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Mission Center Office Pk 5333 Mission Center Rd 2,256 - 34,525 SF of Office/Medical Space Available in San Diego, CA 92108

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HIGHLIGHTS

  • Updated outdoor atriums with casual seating and meeting spaces
  • Exclusive outdoor patio areas for select ground floor spaces
  • EV charging stations
  • On-site fitness room with showers
  • Renovated building plaza
  • Common area Wi-Fi

SPACE AVAILABILITY (7)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • RENT TYPE
  • 1st Floor, Ste 105
  • 6,653 SF
  • Negotiable
  • $51.09 CAD/SF/YR $4.26 CAD/SF/MO $339,906 CAD/YR $28,326 CAD/MO
  • Plus All Utilities
5333 Mission Center Rd - 1st Floor - Ste 105
Space Use
Office/Medical
Condition
Partial Build-Out
Availability
Now

Reception, 11 private offices, 2 large conference rooms, break room, IT and large open area.

  • Listed lease rate plus proportional share of utilities
  • Partially Built-Out as Professional Services Office
  • Mostly Open Floor Plan Layout
  • Fits 17 - 54 People
  • 11 Private Offices
  • 2 Conference Rooms
  • Central Air Conditioning
  • 2nd Floor, Ste 200
  • 5,213 SF
  • Negotiable
  • $51.09 CAD/SF/YR $4.26 CAD/SF/MO $266,336 CAD/YR $22,195 CAD/MO
  • Plus All Utilities
5333 Mission Center Rd - 2nd Floor - Ste 200
Space Use
Office/Medical
Condition
Partial Build-Out
Availability
Now

Reception, 6 private offices, training room, break room, IT and storage.

  • Listed lease rate plus proportional share of utilities
  • Partially Built-Out as Standard Office
  • Fits 14 - 42 People
  • 6 Private Offices
  • Can be combined with additional space(s) for up to 14,822 SF of adjacent space
  • Central Air Conditioning
  • 2nd Floor, Ste 220
  • 5,649 SF
  • Negotiable
  • $51.09 CAD/SF/YR $4.26 CAD/SF/MO $288,611 CAD/YR $24,051 CAD/MO
  • Plus All Utilities
5333 Mission Center Rd - 2nd Floor - Ste 220
Space Use
Office/Medical
Condition
Partial Build-Out
Availability
2026-05-01

Reception, 11 private offices, conference room, open break area. Contiguous with suites 200 & 240 for up to 14,822 RSF.

  • Listed lease rate plus proportional share of utilities
  • Partially Built-Out as Standard Office
  • Fits 15 - 46 People
  • 11 Private Offices
  • 1 Conference Room
  • Can be combined with additional space(s) for up to 14,822 SF of adjacent space
  • Reception Area
  • 2nd Floor, Ste 224
  • 3,295 SF
  • Negotiable
  • $51.09 CAD/SF/YR $4.26 CAD/SF/MO $168,344 CAD/YR $14,029 CAD/MO
  • Plus All Utilities
5353 Mission Center Rd - 2nd Floor - Ste 224
Space Use
Office/Medical
Condition
Full Build-Out
Availability
2026-02-01

Available 2/1/26. Reception, 10 private offices, break room. Contiguous with suite 222 for up to 5,157 RSF.

  • Listed lease rate plus proportional share of utilities
  • Fully Built-Out as Standard Office
  • Fits 9 - 27 People
  • 10 Private Offices
  • 2nd Floor, Ste 240
  • 3,960 SF
  • Negotiable
  • $51.09 CAD/SF/YR $4.26 CAD/SF/MO $202,319 CAD/YR $16,860 CAD/MO
  • Plus All Utilities
5333 Mission Center Rd - 2nd Floor - Ste 240
Space Use
Office/Medical
Condition
Full Build-Out
Availability
Now

Reception, 6 private offices, breakroom, conference room and open office area. Contiguous with suites 200 & 220 for up to 14,822 RSF

  • Listed lease rate plus proportional share of utilities
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 10 - 32 People
  • 6 Private Offices
  • 1 Conference Room
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 14,822 SF of adjacent space
  • Reception Area
  • Central Air Conditioning
  • 3rd Floor, Ste 300
  • 7,499 SF
  • Negotiable
  • $51.09 CAD/SF/YR $4.26 CAD/SF/MO $383,129 CAD/YR $31,927 CAD/MO
  • Plus All Utilities
5333 Mission Center Rd - 3rd Floor - Ste 300
Space Use
Office/Medical
Condition
Full Build-Out
Availability
2026-03-01

12 private offices, large conference room, break room, IT, and storage rooms.

