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Spruce & Myrtle South San Francisco, CA 94080 1,668 - 5,522 SF of Office Space Available

Office Spaces California South San Francisco Spruce & Myrtle

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PARK HIGHLIGHTS

  • Building signage.
  • Close to local amenities and downtown South San Francisco.
  • Within 5 minutes to the San Francisco International Airport.
  • Close to local amenities and downtown South San Francisco.
  • Within 5 minutes to the San Francisco International Airport.
  • Easy access to HWY 101 and 380 & 280.
  • Less than 1 mile to San Bruno Caltrain & BART Stations.
  • Newly renovated with ample parking.
  • Less than 1 mile to San Bruno Caltrain & BART Stations.
  • Easy access to US 101, I-280 & I-380.

PARK FACTS

Total Space Available 5,522 SF Park Type Office Park
Total Space Available 5,522 SF
Park Type Office Park

ALL AVAILABLE SPACES(3)

Display Rental Rate as

Spruce & Myrtle
220 S Spruce Ave
1,668 - 3,828 SF | $37.69 CAD/SF/YR $3.14 CAD/SF/MO $405.69 CAD/m²/YR $33.81 CAD/m²/MO $5,239 - $12,023 CAD/MO $62,867 - $144,277 CAD/YR | View Building Details
Building Type/Class
Office/B
Year Built
1985
Building Size
20,000 SF
Building Height
2 Stories
Typical Floor Size
10,000 SF
Parking
40 Spaces
  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor, Ste 107
  • 1,668 SF
  • Negotiable
  • $37.69 CAD/SF/YR $3.14 CAD/SF/MO $62,867 CAD/YR $5,239 CAD/MO
  • Office
  • Full Build-Out
  • Now

Suite 107 | ±1,668 SF 3 private offices with bullpen.

  • Rate includes utilities, building services and property expenses
  • Mostly Open Floor Plan Layout
  • 3 Private Offices
  • Highway Access: 101, 280, 380
  • Fully Built-Out as Standard Office
  • Fits 5 - 14 People
  • 3 private offices with bullpen.
  • Public Transportation: Bart and CalTrain
  • 2nd Floor, Ste 204
  • 2,160 SF
  • Negotiable
  • $37.69 CAD/SF/YR $3.14 CAD/SF/MO $81,410 CAD/YR $6,784 CAD/MO
  • Office
  • Partial Build-Out
  • Now

Suite 204 | ±2,160 SF Open floor plan

  • Rate includes utilities, building services and property expenses
  • Open Floor Plan Layout
  • Open floor plan
  • Public Transportation: Bart and CalTrain
  • Partially Built-Out as Standard Office
  • Fits 6 - 18 People
  • Highway Access: 101, 280, 380
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 107 1,668 SF Negotiable $37.69 CAD/SF/YR $3.14 CAD/SF/MO $62,867 CAD/YR $5,239 CAD/MO Office Full Build-Out Now
2nd Floor, Ste 204 2,160 SF Negotiable $37.69 CAD/SF/YR $3.14 CAD/SF/MO $81,410 CAD/YR $6,784 CAD/MO Office Partial Build-Out Now
Spruce & Myrtle
220 S Spruce Ave
1,668 - 3,828 SF | $37.69 CAD/SF/YR $3.14 CAD/SF/MO $405.69 CAD/m²/YR $33.81 CAD/m²/MO $5,239 - $12,023 CAD/MO $62,867 - $144,277 CAD/YR | View Building Details
Building Type/Class
Office/B
Year Built
1985
Building Size
20,000 SF
Building Height
2 Stories
Typical Floor Size
10,000 SF
Parking
40 Spaces

220 S Spruce Ave - 1st Floor - Ste 107

Size
1,668 SF
Term
Negotiable
Rental Rate
$37.69 CAD/SF/YR $3.14 CAD/SF/MO $62,867 CAD/YR $5,239 CAD/MO
Space Use
Office
Condition
Full Build-Out
Available
Now

220 S Spruce Ave - 2nd Floor - Ste 204

Size
2,160 SF
Term
Negotiable
Rental Rate
$37.69 CAD/SF/YR $3.14 CAD/SF/MO $81,410 CAD/YR $6,784 CAD/MO
Space Use
Office
Condition
Partial Build-Out
Available
Now
Spruce & Myrtle
510 Myrtle Ave
1,694 SF | $37.69 CAD/SF/YR $3.14 CAD/SF/MO $405.69 CAD/m²/YR $33.81 CAD/m²/MO $5,321 CAD/MO $63,847 CAD/YR | View Building Details
Building Type/Class
Office/B
Year Built
1986
Building Size
20,651 SF
Building Height
2 Stories
Typical Floor Size
10,325 SF
Parking
45 Spaces
  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 2nd Floor, Ste 209
  • 1,694 SF
  • Negotiable
  • $37.69 CAD/SF/YR $3.14 CAD/SF/MO $63,847 CAD/YR $5,321 CAD/MO
  • Office
  • Full Build-Out
  • Now

