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Sienna Medical Center 8102 Highway 6 17,827 SF of 4-Star Office/Medical Space Available in Missouri City, TX 77459



Highlights
- 35,654 SF Class A Medical Office Building
- Elevator-Served with Professional Lobby
- Located Within Sienna Master-Planned Community
- First Floor Fully Leased to MD Anderson Cancer Center
- Prominent Highway 6 Visibility - 40k traffic per day
All Available Space(1)
Display Rental Rate as
- Space
- Size
- Term
- Rental Rate
- Space Use
- Condition
- Available
• 17,827 SF Full Second Floor (Contiguous) • Divisible to ±2,500 SF (Subject to Layout) • Delivered in Shell Condition • Elevator-Served Floor with Lobby Access • Located Above MD Anderson Cancer Center • Designed for Medical Office Use • Efficient Rectangular Floor Plate • Strong 4:1,000 Parking Ratio • Natural Light Along Perimeter • Fully Sprinklered (Type II-B Construction) • Built 2025 • Immediate Availability (Confirm Timing)
- Lease rate does not include utilities, property expenses or building services
- Elevator Access
- Natural Light
- DDA Compliant
- Wheelchair Accessible
- Full 17,827 SF Second Floor Opportunity
- Prominent Highway 6 Visibility
- Positioned Within High-Growth Sienna Corridor
- Finished Ceilings: 9’6” - 10’
- High Ceilings
- Emergency Lighting
- Smoke Detector
- Located Directly Above MD Anderson Cancer Center
- 40K cars per day; 1/2 mile from Fort Bend Tollway
- Contiguous Floor Plate – Flexible Demising Options
| Space | Size | Term | Rental Rate | Space Use | Condition | Available |
| 2nd Floor | 17,827 SF | Negotiable | $47.91 CAD/SF/YR $3.99 CAD/SF/MO $854,050 CAD/YR $71,171 CAD/MO | Office/Medical | Shell Space | Now |
2nd Floor
| Size |
| 17,827 SF |
| Term |
| Negotiable |
| Rental Rate |
| $47.91 CAD/SF/YR $3.99 CAD/SF/MO $854,050 CAD/YR $71,171 CAD/MO |
| Space Use |
| Office/Medical |
| Condition |
| Shell Space |
| Available |
| Now |
2nd Floor
| Size | 17,827 SF |
| Term | Negotiable |
| Rental Rate | $47.91 CAD/SF/YR |
| Space Use | Office/Medical |
| Condition | Shell Space |
| Available | Now |
• 17,827 SF Full Second Floor (Contiguous) • Divisible to ±2,500 SF (Subject to Layout) • Delivered in Shell Condition • Elevator-Served Floor with Lobby Access • Located Above MD Anderson Cancer Center • Designed for Medical Office Use • Efficient Rectangular Floor Plate • Strong 4:1,000 Parking Ratio • Natural Light Along Perimeter • Fully Sprinklered (Type II-B Construction) • Built 2025 • Immediate Availability (Confirm Timing)
- Lease rate does not include utilities, property expenses or building services
- Finished Ceilings: 9’6” - 10’
- Elevator Access
- High Ceilings
- Natural Light
- Emergency Lighting
- DDA Compliant
- Smoke Detector
- Wheelchair Accessible
- Located Directly Above MD Anderson Cancer Center
- Full 17,827 SF Second Floor Opportunity
- 40K cars per day; 1/2 mile from Fort Bend Tollway
- Prominent Highway 6 Visibility
- Contiguous Floor Plate – Flexible Demising Options
- Positioned Within High-Growth Sienna Corridor
Property Overview
Sienna Medical Plaza is a newly delivered, two-story, 35,654 SF Class A medical office building strategically positioned along Highway 6 in the heart of the Sienna master-planned community in Missouri City, Texas. The property is purpose-built for healthcare and anchored by MD Anderson Cancer Center, which occupies the entire first floor, immediately establishing the building as a recognized medical destination within Fort Bend County. The available opportunity consists of the full 17,827 SF second floor, offering a contiguous, efficient floor plate designed to accommodate specialty medical, imaging, infusion, oncology support, women’s health, surgical consult, therapy, and other referral-based healthcare providers. Elevator-served and fully sprinklered, the building provides institutional quality construction and professional lobby access, delivering the identity and functionality today’s medical operators require. Sienna is one of the fastest-growing master-planned communities in the Houston MSA, with significant residential density and strong household incomes surrounding the site. The property benefits from direct exposure and access along Highway 6, a primary north-south arterial serving Missouri City and greater Fort Bend County. This corridor continues to experience sustained population growth, creating long-term demand for healthcare services and specialty providers. The presence of MD Anderson on-site creates immediate referral synergy, daily patient traffic, and long-term stability for complementary medical users. Opportunities to lease directly above a nationally recognized healthcare institution within a newly constructed, Class A facility are rare in this submarket
- Signage
- Wheelchair Accessible
- Monument Signage
- Smoke Detector
Property Facts
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- 1st
- MD Anderson Cancer Research Facility
- Health Care and Social Assistance
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Sienna Medical Center | 8102 Highway 6
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