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Highlights

  • 731 James Street offers move-in-ready suites, highly adaptable layouts, and convenient on-site parking with three lots in Syracuse’s Northside.
  • Attentive on-site local management and security provide businesses with confidence and assurance regarding site operations.
  • Syracuse has strong demographics, with Syracuse University, Upstate Medical University, and Le Moyne College located in the city.
  • Commuting to and from the property is a breeze thanks to quick access to Interstates 81 and 690, Route 11, as well as several bus stops.
  • Northside is a premier destination for businesses less than 1 mile from Downtown Syracuse and beside St. Joseph’s Health Hospital.

All Available Spaces(6)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Build-Out
  • Available
  • 3rd Floor, Ste 310
  • 2,020 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • Now

Spacious third-floor office suite featuring seven (7) private offices, one (1) meeting room that can serve as an additional office, and one (1) breakroom with sink and cabinets. The suite offers generous open space ideal for a reception/waiting area or client-facing workspace. All rooms have windows providing abundant natural sunlight throughout the workday. Ideal for professional services firms, consulting offices, insurance agencies, financial advisors, and similar businesses seeking a well-appointed office with multiple private offices and meeting space.

  • 7 Private Offices
  • 3rd Floor, Ste 315
  • 1,650 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • Now

Well-appointed third-floor office suite featuring five (5) private offices, a pantry with sink, cabinets, and breakroom, and a reception area with a large open seating area. This layout is ideal for businesses that need a professional front-of-house presence combined with private workspace. Windows throughout provide excellent natural sunlight. Well-suited for law offices, medical/therapeutic practices, accounting firms, real estate offices, and service businesses that welcome walk-in or appointment-based clients.

  • 5 Private Offices
  • 3rd Floor, Ste 320
  • 1,112 SF
  • Negotiable
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • Full Build-Out
  • Now

Efficient and well-designed third-floor office suite featuring three (3) private offices, one (1) half-walled office area, a reception/waiting area, closet, and a dedicated storage room. This compact yet functional layout is perfect for small professional teams or satellite offices. Windows provide natural sunlight throughout the suite.

  • Fully Built-Out as Standard Office
  • 3 Private Offices
  • 4th Floor, Ste 410
  • 2,573 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • -
  • Now
  • 4th Floor, Ste 430
  • 1,230 SF
  • 1-10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • -
  • Now
  • 4th Floor, Ste 440
  • 722 SF
  • 10 Years
  • Upon Request Upon Request Upon Request Upon Request
  • Office
  • -
  • Now
Space Size Term Rental Rate Space Use Build-Out Available
3rd Floor, Ste 310 2,020 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out Now
3rd Floor, Ste 315 1,650 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out Now
3rd Floor, Ste 320 1,112 SF Negotiable Upon Request Upon Request Upon Request Upon Request Office Full Build-Out Now
4th Floor, Ste 410 2,573 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office - Now
4th Floor, Ste 430 1,230 SF 1-10 Years Upon Request Upon Request Upon Request Upon Request Office - Now
4th Floor, Ste 440 722 SF 10 Years Upon Request Upon Request Upon Request Upon Request Office - Now

3rd Floor, Ste 310

Size
2,020 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 315

Size
1,650 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
Full Build-Out
Available
Now

3rd Floor, Ste 320

Size
1,112 SF
Term
Negotiable
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
Full Build-Out
Available
Now

4th Floor, Ste 410

Size
2,573 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
-
Available
Now

4th Floor, Ste 430

Size
1,230 SF
Term
1-10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
-
Available
Now

4th Floor, Ste 440

Size
722 SF
Term
10 Years
Rental Rate
Upon Request Upon Request Upon Request Upon Request
Space Use
Office
Build-Out
-
Available
Now

3rd Floor, Ste 310

Size 2,020 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Build-Out Full Build-Out
Available Now

Spacious third-floor office suite featuring seven (7) private offices, one (1) meeting room that can serve as an additional office, and one (1) breakroom with sink and cabinets. The suite offers generous open space ideal for a reception/waiting area or client-facing workspace. All rooms have windows providing abundant natural sunlight throughout the workday. Ideal for professional services firms, consulting offices, insurance agencies, financial advisors, and similar businesses seeking a well-appointed office with multiple private offices and meeting space.

