4219 S Presa St 4219 S Presa St 1 760 pi² 100% Loué Commerce de détail Immeuble San Antonio, TX 78223 306 253 $ CAD (174,01 $ CAD/pi²)

Position your business or investment in the heart of San Antonio’s growing Southside. Located along the established S Presa corridor, 4219 S Presa St offers a unique combination of location, flexible zoning, and redevelopment potential in an area benefiting from continued public and private investment.
The property features IDZ zoning with C-2 commercial and RM-4 residential uses, creating flexibility for a variety of potential concepts. Whether the vision is an owner-user business, neighborhood commercial operation, residential income property, creative redevelopment, or a combination of uses, the property provides an opportunity to adapt to both current demand and future growth.
LOCATION HIGHLIGHTS
Located along the S Presa corridor
Minutes from Mission San José and the San Antonio Missions
Convenient access to the Mission Reach of the San Antonio River
Near Mission Marquee Plaza / former Mission Drive-In
Close to the historic Hot Wells area
Convenient to the expanding Brooks / City Base employment and commercial district
Easy connectivity to Downtown San Antonio and major thoroughfares
Positioned within the broader Mission and World Heritage corridor
Established neighborhood commercial and entertainment activity along S Presa
The surrounding area continues to benefit from investment in trails, tourism, cultural destinations, infrastructure, residential development, and commercial activity. Its proximity to the San Antonio Missions and Mission Reach provides an additional layer of visibility and long-term appeal for investors and owner-users looking beyond today's use of the property.
THE OPPORTUNITY
4219 S Presa isn't limited to a single vision. Its combination of commercial and residential use potential gives a buyer the ability to evaluate multiple strategies—from operating a business to generating income, repositioning the property, or pursuing a broader redevelopment concept.
For investors, entrepreneurs, developers, and owner-users seeking an opportunity in an established San Antonio corridor with significant history and continued growth around it, 4219 S Presa St deserves a closer look. Zoning info: IDZ AHOD” — Infill Development Zone / Airport Hazard Overlay District — with uses permitted in the C-2 Commercial District and RM-4 Residential Mixed District. I found City records independently repeating that exact formulation for property affected by Ordinance 2011-05-19-0425.
What the zoning actually means
Think of it as three layers:
IDZ = the development framework.
IDZ was created to encourage infill/redevelopment in established urban areas and accommodate more flexible development patterns. Your ordinance then specifically identifies which underlying uses are available.
C-2 = the commercial menu.
This is the big piece from a marketing standpoint. C-2 is San Antonio's standard Commercial District, allowing considerably more business activity than neighborhood/light commercial zoning.
RM-4 = the residential menu.
RM-4 is Residential Mixed, intended for a mixture of residential forms rather than strictly one detached house. The City's purpose statement specifically describes these districts as accommodating mixtures of single-family, two-family and multifamily dwellings.
So, in plain English:
This is essentially an infill property with both a substantial commercial toolbox and residential redevelopment options.
That is stronger and more precise than advertising it generically as "mixed-use zoning."
Commercial possibilities
Based on the C-2 component and the City's use regulations, the practical pool of potential uses is broad. Depending on the exact use classification, permits, Certificate of Occupancy, parking, building code and any overlay restrictions, concepts can include:
Restaurant / café / coffee shop
Retail store / boutique
Professional offices
Attorney, CPA, insurance or real estate office
Medical/dental/clinic uses
Barber shop / beauty salon
Fitness studio / gym
Art gallery / studio
Tattoo/personal-service concepts
Service businesses
Laundry/dry-cleaning uses
Educational/training uses
Restaurant with alcohol
Alcohol-related establishments where the particular use qualifies under C-2 and licensing requirements are satisfied
Neighborhood-oriented retail/service concepts
Live/work or commercial + residential concepts
The current UDC expressly recognizes restaurant/cafeteria, fast-food, commercial gym, professional office, medical/clinic and numerous other commercial/service classifications.
One distinction I'd be careful with in LoopNet marketing is nightclub/bar use. Alcohol sales aren't automatically prohibited in ordinary C-2—the City actually has a separate C-2NA classification when alcohol is prohibited—but that does not mean every alcohol-oriented entertainment use is automatically permitted by right. The exact proposed operation matters.
Residential possibilities
The RM-4 component is where this gets even more useful.
RM-4 is Residential Mixed, not conventional single-family-only zoning. The City's stated purpose specifically contemplates a mixture of residential development and flexible density.
That makes potential residential concepts worth investigating such as:
Single-family residence — keep or renovate the existing house for residential occupancy.
Duplex / two-family concept — potentially convert or redevelop for two dwelling units if all development requirements can be satisfied.
Small multi-unit residential concept — RM-4 is designed to accommodate mixed residential forms, although the number of units actually achievable on this particular parcel will depend heavily on lot area, dimensional requirements, utilities, building/fire code and the controlling IDZ ordinance.
Live/work concept — potentially one of the property's strongest angles: residential occupancy combined with an allowable commercial use.
Residential + commercial redevelopment — potentially commercial use toward S Presa with residential incorporated into the project, subject to site-plan and development requirements.
4219 S Presa St, San Antonio, TX 78223
Buyer to independently verify zoning, permitted uses, development requirements, utilities, and intended use with the City of San Antonio and other applicable authorities.