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River Oaks Medical Tower 4126 Southwest Fwy 306 - 106,084 SF of 4-Star Office/Medical Space Available in Houston, TX 77027

Office Spaces Texas Houston 4126 Southwest Fwy, Houston, TX 77027

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Highlights

  • Unparalleled visibility and exposure with panoramic perspectives from the freeway and surrounding areas.
  • Adjacent to the River Oaks Medical Center, Twelve Oaks Hospital, and a six-minute drive to Memorial Hermann Hospital and Houston Methodist Hospital.
  • Physicians in the building range from physical therapists and cosmetic surgeons to outpatient surgical experts and general medical practitioners.
  • Ideal location for any medical user with easy access to the Southwest Freeway, Loop 610, The Galleria, Downtown, and Texas Medical Center.
  • Direct access to affluent patient populations residing in proximity, including West University, Afton Oaks, River Oaks, and Tanglewood.

All Available Spaces(25)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 2nd Floor, Ste 200
  • 8,232 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • 3rd Floor, Ste 310
  • 1,390 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Can be combined with additional space(s) for up to 5,149 SF of adjacent space
  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • 3rd Floor, Ste 320
  • 306 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 5,149 SF of adjacent space
  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • 3rd Floor, Ste 330
  • 3,453 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Partial Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Spacious office/Medical suite with 3,453 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Partially Built-Out as Standard Office
  • Can be combined with additional space(s) for up to 5,149 SF of adjacent space
  • 4th Floor, Ste 400
  • 9,111 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Shell Space
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Spacious office/Medical suite with 9,111 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Full Floor Opportunity
  • Open Floor Plan Layout
  • 6th Floor, Ste 600E
  • 1,766 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Partial Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Spacious office/Medical suite with 1,766 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Partially Built-Out as Standard Office
  • 6th Floor, Ste 600G
  • 4,746 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Partial Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Spacious office/Medical suite with 4,746 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Partially Built-Out as Standard Office
  • 7th Floor, Ste 700
  • 3,741 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Partial Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Spacious office/Medical suite with 3,741 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Partially Built-Out as Standard Office
  • Can be combined with additional space(s) for up to 8,084 SF of adjacent space
  • 7th Floor, Ste 710
  • 3,353 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Partial Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Spacious office/Medical suite with 3,353 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Ideal training rooms; available Fall 2024
  • Partially Built-Out as Standard Medical Space
  • Can be combined with additional space(s) for up to 8,084 SF of adjacent space
  • 7th Floor, Ste 730
  • 990 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Spacious office/Medical suite with 900 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Fully Built-Out as Standard Medical Space
  • Can be combined with additional space(s) for up to 8,084 SF of adjacent space
  • 8th Floor, Ste 800
  • 4,000 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • 8th Floor, Ste 820
  • 3,725 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Excellent building lobby exposure, ready for space planning.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Fully Built-Out as Standard Medical Space
  • 9th Floor, Ste 999
  • 8,232 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • -
  • 30 Days
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • 10th Floor, Ste 1000
  • 3,078 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Spec Suite
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • Can be combined with additional space(s) for up to 8,299 SF of adjacent space
  • Office intensive layout
  • 10th Floor, Ste 1020
  • 2,500 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Spec Suite
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • Can be combined with additional space(s) for up to 8,299 SF of adjacent space
  • Office intensive layout
  • 10th Floor, Ste 1030
  • 2,721 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Spec Suite
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • Can be combined with additional space(s) for up to 8,299 SF of adjacent space
  • Office intensive layout
  • Private Restrooms
  • 12th Floor, Ste 1210
  • 2,096 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • -
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • 12th Floor, Ste 1220
  • 1,675 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Clinical space with great views throughout.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Fully Built-Out as Standard Medical Space
  • Can be combined with additional space(s) for up to 3,616 SF of adjacent space
  • 12th Floor, Ste 1230
  • 1,941 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Partial Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Spacious office/Medical suite with 1,941 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Partially Built-Out as Standard Office
  • Can be combined with additional space(s) for up to 3,616 SF of adjacent space
  • 13th Floor, Ste 1300
  • 8,232 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • 90 Days
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • Office intensive layout
  • 14th Floor, Ste 1400
  • 8,604 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Full floor opportunity; available Fall 2024.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Fully Built-Out as Standard Office
  • Can be combined with additional space(s) for up to 17,185 SF of adjacent space
  • 15th Floor, Ste 1500
  • 8,581 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Full floor opportunity; available Fall 2024.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Fully Built-Out as Standard Office
  • Can be combined with additional space(s) for up to 17,185 SF of adjacent space
  • 16th Floor, Ste 1600
  • 8,604 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • 17th Floor, Ste 1730
  • 2,912 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 5,007 SF of adjacent space
  • 17th Floor, Ste 1750
  • 2,095 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Partial Build-Out
  • Now
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan

