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Los Portales Medical Center 2480 Mission St 445 - 13,576 SF of Office/Medical Space Available in San Francisco, CA 94110

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HIGHLIGHTS

  • Premier Medical building located in the mission district. Many of suites are equipped with plubming for dental chairs.
  • Onsite parking available
  • Excellent public transportation - Muni and BART (24th & Mission)
  • Elevator served

ALL AVAILABLE SPACES(13)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor, Ste 104
  • 975 SF
  • Negotiable
  • $41.48 CAD/SF/YR $3.46 CAD/SF/MO $40,438 CAD/YR $3,370 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now

Office/Medical Space

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Office
  • Finished Ceilings: 8’
  • 1st Floor, Ste 106
  • 992 SF
  • Negotiable
  • $62.21 CAD/SF/YR $5.18 CAD/SF/MO $61,715 CAD/YR $5,143 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Office
  • Finished Ceilings: 8’
  • 1st Floor, Ste 107 A
  • 727 SF
  • Negotiable
  • $41.48 CAD/SF/YR $3.46 CAD/SF/MO $30,152 CAD/YR $2,513 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Office
  • Finished Ceilings: 8’
  • 1st Floor, Ste 107 B
  • 445 SF
  • Negotiable
  • $41.48 CAD/SF/YR $3.46 CAD/SF/MO $18,456 CAD/YR $1,538 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Office
  • Finished Ceilings: 8’
  • 1st Floor, Ste 109
  • 1,054 SF
  • Negotiable
  • $41.48 CAD/SF/YR $3.46 CAD/SF/MO $43,715 CAD/YR $3,643 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Office
  • Finished Ceilings: 8’
  • 1st Floor, Ste 110
  • 568 SF
  • Negotiable
  • $45.62 CAD/SF/YR $3.80 CAD/SF/MO $25,914 CAD/YR $2,159 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Office
  • Finished Ceilings: 8’
  • 2nd Floor, Ste 214
  • 1,109 SF
  • Negotiable
  • $62.21 CAD/SF/YR $5.18 CAD/SF/MO $68,994 CAD/YR $5,749 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now

1,109 square foot office/medical space along with a mix of private offices available. Complete Dental chair plumbing in place.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’
  • Wheelchair Accessible
  • Fully Built-Out as Standard Medical Space
  • 2 Private Offices
  • Private Restrooms
  • 2nd Floor, Ste 216
  • 1,129 SF
  • Negotiable
  • $45.62 CAD/SF/YR $3.80 CAD/SF/MO $51,508 CAD/YR $4,292 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now

1,129 square foot office/medical space along with a mix of private offices available.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’
  • Private Restrooms
  • Fully Built-Out as Standard Medical Space
  • 2 Private Offices
  • Space is in Excellent Condition
  • 2nd Floor, Ste 217
  • 1,009 SF
  • Negotiable
  • $45.62 CAD/SF/YR $3.80 CAD/SF/MO $46,033 CAD/YR $3,836 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now

1,009 square foot office/medical space along with a mix of private offices available.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’
  • Private Restrooms
  • Fully Built-Out as Dental Office Space
  • 3 Private Offices
  • Space is in Excellent Condition
  • Wheelchair Accessible
  • 2nd Floor, Ste 218-219
  • 2,548 SF
  • Negotiable
  • $62.21 CAD/SF/YR $5.18 CAD/SF/MO $158,517 CAD/YR $13,210 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now

2,548 square foot office/medical space along with a mix of private offices available. Complete Dental chair plumbing in place.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’
  • Private Restrooms
  • Fully Built-Out as Dental Office Space
  • 4 Private Offices
  • Space is in Excellent Condition
  • Wheelchair Accessible
  • 2nd Floor, Ste 220
  • 1,176 SF
  • Negotiable
  • $45.62 CAD/SF/YR $3.80 CAD/SF/MO $53,652 CAD/YR $4,471 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now