  • Listed lease rate plus proportional share of utilities
  • Fully Built-Out as Standard Office
  • Fits 19 - 60 People
  • 12 Private Offices
  • 1 Conference Room
  • 3rd Floor, Ste 356
  • 2,256 SF
  • Negotiable
  • $51.09 CAD/SF/YR $4.26 CAD/SF/MO $115,261 CAD/YR $9,605 CAD/MO
  • Plus All Utilities
5333 Mission Center Rd - 3rd Floor - Ste 356
Space Use
Office/Medical
Condition
Full Build-Out
Availability
Now

Reception. Open area, 4 offices and kitchenette.

  • Listed lease rate plus proportional share of utilities
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 6 - 19 People
  • 4 Private Offices
  • Reception Area
Space Size Term Rental Rate Rent Type
1st Floor, Ste 105 6,653 SF Negotiable $51.09 CAD/SF/YR $4.26 CAD/SF/MO $339,906 CAD/YR $28,326 CAD/MO Plus All Utilities
2nd Floor, Ste 200 5,213 SF Negotiable $51.09 CAD/SF/YR $4.26 CAD/SF/MO $266,336 CAD/YR $22,195 CAD/MO Plus All Utilities
2nd Floor, Ste 220 5,649 SF Negotiable $51.09 CAD/SF/YR $4.26 CAD/SF/MO $288,611 CAD/YR $24,051 CAD/MO Plus All Utilities
2nd Floor, Ste 224 3,295 SF Negotiable $51.09 CAD/SF/YR $4.26 CAD/SF/MO $168,344 CAD/YR $14,029 CAD/MO Plus All Utilities
2nd Floor, Ste 240 3,960 SF Negotiable $51.09 CAD/SF/YR $4.26 CAD/SF/MO $202,319 CAD/YR $16,860 CAD/MO Plus All Utilities
3rd Floor, Ste 300 7,499 SF Negotiable $51.09 CAD/SF/YR $4.26 CAD/SF/MO $383,129 CAD/YR $31,927 CAD/MO Plus All Utilities
3rd Floor, Ste 356 2,256 SF Negotiable $51.09 CAD/SF/YR $4.26 CAD/SF/MO $115,261 CAD/YR $9,605 CAD/MO Plus All Utilities

5333 Mission Center Rd - 1st Floor - Ste 105

Size
6,653 SF
Term
Negotiable
Rental Rate
$51.09 CAD/SF/YR $4.26 CAD/SF/MO $339,906 CAD/YR $28,326 CAD/MO
Rent Type
Plus All Utilities
Space Use
Office/Medical
Condition
Partial Build-Out
Availability
Now

Reception, 11 private offices, 2 large conference rooms, break room, IT and large open area.

  • Listed lease rate plus proportional share of utilities
  • Partially Built-Out as Professional Services Office
  • Mostly Open Floor Plan Layout
  • Fits 17 - 54 People
  • 11 Private Offices
  • 2 Conference Rooms
  • Central Air Conditioning

5333 Mission Center Rd - 2nd Floor - Ste 200

Size
5,213 SF
Term
Negotiable
Rental Rate
$51.09 CAD/SF/YR $4.26 CAD/SF/MO $266,336 CAD/YR $22,195 CAD/MO
Rent Type
Plus All Utilities
Space Use
Office/Medical
Condition
Partial Build-Out
Availability
Now

Reception, 6 private offices, training room, break room, IT and storage.

