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Highlights

  • Located at the entrance to Kiawah and Seabrook Islands, 20 minutes from downtown Charleston.
  • Surrounded by affluent communities with projected average household incomes over $190,000 by 2030.
  • Strong year-round demand driven by luxury residential communities, tourism, and second-home owners.
  • ±82,000 SF of retail, dining, and office space available for lease within a 34-acre mixed-use development.
  • High visibility along Betsy Kerrison Parkway with ±20,000 vehicles per day.
  • Close proximity to Freshfields Village, a popular retail and dining destination.

All Available Spaces(2)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Condition
  • Available
  • 1st Floor, Ste 501
  • 2,487 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now

South Island Market offers an exceptional leasing opportunity within a thoughtfully planned mixed-use development on Lower Johns Island, just 20 minutes from downtown Charleston. This ±34-acre project is designed to deliver a curated blend of retail, dining, and office spaces, complemented by 79 luxury townhomes. The development’s architecture and layout reflect the charm of the Lowcountry while providing modern amenities and convenience for tenants and visitors alike. Positioned at the gateway to Kiawah and Seabrook Islands, South Island Market benefits from a robust trade area characterized by high household incomes and steady population growth. The surrounding community includes luxury resorts, golf courses, and pristine beaches, attracting both year-round residents and seasonal visitors. With projected average household incomes exceeding $190,000 and a growing base of affluent consumers, this location offers unparalleled visibility and access to a highly desirable demographic. Tenants will enjoy strong traffic counts along Betsy Kerrison Parkway, ample parking, and proximity to Freshfields Village, a popular retail and dining destination. South Island Market is poised to become a premier lifestyle hub for the region, offering a unique opportunity for retailers, restaurants, and service providers to establish a presence in one of South Carolina’s most sought-after markets.

  • Fully Built-Out as Health Care Space
  • Space is in Excellent Condition
  • 1st Floor, Ste 502
  • 2,487 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now

South Island Market offers an exceptional leasing opportunity within a thoughtfully planned mixed-use development on Lower Johns Island, just 20 minutes from downtown Charleston. This ±34-acre project is designed to deliver a curated blend of retail, dining, and office spaces, complemented by 79 luxury townhomes. The development’s architecture and layout reflect the charm of the Lowcountry while providing modern amenities and convenience for tenants and visitors alike. Positioned at the gateway to Kiawah and Seabrook Islands, South Island Market benefits from a robust trade area characterized by high household incomes and steady population growth. The surrounding community includes luxury resorts, golf courses, and pristine beaches, attracting both year-round residents and seasonal visitors. With projected average household incomes exceeding $190,000 and a growing base of affluent consumers, this location offers unparalleled visibility and access to a highly desirable demographic. Tenants will enjoy strong traffic counts along Betsy Kerrison Parkway, ample parking, and proximity to Freshfields Village, a popular retail and dining destination. South Island Market is poised to become a premier lifestyle hub for the region, offering a unique opportunity for retailers, restaurants, and service providers to establish a presence in one of South Carolina’s most sought-after markets.

  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 501 2,487 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
1st Floor, Ste 502 2,487 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now

1st Floor, Ste 501

Size
2,487 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 502

Size
2,487 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Condition
Full Build-Out
Available
Now

1st Floor, Ste 501

Size 2,487 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

South Island Market offers an exceptional leasing opportunity within a thoughtfully planned mixed-use development on Lower Johns Island, just 20 minutes from downtown Charleston. This ±34-acre project is designed to deliver a curated blend of retail, dining, and office spaces, complemented by 79 luxury townhomes. The development’s architecture and layout reflect the charm of the Lowcountry while providing modern amenities and convenience for tenants and visitors alike. Positioned at the gateway to Kiawah and Seabrook Islands, South Island Market benefits from a robust trade area characterized by high household incomes and steady population growth. The surrounding community includes luxury resorts, golf courses, and pristine beaches, attracting both year-round residents and seasonal visitors. With projected average household incomes exceeding $190,000 and a growing base of affluent consumers, this location offers unparalleled visibility and access to a highly desirable demographic. Tenants will enjoy strong traffic counts along Betsy Kerrison Parkway, ample parking, and proximity to Freshfields Village, a popular retail and dining destination. South Island Market is poised to become a premier lifestyle hub for the region, offering a unique opportunity for retailers, restaurants, and service providers to establish a presence in one of South Carolina’s most sought-after markets.

  • Fully Built-Out as Health Care Space
  • Space is in Excellent Condition

1st Floor, Ste 502

Size 2,487 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Condition Full Build-Out
Available Now

South Island Market offers an exceptional leasing opportunity within a thoughtfully planned mixed-use development on Lower Johns Island, just 20 minutes from downtown Charleston. This ±34-acre project is designed to deliver a curated blend of retail, dining, and office spaces, complemented by 79 luxury townhomes. The development’s architecture and layout reflect the charm of the Lowcountry while providing modern amenities and convenience for tenants and visitors alike. Positioned at the gateway to Kiawah and Seabrook Islands, South Island Market benefits from a robust trade area characterized by high household incomes and steady population growth. The surrounding community includes luxury resorts, golf courses, and pristine beaches, attracting both year-round residents and seasonal visitors. With projected average household incomes exceeding $190,000 and a growing base of affluent consumers, this location offers unparalleled visibility and access to a highly desirable demographic. Tenants will enjoy strong traffic counts along Betsy Kerrison Parkway, ample parking, and proximity to Freshfields Village, a popular retail and dining destination. South Island Market is poised to become a premier lifestyle hub for the region, offering a unique opportunity for retailers, restaurants, and service providers to establish a presence in one of South Carolina’s most sought-after markets.

  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition

About the Property

South Island Market is a planned mixed-use development located at the southeast corner of Betsy Kerrison Parkway and River Road on Johns Island, South Carolina. The project encompasses approximately 34 acres and includes retail, restaurant, office space, and residential townhomes. It is situated near Kiawah and Seabrook Islands and approximately 20 minutes from downtown Charleston. The surrounding area includes residential communities, golf courses, and resort destinations.

Property Facts

Total Space Available 4,974 SF
Property Type Health Care
Building Class B
Building Size 9,944 SF
Year Built 2026
Not walkable
10/100
Exceptionally drivable
100/100
Limited public transit
30/100
Somewhat bikeable
30/100
  • Listing ID: 39921984

  • Date on Market: 2026-03-26

  • Last Updated:

  • Address: 3791 Betsy Kerrison Pky, Johns Island, SC 29455

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