  • 7 Private Offices

3rd Floor, Ste 315

Size 1,650 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Build-Out Full Build-Out
Available Now

Well-appointed third-floor office suite featuring five (5) private offices, a pantry with sink, cabinets, and breakroom, and a reception area with a large open seating area. This layout is ideal for businesses that need a professional front-of-house presence combined with private workspace. Windows throughout provide excellent natural sunlight. Well-suited for law offices, medical/therapeutic practices, accounting firms, real estate offices, and service businesses that welcome walk-in or appointment-based clients.

  • 5 Private Offices

3rd Floor, Ste 320

Size 1,112 SF
Term Negotiable
Rental Rate Upon Request
Space Use Office
Build-Out Full Build-Out
Available Now

Efficient and well-designed third-floor office suite featuring three (3) private offices, one (1) half-walled office area, a reception/waiting area, closet, and a dedicated storage room. This compact yet functional layout is perfect for small professional teams or satellite offices. Windows provide natural sunlight throughout the suite.

  • Fully Built-Out as Standard Office
  • 3 Private Offices

4th Floor, Ste 410

Size 2,573 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office
Build-Out -
Available Now

4th Floor, Ste 430

Size 1,230 SF
Term 1-10 Years
Rental Rate Upon Request
Space Use Office
Build-Out -
Available Now

Matterport 3D Tour

View the Matterport Tour

Property Overview

Work in Syracuse’s Northside neighborhood with 731 James Street, offering convenient access to downtown and all the city has to offer. 731 James Street stands out as a top-tier office destination, providing a peaceful, private atmosphere with seamless access to major roadways. Originally built in 1960, this landmark property has been thoughtfully updated over the years, blending modern touches with classic charm that is sure to impress tenants and visitors alike. Spanning 46,673 square feet across five stories, the building provides flexible floor plans that cater to a wide range of business needs. Situated on 1.35 acres, it boasts abundant surface parking for tenants, their teams, and guests. The expansive lobby welcomes everyone with an impressive volume of natural light from generous windows. With multiple suites available, businesses can easily find and customize spaces to fit their unique requirements. The diverse tenant mix, including professionals, personal service providers, and public administration, creates a dynamic, collaborative environment that encourages growth and synergy. Strategically positioned in Syracuse’s Northside, this property boasts an unrivaled location at the heart of the city’s most dynamic offerings. With direct access to major thoroughfares such as Interstates 81 and 690 and Route 11, employees enjoy exceptionally fast and efficient commutes from every direction. The building’s proximity to Downtown Syracuse and Syracuse University makes it an ideal choice for businesses seeking immediate access to these vibrant hubs. Just steps away from St. Joseph’s Health Hospital, Inspiration Hall, and The Syracuse Orchestra, the property is perfectly placed for those wanting to be close to the city’s cultural and medical landmarks. Additionally, its short distance to Syracuse Hancock International Airport ensures effortless travel and connectivity for tenants and guests alike.

  • Bus Line
  • Property Manager on Site
  • Restaurant
  • Security System
  • Storage Space
  • Basement

Property Facts

Building Type
Office
Year Built
1960
Building Height
5 Stories
Building Size
43,000 SF
Building Class
C
Typical Floor Size
8,600 SF
Unfinished Ceiling Height
10’
Parking
138 Surface Parking Spaces
Covered Parking

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 2nd
  • Cny Fair Housing Inc
  • Services
  • 1st
  • Interreligious Food Consortium
  • Public Administration
  • 4th
  • Peter's Associates,CPAs,P.C
  • Professional, Scientific, and Technical Services

Attachments

View the Floor Brochure
View the Floor Plan
View the Floor Plan
View the Floor Plan
Moderately walkable
70/100
Exceptionally drivable
90/100
Some public transit
50/100
Fairly bikeable
40/100
  • Listing ID: 39833775

  • Date on Market: 2026-04-10

  • Last Updated:

  • Address: 731 James St, Syracuse, NY 13203

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