Share This Listing

Message

954 characters remaining

Hmm, there seems to have been an error sending your message. Please try again.

Your email has been sent.

22 S Main St
Greenville, SC 29601
22 S Main · Retail Property For Lease · 8,500 SF

Highlights

  • Prime Main Street location in the center of Downtown Greenville’s retail and dining district
  • Surrounded by top-tier retailers and restaurants, including Anthropologie, Tupelo Honey, and Mast General Store
  • Excellent traffic counts with over 7,200 vehicles per day on Main Street
  • New façade renovation planned to enhance visibility and modernize the storefront
  • Strong demographics with high household incomes and significant visitor spending in the area

Property Facts

Building Type
Office
Year Built/Renovated
2011/2013
Building Height
4 Stories
Building Size
41,494 SF
Building Class
B
Typical Floor Size
10,900 SF
Unfinished Ceiling Height
13’7”
Parking
3 Surface Parking Spaces
Covered Parking

Property Overview

Position your business in the heart of Downtown Greenville with this exceptional retail opportunity at 22 S. Main Street. Offering approximately 8,500 SF of prime ground-floor space, this property is ideally situated along Greenville’s most vibrant retail corridor, directly across from the Wells Fargo Tower. A new façade renovation is underway, ensuring a modern and inviting storefront that will enhance visibility and curb appeal for future tenants. The property benefits from heavy pedestrian and vehicular traffic, with Main Street seeing over 7,200 vehicles per day and McBee Avenue over 7,000 VPD. Surrounded by a dynamic mix of national and local retailers, popular restaurants, and entertainment venues, this location offers unmatched exposure and synergy. Nearby establishments include Methodical Coffee, Anthropologie, Tupelo Honey, Cantina 76, and Mast General Store, creating a strong co-tenancy environment. Downtown Greenville is a thriving destination for residents, visitors, and businesses, with a growing population and robust household incomes averaging over $140,000 within a one-mile radius. The area attracts significant visitor spending, with $793 million allocated to attractions, retail, and entertainment annually. This property is perfectly positioned to capture that demand, making it an ideal choice for flagship retail, experiential concepts, or destination dining.

  • Listing ID: 39354574

  • Date on Market: 2026-02-06

  • Last Updated:

  • Address: 22 S Main St, Greenville, SC 29601

Link copied
Your LoopNet account has been created!

Please Share Your Feedback

We welcome any feedback on how we can improve LoopNet to better serve your needs.
X
{{ getErrorText(feedbackForm.starRating, "rating") }}
255 character limit ({{ remainingChars() }} charactercharacters remainingover)
{{ getErrorText(feedbackForm.msg, "rating") }}
{{ getErrorText(feedbackForm.fname, "first name") }}
{{ getErrorText(feedbackForm.lname, "last name") }}
{{ getErrorText(feedbackForm.phone, "phone number") }}
{{ getErrorText(feedbackForm.phonex, "phone extension") }}
{{ getErrorText(feedbackForm.email, "email address") }}