48 Lofts for Lease in Saint Louis, MO, USA

Webster Groves Office for Lease - Brentwood/Maplewood

This 3,600± SF available two-story office property (1,800± SF per level) offers flexible use with dual private entrances, allowing each floor to operate independently. Large storefront windows provide abundant natural light, complemented by a side garden and outdoor seating area. Situated at the high-traffic intersection of Gore and Lockwood Avenue, the property includes five on-site parking spaces plus ample street and structured parking. Recent upgrades feature new energy-efficient HVAC systems. Located within a strong business corridor and walkable to Old Webster’s dining and retail district, this is an ideal opportunity for office or boutique users.

Date on Market:

2026-03-18

Saint Louis Office/Medical for Lease

Prime Olive St Storefront at Paul Brown Loft Apartments Showcase your business in a high-visibility storefront located in the heart of downtown St. Louis. The street-level commercial space at Paul Brown Loft Apartments places your business in one of downtown St. Louis’ most recognizable historic buildings and in the heart of the entertainment corridor. The location sits steps from the convention center and surrounded by established restaurants including Mizu Sushi, Sen Thai Asian Bistro, Rooster, and Sugarfire Smokehouse, creating steady foot traffic from residents, office workers, and visitors. This property is a recent addition to the Olive Holding portfolio. The company has renovated nearly 1,000 loft apartments throughout downtown and is actively repositioning street-level storefronts like this one into vibrant neighborhood amenities for residents, condo owners, hotel guests, and convention-center visitors. The area is evolving quickly—this is an opportunity to join a growing, energized downtown community. Key Features • Listed lease rate plus proportional share of utilities • Fully built-out retail space—move-in ready • Located in-line with other active storefronts • Space is in excellent condition • Central air and heating • Private restrooms • High ceilings with exposed elements • Plug-and-play layout • After-hours HVAC available • Finished ceiling height: 17 ft • Tall ceilings and a high-visibility storefront ideal for branding This prominent commercial building at 817 Olive Street offers excellent exposure, modern upgrades, and unbeatable walkability to the city’s top amenities. - Street-level storefront ideal for retail, service businesses, or client-facing operations - Variety of suites available to fit different business sizes and layouts - Walking distance to restaurants, retail, transit, and all downtown conveniences - Modern, renovated main lobby that creates a strong professional impression - High-speed fiber internet for fast, reliable connectivity - Perfect for businesses seeking both visibility and a central downtown presence A standout opportunity for any business looking to establish itself in a thriving, walkable urban location. We have a 3,540 sq ft commercial space now available for lease. This versatile unit is ideal for a variety of business types and offers excellent visibility and foot traffic. We’re seeking a 1-5-year lease term.

Property Type:

Retail

Date on Market:

2026-03-06

Saint Louis Flex for Lease

Prime Olive St Storefront at Paul Brown Loft Apartments Showcase your business in a high-visibility storefront located in the heart of downtown St. Louis. The street-level commercial space at Paul Brown Loft Apartments places your business in one of downtown St. Louis’ most recognizable historic buildings and in the heart of the entertainment corridor. The location sits steps from the convention center and surrounded by established restaurants including Mizu Sushi, Sen Thai Asian Bistro, Rooster, and Sugarfire Smokehouse, creating steady foot traffic from residents, office workers, and visitors. This property is a recent addition to the Olive Holding portfolio. The company has renovated nearly 1,000 loft apartments throughout downtown and is actively repositioning street-level storefronts like this one into vibrant neighborhood amenities for residents, condo owners, hotel guests, and convention-center visitors. The area is evolving quickly—this is an opportunity to join a growing, energized downtown community. Key Features • Listed lease rate plus proportional share of utilities • Fully built-out retail space—move-in ready • Located in-line with other active storefronts • Space is in excellent condition • Central air and heating • Private restrooms • High ceilings with exposed elements • Plug-and-play layout • After-hours HVAC available • Finished ceiling height: 17 ft • Tall ceilings and a high-visibility storefront ideal for branding This prominent commercial building at 210 North 9th Street offers excellent exposure, modern upgrades, and unbeatable walkability to the city’s top amenities. - Street-level storefront ideal for retail, service businesses, or client-facing operations - Variety of suites available to fit different business sizes and layouts - Walking distance to restaurants, retail, transit, and all downtown conveniences - Modern, renovated main lobby that creates a strong professional impression - High-speed fiber internet for fast, reliable connectivity - Perfect for businesses seeking both visibility and a central downtown presence A standout opportunity for any business looking to establish itself in a thriving, walkable urban location. We have a 1,079 sq ft commercial space now available for lease. This versatile unit is ideal for a variety of business types and offers excellent visibility and foot traffic. We’re seeking a 5-year lease term.

