52 Business Parks for Lease in San Diego, CA, USA

San Diego Office, Office/Medical for Lease - Mission Valley

Mission Grove Office Park at 1545 & 1565 Hotel Circle South comprises two wood-sided office buildings in the highly desirable Mission Valley Submarket of San Diego, California. Mature trees and greenery surround the property, providing the perfect environment for doctors, health practices, therapists, attorneys, and other professionals seeking a tranquil environment. The office park is adjacent to the Hilton Double Tree Hotel, among many other lodging and businesses surrounding Hotel Circle. Numerous retail amenities are close, such as restaurants, retail shopping, banks, fitness facilities, auto dealerships, grocery stores, and the Mission Valley and Fashion Valley Malls. Mission Grove Office Park is less than 2 miles from the historic Old Town San Diego area, Mission Beach is 5 miles west, and Downtown San Diego is 5 miles south. All are easily accessible from the site via the 8 and 163 Freeways. The City of San Diego has significant plans to redevelop the Mission Valley Submarket, including the newly constructed San Diego State University (SDSU) Mission Valley redevelopment of the Qualcomm Stadium site to increase density in the area. At Mission Grove Office Park, businesses will find premier office space in a peaceful west Mission Valley setting.

Date on Market:

2025-07-16

National City Industrial for Lease

Building is part of a well maintained industrial park in a great coastal National City location. Minutes from downtown San Diego with easy access to I-5, I-15, I-805, HWY 54 and 94, and 32nd Street. Close proximity to the Naval Base, and the United Port of San Diego.

Date on Market:

2025-01-15

San Diego Office for Lease - PB/Rose Canyon/Morena

McKee Commercial is pleased to present premier office space for lease within the Jutland Office Park at 4141 Jutland Drive. Suite 300 is on the top floor of the building with a corner location, providing scenic views and bright natural light. There are also skylights for additional natural light. Elevator-served floors have common areas and men's and women's restrooms. Both the first and the second floors have their own lobbies and direct access to parking, so taking an elevator is not required. The two tree-lined parking lots provide ample parking for employees, customers, and guests. Jutland Office Park is a centrally located corporate office building with visibility to the Interstate 5 Freeway. The property is just minutes from the La Jolla, Del Mar, Pacific Beach, and Clairemont neighborhoods. San Diego International Airport is less than 10 miles from the office building, enabling easy business travel. The COASTER commuter rail and multiple MTS transit routes serve the daytime employees of the immediate area. The PB/ Rose Canyon/ Morena office submarket is an affluent realm. Over 60% of the 155,107 population have attained a bachelor's degree or higher level of education, and the average household income surpasses $135,600. Leisure and hospitality, education and health services, and professional and business service sectors are some of the largest employed industries, showcasing the demand and skilled workforce in the immediate area. Inquire today to learn more about leasing the office space on the top floor of the Jutland Office Park, where tenants benefit from stunning views, easy parking, and freeway signage visibility.

Date on Market:

2024-05-24

Santee Industrial for Lease - East County

Date on Market:

2025-12-02

San Diego Office for Lease - Mira Mesa/Miramar

Property Type:

Industrial

Date on Market:

2025-11-21

Poway Industrial for Lease

Positioned in the heart of Pomerado Business Park, this ±28,087 SF industrial sublease opportunity offers a strategic location in Poway, CA, with excellent connectivity to the I-15 corridor. The property features a clear height of ±26 feet, dock and grade loading, and a sprinklered system, making it ideal for a wide range of industrial and distribution uses. The building’s high-visibility corner location enhances brand exposure, while its efficient layout supports operational flexibility. Tenants will benefit from a prime business environment surrounded by leading employers such as General Atomics, GEICO, Sysco, Teledyne, and Honeywell. The property is also within close proximity to major retail and dining options, including In-N-Out Burger, Costco, Home Depot, and Staples, providing convenience for employees and visitors alike. With a parking ratio of ±2.04 per 1,000 SF and easy access to key transportation routes, this location ensures seamless logistics and workforce accessibility. Available February 15, 2026 (or potentially sooner), this sublease runs through August 31, 2028, at a competitive rate of $1.39 PSF Gross. Businesses seeking a well-located, functional industrial space in San Diego County will find this offering an exceptional fit for their operational needs.

