52 Business Parks for Lease in San Diego, CA, USA

San Diego Office for Lease - Mission Gorge

Date on Market:

2024-10-14

San Diego Industrial for Lease - Otay Mesa

Class A industrial facility in a corporate image business park.

Date on Market:

2024-10-08

San Diego Office for Lease - Mission Gorge

Date on Market:

2025-07-28

National City Industrial for Lease

Date on Market:

2024-08-28

Poway Office for Lease

±8,000 sf freestanding, two story office building available for sale and for lease

Date on Market:

2024-07-03

San Diego Office for Lease - Kearny Mesa

Collins Business Park is one of the highest quality R&D parks in Central San Diego County. Conveniently located on the I-15 corridor of Kearny Mesa, the project offers unsurpassed freeway access along with a corporate identity

Property Type:

Flex

Date on Market:

2024-05-08

San Diego Office for Lease - Kearny Mesa

Date on Market:

2025-07-11

San Diego Office, Flex for Lease - Scripps Ranch

Date on Market:

2025-05-16

Poway Flex for Lease

Community Business Park is notably one of the most attractive, functional, and well-located properties in the South Poway Business Park. This flex industrial project offers a variety of base sizes including freestanding buildings. It also provides excellent access to scripts Poway Parkway directly to the south and Poway Road to the north.

Date on Market:

2025-07-17

San Diego Office for Lease - Mission Valley

2525 Camino Del Rio South in Mission Valley, San Diego, is a well-located, four-story office building offering 56,847 square feet of multi-tenant space. Recently renovated, the building features updated restrooms and a modernized lobby, providing a professional environment for businesses. The property also includes covered parking, common area conference room, and offers easy access to I-8 and I-15. Its proximity to public transportation, retail, and dining options makes it an ideal choice for businesses seeking a central, convenient location in San Diego.

Date on Market:

2025-07-23

Poway Industrial for Lease

3 building industrial park recently repainted asphalt recently resurfaced, restriped spec suites available

Date on Market:

2025-09-10

San Diego Office for Lease - Mission Valley

7860 Mission Center Court is situated in the Friars Valley Office Park in the Mission Valley submarket of San Diego, California. Sited on 0.76 acres of land, zoned EMX-2, the two-story, 14,260-square-foot office building has attractive amenities featuring ample parking with 36 spaces. In addition, 7860 Mission Center Court boasts large windows that bring in natural light, medical areas, central air and heating, and flexible layouts to fit any tenant's needs. Ideally located in the heart of what is considered one of San Diego's best neighborhoods, Mission Valley is a stunning urban area that is very walkable, offering many outdoor activities and a vibrant art and culture scene. 7860 Mission Center Court is positioned within a six-minute walk from the Friars Mission Center, a strip center anchored by Ralph's supermarket and offering a variety of shops. Mission Valley offers many family-friendly activities, including Snapdragon Stadium, a football venue for San Diego State University currently under renovation. It is set to be complete in September 2022 and is less than three miles from 7860 Mission Center Court. Commuting from 7860 Mission Center Court offers easy connectivity with access to all heavily trafficked highways, Interstate 8, 805, and Esteban Bahena Memorial Highway 163 in a three-minute drive. Easily reach frequently visited hotspots Downtown and Old Town San Diego, and Mission Bay is less than six miles from 7860 Mission Center Court. The train stop at Hazard Center to the Metropolitan Transit System in San Diego is an eight-minute walk for auto-free commuters. When high-end work environments, connectivity, and convenience are critical, 7860 Mission Center Court is the ideal destination.

Date on Market:

2025-11-25

San Diego Office, Flex for Lease - Mira Mesa/Miramar

The Activity Business Center is a five-building, 160,811 square foot, multi-tenant business park located in the eastern portion of Miramar. This centrally located property is minutes from Miramar Road, I-15, and I-805 freeways. Recently renovated enhancing the quality of both the exterior and interior of the property. One of central San Diego’s highest image multi-tenant business parks providing the flexibility to accommodate a variety of users.