Date on Market:

2026-03-06

Saint Louis Office for Lease - St Louis City

Date on Market:

2026-02-23

Saint Louis Retail for Lease - CBD

Prime Washington Avenue location in downtown St. Louis -- steps from the convention center, near established restaurants such as Mizu Sushi, Sen Thai Asian Bistro, Rooster & Sugar Fire Smokehouse. This property is a new acquisition within the Oliver Properties portfolio. Oliver Properties has purchase and renovated ~1,000 loft apartments in the neighborhood and is repositioning street-level storefronts like this one as new neighborhood amenities for apartment dwellers, condo owners, convention center/hotel visitors, office users, ... come be a part of this fast-changing downtown neighborhood.

Date on Market:

2026-02-20

Saint Louis Office for Lease - CBD

First floor loft style commercial space at the corner of 10th and Locust featuring high ceilings, polished concrete floors, original columns, and expansive storefront glass that brings in exceptional natural light. The building is currently being redeveloped with 60 new apartments above, creating an immediate built in customer base, and is supported by two parking garages in the immediate vicinity. The open flexible layout is well suited for creative office, boutique fitness, wellness, gallery, showroom, and other destination driven users that benefit from character, visibility, and surrounding residential density. Two suites totaling over 8,000 square feet can be leased individually or together.

Date on Market:

2026-02-12

Saint Louis Retail for Lease - CBD

Salient Realty Group is pleased to present this turn-key restaurant opportunity located on Washington Ave in the heart of Downtown St. Louis. Next door to the City Museum and situated right next to multiple highly acclaimed restaurants, this space is a gorgeously finished with exposed brick and columns along with floor to ceiling windows that enjoys beautiful views of one of St. Louis's most iconic streets. Positioned within a short 5 minute drive of Energizer Park and Enterprise Center as well, this property have an average 3,500 people commuting past daily. The property is +/- 8,422 square feet of built-out restaurant space, the first floor is 5,324 square feet with a large "horseshoe" bar, dining room, entertainment stage, and commercial kitchen. The second floor consists of 3,098 square feet with its own bar and large dining room with large wall to wall windows for an unmatched natural ambience. Don't miss this fantastic opportunity to get this beautifully finished, 2nd Gen restaurant space with all FF&E included!

Property Type:

Multifamily

Date on Market:

2026-02-11

Saint Louis Flex for Lease - CBD

Property Type:

Specialty

Date on Market:

2026-02-09

Saint Louis Retail for Lease - CBD

Shopfront on Wash Ave just west of Tucker BLVD -- very close to Insomnia Cookies. This property is new to market and priced right. Landlord is looking to make deals for the right user. Close to downtown St. Louis' visitors & convention center (America's Center & the Dome); close to St. Louis University Law School; close to civil & federal courthouses; centered in the walkable Wash Ave neighborhood with thousands of loft apartments and condos above.

