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One Market Exchange 515 E Main St 5,873 - 42,899 SF of 4-Star Office/Medical Space Available in Columbus, OH 43215



HIGHLIGHTS
- Medical and Creative Office Space
- Newly renovated lobby, restrooms, and elevators
- Exposed ceilings and concrete floors
- Located downtown in the Market Exchange District near Nationwide Children’s Hospital and Grant Medical Center
- Mix of private office and open collaboration space
ALL AVAILABLE SPACES(4)
Display Rental Rate as
- SPACE
- SIZE
- TERM
- RENTAL RATE
- SPACE USE
- CONDITION
- AVAILABLE
https://my.matterport.com/show/?m=p1VBap893FB
- Lease rate does not include utilities, property expenses or building services
- Mostly Open Floor Plan Layout
- Central Air and Heating
- Wheelchair Accessible
- Exposed ceilings and concrete floors
- Fully Built-Out as Standard Office
- Space is in Excellent Condition
- Private Restrooms
- Mix of private office and open collaboration space
- Signage opportunity
Located in the heart of downtown Columbus, 515 E Main Street offers a rare blend of medical and creative office space within a professionally managed, five-story building. With newly renovated lobbies, restrooms, and elevators, the property delivers a polished first impression and modern functionality. Tenants benefit from exposed ceilings, concrete floors, and a mix of private offices and open collaboration zones—ideal for both healthcare providers and creative professionals. The building’s strategic location places it within walking distance of premier dining, fitness, and retail options, including Katzinger’s Delicatessen, Starbucks, Kroger, and CVS. On-site free parking and proximity to major highways enhance accessibility for staff and clients alike. Healthcare tenants will appreciate the proximity to Grant Medical Center and Nationwide Children’s Hospital, while creative users will find inspiration in the vibrant urban surroundings. With market-leading tenant improvement packages and architectural space planning support, 515 E Main Street is designed to accommodate a wide range of professional needs. Whether you're seeking a full-floor presence or a tailored suite, this property offers flexibility, visibility, and a dynamic downtown experience. https://my.matterport.com/show/?m=FNmx11dAhYj
- Fully Built-Out as Standard Office
- Space is in Excellent Condition
- Free on-site parking and walkable access to dining
- Open Floor Plan Layout
- Central Air and Heating
- Signage opportunities available
Located in the heart of downtown Columbus, 515 E Main Street offers a rare blend of medical and creative office space within a professionally managed, five-story building. With newly renovated lobbies, restrooms, and elevators, the property delivers a polished first impression and modern functionality. Tenants benefit from exposed ceilings, concrete floors, and a mix of private offices and open collaboration zones—ideal for both healthcare providers and creative professionals. The building’s strategic location places it within walking distance of premier dining, fitness, and retail options, including Katzinger’s Delicatessen, Starbucks, Kroger, and CVS. On-site free parking and proximity to major highways enhance accessibility for staff and clients alike. Healthcare tenants will appreciate the proximity to Grant Medical Center and Nationwide Children’s Hospital, while creative users will find inspiration in the vibrant urban surroundings. With market-leading tenant improvement packages and architectural space planning support, 515 E Main Street is designed to accommodate a wide range of professional needs. Whether you're seeking a full-floor presence or a tailored suite, this property offers flexibility, visibility, and a dynamic downtown experience. https://my.matterport.com/show/?m=ikZbEV6222C
- Fully Built-Out as Standard Office
- Space is in Excellent Condition
- Free on-site parking and walkable access to dining
- Mostly Open Floor Plan Layout
- Central Air and Heating
- Signage opportunities available
https://my.matterport.com/show/?m=PD5XdAYjZnW
- Lease rate does not include utilities, property expenses or building services
- Space is in Excellent Condition
- Private Restrooms
- Mix of private office and open collaboration space
- Signage opportunity
- Fully Built-Out as Standard Office
- Central Air and Heating
- Wheelchair Accessible
- Exposed ceilings and concrete floors
- Full 5th floor available
| Space | Size | Term | Rental Rate | Space Use | Condition | Available |
| 2nd Floor | 14,205 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | Now |
| 3rd Floor | 6,851 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | 2026-07-01 |
| 4th Floor | 15,970 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | 2026-07-01 |
| 5th Floor, Ste 500 | 5,873 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office/Medical | Full Build-Out | Now |
2nd Floor
| Size |
| 14,205 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Condition |
| Full Build-Out |
| Available |
| Now |
3rd Floor
| Size |
| 6,851 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Condition |
| Full Build-Out |
| Available |
| 2026-07-01 |
4th Floor
| Size |
| 15,970 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Condition |
| Full Build-Out |
| Available |
| 2026-07-01 |
5th Floor, Ste 500
| Size |
| 5,873 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office/Medical |