1,176 square foot office/medical space along with a mix of private offices available. Complete Dental chair plumbing in place.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’
  • Private Restrooms
  • Fully Built-Out as Dental Office Space
  • 3 Private Offices
  • Space is in Excellent Condition
  • 2nd Floor, Ste 221
  • 918 SF
  • Negotiable
  • $45.62 CAD/SF/YR $3.80 CAD/SF/MO $41,881 CAD/YR $3,490 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now

918 square foot office/medical space along with a mix of private offices available. Complete Dental chair plumbing in place.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’
  • Private Restrooms
  • Fully Built-Out as Dental Office Space
  • 2 Private Offices
  • Space is in Excellent Condition
  • Wheelchair Accessible
  • 2nd Floor, Ste 222
  • 926 SF
  • Negotiable
  • $45.62 CAD/SF/YR $3.80 CAD/SF/MO $42,246 CAD/YR $3,521 CAD/MO
  • Office/Medical
  • Full Build-Out
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Office
  • Finished Ceilings: 8’
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 104 975 SF Negotiable $41.48 CAD/SF/YR $3.46 CAD/SF/MO $40,438 CAD/YR $3,370 CAD/MO Office/Medical Full Build-Out Now
1st Floor, Ste 106 992 SF Negotiable $62.21 CAD/SF/YR $5.18 CAD/SF/MO $61,715 CAD/YR $5,143 CAD/MO Office/Medical Full Build-Out Now
1st Floor, Ste 107 A 727 SF Negotiable $41.48 CAD/SF/YR $3.46 CAD/SF/MO $30,152 CAD/YR $2,513 CAD/MO Office/Medical Full Build-Out Now
1st Floor, Ste 107 B 445 SF Negotiable $41.48 CAD/SF/YR $3.46 CAD/SF/MO $18,456 CAD/YR $1,538 CAD/MO Office/Medical Full Build-Out Now
1st Floor, Ste 109 1,054 SF Negotiable $41.48 CAD/SF/YR $3.46 CAD/SF/MO $43,715 CAD/YR $3,643 CAD/MO Office/Medical Full Build-Out Now
1st Floor, Ste 110 568 SF Negotiable $45.62 CAD/SF/YR $3.80 CAD/SF/MO $25,914 CAD/YR $2,159 CAD/MO Office/Medical Full Build-Out Now
2nd Floor, Ste 214 1,109 SF Negotiable $62.21 CAD/SF/YR $5.18 CAD/SF/MO $68,994 CAD/YR $5,749 CAD/MO Office/Medical Full Build-Out Now
2nd Floor, Ste 216 1,129 SF Negotiable $45.62 CAD/SF/YR $3.80 CAD/SF/MO $51,508 CAD/YR $4,292 CAD/MO Office/Medical Full Build-Out Now
2nd Floor, Ste 217 1,009 SF Negotiable $45.62 CAD/SF/YR $3.80 CAD/SF/MO $46,033 CAD/YR $3,836 CAD/MO Office/Medical Full Build-Out Now
2nd Floor, Ste 218-219 2,548 SF Negotiable $62.21 CAD/SF/YR $5.18 CAD/SF/MO $158,517 CAD/YR $13,210 CAD/MO Office/Medical Full Build-Out Now
2nd Floor, Ste 220 1,176 SF Negotiable $45.62 CAD/SF/YR $3.80 CAD/SF/MO $53,652 CAD/YR $4,471 CAD/MO Office/Medical Full Build-Out Now
2nd Floor, Ste 221 918 SF Negotiable $45.62 CAD/SF/YR $3.80 CAD/SF/MO $41,881 CAD/YR $3,490 CAD/MO Office/Medical Full Build-Out Now
2nd Floor, Ste 222 926 SF Negotiable $45.62 CAD/SF/YR $3.80 CAD/SF/MO $42,246 CAD/YR $3,521 CAD/MO Office/Medical Full Build-Out Now