  • Listed lease rate plus proportional share of utilities
  • Partially Built-Out as Standard Office
  • Fits 14 - 42 People
  • 6 Private Offices
  • Can be combined with additional space(s) for up to 14,822 SF of adjacent space
  • Central Air Conditioning

5333 Mission Center Rd - 2nd Floor - Ste 220

Size
5,649 SF
Term
Negotiable
Rental Rate
$51.09 CAD/SF/YR $4.26 CAD/SF/MO $288,611 CAD/YR $24,051 CAD/MO
Rent Type
Plus All Utilities
Space Use
Office/Medical
Condition
Partial Build-Out
Availability
2026-05-01

Reception, 11 private offices, conference room, open break area. Contiguous with suites 200 & 240 for up to 14,822 RSF.

  • Listed lease rate plus proportional share of utilities
  • Partially Built-Out as Standard Office
  • Fits 15 - 46 People
  • 11 Private Offices
  • 1 Conference Room
  • Can be combined with additional space(s) for up to 14,822 SF of adjacent space
  • Reception Area

5353 Mission Center Rd - 2nd Floor - Ste 224

Size
3,295 SF
Term
Negotiable
Rental Rate
$51.09 CAD/SF/YR $4.26 CAD/SF/MO $168,344 CAD/YR $14,029 CAD/MO
Rent Type
Plus All Utilities
Space Use
Office/Medical
Condition
Full Build-Out
Availability
2026-02-01

Available 2/1/26. Reception, 10 private offices, break room. Contiguous with suite 222 for up to 5,157 RSF.

  • Listed lease rate plus proportional share of utilities
  • Fully Built-Out as Standard Office
  • Fits 9 - 27 People
  • 10 Private Offices

5333 Mission Center Rd - 2nd Floor - Ste 240

Size
3,960 SF
Term
Negotiable
Rental Rate
$51.09 CAD/SF/YR $4.26 CAD/SF/MO $202,319 CAD/YR $16,860 CAD/MO
Rent Type
Plus All Utilities
Space Use
Office/Medical
Condition
Full Build-Out
Availability
Now

Reception, 6 private offices, breakroom, conference room and open office area. Contiguous with suites 200 & 220 for up to 14,822 RSF

  • Listed lease rate plus proportional share of utilities
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 10 - 32 People
  • 6 Private Offices
  • 1 Conference Room
  • Space is in Excellent Condition
  • Can be combined with additional space(s) for up to 14,822 SF of adjacent space
  • Reception Area
  • Central Air Conditioning

5333 Mission Center Rd - 3rd Floor - Ste 300

Size
7,499 SF
Term
Negotiable
Rental Rate
$51.09 CAD/SF/YR $4.26 CAD/SF/MO $383,129 CAD/YR $31,927 CAD/MO
Rent Type
Plus All Utilities
Space Use
Office/Medical
Condition
Full Build-Out
Availability
2026-03-01

12 private offices, large conference room, break room, IT, and storage rooms.

  • Listed lease rate plus proportional share of utilities
  • Fully Built-Out as Standard Office
  • Fits 19 - 60 People
  • 12 Private Offices
  • 1 Conference Room

5333 Mission Center Rd - 3rd Floor - Ste 356

Size
2,256 SF
Term
Negotiable
Rental Rate
$51.09 CAD/SF/YR $4.26 CAD/SF/MO $115,261 CAD/YR $9,605 CAD/MO
Rent Type
Plus All Utilities
Space Use
Office/Medical
Condition
Full Build-Out
Availability
Now

Reception. Open area, 4 offices and kitchenette.

  • Listed lease rate plus proportional share of utilities
  • Fully Built-Out as Standard Office
  • Mostly Open Floor Plan Layout
  • Fits 6 - 19 People
  • 4 Private Offices
  • Reception Area

Rent Types


The rent amount and type that the tenant (lessee) will be responsible to pay to the landlord (lessor) throughout the lease term is negotiated prior to both parties signing a lease agreement. The rent type will vary depending upon the services provided. For example, triple net rents are typically lower than full service rents due to additional expenses the tenant is required to pay in addition to the base rent. Contact the listing broker for a full understanding of any associated costs or additional expenses for each rent type.

