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Highlights

  • Excellent accessibility to Hwy 75 and Sam Rayburn Tollway
  • Affluent payor mix with exceptional projected population growth
  • Adjacent to Medical City McKinney Campus – Undergoing an extensive Expansion
  • Ample surface parking

All Available Spaces(6)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 1st Floor, Ste C-2
  • 3,158 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • 1st Floor, Ste Suite C-1
  • 2,173 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • 1st Floor, Ste Suite D
  • 2,455 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
  • 1st Floor, Ste Suite E
  • 4,374 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • 2027-06-01
  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space
  • Fully Built-Out as Standard Office
  • Space is in Excellent Condition
  • 1st Floor, Ste Suite F
  • 4,212 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space
  • Fully Built-Out as Professional Services Office
  • Space is in Excellent Condition
  • 1st Floor, Ste Suite H
  • 1,683 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition
Space Size Term Rental Rate Space Use Build-Out Available
1st Floor, Ste C-2 3,158 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out 2027-06-01
1st Floor, Ste Suite C-1 2,173 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out 2027-06-01
1st Floor, Ste Suite D 2,455 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out 2027-06-01
1st Floor, Ste Suite E 4,374 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out 2027-06-01
1st Floor, Ste Suite F 4,212 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out 2027-06-01
1st Floor, Ste Suite H 1,683 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out 2027-06-01

1st Floor, Ste C-2

Size
3,158 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
2027-06-01

1st Floor, Ste Suite C-1

Size
2,173 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
2027-06-01

1st Floor, Ste Suite D

Size
2,455 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
2027-06-01

1st Floor, Ste Suite E

Size
4,374 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
Full Build-Out
Available
2027-06-01

1st Floor, Ste Suite F

Size
4,212 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
Full Build-Out
Available
2027-06-01

1st Floor, Ste Suite H

Size
1,683 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Build-Out
Full Build-Out
Available
2027-06-01

1st Floor, Ste C-2

Size 3,158 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space

1st Floor, Ste Suite C-1

Size 2,173 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space

1st Floor, Ste Suite D

Size 2,455 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space

1st Floor, Ste Suite E

Size 4,374 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Build-Out Full Build-Out
Available 2027-06-01

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space

1st Floor, Ste Suite F

Size 4,212 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Build-Out Full Build-Out
Available 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Professional Services Office
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space

1st Floor, Ste Suite H

Size 1,683 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Build-Out Full Build-Out
Available 2027-06-01

McKinney Medical Building is a 33,592-square-foot Class A medical outpatient building (“MOB”) positioned directly across from 311bed Medical City McKinney, one of Collin County’s largest and most advanced hospital campuses. The Medical City McKinney hospital campus is undergoing significant expansion, including a new $17 million women’s hospital (2023), a $50 million, five-story, 124,500-square-foot medical building (2025), a new west-campus parking lot adding 750+ spaces, and an ongoing $142 million, twostory east tower project that will increase medical-surgical, stepdown and intensive care units.

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 18,055 SF of adjacent space

Property Overview

McKinney Medical Building offers premier medical office space for lease in a highly visible location across from Medical City McKinney. The property features a healthcare-focused design, including a covered patient drop-off/pick-up area, strong parking ratios, and controlled 24-hour access. Available suites range from 1,683 SF to 18,055 SF, accommodating a variety of medical practices. The building is strategically located near U.S. Highway 75 and Sam Rayburn Tollway, providing excellent accessibility for patients and staff. Tenants benefit from proximity to a major hospital campus undergoing significant expansion, ensuring continued growth in patient traffic and healthcare demand. This location positions medical providers to serve a growing and affluent population in one of the fastest-growing regions in the Dallas–Fort Worth metro area.

  • 24 Hour Access
  • Controlled Access
  • Central Heating
  • Air Conditioning

Property Facts

Building Type
Office
Year Built
2006
Building Height
1 Story
Building Size
33,990 SF
Building Class
B
Typical Floor Size
33,990 SF
Parking
168 Surface Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 1st
  • DaVita Kidney Care
  • Health Care and Social Assistance
  • 1st
  • McKinneyCare Pharmacy and Compounding
  • Retailer
  • 1st
  • Most/DFW
  • Health Care and Social Assistance
Fairly walkable
40/100
Exceptionally drivable
100/100
Somewhat bikeable
30/100
  • Listing ID: 39714458

  • Date on Market: 2026-03-30

  • Last Updated:

  • Address: 4601 Medical Center Dr, McKinney, TX 75069

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