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412 6th Ave NW
Rochester, MN 55901
Exceptional Development Opportunity -2.8 AC · Land For Sale · 2.80 AC

Investment Highlights

  • Elite Location: Approximately 2.8 prime acres located just blocks from the world-renowned Mayo Clinic campus.
  • High-Intensity R-4 Zoning: Flexible, high-density zoning allows for the "highest intensity" residential, hospitality, or mixed-use projects.
  • Scalable Potential: One of the few remaining large-scale redevelopment footprints in Rochester’s core medical and research corridor.
  • DMC District Advantage: Positioned within the Destination Medical Center zone, offering unique development incentives and public-private support.
  • Massive Economic Driver: Directly benefits from Mayo Clinic’s multi-billion dollar "Bold. Forward. Unbound." expansion and global patient draw.
  • Ready for Growth: Exceptional visibility and access to support luxury multi-family, medical office, or flagship hospitality.

Executive Summary

Exceptional opportunity to acquire approximately 2.8 acres of prime redevelopment land ideally positioned blocks from the world-renowned Mayo Clinic. Located within the DMC (Destination Medical Center) zoning district, this property sits in one of the most dynamic and rapidly growing medical and research corridors in the country.
The site offers outstanding potential for residential, hospitality, or mixed-use development, benefiting from the significant public and private investment driving growth in the surrounding area. The site is ideally situated 1.5 blocks from a 2.4M SF Mayo Clinic expansion project, which will begin operations in 2028 and employ 6,000 healthcare workers by 2030. The site's proximity to Mayo Clinic provides immediate access to a globally recognized healthcare hub, drawing professionals, patients, and visitors from around the world.
With strong visibility, convenient access, and flexible redevelopment possibilities, this property offers developers and investors a rare chance to capitalize on the continued growth of Rochester and the Mayo Clinic.
The site should also benefit from planned City of Rochester infrastructure improvements, which include enhanced bicycle and pedestrian paths on adjacent streets.
For a detailed vision of the site’s potential, see the "Reimagining Sixth Ave. W." link in the resources section.

Property Facts

Sale Type Investment
Sale Condition Redevelopment Project
No. Lots 1
Property Type Land
Property Subtype Commercial
Proposed Use
Commercial
  • Retail
  • Mixed Use
  • Multifamily
  • Apartment Units
  • Apartment Units - Dorms
  • Apartment Units - Senior
  • Storefront, Retail or Residential
Total Lot Size 2.80 AC
Zoning R4 - R-4 Zoning: High-intensity multifamily residential, plus supportive commercial and civic uses of similar scale and density.

1 Lot Available

Lot

Lot Size 2.80 AC

Description

Exceptional opportunity to acquire approximately 2.8 acres of prime redevelopment land ideally positioned blocks from the world-renowned Mayo Clinic. Located within the DMC (Destination Medical Center) zoning district, this property sits in one of the most dynamic and rapidly growing medical and research corridors in the country. The site offers outstanding potential for residential, hospitality, or mixed-use development, benefiting from the significant public and private investment driving growth in the surrounding area. The site is ideally situated 1.5 blocks from a 2.4M SF Mayo Clinic expansion project, which will begin operations in 2028 and employ 6,000 healthcare workers by 2030. The site's proximity to Mayo Clinic provides immediate access to a globally recognized healthcare hub, drawing professionals, patients, and visitors from around the world. With strong visibility, convenient access, and flexible redevelopment possibilities, this property offers developers and investors a rare chance to capitalize on the continued growth of Rochester and the Mayo Clinic. The site should also benefit from planned City of Rochester infrastructure improvements, which include enhanced bicycle and pedestrian paths on adjacent streets. For a detailed vision of the site’s potential, see the "Reimagining Sixth Ave. W." link in the resources section.

  • Listing ID: 39747778

  • Date on Market: 2026-03-12

  • Last Updated:

  • Address: 412 6th Ave NW, Rochester, MN 55901

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