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Isom Road Business Park San Antonio, TX 78216 498 - 4,520 SF of Space Available

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PARK HIGHLIGHTS

  • Outstanding North Central Location
  • Attractive Business Park Setting
  • Exterior Signage & Visibility
  • Immediate Access to US 281, San Pedro Ave & Loop 410
  • Grade-Level Doors
  • Ample Parking

PARK FACTS

Total Space Available 4,520 SF
Park Type Office Park

ALL AVAILABLE SPACES(3)

Display Rental Rate as

Isom Road Business Park
401 Isom Rd - Building 200
498 SF | $22.24 CAD/SF/YR $1.85 CAD/SF/MO $239.39 CAD/m²/YR $19.95 CAD/m²/MO $922.95 CAD/MO $11,075 CAD/YR | View Building Details
Building Type/Class
Office/B
Year Built
1976
Building Size
11,727 SF
Building Height
1 Story
Typical Floor Size
11,727 SF
Parking
25 Spaces
  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor, Ste 230
  • 498 SF
  • Negotiable
  • $22.24 CAD/SF/YR $1.85 CAD/SF/MO $11,075 CAD/YR $922.95 CAD/MO
  • Office
  • -
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • Space is in Excellent Condition
  • Fits 2 - 4 People
Space Size Term Rental Rate Space Use Condition Available
1st Floor, Ste 230 498 SF Negotiable $22.24 CAD/SF/YR $1.85 CAD/SF/MO $11,075 CAD/YR $922.95 CAD/MO Office - Now
Isom Road Business Park
401 Isom Rd - Building 200
498 SF | $22.24 CAD/SF/YR $1.85 CAD/SF/MO $239.39 CAD/m²/YR $19.95 CAD/m²/MO $922.95 CAD/MO $11,075 CAD/YR | View Building Details
Building Type/Class
Office/B
Year Built
1976
Building Size
11,727 SF
Building Height
1 Story
Typical Floor Size
11,727 SF
Parking
25 Spaces

401 Isom Rd - 1st Floor - Ste 230

Size
498 SF
Term
Negotiable
Rental Rate
$22.24 CAD/SF/YR $1.85 CAD/SF/MO $11,075 CAD/YR $922.95 CAD/MO
Space Use
Office
Condition
-
Available
Now
Isom Road Business Park
401 Isom Rd - Building 400
1,731 - 4,022 SF | $19.46 CAD/SF/YR $1.62 CAD/SF/MO $209.46 CAD/m²/YR $17.46 CAD/m²/MO $2,807 - $6,522 CAD/MO $33,685 - $78,268 CAD/YR | View Building Details
Building Type/Class
Flex/B
Building Size
18,932 SF
Lot Size
5.25 AC
Year Built
1976
Drive In Bays
11
Zoning
C-3 - General Commercial District
  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor - 410
  • 2,291 SF
  • Negotiable
  • $19.46 CAD/SF/YR $1.62 CAD/SF/MO $44,583 CAD/YR $3,715 CAD/MO
  • Flex
  • -
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • Two (2) Grade-Level Doors
  • Approx. 80% Office and 20% Warehouse
  • Space is in Excellent Condition
  • Two (2) Restrooms
  • 1st Floor - 445
  • 1,731 SF
  • Negotiable
  • $19.46 CAD/SF/YR $1.62 CAD/SF/MO $33,685 CAD/YR $2,807 CAD/MO
  • Flex
  • -
  • Now
  • Lease rate does not include utilities, property expenses or building services
  • One (1) Grade Level Door
  • Space is in Excellent Condition
Space Size Term Rental Rate Space Use Condition Available
1st Floor - 410 2,291 SF Negotiable $19.46 CAD/SF/YR $1.62 CAD/SF/MO $44,583 CAD/YR $3,715 CAD/MO Flex - Now
1st Floor - 445 1,731 SF Negotiable $19.46 CAD/SF/YR $1.62 CAD/SF/MO $33,685 CAD/YR $2,807 CAD/MO Flex - Now
Isom Road Business Park
401 Isom Rd - Building 400
1,731 - 4,022 SF | $19.46 CAD/SF/YR $1.62 CAD/SF/MO $209.46 CAD/m²/YR $17.46 CAD/m²/MO $2,807 - $6,522 CAD/MO $33,685 - $78,268 CAD/YR | View Building Details
Building Type/Class
Flex/B
Building Size
18,932 SF
Lot Size
5.25 AC
Year Built
1976
Drive In Bays
11
Zoning
C-3 - General Commercial District

401 Isom Rd - 1st Floor - 410

Size
2,291 SF
Term
Negotiable
Rental Rate
$19.46 CAD/SF/YR $1.62 CAD/SF/MO $44,583 CAD/YR $3,715 CAD/MO
Space Use
Flex
Condition
-
Available
Now

401 Isom Rd - 1st Floor - 445

Size
1,731 SF
Term
Negotiable
Rental Rate
$19.46 CAD/SF/YR $1.62 CAD/SF/MO $33,685 CAD/YR $2,807 CAD/MO
Space Use
Flex
Condition
-
Available
Now

401 Isom Rd - 1st Floor - Ste 230

Size 498 SF
Term Negotiable
Rental Rate $22.24 CAD/SF/YR
Space Use Office
Condition -
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fits 2 - 4 People
  • Space is in Excellent Condition

401 Isom Rd - 1st Floor - 410

Size 2,291 SF
Term Negotiable
Rental Rate $19.46 CAD/SF/YR
Space Use Flex
Condition -
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Space is in Excellent Condition
  • Two (2) Grade-Level Doors
  • Two (2) Restrooms
  • Approx. 80% Office and 20% Warehouse

401 Isom Rd - 1st Floor - 445

Size 1,731 SF
Term Negotiable
Rental Rate $19.46 CAD/SF/YR
Space Use Flex
Condition -
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Space is in Excellent Condition
  • One (1) Grade Level Door

SITE PLAN

PARK OVERVIEW

Now available at Isom Road Business Park, this versatile flex/service center offers ±498 to ±2,291 SF in a highly sought-after North Central San Antonio location. The property features immediate access to US 281, San Pedro Avenue, and Loop 410, making it an ideal solution for businesses seeking convenience, connectivity, and visibility. Set within an attractive business park environment, the space includes grade-level doors, exterior signage opportunities, and ample on-site parking. Designed to support a range of uses, this well-located property delivers functionality, accessibility, and a professional setting for growing and established businesses alike. Contact us today to schedule a tour.

  • Listing ID: 28874542

  • Date on Market: 2026-01-12

  • Last Updated:

  • Address: 401 Isom Rd, San Antonio, TX 78216

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