Spacious office/Medical suite with 2,095 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Partially Built-Out as Standard Office
  • Can be combined with additional space(s) for up to 5,007 SF of adjacent space
Space Size Term Rental Rate Space Use Build-Out Available
2nd Floor, Ste 200 8,232 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
3rd Floor, Ste 310 1,390 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
3rd Floor, Ste 320 306 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
3rd Floor, Ste 330 3,453 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Partial Build-Out Now
4th Floor, Ste 400 9,111 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Shell Space Now
6th Floor, Ste 600E 1,766 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Partial Build-Out Now
6th Floor, Ste 600G 4,746 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Partial Build-Out Now
7th Floor, Ste 700 3,741 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Partial Build-Out Now
7th Floor, Ste 710 3,353 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Partial Build-Out Now
7th Floor, Ste 730 990 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
8th Floor, Ste 800 4,000 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
8th Floor, Ste 820 3,725 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
9th Floor, Ste 999 8,232 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical - 30 Days
10th Floor, Ste 1000 3,078 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Spec Suite Now
10th Floor, Ste 1020 2,500 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Spec Suite Now
10th Floor, Ste 1030 2,721 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Spec Suite Now
12th Floor, Ste 1210 2,096 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical - Now
12th Floor, Ste 1220 1,675 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
12th Floor, Ste 1230 1,941 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Partial Build-Out Now
13th Floor, Ste 1300 8,232 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out 90 Days
14th Floor, Ste 1400 8,604 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
15th Floor, Ste 1500 8,581 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
16th Floor, Ste 1600 8,604 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
17th Floor, Ste 1730 2,912 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now
17th Floor, Ste 1750 2,095 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office/Medical Partial Build-Out Now

2nd Floor, Ste 200

Size
8,232 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 310

Size
1,390 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 320

Size
306 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 330

Size
3,453 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Partial Build-Out
Available
Now

4th Floor, Ste 400

Size
9,111 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Shell Space
Available
Now

6th Floor, Ste 600E

Size
1,766 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Partial Build-Out
Available
Now

6th Floor, Ste 600G

Size
4,746 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Partial Build-Out
Available
Now

7th Floor, Ste 700

Size
3,741 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Partial Build-Out
Available
Now

7th Floor, Ste 710

Size
3,353 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Partial Build-Out
Available
Now

7th Floor, Ste 730

Size
990 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

8th Floor, Ste 800

Size
4,000 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

8th Floor, Ste 820

Size
3,725 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

9th Floor, Ste 999

Size
8,232 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
-
Available
30 Days

10th Floor, Ste 1000

Size
3,078 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Spec Suite
Available
Now

10th Floor, Ste 1020

Size
2,500 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Spec Suite
Available
Now

10th Floor, Ste 1030

Size
2,721 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Spec Suite
Available
Now

12th Floor, Ste 1210

Size
2,096 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
-
Available
Now

12th Floor, Ste 1220

Size
1,675 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

12th Floor, Ste 1230

Size
1,941 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Partial Build-Out
Available
Now

13th Floor, Ste 1300

Size
8,232 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
90 Days

14th Floor, Ste 1400

Size
8,604 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

15th Floor, Ste 1500

Size
8,581 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

16th Floor, Ste 1600

Size
8,604 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

17th Floor, Ste 1730

Size
2,912 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
Now

17th Floor, Ste 1750

Size
2,095 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Partial Build-Out
Available
Now
1 of 1
Videos
Matterport 3D Exterior
Matterport 3D Tour
Photos
Street View Street
Map
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 200 - 8,232 SF

2nd Floor, Ste 200

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 8,232 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Office intensive layout
  • Space is in Excellent Condition
1 of 1
Videos
Matterport 3D Exterior
Matterport 3D Tour
Photos
Street View Street
Map
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 310 - 1,390 SF

3rd Floor, Ste 310

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 1,390 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Office intensive layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 5,149 SF of adjacent space
1 of 1
Videos
Matterport 3D Exterior
Matterport 3D Tour
Photos
Street View Street
Map
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 320 - 306 SF

3rd Floor, Ste 320

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 306 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 5,149 SF of adjacent space
1 of 1
Videos
Matterport 3D Exterior
Matterport 3D Tour
Photos
Street View Street
Map
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 330 - 3,453 SF

3rd Floor, Ste 330

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 3,453 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Partial Build-Out
Available Now

Spacious office/Medical suite with 3,453 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Partially Built-Out as Standard Office
  • Office intensive layout
  • Can be combined with additional space(s) for up to 5,149 SF of adjacent space
1 of 1
Videos
Matterport 3D Exterior
Matterport 3D Tour
Photos
Street View Street
Map
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 400 - 9,111 SF

