224 S Main St
Edwardsville, IL 62025
1,736 SF Professional Office Building · Office Property For Lease · 1,565 SF

Located along the highly sought-after South Main Street corridor, 224 S. Main Street offers the opportunity to own a 1,736 SF professional office building in one of the Metro East’s most desirable commercial submarkets. The property features a functional office layout, excellent accessibility, and dedicated off-street parking—a rare and valuable amenity in this corridor. Surrounded by established businesses, restaurants, and residential neighborhoods, the property is well-suited for an owner-user or investor seeking a quality office asset in the heart of Edwardsville. Situated in the heart of Edwardsville, 224 S. Main Street enjoys a premier location along one of the city’s most established commercial corridors. The property is surrounded by a strong mix of professional offices, medical users, restaurants, retail, and upscale residential neighborhoods, offering exceptional convenience for both employees and clients. Its central location provides quick access to Downtown Edwardsville, Southern Illinois University Edwardsville (SIUE), Illinois Route 157, and Interstate 270, making it an ideal setting for a variety of professional office users. Edwardsville continues to be one of the fastest-growing and most desirable communities in the St. Louis Metro East, supported by a strong local economy, a highly educated workforce, and an excellent quality of life.