1. Full Service: A rental rate that includes normal building standard services as provided by the landlord within a base year rental.

2. Double Net (NN): Tenant pays for only two of the building expenses; the landlord and tenant determine the specific expenses prior to signing the lease agreement.

3. Triple Net (NNN): A lease in which the tenant is responsible for all expenses associated with their proportional share of occupancy of the building.

4. Modified Gross: Modified Gross is a general type of lease rate where typically the tenant will be responsible for their proportional share of one or more of the expenses. The landlord will pay the remaining expenses. See the below list of common Modified Gross rental rate structures: 4. Plus All Utilities: A type of Modified Gross Lease where the tenant is responsible for their proportional share of utilities in addition to the rent. 4. Plus Cleaning: A type of Modified Gross Lease where the tenant is responsible for their proportional share of cleaning in addition to the rent. 4. Plus Electric: A type of Modified Gross Lease where the tenant is responsible for their proportional share of the electrical cost in addition to the rent. 4. Plus Electric & Cleaning: A type of Modified Gross Lease where the tenant is responsible for their proportional share of the electrical and cleaning cost in addition to the rent. 4. Plus Utilities and Char: A type of Modified Gross Lease where the tenant is responsible for their proportional share of the utilities and cleaning cost in addition to the rent. 4. Industrial Gross: A type of Modified Gross lease where the tenant pays one or more of the expenses in addition to the rent. The landlord and tenant determine these prior to signing the lease agreement.

5. Tenant Electric: The landlord pays for all services and the tenant is responsible for their usage of lights and electrical outlets in the space they occupy.

6. Negotiable or Upon Request: Used when the leasing contact does not provide the rent or service type.

7. TBD: To be determined; used for buildings for which no rent or service type is known, commonly utilized when the buildings are not yet built.

SELECT TENANTS AT MISSION CENTER OFFICE PK

  • TENANT
  • DESCRIPTION
  • US LOCATIONS
  • REACH
  • American Cancer Society
  • Health Care
  • 287
  • National
  • Blue Sky Network
  • -
  • 1
  • Regional
  • California Teachers Association
  • Other Services
  • 44
  • Local
  • Concentra
  • Health Care
  • 851
  • National
  • Haley & Aldrich
  • Other Services
  • 71
  • National
  • Sonata Healthcare
  • -
  • 1
  • Local
TENANT DESCRIPTION US LOCATIONS REACH
American Cancer Society Health Care 287 National
Blue Sky Network - 1 Regional
California Teachers Association Other Services 44 Local
Concentra Health Care 851 National
Haley & Aldrich Other Services 71 National
Sonata Healthcare - 1 Local

PROPERTY FACTS

Total Space Available 34,525 SF
Max. Contiguous 14,822 SF
Center Type Strip Center
Parking 343 Spaces
Center Properties 5
Gross Leasable Area 5,618 SF
Total Land Area 21.62 AC
Year Built 1974

ABOUT THE PROPERTY

Located in the heart of the dynamic Mission Valley region, the new Mission Center is being transformed to provide unique offerings to its tenants unlike anything else in the marketplace today.

  • Atrium
  • Bus Line
  • Courtyard
  • Restaurant
  • Signage
Bike Score®
Very Bikeable (72)
What is a Walk Score®, Transit Score® & Bike Score®?
Walk Score® measures the walkability of any address.
Transit Score® measures access to public transit.
Bike Score® measures bikeability of a location.
What is a Walk Score®
, Transit Score® & Bike Score?
Walk Score® measures the walkability
of any address. Transit Score®
measures access to public transit. Bike Score®
measures bikeability of a location.®

NEARBY MAJOR RETAILERS

Ralphs
Citi
U.S. Bank
California Fish Grill
Sammy's Woodfired Pizza
BJ's Restaurant & Brewhouse
Denny's
Everbowl
Flame Broiler
Bank of America
  • Listing ID: 24225925

  • Date on Market: 2025-10-29

  • Last Updated:

  • Address: 5333 Mission Center Rd, San Diego, CA 92108

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