3520 Fifth Ave
Pittsburgh, PA 15213
Office Property For Sale

Colliers Pittsburgh is pleased to present the opportunity to acquire the fee simple interest in The Keystone Building (the “Property” or “The Keystone Building“). The Class B, 32,763 SF Academia Clinical - Research Facility is located at 3520 Fifth Ave Pittsburgh, PA 15213. The property is in the Oakland neighborhood of Pittsburgh, one of the strongest Education/Research/Medical corridors in the nation. The property is located amongst Carnegie Mellon University, UPMC, and the University of Pittsburgh Oakland Campus flanked by UPMC Presbyterian and UPMC Montefiore. The asset is adjacent to the UPMC Presbyterian Expansion, The Tower. UPMC broke ground on June 14th, 2022, on the largest hospital in Pittsburgh’s history (1.2 million-square-foot) and the largest health care construction project in Pennsylvania. The new $1.5 billion, 17-story UPMC Presbyterian, to be completed in 2026, will be home to 636 private patient rooms and premier people-focused clinical facilities where UPMC clinical teams and physician-scientists will deliver nationally renowned specialty care that includes transplant, cardiology and cardiac surgery, and neurology and neurosurgery. The Keystone Building, located at the heart of Pittsburgh’s thriving commercial sector, is on the verge of witnessing a transformative phase in its vicinity. Adjacent to this iconic structure, a new 10-story life sciences building is currently under construction at 3440 Forbes Avenue. Spearheaded by Baltimore based Wexford Science & Technology, this development is set to enhance the biomedical and technological landscape of the area. Further enhancing the medical facilities near The Keystone Building, UPMC is planning a significant expansion at UPMC Children’s Hospital. This expansion involves a new 50,000-square-foot addition dedicated to a state-of-the-art heart institute, expected to occupy approximately half of the hospital’s existing garage on 45th Street. This addition is poised to further cement the area’s reputation as a hub for medical excellence. Amid these exciting developments, The Keystone Building itself presents a rare opportunity for investors and owner-users. With significant blocks of vacant space soon to become available, this presents a unique chance in one of Pittsburgh’s tightest office submarkets. This combination of nearby high-profile developments and available space makes The Keystone Building a prime location for businesses looking to thrive in a dynamic urban setting.