Property Type:

Multifamily

Date on Market:

2026-02-09

Saint Louis Office/Retail for Lease - St Louis City

1935 Sidney St., St. Louis, MO 63104 BUILDING FOR LEASE 6,000+/- Sf. Multi-Use / Church Building. Welcome to 1935 Sidney Street in the Benton Park neighborhood, the former Saint Agnes Roman Catholic Church, originally built in 1891. This stunning and historic building features copper-topped bell towers, a choir loft, soaring 40-foot ceilings, and beautiful architectural columns that create a truly inspiring interior. The property has undergone extensive renovations, including a new roof, new HVAC system, a full interior repaint, and beautifully refinished hardwood floors throughout. Improvements also include two new three-stall restrooms and a kitchenette. Potential uses include a place of worship, dance or yoga studio, fitness center, art exhibition or performance space, meeting hall, wedding venue, and more. This is a highly unique property, ready for a creative tenant. Lease price $4,500 per month plus NNN.

Property Type:

Specialty

Date on Market:

2026-01-27

Saint Louis Retail for Lease - South County

Family owned strip center at the corner of Tesson Ferry and Baptist Church Road.

Date on Market:

2026-01-15

Saint Louis Office/Retail for Lease - CBD

Bring your concept to the heart of St. Louis’ fastest-growing entertainment district. The first floor of 2007 Locust St sits in Downtown West with direct views toward the new St. Louis CITY SC stadium (Energizer Park/CityPark) and the Union Station Ferris wheel, and is just a short walk from the Schlafly Tap Room at 2100 Locust. RealtyMastersSTL.com +2 Wikipedia +2 This mixed-use brick building totals roughly 4500 sq ft on a 7,750 sq ft lot, with the first floor ideal for a restaurant, taproom, bar, coffee shop, or destination retail concept. Crexi From Locust you get strong street presence and visibility on a quieter stretch of the corridor, while the rear of the building offers a drive-in door, dock access, and 4–6 off-street parking spaces for staff, deliveries, or VIP customers. RealtyMastersSTL.com Surrounded by residential lofts, creative offices, and walkable destinations, the space lets you capture pre- and post-game traffic from CITY SC matches, visitors to Union Station, and daily neighborhood foot traffic. Whether you’re building out a full kitchen, brewery concept, or modern retail/experience space, 2007 Locust gives you the bones, the location, and the story to anchor a flagship location.

Property Type:

Retail

Date on Market:

2025-11-29

Saint Louis Office, Retail for Lease - I-270/Maryland Heights

Date on Market:

2026-03-16

Saint Louis Office, Retail for Lease - St Louis City

Immerse your business in the vibrant energy of Saint Louis! The area surrounding 904 S 4th Street offers a thriving mix of business, culture, and leisure. Take advantage of proximity to the iconic Gateway Arch, with its inspiring architecture and scenic views, perfect for lunchtime strolls or client outings. Nearby, Kiener Plaza Park provides a green oasis for relaxation and outdoor events. Explore the rich cultural offerings at Citygarden, an urban sculpture park, or enjoy world-class dining and entertainment in the nearby entertainment districts. With prime access to public transportation and major highways, this location seamlessly combines business with pleasure.

Date on Market:

2026-02-26

Saint Louis Office/Retail for Lease - CBD

Property Type:

Multifamily

Date on Market:

2025-02-27

Saint Louis Retail for Lease - CBD

Corner storefronts at Washington AVE and Tucker BLVD in downtown St. Louis' Central Business District. Next to Insomnia Cookies.

Date on Market:

2025-02-27

Saint Louis Office for Lease - St Louis City

Multiple Office Suites now available within the Hampton Manor Office Complex. Available suites range from 2,130 S.F. to 4,260 S.F. which are ideally configured for small business use. Building and pole signage is available for Tenants and there are 45 parking spaces (2.77/1,000 SF) available. The office complex is professionally managed and maintained. Located in the North Hampton neighborhood of South St. Louis on Hampton Avenue between Arsenal and Chippewa Street with convenient access to I-64 and I-44.

Date on Market:

2025-01-21

Saint Louis Office for Lease - St Louis City

The former, historical, American Furnace Building is located in the heart of Saint Louis, MO. This prime location offers easy access to shopping, dining, city parks, Washington University, St Louis University, and major metro routes. With close proximity to the BJC Complex and major interstates 64 and 44, this location is perfect for those seeking convenience and accessibility. Enjoy high visibility in this bustling area, making it a great choice for a business to be in the center of it all. Don't miss out on this fantastic opportunity to work in a vibrant and dynamic neighborhood. Contact us today to schedule a tour of this office space!

