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UofL Health - Plaza Two 250 E Liberty St 433 - 39,146 SF of Medical Space Available in Louisville, KY 40202

Medical Offices Kentucky Louisville 250 E Liberty St, Louisville, KY 40202

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ALL AVAILABLE SPACES(12)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 2nd Floor, Ste 200
  • 1,435 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now

The property features free on-site parking in the heart of downtown Louisville. The building borders the Downtown Louisville Medical Corridor, including the affiliated UofL Health Hospitals, Novak Center For Children’s Health, and Norton Hospital and Healthcare Pavilion. The building is proudly managed by the owner. The site has convenient access from Hwy 65/ Dr. Martin Luther King Jr Expressway and is 7 miles from the Louisville International Airport

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Central Air and Heating
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • 3rd Floor, Ste 301
  • 3,435 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • Central Air and Heating
  • 4th Floor, Ste 400
  • 3,311 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • Central Air and Heating
  • 4th Floor, Ste 410
  • 4,119 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • Central Air and Heating
  • 4th Floor, Ste 420
  • 1,770 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • 2026-09-01
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • 6th Floor, Ste 602
  • 4,525 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Central Air and Heating
  • Office intensive layout
  • 7th Floor, Ste 714
  • 3,015 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • Central Air and Heating
  • 9th Floor, Ste 902
  • 3,462 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • Central Air and Heating
  • 9th Floor, Ste 903
  • 433 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • Central Air and Heating
  • 9th Floor, Ste 905
  • 1,184 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • Central Air and Heating
  • 9th Floor, Ste 909
  • 2,586 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • Central Air and Heating
  • 10th Floor, Ste 1001
  • 9,871 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • Central Air and Heating
Space Size Term Rental Rate Space Use Condition Available
2nd Floor, Ste 200 1,435 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
3rd Floor, Ste 301 3,435 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
4th Floor, Ste 400 3,311 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
4th Floor, Ste 410 4,119 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
4th Floor, Ste 420 1,770 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out 2026-09-01
6th Floor, Ste 602 4,525 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
7th Floor, Ste 714 3,015 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
9th Floor, Ste 902 3,462 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
9th Floor, Ste 903 433 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
9th Floor, Ste 905 1,184 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
9th Floor, Ste 909 2,586 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
10th Floor, Ste 1001 9,871 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now

2nd Floor, Ste 200

Size
1,435 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

3rd Floor, Ste 301

Size
3,435 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

4th Floor, Ste 400

Size
3,311 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

4th Floor, Ste 410

Size
4,119 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

4th Floor, Ste 420

Size
1,770 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
2026-09-01

6th Floor, Ste 602

Size
4,525 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

7th Floor, Ste 714

Size
3,015 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

9th Floor, Ste 902

Size
3,462 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

9th Floor, Ste 903

Size
433 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

9th Floor, Ste 905

Size
1,184 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

9th Floor, Ste 909

Size
2,586 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

10th Floor, Ste 1001

Size
9,871 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 200

Size 1,435 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

The property features free on-site parking in the heart of downtown Louisville. The building borders the Downtown Louisville Medical Corridor, including the affiliated UofL Health Hospitals, Novak Center For Children’s Health, and Norton Hospital and Healthcare Pavilion. The building is proudly managed by the owner. The site has convenient access from Hwy 65/ Dr. Martin Luther King Jr Expressway and is 7 miles from the Louisville International Airport

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

3rd Floor, Ste 301

Size 3,435 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

4th Floor, Ste 400

Size 3,311 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

4th Floor, Ste 410

Size 4,119 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

4th Floor, Ste 420

Size 1,770 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available 2026-09-01

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition

6th Floor, Ste 602

Size 4,525 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Central Air and Heating

7th Floor, Ste 714

Size 3,015 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

9th Floor, Ste 902

Size 3,462 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

9th Floor, Ste 903

Size 433 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

9th Floor, Ste 905

Size 1,184 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

9th Floor, Ste 909

Size 2,586 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

10th Floor, Ste 1001

Size 9,871 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
  • Central Air and Heating

PROPERTY OVERVIEW

NTS is pleased to present UofL Health Plaza Two, an exciting leasing opportunity at 250 E Liberty Street. Built in 2008, UofL Health Plaza Two features 10 floors with approximately 102,000 square feet of Class B Outpatient Medical Space. Please see the information below and on the next page for more details: • Prime Location Directly Adjacent to the Downtown Medical Corridor • Outpatient Medical Property • Ample Surface Parking • Easy Access to I-65 • Vending café with seating • Abundant Retail, Restaurants, and Amenities Nearby • Professional Space Planning Provided • See Attached Floor Plans

  • Central Heating
  • Air Conditioning

PROPERTY FACTS

Building Type
Office
Year Built
2008
Building Height
10 Stories
Building Size
102,450 SF
Building Class
B
Typical Floor Size
10,245 SF
Parking
50 Surface Parking Spaces
100 Covered Parking Spaces

ATTACHMENTS

UofL Health Plaza 2 Brochure EV 6.25.24
UofL Health - Plaza 2 - Available Suite Floor Plans (4.1.25)

LINKS

1 1
250 E Liberty St, Louisville, KY - AERIAL map view
Walk Score®
Very Walkable (87)
Bike Score®
Very Bikeable (80)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures the walkability of any address.
Transit Score® measures access to public transit.
Bike Score® measures bikeability of a location.
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures the walkability
of any address. Transit Score®
measures access to public transit. Bike Score®
measures bikeability of a location.®
Learn How It Works Detailed Scores
(502) 429-9820

Still interested?

Contact the brokers for more information about this property

CONTACTS

  • Listing ID: 31724234

  • Date on Market: 2025-09-09

  • Last Updated:

  • Address: 250 E Liberty St, Louisville, KY 40202

The Fourth Street Medical Property at 250 E Liberty St, Louisville, KY 40202 is currently available. Contact NTS for more information.

OFFICE PROPERTIES IN NEARBY NEIGHBORHOODS

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UofL Health - Plaza Two | 250 E Liberty St
(502) 429-9820 x

UofL Health - Plaza Two | 250 E Liberty St

Tony Fluhr
(502) 429-9820

Mark Meredith
(502) 429-9827 x127

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