Charlotte Regional Business Alliance, founded in 1915, is a nonprofit organization headquartered in Charlotte, North Carolina. The Alliance serves as the voice of business for the 14-county, bi-state Charlotte region, focusing on economic development, public policy advocacy, and workforce initiatives. It was formed through the 2018 merger of the Charlotte Chamber of Commerce and Charlotte Regional Partnership, creating a unified entity to promote regional competitiveness and inclusive prosperity. The organization works with public and private stakeholders to attract investment, support business retention, and foster collaboration across key industries such as financial services, advanced manufacturing, technology, and life sciences. The Alliance also manages programs for leadership development and regional branding, positioning Charlotte as a premier destination for business growth.