| Condition |
| Full Build-Out |
| Available |
| Now |
2nd Floor
| Size | 14,205 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Condition | Full Build-Out |
| Available | Now |
https://my.matterport.com/show/?m=p1VBap893FB
- Lease rate does not include utilities, property expenses or building services
- Fully Built-Out as Standard Office
- Mostly Open Floor Plan Layout
- Space is in Excellent Condition
- Central Air and Heating
- Private Restrooms
- Wheelchair Accessible
- Mix of private office and open collaboration space
- Exposed ceilings and concrete floors
- Signage opportunity
3rd Floor
| Size | 6,851 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Condition | Full Build-Out |
| Available | 2026-07-01 |
Located in the heart of downtown Columbus, 515 E Main Street offers a rare blend of medical and creative office space within a professionally managed, five-story building. With newly renovated lobbies, restrooms, and elevators, the property delivers a polished first impression and modern functionality. Tenants benefit from exposed ceilings, concrete floors, and a mix of private offices and open collaboration zones—ideal for both healthcare providers and creative professionals. The building’s strategic location places it within walking distance of premier dining, fitness, and retail options, including Katzinger’s Delicatessen, Starbucks, Kroger, and CVS. On-site free parking and proximity to major highways enhance accessibility for staff and clients alike. Healthcare tenants will appreciate the proximity to Grant Medical Center and Nationwide Children’s Hospital, while creative users will find inspiration in the vibrant urban surroundings. With market-leading tenant improvement packages and architectural space planning support, 515 E Main Street is designed to accommodate a wide range of professional needs. Whether you're seeking a full-floor presence or a tailored suite, this property offers flexibility, visibility, and a dynamic downtown experience. https://my.matterport.com/show/?m=FNmx11dAhYj
- Fully Built-Out as Standard Office
- Open Floor Plan Layout
- Space is in Excellent Condition
- Central Air and Heating
- Free on-site parking and walkable access to dining
- Signage opportunities available
4th Floor
| Size | 15,970 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Condition | Full Build-Out |
| Available | 2026-07-01 |
Located in the heart of downtown Columbus, 515 E Main Street offers a rare blend of medical and creative office space within a professionally managed, five-story building. With newly renovated lobbies, restrooms, and elevators, the property delivers a polished first impression and modern functionality. Tenants benefit from exposed ceilings, concrete floors, and a mix of private offices and open collaboration zones—ideal for both healthcare providers and creative professionals. The building’s strategic location places it within walking distance of premier dining, fitness, and retail options, including Katzinger’s Delicatessen, Starbucks, Kroger, and CVS. On-site free parking and proximity to major highways enhance accessibility for staff and clients alike. Healthcare tenants will appreciate the proximity to Grant Medical Center and Nationwide Children’s Hospital, while creative users will find inspiration in the vibrant urban surroundings. With market-leading tenant improvement packages and architectural space planning support, 515 E Main Street is designed to accommodate a wide range of professional needs. Whether you're seeking a full-floor presence or a tailored suite, this property offers flexibility, visibility, and a dynamic downtown experience. https://my.matterport.com/show/?m=ikZbEV6222C
- Fully Built-Out as Standard Office
- Mostly Open Floor Plan Layout
- Space is in Excellent Condition
- Central Air and Heating
- Free on-site parking and walkable access to dining
- Signage opportunities available
5th Floor, Ste 500
| Size | 5,873 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office/Medical |
| Condition | Full Build-Out |
| Available | Now |
https://my.matterport.com/show/?m=PD5XdAYjZnW
- Lease rate does not include utilities, property expenses or building services
- Fully Built-Out as Standard Office
- Space is in Excellent Condition
- Central Air and Heating
- Private Restrooms
- Wheelchair Accessible
- Mix of private office and open collaboration space
- Exposed ceilings and concrete floors
- Signage opportunity
- Full 5th floor available
PROPERTY OVERVIEW
1 Market Exchange is a modern 56,856 SF five-story office building that has desirable professional and creative offices suites and a full floor available. The interior spaces contain concrete floors, exposed ceilings and ductwork, natural light and a mix of open and private office space. The building is a well-known landmark in the heart of the Market Exchange district in downtown Columbus walkable to nearby amenities and allows for convenient access to all major freeways. Free surface parking is available on site and adjacent to the building in a private parking lot.
- Controlled Access
- Security System
PROPERTY FACTS
SELECT TENANTS
- FLOOR
- TENANT NAME
- Multiple
- DesignGroup
- 1st
- Hanger Prosthetics & Orthotics, Inc
- 1st
- NECCO
- 3rd
- OhioGuidestone
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One Market Exchange | 515 E Main St
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