4th Floor, Ste 400

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 9,111 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Shell Space
Available Now

Spacious office/Medical suite with 9,111 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Open Floor Plan Layout
  • Full Floor Opportunity
1 of 1
Videos
Matterport 3D Exterior
Matterport 3D Tour
Photos
Street View Street
Map
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 600E - 1,766 SF

6th Floor, Ste 600E

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 1,766 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Partial Build-Out
Available Now

Spacious office/Medical suite with 1,766 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Partially Built-Out as Standard Office
  • Office intensive layout
1 of 1
Videos
Matterport 3D Exterior
Matterport 3D Tour
Photos
Street View Street
Map
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 600G - 4,746 SF

6th Floor, Ste 600G

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 4,746 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Partial Build-Out
Available Now

Spacious office/Medical suite with 4,746 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Partially Built-Out as Standard Office
  • Office intensive layout
1 of 1
Videos
Matterport 3D Exterior
Matterport 3D Tour
Photos
Street View Street
Map
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 700 - 3,741 SF

7th Floor, Ste 700

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 3,741 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Partial Build-Out
Available Now

Spacious office/Medical suite with 3,741 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Partially Built-Out as Standard Office
  • Office intensive layout
  • Can be combined with additional space(s) for up to 8,084 SF of adjacent space
1 of 1
Videos
Matterport 3D Exterior
Matterport 3D Tour
Photos
Street View Street
Map
4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 710 - 3,353 SF

7th Floor, Ste 710

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 3,353 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Partial Build-Out
Available Now

Spacious office/Medical suite with 3,353 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Partially Built-Out as Standard Medical Space
  • Office intensive layout
  • Can be combined with additional space(s) for up to 8,084 SF of adjacent space
  • Ideal training rooms; available Fall 2024
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 730 - 990 SF

7th Floor, Ste 730

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 990 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Spacious office/Medical suite with 900 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Can be combined with additional space(s) for up to 8,084 SF of adjacent space
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 800 - 4,000 SF

8th Floor, Ste 800

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 4,000 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 820 - 3,725 SF

8th Floor, Ste 820

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 3,725 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Excellent building lobby exposure, ready for space planning.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 999 - 8,232 SF

9th Floor, Ste 999

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 8,232 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out -
Available 30 Days

  • Lease rate does not include utilities, property expenses or building services
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1000 - 3,078 SF

10th Floor, Ste 1000

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 3,078 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Spec Suite
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Can be combined with additional space(s) for up to 8,299 SF of adjacent space
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1020 - 2,500 SF

10th Floor, Ste 1020

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 2,500 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Spec Suite
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Can be combined with additional space(s) for up to 8,299 SF of adjacent space
1 of 1
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1030 - 2,721 SF

10th Floor, Ste 1030

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 2,721 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Spec Suite
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Office intensive layout
  • Can be combined with additional space(s) for up to 8,299 SF of adjacent space
  • Private Restrooms
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1210 - 2,096 SF

12th Floor, Ste 1210

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 2,096 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out -
Available Now

  • Lease rate does not include utilities, property expenses or building services
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1220 - 1,675 SF

12th Floor, Ste 1220

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 1,675 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Clinical space with great views throughout.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Can be combined with additional space(s) for up to 3,616 SF of adjacent space
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1230 - 1,941 SF

12th Floor, Ste 1230

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 1,941 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Partial Build-Out
Available Now

Spacious office/Medical suite with 1,941 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Partially Built-Out as Standard Office
  • Office intensive layout
  • Can be combined with additional space(s) for up to 3,616 SF of adjacent space
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1300 - 8,232 SF

13th Floor, Ste 1300

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 8,232 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available 90 Days

  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1400 - 8,604 SF

14th Floor, Ste 1400

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 8,604 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Full floor opportunity; available Fall 2024.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Office intensive layout
  • Can be combined with additional space(s) for up to 17,185 SF of adjacent space
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1500 - 8,581 SF

15th Floor, Ste 1500

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 8,581 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

Full floor opportunity; available Fall 2024.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Office intensive layout
  • Can be combined with additional space(s) for up to 17,185 SF of adjacent space
1 of 1
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1600 - 8,604 SF

16th Floor, Ste 1600

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 8,604 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Office intensive layout
  • Space is in Excellent Condition
1 of 1
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1730 - 2,912 SF

17th Floor, Ste 1730

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 2,912 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available Now

  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 5,007 SF of adjacent space
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4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
4126 Southwest Freeway - Suite 1750 - 2,095 SF

17th Floor, Ste 1750

4126 Southwest Fwy, Houston, TX for lease Floor Plan- Image 1 of 1
Floor Plan
Size 2,095 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Partial Build-Out
Available Now

Spacious office/Medical suite with 2,095 sqft available.

