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Highlights

  • Easy access to major roads and public transit
  • Located in Manayunk, a lively Philadelphia neighborhood
  • Features 24-hour access and air conditioning
  • Historic building renovated in 2014

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 2nd Floor - 200
  • 350 SF
  • Negotiable
  • $38.35 CAD/SF/YR $3.20 CAD/SF/MO $13,424 CAD/YR $1,119 CAD/MO
  • Flex
  • Full Build-Out
  • 2026-10-01
  • Rate includes utilities, building services and property expenses
  • High Ceilings
  • Exposed Ceiling
  • Central Air and Heating
  • After Hours HVAC Available
  • Wheelchair Accessible
Space Size Term Rental Rate Space Use Build-Out Available
2nd Floor - 200 350 SF Negotiable $38.35 CAD/SF/YR $3.20 CAD/SF/MO $13,424 CAD/YR $1,119 CAD/MO Flex Full Build-Out 2026-10-01

2nd Floor - 200

Size
350 SF
Term
Negotiable
Rental Rate
$38.35 CAD/SF/YR $3.20 CAD/SF/MO $13,424 CAD/YR $1,119 CAD/MO
Space Use
Flex
Build-Out
Full Build-Out
Available
2026-10-01
Spaces are matched based on search filters: space use, price, and size
  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 2nd Floor - 200
  • 350 SF
  • Negotiable
  • $38.35 CAD/SF/YR $3.20 CAD/SF/MO $13,424 CAD/YR $1,119 CAD/MO
  • Flex
  • Full Build-Out
  • 2026-10-01
  • Rate includes utilities, building services and property expenses
  • High Ceilings
  • Exposed Ceiling
  • Central Air and Heating
  • After Hours HVAC Available
  • Wheelchair Accessible
  • 2nd Floor, Ste 201
  • 525 SF
  • Negotiable
  • $32.16 CAD/SF/YR $2.68 CAD/SF/MO $16,886 CAD/YR $1,407 CAD/MO
  • Office
  • Full Build-Out
  • Now
  • Rate includes utilities, building services and property expenses
  • Open Floor Plan Layout
  • Space is in Excellent Condition
  • High Ceilings
  • Natural Light
  • Hardwood Floors
  • Fully Built-Out as Standard Office
  • Fits 2 - 5 People
  • Central Air and Heating
  • Exposed Ceiling
  • Open-Plan
  • Wheelchair Accessible
Space Size Term Rental Rate Space Use Build-Out Available
2nd Floor - 200 350 SF Negotiable $38.35 CAD/SF/YR $3.20 CAD/SF/MO $13,424 CAD/YR $1,119 CAD/MO Flex Full Build-Out 2026-10-01
2nd Floor, Ste 201 525 SF Negotiable $32.16 CAD/SF/YR $2.68 CAD/SF/MO $16,886 CAD/YR $1,407 CAD/MO Office Full Build-Out Now

2nd Floor - 200

Size
350 SF
Term
Negotiable
Rental Rate
$38.35 CAD/SF/YR $3.20 CAD/SF/MO $13,424 CAD/YR $1,119 CAD/MO
Space Use
Flex
Build-Out
Full Build-Out
Available
2026-10-01

2nd Floor, Ste 201

Size
525 SF
Term
Negotiable
Rental Rate
$32.16 CAD/SF/YR $2.68 CAD/SF/MO $16,886 CAD/YR $1,407 CAD/MO
Space Use
Office
Build-Out
Full Build-Out
Available
Now

2nd Floor - 200

Size 350 SF
Term Negotiable
Rental Rate $38.35 CAD/SF/YR
Space Use Flex
Build-Out Full Build-Out
Available 2026-10-01

  • Rate includes utilities, building services and property expenses
  • Central Air and Heating
  • High Ceilings
  • After Hours HVAC Available
  • Exposed Ceiling
  • Wheelchair Accessible

2nd Floor, Ste 201

Size 525 SF
Term Negotiable
Rental Rate $32.16 CAD/SF/YR
Space Use Office
Build-Out Full Build-Out
Available Now

  • Rate includes utilities, building services and property expenses
  • Fully Built-Out as Standard Office
  • Open Floor Plan Layout
  • Fits 2 - 5 People
  • Space is in Excellent Condition
  • Central Air and Heating
  • High Ceilings
  • Exposed Ceiling
  • Natural Light
  • Open-Plan
  • Hardwood Floors
  • Wheelchair Accessible

Property Overview

Located in the heart of Manayunk, 4001 Main Street is a historic Class B office building blending classic architecture with modern upgrades. Built in 1890 and renovated in 2014, the property spans 15,624 SF across three floors and sits on 0.29 acres. With masonry construction, sprinklers, and air conditioning, the building offers a secure and comfortable workspace. Tenancy includes a mix of professional services, healthcare, and creative firms, creating a vibrant business community.

  • 24 Hour Access
  • Bus Line
  • Basement
  • Central Heating
  • Air Conditioning

Property Facts

Building Type
Office
Year Built/Renovated
1890/2014
Building Height
3 Stories
Building Size
15,624 SF
Building Class
C
Typical Floor Size
5,208 SF

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 2nd
  • Amee Psychotherapy, LLC
  • Health Care and Social Assistance
  • 2nd
  • APOP
  • Professional, Scientific, and Technical Services
  • 1st
  • Busy Bee Transit
  • Transportation and Warehousing
  • 2nd
  • CaidBrandCo
  • Manufacturing
  • 2nd
  • Care R Us Home Care Agency, LLC
  • Health Care and Social Assistance
  • 1st
  • Commonwealth of Pennsylvania
  • Public Administration
  • Multiple
  • DesignBlendz
  • Professional, Scientific, and Technical Services
  • 1st
  • Fettline Enterprises, LLC
  • Transportation and Warehousing
  • 1st
  • Safi Skinsentials
  • Services
  • 1st
  • Vexillum Law
  • Professional, Scientific, and Technical Services
Moderately walkable
60/100
Exceptionally drivable
100/100
Good public transit
60/100
Very bikeable
80/100
  • Listing ID: 38368051

  • Date on Market: 2026-07-21

  • Last Updated:

  • Address: 4001 Main St, Philadelphia, PA 19127

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