1st Floor, Ste 104

Size
975 SF
Term
Negotiable
Rental Rate
$41.48 CAD/SF/YR $3.46 CAD/SF/MO $40,438 CAD/YR $3,370 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 106

Size
992 SF
Term
Negotiable
Rental Rate
$62.21 CAD/SF/YR $5.18 CAD/SF/MO $61,715 CAD/YR $5,143 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 107 A

Size
727 SF
Term
Negotiable
Rental Rate
$41.48 CAD/SF/YR $3.46 CAD/SF/MO $30,152 CAD/YR $2,513 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 107 B

Size
445 SF
Term
Negotiable
Rental Rate
$41.48 CAD/SF/YR $3.46 CAD/SF/MO $18,456 CAD/YR $1,538 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 109

Size
1,054 SF
Term
Negotiable
Rental Rate
$41.48 CAD/SF/YR $3.46 CAD/SF/MO $43,715 CAD/YR $3,643 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 110

Size
568 SF
Term
Negotiable
Rental Rate
$45.62 CAD/SF/YR $3.80 CAD/SF/MO $25,914 CAD/YR $2,159 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 214

Size
1,109 SF
Term
Negotiable
Rental Rate
$62.21 CAD/SF/YR $5.18 CAD/SF/MO $68,994 CAD/YR $5,749 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 216

Size
1,129 SF
Term
Negotiable
Rental Rate
$45.62 CAD/SF/YR $3.80 CAD/SF/MO $51,508 CAD/YR $4,292 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 217

Size
1,009 SF
Term
Negotiable
Rental Rate
$45.62 CAD/SF/YR $3.80 CAD/SF/MO $46,033 CAD/YR $3,836 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 218-219

Size
2,548 SF
Term
Negotiable
Rental Rate
$62.21 CAD/SF/YR $5.18 CAD/SF/MO $158,517 CAD/YR $13,210 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 220

Size
1,176 SF
Term
Negotiable
Rental Rate
$45.62 CAD/SF/YR $3.80 CAD/SF/MO $53,652 CAD/YR $4,471 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 221

Size
918 SF
Term
Negotiable
Rental Rate
$45.62 CAD/SF/YR $3.80 CAD/SF/MO $41,881 CAD/YR $3,490 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 222

Size
926 SF
Term
Negotiable
Rental Rate
$45.62 CAD/SF/YR $3.80 CAD/SF/MO $42,246 CAD/YR $3,521 CAD/MO
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 104

Size 975 SF
Term Negotiable
Rental Rate $41.48 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

Office/Medical Space

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’

1st Floor, Ste 106

Size 992 SF
Term Negotiable
Rental Rate $62.21 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’

1st Floor, Ste 107 A

Size 727 SF
Term Negotiable
Rental Rate $41.48 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’

1st Floor, Ste 107 B

Size 445 SF
Term Negotiable
Rental Rate $41.48 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’

1st Floor, Ste 109

Size 1,054 SF
Term Negotiable
Rental Rate $41.48 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’

1st Floor, Ste 110

Size 568 SF
Term Negotiable
Rental Rate $45.62 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’

2nd Floor, Ste 214

Size 1,109 SF
Term Negotiable
Rental Rate $62.21 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

1,109 square foot office/medical space along with a mix of private offices available. Complete Dental chair plumbing in place.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • 2 Private Offices
  • Finished Ceilings: 8’
  • Private Restrooms
  • Wheelchair Accessible

2nd Floor, Ste 216

Size 1,129 SF
Term Negotiable
Rental Rate $45.62 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

1,129 square foot office/medical space along with a mix of private offices available.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • 2 Private Offices
  • Finished Ceilings: 8’
  • Space is in Excellent Condition
  • Private Restrooms

2nd Floor, Ste 217

Size 1,009 SF
Term Negotiable
Rental Rate $45.62 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

