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Highlights

  • Heavy Traffic
  • located in the middle of San Mateo Ave

All Available Spaces(3)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Condition
  • Available
  • 1st Floor, Ste 1
  • 1,441 SF
  • 1-2 Years
  • $48.07 CAD/SF/YR $4.01 CAD/SF/MO $69,263 CAD/YR $5,772 CAD/MO
  • Medical
  • Full Build-Out
  • Now

1,441 SF medical/office suite, previously operated as an aesthetic clinic, featuring a functional layout ideal for medical, dental, wellness, or professional use. The suite includes six operatories with sinks, three spacious private offices without sinks, a reception area, a waiting room, and a storage closet. The space is designed to accommodate a mix of treatment and administrative functions efficiently, with flexible room configurations and practical flow for staff and clients. Located in a professional office/medical building on North San Mateo Drive, the suite benefits from strong visibility, foot traffic, and proximity to downtown San Mateo amenities and transit.

  • Fully Built-Out as Standard Medical Space
  • Reception Area
  • Private Restrooms
  • Smoke Detector
  • Office intensive layout
  • Central Air and Heating
  • After Hours HVAC Available
  • 1st Floor, Ste 3
  • 1,020 SF
  • 1-2 Years
  • $48.07 CAD/SF/YR $4.01 CAD/SF/MO $49,027 CAD/YR $4,086 CAD/MO
  • Office/Medical
  • -
  • Now

±1,020 SF office suite featuring a functional layout suitable for medical or general office use. Space offers multiple private offices, reception/waiting area, private restroom, kitchenette with refrigerator and microwave and flexible configuration options. Located within a well-maintained professional building with an established tenant mix. Ideal for therapy, medical, or administrative users seeking an affordable, centrally located space.

  • 4 Private Offices
  • Central Air and Heating
  • Fully Carpeted
  • Smoke Detector
  • Reception Area
  • Private Restrooms
  • Shower Facilities
  • First floor
  • 2nd Floor, Ste 9
  • 715 SF
  • 1-2 Years
  • $49.72 CAD/SF/YR $4.14 CAD/SF/MO $35,552 CAD/YR $2,963 CAD/MO
  • Office/Medical
  • -
  • Now

Unit 9/10 offers a well-configured office/medical suite with a functional layout suited for a variety of professional uses. The space includes waiting area, private offices one of which has a sink, private restroom, storage closets and flexible workspace options. Located within a quiet, well-maintained professional building with an established tenant mix, this suite is ideal for medical, therapy, or administrative users seeking an efficient and affordable space. This unit can be split into 2 separate units and has two different entrances.

  • 3 Private Offices
  • Natural Light
  • Smoke Detector
  • Central Air and Heating
  • After Hours HVAC Available
  • Lots of natural light located on the second floor
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 1 1,441 SF 1-2 Years $48.07 CAD/SF/YR $4.01 CAD/SF/MO $69,263 CAD/YR $5,772 CAD/MO Medical Full Build-Out Now
1st Floor, Ste 3 1,020 SF 1-2 Years $48.07 CAD/SF/YR $4.01 CAD/SF/MO $49,027 CAD/YR $4,086 CAD/MO Office/Medical - Now
2nd Floor, Ste 9 715 SF 1-2 Years $49.72 CAD/SF/YR $4.14 CAD/SF/MO $35,552 CAD/YR $2,963 CAD/MO Office/Medical - Now

1st Floor, Ste 1

Size
1,441 SF
Term
1-2 Years
Rental Rate
$48.07 CAD/SF/YR $4.01 CAD/SF/MO $69,263 CAD/YR $5,772 CAD/MO
Space Use
Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 3

Size
1,020 SF
Term
1-2 Years
Rental Rate
$48.07 CAD/SF/YR $4.01 CAD/SF/MO $49,027 CAD/YR $4,086 CAD/MO
Space Use
Office/Medical
Condition
-
Available
Now

2nd Floor, Ste 9

Size
715 SF
Term
1-2 Years
Rental Rate
$49.72 CAD/SF/YR $4.14 CAD/SF/MO $35,552 CAD/YR $2,963 CAD/MO
Space Use
Office/Medical
Condition
-
Available
Now

