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553 St Kilda Rd 7,922 - 69,330 SF of Office Space Available in Melbourne, VIC 3004

Highlights
- Prime Alfred Precinct location, providing unrivaled adjacency to leading medical and research organizations, including Alfred Health.
- Floorplates ranging from 735 m² to over 1,500 m², all offering excellent natural light and side-core efficiency.
- Direct pedestrian access to Alfred Hospital, ensuring safe and seamless connectivity for tenants and visitors.
- Abundant secure on-site parking available for staff and visitors.
All Available Spaces(5)
Display Rental Rate as
- Space
- Size
- Term
- Rental Rate
- Space Use
- Build-Out
- Available
The ground floor at 553 St Kilda Road offers 735.8 m² of prime office/showroom space with immediate street presence and direct access to the Alfred Medical Precinct from the rear entry. This versatile level can accommodate a mix of reception, client-facing areas, open-plan zones, or specialized consulting/health uses. Large glazing lines deliver strong natural light alongside excellent exposure to St Kilda Road’s active commercial corridor.
- Fits 20 - 62 People
- Direct pedestrian link to Alfred Hospital
- Secure on-site parking available
- 735.8 m² with highly visible street frontage
- Efficient open-plan layout
Level 1 provides a highly adaptable 1,090.7 m² floorplate, combining open-plan workspace capacity with enclosed meeting and executive zones. Its side-core design ensures excellent spatial efficiency and fitout options for collaborative workplaces or medical/research administration settings.
- Fits 30 - 91 People
- Expansive 1,090.7 m² tenancy
This generous floorplate is perfect for major corporate users or clinical research specialists requiring large-scale occupancy. Its 1,540.9 m² layout features clear spans and abundant light, facilitating open-plan work areas, laboratories, or hybrid design concepts.
- Fits 42 - 129 People
- 1,540.9 m² office tenancy
This generous floorplate is perfect for major corporate users or clinical research specialists requiring large-scale occupancy. Its 1,540.9 m² layout features clear spans and abundant light, facilitating open-plan work areas, laboratories, or hybrid design concepts.
- Fits 42 - 129 People
- 1,540.9 m² office tenancy
Level 4 provides 1,532 m² of exceptional office accommodation harnessing commanding views and a bright, elevated outlook. Designed for occupiers seeking a full-floor headquarters or flagship location, this tenancy accommodates sophisticated layouts while maintaining efficient open-plan capability.
- Fits 42 - 128 People
- 1,532 m² office tenancy
| Space | Size | Term | Rental Rate | Space Use | Build-Out | Available |
| Ground | 7,922 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office | - | Now |
| 1st Floor | 11,743 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office | - | Now |
| 2nd Floor | 16,587 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office | - | Now |
| 3rd Floor | 16,587 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office | - | Now |
| 4th Floor | 16,490 SF | Negotiable | Upon Request Upon Request Upon Request Upon Request | Office | - | Now |
Ground
| Size |
| 7,922 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office |
| Build-Out |
| - |
| Available |
| Now |
1st Floor
| Size |
| 11,743 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office |
| Build-Out |
| - |
| Available |
| Now |
2nd Floor
| Size |
| 16,587 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office |
| Build-Out |
| - |
| Available |
| Now |
3rd Floor
| Size |
| 16,587 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office |
| Build-Out |
| - |
| Available |
| Now |
4th Floor
| Size |
| 16,490 SF |
| Term |
| Negotiable |
| Rental Rate |
| Upon Request Upon Request Upon Request Upon Request |
| Space Use |
| Office |
| Build-Out |
| - |
| Available |
| Now |
Ground
| Size | 7,922 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office |
| Build-Out | - |
| Available | Now |
The ground floor at 553 St Kilda Road offers 735.8 m² of prime office/showroom space with immediate street presence and direct access to the Alfred Medical Precinct from the rear entry. This versatile level can accommodate a mix of reception, client-facing areas, open-plan zones, or specialized consulting/health uses. Large glazing lines deliver strong natural light alongside excellent exposure to St Kilda Road’s active commercial corridor.
- Fits 20 - 62 People
- 735.8 m² with highly visible street frontage
- Direct pedestrian link to Alfred Hospital
- Efficient open-plan layout
- Secure on-site parking available
1st Floor
| Size | 11,743 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office |
| Build-Out | - |
| Available | Now |
Level 1 provides a highly adaptable 1,090.7 m² floorplate, combining open-plan workspace capacity with enclosed meeting and executive zones. Its side-core design ensures excellent spatial efficiency and fitout options for collaborative workplaces or medical/research administration settings.
- Fits 30 - 91 People
- Expansive 1,090.7 m² tenancy
2nd Floor
| Size | 16,587 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office |
| Build-Out | - |
| Available | Now |
This generous floorplate is perfect for major corporate users or clinical research specialists requiring large-scale occupancy. Its 1,540.9 m² layout features clear spans and abundant light, facilitating open-plan work areas, laboratories, or hybrid design concepts.
- Fits 42 - 129 People
- 1,540.9 m² office tenancy
3rd Floor
| Size | 16,587 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office |
| Build-Out | - |
| Available | Now |
This generous floorplate is perfect for major corporate users or clinical research specialists requiring large-scale occupancy. Its 1,540.9 m² layout features clear spans and abundant light, facilitating open-plan work areas, laboratories, or hybrid design concepts.
- Fits 42 - 129 People
- 1,540.9 m² office tenancy
4th Floor
| Size | 16,490 SF |
| Term | Negotiable |
| Rental Rate | Upon Request |
| Space Use | Office |
| Build-Out | - |
| Available | Now |
Level 4 provides 1,532 m² of exceptional office accommodation harnessing commanding views and a bright, elevated outlook. Designed for occupiers seeking a full-floor headquarters or flagship location, this tenancy accommodates sophisticated layouts while maintaining efficient open-plan capability.
- Fits 42 - 128 People
- 1,532 m² office tenancy
Property Overview
Positioned in the heart of the prestigious Alfred Medical Precinct, 553 St Kilda Road presents a rare leasing opportunity offering 6,440 m² of premium office accommodation. Available for the first time in more than a decade, this landmark building provides occupiers with direct pedestrian access to the Alfred Hospital campus via a secure rear entry, supporting tenants in the health, research, or allied services sectors while appealing equally to corporate users seeking an elite address. The property features large side-core floorplates across five levels, delivering superior efficiency, high natural light penetration, and flexibility for open-plan or bespoke fitout configurations. Each floor benefits from excellent ceiling heights and professional-grade services, creating a significant advantage for businesses prioritizing workforce comfort and operational flow. The building also offers secure on-site parking, a 5-Star NABERS Energy rating, and proximity to the newly opened Anzac Train Station, providing outstanding connectivity.
- Restaurant
- Air Conditioning
Property Facts
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553 St Kilda Rd
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