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Highlights

  • Convenient access to Pacific Coast Highway, 73 Toll Road, and Interstates 405 and 55.

All Available Spaces(3)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor, Ste 106
  • 994 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • 90 Days

Medical space available. Call to show.

  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Mostly Open Floor Plan Layout
  • 2nd Floor, Ste 210
  • 1,488 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now

Medical space available. Call to show.

  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Mostly Open Floor Plan Layout
  • 6th Floor, Ste 604
  • 2,576 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Medical
  • Full Build-Out
  • Now

Medical space available. Call to show.

  • Listed lease rate plus proportional share of the utilities and cleaning cost
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Health Care Space
  • Space is in Excellent Condition
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor, Ste 106 994 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out 90 Days
2nd Floor, Ste 210 1,488 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now
6th Floor, Ste 604 2,576 SF Negotiable Upon Request Upon Request Upon Request Upon Request Medical Full Build-Out Now

1st Floor, Ste 106

Size
994 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Build-Out
Full Build-Out
Available
90 Days

2nd Floor, Ste 210

Size
1,488 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Build-Out
Full Build-Out
Available
Now

6th Floor, Ste 604

Size
2,576 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Medical
Build-Out
Full Build-Out
Available
Now

1st Floor, Ste 106

Size 994 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Build-Out Full Build-Out
Available 90 Days

Medical space available. Call to show.

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition

2nd Floor, Ste 210

Size 1,488 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Build-Out Full Build-Out
Available Now

Medical space available. Call to show.

  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition

6th Floor, Ste 604

Size 2,576 SF
Term Negotiable
Rental Rate Upon Request
Space Use Medical
Build-Out Full Build-Out
Available Now

Medical space available. Call to show.

  • Listed lease rate plus proportional share of the utilities and cleaning cost
  • Fully Built-Out as Health Care Space
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition

Property Overview

400 Newport Center Drive, also known as Newport Center Medical Plaza, offers a premier medical office environment in the heart of Newport Beach’s prestigious business district. This multi-tenant property provides a professional setting with modernized interiors and flexible suite configurations designed to accommodate a range of healthcare and office users. The building features convenient surface parking, elevator service, and a well-maintained common area, ensuring ease of access for patients and staff. Located within the sought-after Newport Center area, the property is surrounded by high-end retail, dining, and hospitality options, including Fashion Island, and offers quick connectivity to Pacific Coast Highway, the 73 Toll Road, and major freeways. With its prime location, professional management, and proximity to John Wayne Airport, 400 Newport Center Drive is an exceptional choice for medical practitioners and businesses seeking a high-profile address in Orange County.

  • Restaurant
  • Signage
  • Wheelchair Accessible
  • Central Heating
  • Recessed Lighting
  • Outdoor Seating
  • Air Conditioning
  • Smoke Detector

Property Facts

Building Type
Office
Year Built
1961
Building Height
7 Stories
Building Size
68,000 SF
Building Class
B
Typical Floor Size
12,408 SF
Unfinished Ceiling Height
11’
Parking
28 Surface Parking Spaces
200 Covered Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 4th
  • Allergy & Asthma Adults Children
  • Health Care and Social Assistance
  • 3rd
  • Arthur J Helliwell Inc
  • Health Care and Social Assistance
  • 6th
  • Bruce R. Harkins, D.D.S.
  • Health Care and Social Assistance
  • 1st
  • Health Mart Pharmacy
  • Retailer
  • 7th
  • Hersch Pediatric Dentistry
  • Health Care and Social Assistance
  • 3rd
  • Jon M Grazer, MD, MPH, Inc.
  • Health Care and Social Assistance
  • 5th
  • Newport Center Medical Group
  • Health Care and Social Assistance
  • 2nd
  • Randall Perkins, D.D.S.
  • Health Care and Social Assistance
  • 6th
  • United Medical Doctors
  • Health Care and Social Assistance
  • 7th
  • West Dermatology-Newport Beach
  • Health Care and Social Assistance
Very walkable
80/100
Very drivable
80/100
Some public transit
40/100
Moderately bikeable
60/100
  • Listing ID: 37370948

  • Date on Market: 2026-02-03

  • Last Updated:

  • Address: 400 Newport Center Dr, Newport Beach, CA 92660

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