1st Floor, Ste 1

Size 1,441 SF
Term 1-2 Years
Rental Rate $48.07 CAD/SF/YR
Space Use Medical
Condition Full Build-Out
Available Now

1,441 SF medical/office suite, previously operated as an aesthetic clinic, featuring a functional layout ideal for medical, dental, wellness, or professional use. The suite includes six operatories with sinks, three spacious private offices without sinks, a reception area, a waiting room, and a storage closet. The space is designed to accommodate a mix of treatment and administrative functions efficiently, with flexible room configurations and practical flow for staff and clients. Located in a professional office/medical building on North San Mateo Drive, the suite benefits from strong visibility, foot traffic, and proximity to downtown San Mateo amenities and transit.

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Reception Area
  • Central Air and Heating
  • Private Restrooms
  • After Hours HVAC Available
  • Smoke Detector

1st Floor, Ste 3

Size 1,020 SF
Term 1-2 Years
Rental Rate $48.07 CAD/SF/YR
Space Use Office/Medical
Condition -
Available Now

±1,020 SF office suite featuring a functional layout suitable for medical or general office use. Space offers multiple private offices, reception/waiting area, private restroom, kitchenette with refrigerator and microwave and flexible configuration options. Located within a well-maintained professional building with an established tenant mix. Ideal for therapy, medical, or administrative users seeking an affordable, centrally located space.

  • 4 Private Offices
  • Reception Area
  • Central Air and Heating
  • Private Restrooms
  • Fully Carpeted
  • Shower Facilities
  • Smoke Detector
  • First floor

2nd Floor, Ste 9

Size 715 SF
Term 1-2 Years
Rental Rate $49.72 CAD/SF/YR
Space Use Office/Medical
Condition -
Available Now

Unit 9/10 offers a well-configured office/medical suite with a functional layout suited for a variety of professional uses. The space includes waiting area, private offices one of which has a sink, private restroom, storage closets and flexible workspace options. Located within a quiet, well-maintained professional building with an established tenant mix, this suite is ideal for medical, therapy, or administrative users seeking an efficient and affordable space. This unit can be split into 2 separate units and has two different entrances.

  • 3 Private Offices
  • Central Air and Heating
  • Natural Light
  • After Hours HVAC Available
  • Smoke Detector
  • Lots of natural light located on the second floor

Property Overview

215 N. San Mateo Drive is a well-maintained professional office and medical building located in the heart of San Mateo. Situated directly on North San Mateo Drive, a well-known corridor lined with medical and professional office buildings, the property benefits from strong visibility and consistent foot traffic. The building features a stable mix of established medical and professional tenants, creating a quiet and professional environment ideal for a variety of users. Its prime location offers excellent walkability, just steps from downtown San Mateo’s restaurants, retail, and services, as well as convenient access to Caltrain. With competitive rental rates and flexible suite configurations, 215 N. San Mateo Drive presents an outstanding opportunity for businesses seeking an affordable presence in a highly desirable and active Peninsula location.

  • 24 Hour Access
  • Property Manager on Site
  • Air Conditioning

Property Facts

Building Type
Office
Year Built
1967
Building Height
2 Stories
Building Size
5,793 SF
Building Class
B
Typical Floor Size
2,897 SF
Parking
15 Surface Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 1st
  • Becker Gregory Dc
  • Health Care and Social Assistance
  • Unknown
  • Christine Moberg, Ph.d
  • Public Administration
  • Unknown
  • Deborah Diaz Lcsw
  • Health Care and Social Assistance
  • 1st
  • Dr June Martin, Marriage & Family Therapist, Inc
  • Health Care and Social Assistance
  • 1st
  • Steven Tulkin Phd
  • Health Care and Social Assistance
  • 1st
  • Three Lotus Dragon Acupuncture Wellness Center
  • Health Care and Social Assistance
  • 1st
  • Youthful Resolutions
  • Arts, Entertainment, and Recreation
Moderately walkable
70/100
Very drivable
80/100
Some public transit
50/100
Fairly bikeable
50/100
  • Listing ID: 39812308

  • Date on Market: 2026-03-17

  • Last Updated:

  • Address: 215 N San Mateo Dr, San Mateo, CA 94401

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