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Sienna Medical Center 8102 Highway 6 17,827 SF of 4-Star Office/Medical Space Available in Missouri City, TX 77459

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Highlights

  • 35,654 SF Class A Medical Office Building
  • Elevator-Served with Professional Lobby
  • Located Within Sienna Master-Planned Community
  • First Floor Fully Leased to MD Anderson Cancer Center
  • Prominent Highway 6 Visibility - 40k traffic per day

All Available Space(1)

Display Rental Rate as

  • Space
  • Size
  • Term
  • Rental Rate
  • Space Use
  • Condition
  • Available
  • 2nd Floor
  • 17,827 SF
  • Negotiable
  • $47.91 CAD/SF/YR $3.99 CAD/SF/MO $854,050 CAD/YR $71,171 CAD/MO
  • Office/Medical
  • Shell Space
  • Now

• 17,827 SF Full Second Floor (Contiguous) • Divisible to ±2,500 SF (Subject to Layout) • Delivered in Shell Condition • Elevator-Served Floor with Lobby Access • Located Above MD Anderson Cancer Center • Designed for Medical Office Use • Efficient Rectangular Floor Plate • Strong 4:1,000 Parking Ratio • Natural Light Along Perimeter • Fully Sprinklered (Type II-B Construction) • Built 2025 • Immediate Availability (Confirm Timing)

  • Lease rate does not include utilities, property expenses or building services
  • Elevator Access
  • Natural Light
  • DDA Compliant
  • Wheelchair Accessible
  • Full 17,827 SF Second Floor Opportunity
  • Prominent Highway 6 Visibility
  • Positioned Within High-Growth Sienna Corridor
  • Finished Ceilings: 9’6” - 10’
  • High Ceilings
  • Emergency Lighting
  • Smoke Detector
  • Located Directly Above MD Anderson Cancer Center
  • 40K cars per day; 1/2 mile from Fort Bend Tollway
  • Contiguous Floor Plate – Flexible Demising Options
Space Size Term Rental Rate Space Use Condition Available
2nd Floor 17,827 SF Negotiable $47.91 CAD/SF/YR $3.99 CAD/SF/MO $854,050 CAD/YR $71,171 CAD/MO Office/Medical Shell Space Now

2nd Floor

Size
17,827 SF
Term
Negotiable
Rental Rate
$47.91 CAD/SF/YR $3.99 CAD/SF/MO $854,050 CAD/YR $71,171 CAD/MO
Space Use
Office/Medical
Condition
Shell Space
Available
Now

2nd Floor

Size 17,827 SF
Term Negotiable
Rental Rate $47.91 CAD/SF/YR
Space Use Office/Medical
Condition Shell Space
Available Now

• 17,827 SF Full Second Floor (Contiguous) • Divisible to ±2,500 SF (Subject to Layout) • Delivered in Shell Condition • Elevator-Served Floor with Lobby Access • Located Above MD Anderson Cancer Center • Designed for Medical Office Use • Efficient Rectangular Floor Plate • Strong 4:1,000 Parking Ratio • Natural Light Along Perimeter • Fully Sprinklered (Type II-B Construction) • Built 2025 • Immediate Availability (Confirm Timing)

  • Lease rate does not include utilities, property expenses or building services
  • Finished Ceilings: 9’6” - 10’
  • Elevator Access
  • High Ceilings
  • Natural Light
  • Emergency Lighting
  • DDA Compliant
  • Smoke Detector
  • Wheelchair Accessible
  • Located Directly Above MD Anderson Cancer Center
  • Full 17,827 SF Second Floor Opportunity
  • 40K cars per day; 1/2 mile from Fort Bend Tollway
  • Prominent Highway 6 Visibility
  • Contiguous Floor Plate – Flexible Demising Options
  • Positioned Within High-Growth Sienna Corridor

Property Overview

Sienna Medical Plaza is a newly delivered, two-story, 35,654 SF Class A medical office building strategically positioned along Highway 6 in the heart of the Sienna master-planned community in Missouri City, Texas. The property is purpose-built for healthcare and anchored by MD Anderson Cancer Center, which occupies the entire first floor, immediately establishing the building as a recognized medical destination within Fort Bend County. The available opportunity consists of the full 17,827 SF second floor, offering a contiguous, efficient floor plate designed to accommodate specialty medical, imaging, infusion, oncology support, women’s health, surgical consult, therapy, and other referral-based healthcare providers. Elevator-served and fully sprinklered, the building provides institutional quality construction and professional lobby access, delivering the identity and functionality today’s medical operators require. Sienna is one of the fastest-growing master-planned communities in the Houston MSA, with significant residential density and strong household incomes surrounding the site. The property benefits from direct exposure and access along Highway 6, a primary north-south arterial serving Missouri City and greater Fort Bend County. This corridor continues to experience sustained population growth, creating long-term demand for healthcare services and specialty providers. The presence of MD Anderson on-site creates immediate referral synergy, daily patient traffic, and long-term stability for complementary medical users. Opportunities to lease directly above a nationally recognized healthcare institution within a newly constructed, Class A facility are rare in this submarket

  • Signage
  • Wheelchair Accessible
  • Monument Signage
  • Smoke Detector

Property Facts

Building Type
Office
Year Built
2025
LoopNet Rating
4 Star
Building Height
2 Stories
Building Size
35,654 SF
Building Class
A
Typical Floor Size
17,827 SF
Unfinished Ceiling Height
14’
Parking
145 Surface Parking Spaces

Select Tenants

  • Floor
  • Tenant Name
  • Industry
  • 1st
  • MD Anderson Cancer Research Facility
  • Health Care and Social Assistance
  • Listing ID: 38477939

  • Date on Market: 2025-05-14

  • Last Updated:

  • Address: 8102 Highway 6, Missouri City, TX 77459

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