Date on Market:

2025-12-03

Poway Office for Lease

13840 Stowe Drive is an approximately 31,295 SF Flex Building located in the Poway submarket. The building is located 3 blocks off Scripps Poway Parkway, offers canyon views and backs up to multiple hiking trail heads that run through the canyon.

Property Type:

Industrial

Date on Market:

2025-08-25

San Diego Industrial for Lease - Sorrento Mesa

Located within the Sorrento Mesa Commerce Center, a 43,842 square foot multi-tenant industrial park, comprised of three buildings along Camino Santa Fe and Flanders Drive. Supported by its central location and bracketed by several arterial freeways, Sorrento Mesa’s profile has taken off in recent years. The neighborhood provides plentiful housing and is within close proximity to high-end shopping, restaurants, and San Diego’s crystalline beaches. Sorrento Mesa’s employers recruit from the pipeline of students graduating from neighboring UC San Diego. High household incomes and advanced education levels are common among residents here. Sorrento Mesa's lineup of industrial tenants has diversified significantly over the past several years. Along with UTC and Torrey Pines, Sorrento Mesa has become one of San Diego’s core innovation hubs and includes notable tenants such as Qualcomm, Thermo Fisher Scientific, Sony, CV Sciences, and Maravai LifeSciences, among others. Green Flash, one of San Diego’s most prominent brewers, also calls Sorrento Mesa home. Demand has remained firmly locked in place for one of San Diego’s most desirable neighborhoods for industrial tenants. It has also become one of the most popular areas for investors. Many are attracted to the full range of industrial assets here that can accommodate a variety of tenants such as traditional industrial users and biotech firms, often at a discount relative to Torrey Pines or UTC.

Date on Market:

2025-12-18

El Cajon Industrial for Lease - East County

Concrete tilt-up construction.

Date on Market:

2025-12-04

Chula Vista Industrial for Lease

The Main Street Business Park is a 63,260 SF multi-tenant industrial park in Chula Vista.

Date on Market:

2025-05-15

San Diego Office for Lease - East County

Reserved parking available. Across the street from Cowells Mountain trailhead and Mission Trails Golf Course. Restaurants nearby.

Date on Market:

2025-10-20

San Diego Flex for Lease - Scripps Ranch

Recent high-end interior improvements and upgraded restrooms enhance the professional ambiance, while exterior façade enhancements and building signage opportunities boost visibility. The property includes a 20’ clear height warehouse with a grade-level roll-up door and heavy power capacity, ideal for light industrial or R&D operations. Fully sprinklered and set within a business park-like environment, the site offers immediate access to I-15, SR-56, and SR-52, ensuring seamless connectivity across the region.

Date on Market:

2025-11-04

Poway Retail for Lease

Existing Chipotle space 2,778 SF Patio space End cap space 2nd generation restaurant improvements

Date on Market:

2025-10-17

San Diego Industrial for Lease - Otay Mesa

Date on Market:

2025-09-02

San Diego Office for Lease - Mission Valley

The property at 5333 Mission Center Road is part of the Mission Center Office Park, a Class B office complex located in the Mission Valley East neighborhood of San Diego, California. Constructed in 1974 and renovated in 2005, the building offers a total of 64,190 square feet of office space across three stories Courtyard atrium, on-site restaurants, proximity to public transportation, and nearby retail and dining options. The property's strategic location provides easy access to Interstates 8, 5, and 15, as well as Highway 163, making it a convenient choice for businesses seeking a central San Diego location .

Date on Market:

2025-05-02

San Diego Land for Lease - Mira Mesa/Miramar

Rare opportunity for vacant, graded land in Miramar. Approximately 2 acres. Perfect for storage yard or a build-to-suit requirement up to 35,000 SF. Directly adjacent to Trepte Industrial Park. Close proximity to I-15 and I-805 freeways. Vacant land for lease in this area is extremely rare. Grading is currently in progress, exact size of the pad to be determined at a later date.

Property Subtype:

Industrial

Date on Market:

2025-05-21

San Diego Industrial for Lease - Otay Mesa

Date on Market:

2024-09-03