updated:

  • Address: 150 Main St W, Hamilton, ON L8P 1C8

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