Date on Market:

2025-10-30

San Diego Industrial for Lease - Mira Mesa/Miramar

Date on Market:

2025-10-23

Santee Retail for Lease - East County

2,992 SF State of the Art - Fully Equipped Bakery Kitchen Includes Mezzanine Space

Property Type:

Industrial

Date on Market:

2025-10-08

San Diego Industrial for Lease - Kearny Mesa

Industrial space with office space and bathroom (2073SF) total. 8ft Rollup door and 16ft ceiling height in main industrial space. Office portion is around 400-500SF with bathroom. Parking is open parking. Small storage area upstairs above main space.

Date on Market:

2025-09-17

San Diego Industrial for Lease - Mira Mesa/Miramar

Flex Warehouse Building. Large Double-Sided Warehouses w/Bonus Mezzanine Storage. Lobby, 4 Offices, 4 Built-In Workstations. 4 Private Restrooms (Easily Add Shower). 2 Grade Level 12' Roll-Up Doors. Professional Business Park w/ Automatic Gate closed nightly w/ 24 hour access. All New Exterior Paint. Electric Charging Station on-site. Ample Parking. Excellent Central Location, conveniently located between Freeway's I-15 & I-805. Close to Sorrento Valley, UTC, La Jolla, Mira Mesa. Best Location - Best Value. For Private Tour Call/Text Gary Losey 760-331-7057

Date on Market:

2025-08-28

San Diego Industrial for Lease - Kearny Mesa

Date on Market:

2025-08-28

Poway Industrial for Lease

11870 Community Road is a high-image warehouse/distribution building developed by The Techbilt Companies in 2006. Its quality, min 28' clear height, exceptional loading, and convenient Central SD location on the west side of Poway make this an ideal space for a warehouse/distribution business to thrive.

Date on Market:

2025-11-14

El Cajon Office for Lease - East County

Beautiful glass front office, located ideally near Gillespie Field airport.

Date on Market:

2025-12-11

San Diego Industrial for Lease - Mira Mesa/Miramar

Excellent flex space, 758 SF office, 1,860 SF Warehouse with roll-up door. Storefront entrance, great access and parking.

Date on Market:

2025-06-15

San Diego Office for Lease - Kearny Mesa

Date on Market:

2025-06-05

San Diego Flex for Lease - Mira Mesa/Miramar

Date on Market:

2025-12-17

San Diego Flex for Lease - Mira Mesa/Miramar

Date on Market:

2025-04-07

San Diego Industrial for Lease - Kearny Mesa

Property Type:

Flex

Date on Market:

2025-03-21

San Diego Office for Lease - Kearny Mesa

Date on Market:

2025-09-16

San Diego Industrial for Lease - Otay Mesa

Date on Market:

2025-02-18

San Diego Industrial for Lease - Otay Mesa

2655 Melksee Street is a distribution facility in Otay Mesa offering unparalleled access to the US-Mexico border. Located in Otay Mesa’s booming industrial hub, it connects easily to freeways, ports, and rail services for streamlined logistics. Benefit from lower operating costs while capitalizing on the Otay Mesa region’s dynamic growth.

Date on Market:

2025-12-03

San Diego Office for Lease - Sorrento Valley

VENTURE COMMERCE CENTER is located at 11189 and 11199 Sorrento Valley Road on 3.25 acres in a park-like setting. VENTURE COMMERCE CENTER provides business professionals a rare opportunity to own their offices at the heart of San Diego. It is strategically located at the center of UTC, Del Mar, Carmel Valley, Sorrento Mesa and Torrey Pines areas.

Date on Market:

2024-12-03

National City Industrial for Lease

Property Type:

Office

Date on Market:

2024-12-02

Chula Vista Industrial for Lease

This ±14,016 SF industrial space offers a versatile layout with five grade-level loading doors, a fenced yard, and ±1,200 SF of office space. Located in a prime business park, it provides easy access to I-5, public transit, and key retail and amenities throughout San Diego County.

Date on Market:

2024-11-12