1,009 square foot office/medical space along with a mix of private offices available.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Dental Office Space
  • Mostly Open Floor Plan Layout
  • 3 Private Offices
  • Finished Ceilings: 8’
  • Space is in Excellent Condition
  • Private Restrooms
  • Wheelchair Accessible

2nd Floor, Ste 218-219

Size 2,548 SF
Term Negotiable
Rental Rate $62.21 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

2,548 square foot office/medical space along with a mix of private offices available. Complete Dental chair plumbing in place.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Dental Office Space
  • Mostly Open Floor Plan Layout
  • 4 Private Offices
  • Finished Ceilings: 8’
  • Space is in Excellent Condition
  • Private Restrooms
  • Wheelchair Accessible

2nd Floor, Ste 220

Size 1,176 SF
Term Negotiable
Rental Rate $45.62 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

1,176 square foot office/medical space along with a mix of private offices available. Complete Dental chair plumbing in place.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Dental Office Space
  • Mostly Open Floor Plan Layout
  • 3 Private Offices
  • Finished Ceilings: 8’
  • Space is in Excellent Condition
  • Private Restrooms

2nd Floor, Ste 221

Size 918 SF
Term Negotiable
Rental Rate $45.62 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

918 square foot office/medical space along with a mix of private offices available. Complete Dental chair plumbing in place.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Dental Office Space
  • Mostly Open Floor Plan Layout
  • 2 Private Offices
  • Finished Ceilings: 8’
  • Space is in Excellent Condition
  • Private Restrooms
  • Wheelchair Accessible

2nd Floor, Ste 222

Size 926 SF
Term Negotiable
Rental Rate $45.62 CAD/SF/YR
Space Use Office/Medical
Condition Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Finished Ceilings: 8’

PROPERTY OVERVIEW

Los Portales Medical and Dental Center, 2480 Mission Street. Nestled in San Francisco’s lively Mission District. This property is recognized as one of the neighborhood’s leading destinations for medical services. The building is home to a diverse group of healthcare professionals, including physicians, dentists, optometrists, and other specialized practitioners, making it a hub for patient care and wellness. + Suites ranging from 445 SF to 2,548 SF. Ability to merge some units + Available plumbed up dental office spaces + Well-maintained, professional spaces suitable for a variety of medical and dental practice uses, including a space at street level for a pharmacy, other health care products, or a therapy practice + Flexible Terms + Competitive introductory lease rent + Single occupants or groups are welcome. + Easy Access to BART & MUNI + Ample amenities in the surrounding area + Perfect for medical, professional services, personal services, beauty services, estheticians, dentists, other dental trade users, or a variety of therapists, etc. + Nearby Medical Institutions: Sutter Health’s CPMC Mission Bernal Campus and Zuckerberg San Francisco General Hospital & Trauma Center are both located nearby, fostering a collaborative medical community and providing additional resources for referrals and patient care. + Secure, on-site parking garage with ease of access for tenants + Open Monday-Saturday

  • 24 Hour Access
  • Wheelchair Accessible
  • Roof Terrace

PROPERTY FACTS

Building Type
Office
Year Built/Renovated
1972/2024
Building Height
3 Stories
Building Size
36,969 SF
Building Class
B
Typical Floor Size
12,323 SF
Unfinished Ceiling Height
10’
Parking
Surface Tandem Parking
24 Covered Parking Spaces at $415 CAD/month
Covered Tandem Parking
Reserved Parking
Walk Score®
Walker's Paradise (99)
Transit Score®
Excellent Transit (89)
Bike Score®
Biker's Paradise (99)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures the walkability of any address.
Transit Score® measures access to public transit.
Bike Score® measures bikeability of a location.
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures the walkability
of any address. Transit Score®
measures access to public transit. Bike Score®
measures bikeability of a location.®
  • Listing ID: 36812298

  • Date on Market: 2025-07-18

  • Last Updated:

  • Address: 2480 Mission St, San Francisco, CA 94110

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