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Main Street Medical Plaza 5858 Main St 3,889 - 8,836 SF of Office/Medical Space Available in Frisco, TX 75033

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HIGHLIGHTS

  • Building signage opportunity on Main Street
  • Superior corner location at Main Street and the Dallas N Tollway

ALL AVAILABLE SPACES(2)

Display Rental Rate as

  • SPACE
  • SIZE
  • TERM
  • RENTAL RATE
  • SPACE USE
  • CONDITION
  • AVAILABLE
  • 2nd Floor, Ste 200
  • 3,889 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • 2026-09-01
  • Lease rate does not include utilities, property expenses or building services
  • Space is in Excellent Condition
  • Fully Built-Out as Standard Medical Space
  • 3rd Floor, Ste 300
  • 4,947 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office/Medical
  • Full Build-Out
  • Now

Customizable suites with generous tenant improvement allowance

  • Lease rate does not include utilities, property expenses or building services
  • Mostly Open Floor Plan Layout
  • Building Signage
  • Fully Built-Out as Standard Medical Space
  • 10 Private Offices
  • Ample Parking
Space Size Term Rental Rate Space Use Condition Available
2nd Floor, Ste 200 3,889 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out 2026-09-01
3rd Floor, Ste 300 4,947 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office/Medical Full Build-Out Now

2nd Floor, Ste 200

Size
3,889 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
2026-09-01

3rd Floor, Ste 300

Size
4,947 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office/Medical
Condition
Full Build-Out
Available
Now

2nd Floor, Ste 200

Size 3,889 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available 2026-09-01

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Space is in Excellent Condition

3rd Floor, Ste 300

Size 4,947 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office/Medical
Condition Full Build-Out
Available Now

Customizable suites with generous tenant improvement allowance

  • Lease rate does not include utilities, property expenses or building services
  • Fully Built-Out as Standard Medical Space
  • Mostly Open Floor Plan Layout
  • 10 Private Offices
  • Building Signage
  • Ample Parking

PROPERTY OVERVIEW

Introducing Main Street Medical Plaza, a versatile property for lease that offers a superior corner location at Main Street and the Dallas North Tollway, providing high visibility and accessibility to prospective tenants. The customizable suites come with a generous tenant improvement allowance, allowing practices to create tailored spaces to suit their needs. Additionally, the property presents a building signage opportunity on Main Street, ensuring prominent visibility. With ample parking and proximity to major health systems, this property offers an exceptional opportunity for Physicians seeking a prime location with unparalleled exposure. Situated in the heart of Frisco, the Main Street Medical Plaza offers an exceptional location for office and medical tenants. The surrounding area is packed with a variety of amenities, including diverse dining options, retail outlets, and recreational facilities, creating a vibrant and convenient environment. Within close proximity to numerous hospitals such as Medical City Frisco and Texas Health Frisco, this location provides ideal accessibility for Physicians and patients. With its prime position in the lively hub of Frisco, the Main Street Medical Plaza provides a unique opportunity for Physicians to grow their practice.

  • Signage
  • Energy Star Labeled
  • Direct Elevator Exposure

PROPERTY FACTS

Building Type
Office
Year Built
2006
Building Height
3 Stories
Building Size
51,280 SF
Building Class
B
Typical Floor Size
17,093 SF
Parking
235 Surface Parking Spaces
Covered Parking
  • Listing ID: 16461812

  • Date on Market: 2025-11-19

  • Last Updated:

  • Address: 5858 Main St, Frisco, TX 75033

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