  • Lease rate does not include utilities, property expenses or building services
  • Partially Built-Out as Standard Office
  • Office intensive layout
  • Can be combined with additional space(s) for up to 5,007 SF of adjacent space

Property Overview

River Oaks Medical Tower is a 17-story, approximately 140,000-square-foot medical office building offering a contemporary approach to care in one of Houston’s most prestigious and well-connected neighborhoods. Positioned at the intersection of affluence, accessibility, and healthcare demand, the property has been thoughtfully reimagined to support the evolving needs of modern medical practices and their patients. Driven by Altera’s vision for redevelopment, the building features a reimagined first-floor lobby, refreshed elevator banks, an enhanced patient arrival experience, and a new rear entryway complemented by an onsite pocket park. These improvements prioritize seamless access, patient comfort, and an elevated sense of arrival while reinforcing the building’s position as a premier medical destination. The property offers unmatched visibility and immediate connectivity to Houston’s key inner-loop neighborhoods, including River Oaks, West University, Bellaire, Uptown, Midtown, Downtown, the Galleria, Rice Village, the Heights, and the Texas Medical Center—all within a short drive. This central location enables providers to draw from a broad and highly desirable patient base while maintaining convenience for physicians and staff. Within a three-mile radius, River Oaks Medical Tower benefits from a dense and affluent demographic profile, including a high daytime population, strong healthcare utilization, and a predominately privately insured patient mix. These fundamentals support long-term practice sustainability and make the building particularly attractive to specialty, outpatient, and boutique healthcare providers seeking proximity to demand rather than hospital campuses. To further enhance the tenant experience, the building offers move-in-ready spec suites ranging from approximately 2,500 to 3,000 square feet provide turnkey solutions for practices seeking immediate occupancy without construction delays. River Oaks Medical Tower stands as a differentiated medical office environment where care and wellness converge, combining location, design, and demographics to serve the next generation of healthcare delivery.

  • Property Manager on Site
  • Security System
  • Signage
  • On-Site Security Staff

Property Facts

Building Type
Office
Year Built/Renovated
1979/2013
LoopNet Rating
4 Star
Building Height
17 Stories
Building Size
140,012 SF
Building Class
A
Typical Floor Size
8,236 SF
Unfinished Ceiling Height
11’
Parking
Surface Parking
960 Covered Parking Spaces
Reserved Parking at $68 CAD/month

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 9th
  • MIA Plastic Surgery
  • Health Care and Social Assistance
  • Multiple
  • Performance Pain & Sports Medicine
  • Health Care and Social Assistance
  • 1st
  • Summit Ambulatory Surgery Center
  • Health Care and Social Assistance
  • 5th
  • Veteran Evaluation Services
  • Health Care and Social Assistance

Attachments

Suite 230
Suite 1220
Suite 1230
Suite 1400
Suite 1500
Suite 1600
Suite 820
Suite 1020
Suite 1000
Suite 400
Suite 600E
Suite 600G
Suite 700
Suite 710
Suite 730
Suite 200
Suite 330
Suite 300
Suite 310
Suite 320
River Oaks Medical Tower Leasing Brochure
Suite 1750

Links

1 1
Moderately walkable
60/100
Exceptionally drivable
100/100
Some public transit
40/100
Source: Local Logic®
(713) 231-1588

Still interested?

Contact the brokers for more information about this property

Contacts

  • Listing ID: 33508911

  • Date on Market: 2026-03-11

  • Last Updated:

  • Address: 4126 Southwest Fwy, Houston, TX 77027

The Afton Oaks Office/Medical Property at 4126 Southwest Fwy, Houston, TX 77027 is currently available. Contact Transwestern Real Estate Services for more information.

OFFICE PROPERTIES IN NEARBY NEIGHBORHOODS

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4126 Southwest Fwy, Houston, TX for lease Primary Photo- Image 1 of 6
Primary Photo
4126 Southwest Fwy, Houston, TX for lease Building Photo- Image 2 of 6
Building Photo
4126 Southwest Fwy, Houston, TX for lease Interior Photo- Image 3 of 6
Interior Photo
4126 Southwest Fwy, Houston, TX for lease Interior Photo- Image 4 of 6
Interior Photo
4126 Southwest Fwy, Houston, TX for lease Interior Photo- Image 5 of 6
River Oaks Medical Tower Front Entry 4.2.26
1 of 1
River Oaks Medical Tower | 4126 Southwest Fwy
(713) 231-1588 x

River Oaks Medical Tower | 4126 Southwest Fwy

Christian Connell
(713) 231-1588

Justin Brasell
(832) 646-4284

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