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Kilroy Oyster Point South San Francisco, CA 94080 16,236 - 454,736 SF of Flex Space Available

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Park Highlights

  • 3 buildings (7-8 stories) totaling 865,000 SF
  • Purpose-built lab and office design with large open floor plates and high-capacity infrastructure.
  • Immediate access to beaches, trails, hotels, ferry connectivity, and regional freeways.
  • ~40,000 SF large open floor plates, 125 LBS/ SF (Floor load capacity), 16' Height typical floor-to-floor height, 22' X 33' Typical Column Spacing
  • Waterfront life sciences campus positioned in the heart of the Bay Area biotech ecosystem.

Park Facts

Total Space Available 454,736 SF
Min. Divisible 16,236 SF
Max. Contiguous 304,500 SF
Park Type Office Park
Features
24 Hour Access
  • Conferencing Facility, Property Manager on Site, Restaurant, Signage, Waterfront, Roof Terrace, Storage Space, Car Charging Station, Monument Signage, Air Conditioning

All Available Spaces(12)

Display Rental Rate as

Kilroy Oyster Point
363 Oyster Point Blvd - Phase II - Building D
21,750 - 304,500 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Flex/A
Building Size
304,500 SF
Lot Size
3.79 AC
Year Built
2023
Zoning
M20000
  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Condition
  • Available
  • 1st Floor
  • 21,750-43,500 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • 2nd Floor
  • 21,750-43,500 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • 3rd Floor
  • 21,750-43,500 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • 4th Floor
  • 21,750-43,500 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • 5th Floor
  • 21,750-43,500 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • 6th Floor
  • 21,750-43,500 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • 7th Floor
  • 21,750-43,500 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
Space Size Term Rental Rate Space Use Condition Available
1st Floor 21,750-43,500 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
2nd Floor 21,750-43,500 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
3rd Floor 21,750-43,500 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
4th Floor 21,750-43,500 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
5th Floor 21,750-43,500 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
6th Floor 21,750-43,500 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
7th Floor 21,750-43,500 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
Kilroy Oyster Point
363 Oyster Point Blvd - Phase II - Building D
21,750 - 304,500 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Flex/A
Building Size
304,500 SF
Lot Size
3.79 AC
Year Built
2023
Zoning
M20000

363 Oyster Point Blvd - 1st Floor

Size
21,750-43,500 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now

363 Oyster Point Blvd - 2nd Floor

Size
21,750-43,500 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now

363 Oyster Point Blvd - 3rd Floor

Size
21,750-43,500 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now

363 Oyster Point Blvd - 4th Floor

Size
21,750-43,500 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now

363 Oyster Point Blvd - 5th Floor

Size
21,750-43,500 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now

363 Oyster Point Blvd - 6th Floor

Size
21,750-43,500 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now

363 Oyster Point Blvd - 7th Floor

Size
21,750-43,500 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now
Kilroy Oyster Point
365 Oyster Point Blvd - Phase II - Building F
16,236 - 150,236 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Flex/A
Building Size
304,500 SF
Lot Size
3.79 AC
Year Built
2024
Zoning
M20000
  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Condition
  • Available
  • 3rd Floor
  • 20,000 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • -
  • Now
  • 4th Floor
  • 24,000 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • -
  • Now
  • 5th Floor
  • 16,236 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 106,236 SF of adjacent space
  • 6th Floor
  • 45,000 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 106,236 SF of adjacent space
  • 7th Floor
  • 45,000 SF
  • 3-5 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Flex
  • Shell Space
  • Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Divisible occupancy
  • Can be combined with additional space(s) for up to 106,236 SF of adjacent space
Space Size Term Rental Rate Space Use Condition Available
3rd Floor 20,000 SF Negotiable Upon Request Upon Request Upon Request Upon Request Flex - Now
4th Floor 24,000 SF Negotiable Upon Request Upon Request Upon Request Upon Request Flex - Now
5th Floor 16,236 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
6th Floor 45,000 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
7th Floor 45,000 SF 3-5 Years Upon Request Upon Request Upon Request Upon Request Flex Shell Space Now
Kilroy Oyster Point
365 Oyster Point Blvd - Phase II - Building F
16,236 - 150,236 SF | Upon Request Upon Request Upon Request Upon Request Upon Request Upon Request | View Building Details
Building Type/Class
Flex/A
Building Size
304,500 SF
Lot Size
3.79 AC
Year Built
2024
Zoning
M20000

