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@4240 4240 Duncan Ave 1,698 SF of 5-Star Retail Space Available in Saint Louis, MO 63110

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ALL AVAILABLE SPACE(1)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 1st Floor
  • 1,698 SF
  • 3-5 Years
  • $25.11 CAD/SF/YR $2.09 CAD/SF/MO $42,643 CAD/YR $3,554 CAD/MO
  • Retail
  • -
  • 2026-03-01

Class A café space available in the heart of St. Louis’ Cortex Innovation District, the region’s leading hub for technology, research, and entrepreneurship. This beautifully designed 1,698 SF space is ideal for a coffee shop, bakery, or quick-service café seeking a prominent, walkable location in a neighborhood surrounded by thousands of daily professionals and students. Enjoy a modern open layout, high ceilings, large windows, and natural light that creates a warm and inviting atmosphere. Outdoor seating and signage opportunities further enhance exposure and curb appeal. Located in the Cortex Innovation District, this property sits within a 200-acre, 42-building community featuring 54 companies and over 5,700 employees. Nearby tenants include BJC Healthcare, Washington University School of Medicine, Vir Biotechnology, and AB Mauri Foods. The site offers easy access to Forest Park Avenue, I-64, Brickline Greenway, and the MetroLink Station, ensuring strong pedestrian traffic and convenient connectivity to downtown St. Louis and the Central West End.

  • Listed rate may not include certain utilities, building services and property expenses
  • Open layout, high ceilings and large windows
  • Community featuring 54 companies, 5,700 employees
  • Very Walkable (74)
  • Cortex Innovation District
  • Easy access to Forest Park, I-64, Brickline, Metro
Space Size Term Rental Rate Space Use Condition Available
1st Floor 1,698 SF 3-5 Years $25.11 CAD/SF/YR $2.09 CAD/SF/MO $42,643 CAD/YR $3,554 CAD/MO Retail - 2026-03-01

1st Floor

Size
1,698 SF
Term
3-5 Years
Rental Rate
$25.11 CAD/SF/YR $2.09 CAD/SF/MO $42,643 CAD/YR $3,554 CAD/MO
Space Use
Retail
Condition
-
Available
2026-03-01

1st Floor

Size 1,698 SF
Term 3-5 Years
Rental Rate $25.11 CAD/SF/YR
Space Use Retail
Condition -
Available 2026-03-01

Class A café space available in the heart of St. Louis’ Cortex Innovation District, the region’s leading hub for technology, research, and entrepreneurship. This beautifully designed 1,698 SF space is ideal for a coffee shop, bakery, or quick-service café seeking a prominent, walkable location in a neighborhood surrounded by thousands of daily professionals and students. Enjoy a modern open layout, high ceilings, large windows, and natural light that creates a warm and inviting atmosphere. Outdoor seating and signage opportunities further enhance exposure and curb appeal. Located in the Cortex Innovation District, this property sits within a 200-acre, 42-building community featuring 54 companies and over 5,700 employees. Nearby tenants include BJC Healthcare, Washington University School of Medicine, Vir Biotechnology, and AB Mauri Foods. The site offers easy access to Forest Park Avenue, I-64, Brickline Greenway, and the MetroLink Station, ensuring strong pedestrian traffic and convenient connectivity to downtown St. Louis and the Central West End.

  • Listed rate may not include certain utilities, building services and property expenses
  • Very Walkable (74)
  • Open layout, high ceilings and large windows
  • Cortex Innovation District
  • Community featuring 54 companies, 5,700 employees
  • Easy access to Forest Park, I-64, Brickline, Metro

SELECT TENANTS

  • FLOOR
  • TENANT NAME
  • INDUSTRY
  • 1st
  • AB Mauri Foods Inc
  • Retailer
  • 2nd
  • Cortex Innovation Community
  • Real Estate
  • 1st
  • Park Avenue Coffee
  • Accommodation and Food Services
  • 3rd
  • Vir Biotechnology, Inc.
  • Professional, Scientific, and Technical Services
  • 1st
  • WUSTL Office of Technology Management
  • Educational Services

PROPERTY FACTS

Building Type
Office
Year Built
2014
LoopNet Rating
5 Star
Building Height
3 Stories
Building Size
202,551 SF
Building Class
A
Typical Floor Size
67,517 SF

FEATURES AND AMENITIES

  • Atrium
  • Commuter Rail
  • Courtyard
  • Fitness Center
  • Metro/Subway
  • Restaurant
  • Central Heating
  • Air Conditioning
Walk Score®
Very Walkable (70)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures the walkability of any address.
Transit Score® measures access to public transit.
Bike Score® measures bikeability of a location.
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures the walkability
of any address. Transit Score®
measures access to public transit. Bike Score®
measures bikeability of a location.®

NEARBY MAJOR RETAILERS

Lion's Choice
Starbucks
U.S. Bank
Five Guys
Rent-A-Center
Schnucks
Simmons Bank
Commerce Bank
Planet Fitness
Orangetheory Fitness
  • Listing ID: 38307350

  • Date on Market: 2025-11-03

  • Last Updated:

  • Address: 4240 Duncan Ave, Saint Louis, MO 63110

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