510 Myrtle Avenue Suite 209 – ±1,694 SF

  • Rate includes utilities, building services and property expenses
  • Fits 5 - 14 People
  • 1 Conference Room
  • Miles To Airport: 5 min to SFO
  • Fully Built-Out as Standard Office
  • 4 Private Offices
  • Highway Access: 101, 280, 380
  • Less than 1 mile to CalTrain: San B
Space Size Term Rental Rate Space Use Condition Available
2nd Floor, Ste 209 1,694 SF Negotiable $37.69 CAD/SF/YR $3.14 CAD/SF/MO $63,847 CAD/YR $5,321 CAD/MO Office Full Build-Out Now
Spruce & Myrtle
510 Myrtle Ave
1,694 SF | $37.69 CAD/SF/YR $3.14 CAD/SF/MO $405.69 CAD/m²/YR $33.81 CAD/m²/MO $5,321 CAD/MO $63,847 CAD/YR | View Building Details
Building Type/Class
Office/B
Year Built
1986
Building Size
20,651 SF
Building Height
2 Stories
Typical Floor Size
10,325 SF
Parking
45 Spaces

510 Myrtle Ave - 2nd Floor - Ste 209

Size
1,694 SF
Term
Negotiable
Rental Rate
$37.69 CAD/SF/YR $3.14 CAD/SF/MO $63,847 CAD/YR $5,321 CAD/MO
Space Use
Office
Condition
Full Build-Out
Available
Now

220 S Spruce Ave - 1st Floor - Ste 107

Size 1,668 SF
Term Negotiable
Rental Rate $37.69 CAD/SF/YR
Space Use Office
Condition Full Build-Out
Available Now

Suite 107 | ±1,668 SF 3 private offices with bullpen.

  • Rate includes utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 5 - 14 People
  • 3 Private Offices
  • 3 private offices with bullpen.
  • Highway Access: 101, 280, 380
  • Public Transportation: Bart and CalTrain

220 S Spruce Ave - 2nd Floor - Ste 204

Size 2,160 SF
Term Negotiable
Rental Rate $37.69 CAD/SF/YR
Space Use Office
Condition Partial Build-Out
Available Now

Suite 204 | ±2,160 SF Open floor plan

  • Rate includes utilities, building services and property expenses
  • Partially Built-Out as Standard Office
  • Open Floor Plan Layout
  • Fits 6 - 18 People
  • Open floor plan
  • Highway Access: 101, 280, 380
  • Public Transportation: Bart and CalTrain

510 Myrtle Ave - 2nd Floor - Ste 209

Size 1,694 SF
Term Negotiable
Rental Rate $37.69 CAD/SF/YR
Space Use Office
Condition Full Build-Out
Available Now

510 Myrtle Avenue Suite 209 – ±1,694 SF

  • Rate includes utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Fits 5 - 14 People
  • 4 Private Offices
  • 1 Conference Room
  • Highway Access: 101, 280, 380
  • Miles To Airport: 5 min to SFO
  • Less than 1 mile to CalTrain: San B

SELECT TENANTS AT THIS PROPERTY

  • FLOOR
  • TENANT NAME
  • INDUSTRY
  • Unknown
  • Aar Corp
  • Construction
  • 2nd
  • Accupulse
  • Services
  • 2nd
  • Bahour & Patrick CPAS PC
  • Professional, Scientific, and Technical Services
  • 1st
  • Bay Alarm Company
  • Services
  • 1st
  • Carpet Cleaning South San Francisco
  • Services
  • 2nd
  • Enable Bioscience
  • Manufacturing
  • Unknown
  • Lockout Center
  • Services
  • Unknown
  • Omar Hamdi Azghoul
  • -
  • 1st
  • Unimed International
  • Health Care and Social Assistance
  • Unknown
  • Western Overseas
  • Retailer

PARK OVERVIEW

510 Myrtle and 220 S Spruce are two buildings on one parcel.

ATTACHMENTS

220 S. Spruce Ave & 510 Myrtle Ave 9.25.25
1 1
Walk Score®
Very Walkable (78)
Bike Score®
Very Bikeable (86)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures the walkability of any address.
Transit Score® measures access to public transit.
Bike Score® measures bikeability of a location.
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures the walkability
of any address. Transit Score®
measures access to public transit. Bike Score®
measures bikeability of a location.®
Learn How It Works Detailed Scores
(415) 505-0237

Still interested?

Contact the broker for more information about this property

CONTACT

  • Listing ID: 37739832

  • Date on Market: 2025-09-19

  • Last Updated:

  • Address: 220 S Spruce Ave, South San Francisco, CA 94080

The Orange Park Office Property at 220 S Spruce Ave, South San Francisco, CA 94080 is currently available. Contact Colliers for more information.

PROPERTIES IN NEARBY NEIGHBORHOODS

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220 S Spruce Ave, South San Francisco, CA for lease Building Photo- Image 1 of 6
Building Exterior Right Angle
220 S Spruce Ave, South San Francisco, CA for lease Building Photo- Image 2 of 6
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Entrance
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Spruce & Myrtle | South San Francisco, CA 94080
(415) 505-0237 x

Spruce & Myrtle | South San Francisco, CA 94080

Mike Davis
(415) 505-0237

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