365 Oyster Point Blvd - 3rd Floor

Size
20,000 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
-
Available
Now

365 Oyster Point Blvd - 4th Floor

Size
24,000 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
-
Available
Now

365 Oyster Point Blvd - 5th Floor

Size
16,236 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now

365 Oyster Point Blvd - 6th Floor

Size
45,000 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now

365 Oyster Point Blvd - 7th Floor

Size
45,000 SF
Term
3-5 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Flex
Condition
Shell Space
Available
Now

363 Oyster Point Blvd - 1st Floor

Size 21,750-43,500 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • Divisible occupancy

363 Oyster Point Blvd - 2nd Floor

Size 21,750-43,500 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • Divisible occupancy

363 Oyster Point Blvd - 3rd Floor

Size 21,750-43,500 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • Divisible occupancy

363 Oyster Point Blvd - 4th Floor

Size 21,750-43,500 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • Divisible occupancy

363 Oyster Point Blvd - 5th Floor

Size 21,750-43,500 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • Divisible occupancy

363 Oyster Point Blvd - 6th Floor

Size 21,750-43,500 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • Divisible occupancy

363 Oyster Point Blvd - 7th Floor

Size 21,750-43,500 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 304,500 SF of adjacent space
  • Divisible occupancy

365 Oyster Point Blvd - 3rd Floor

Size 20,000 SF
Term Negotiable
Rental Rate Upon Request
Space Use Flex
Condition -
Available Now

365 Oyster Point Blvd - 4th Floor

Size 24,000 SF
Term Negotiable
Rental Rate Upon Request
Space Use Flex
Condition -
Available Now

365 Oyster Point Blvd - 5th Floor

Size 16,236 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 106,236 SF of adjacent space
  • Divisible occupancy

365 Oyster Point Blvd - 6th Floor

Size 45,000 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 106,236 SF of adjacent space
  • Divisible occupancy

365 Oyster Point Blvd - 7th Floor

Size 45,000 SF
Term 3-5 Years
Rental Rate Upon Request
Space Use Flex
Condition Shell Space
Available Now

Phase 2 is the next wave of lab and office space designed for innovators and trailblazers. The leading-edge design offers an energizing environment full of amenities that support wellness, sustainability, and productivity. 865,000 sq. ft.; 3 Buildings; 7-8 stories. Actively Leasing.

  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 106,236 SF of adjacent space
  • Divisible occupancy

Park Overview

Kilroy Oyster Point Phase 2 is now delivering: three state-of-the-art buildings totaling approximately 865,000 square feet in the heart of South San Francisco—the birthplace of biotechnology. Kilroy Oyster Point Phase 2 is a premier waterfront life sciences environment designed to accelerate scientific innovation within one of the Bay Area’s most established biotech clusters. Set along Oyster Point’s shoreline, the campus blends purpose-built lab and office buildings with expansive outdoor zones, providing an energized setting that supports collaboration, wellness, and productivity. Tenants benefit from next-generation infrastructure including significant floor load capacities, large open floor plates, and LEED Gold–targeted design, all arranged within an interconnected outdoor village featuring amphitheater seating, a conference center, fitness amenities, and Farewinds restaurant and café. The location offers both inspiration and convenience, just steps from beaches, trails, hotels, and immediate access to ferry service and major freeways, making Phase 2 a destination for companies seeking an elevated, amenity-driven research workplace.

  • 24 Hour Access
  • Conferencing Facility
  • Property Manager on Site
  • Restaurant
  • Signage
  • Waterfront
  • Roof Terrace
  • Storage Space
  • Car Charging Station
  • Monument Signage
  • Air Conditioning
  • Listing ID: 21282072

  • Date on Market: 2025-12-04

  • Last Updated:

  • Address: 384 Oyster Point Blvd, South San Francisco, CA 94080

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