Date on Market:

2025-03-05

Saint Louis Retail for Lease - St Louis City

Redeveloped in 2016, the Lofts at Euclid at 625 N Euclid Avenue is a prime mixed-use property in St. Louis' sought-after Central West End. This amenity-rich brick building features 87 upscale residential units and well-appointed ground-level retail spaces, ideal for diverse businesses seeking high visibility at a prominent corner location. The former Fields Foods space, approximately 7,893 square feet, includes a large refrigerator and offers versatile potential for uses such as a butcher shop, restaurant, deli, convenience store, or grocer. For added flexibility, the space can be subdivided into smaller units starting at 2000 square feet, tailored to tenants' needs. Tenant improvements (TI) are negotiable based on approved credit and terms. Strategically positioned between Washington University and St. Louis University, 625 N Euclid Avenue benefits from its proximity to the Metrolink Station, Barnes Jewish Hospital, and major employers like Cortex, located just 1.5 miles away. The location attracts steady visibility and drive-by traffic, with easy access to Interstate 64 via S Kingshighway Boulevard and ample surface street parking for customers. Additionally, the property is near Forest Park, a 1,300-acre public destination home to the renowned St. Louis Zoo, ensuring exposure to residents and visitors. With total consumer spending of $3.9 billion within a 5-mile radius, this property offers an unparalleled opportunity to establish or expand business in a thriving community.

Property Type:

Multifamily

Date on Market:

2024-11-27

Webster Groves Office for Lease - Brentwood/Maplewood

Rare opportunity to lease high-end creative office space in the Old Webster business district.

Date on Market:

2024-10-24

Saint Louis Office for Lease - St Louis City

12-14 Maryland has a long history in St. Louis first as a department store and for the last few decades as a home to restaurants and offices.

Date on Market:

2022-12-08

Saint Louis Office for Lease - CBD

Largest Ameren UE Substation in the city. Circa 1930's industrial building that has been converted into a telecommunications switch site. Contains 70,000-90,000 sf floorplates. Floor load up to 250 lbs/sf. Roof load up to 150 lbs/sf enable right condition for transmission and reception facilities. Also includes 7 large freight elevators that can hold 15,000 lbs and 6 additional elevators that can hold 7,000 lbs. Building has 2 floors of covered parking. Unlimited power available includes an additional building vault for increased power needs in the future. Updated electrical power with an on-site Ameren UE substation, 13,800 volts with grounding at substation site. Multiple locations available for placement of tenant generator - 50 covered loading docks make excellent generator pads. Space for tenant fuel tank is also available. Roof space is available for wireless transmission equipment and dry coolers. On-site providers include AT&T, NextLink, Level 3, SWB, AXXON Telecom and Quest Data Center and AI space readily available Located near Washington Ave restaurants and adjacent loft renovations. Property has four points of entry for redundant fiber optic service providers. Seven riser locations run the height of the building. Extended D-Mark from the Main Point of Entry (MPOE) to accommodate cross connections; if tenant chooses to distribute outside of leased premises. New ADA restrooms throughout building. On-site security. Wet pipe sprinkler system, tenant may install individual dry fire suppression system. · 7 Story 626,760 SF Office Building in Downtown St. Louis Business District · Newly Renovated Lobby · Planned Renovations in the Upcoming Year Include: * Rehabilitated Windows * Rebuilt Passenger Elevators * New Restrooms on Office Floors * Upgraded Elevator Lobbies & Corridors · On-Site, Secured Underground Parking for 450 Cars · 14’ Ceiling Height · 7th Floor/Larger Users Have the Ability for Several Private Courtyards · Half-Lite, Louvered & Skylight Windows · Exceptional Fiber Access to Building, Entry at Four Corners of Building · 24-Hour Key-Fob Access & Lobby Attendant During Day Hours · 2 Full Height Passenger Elevators & 4 Freight Elevators with Capacity to 5,000 lbs. · Concrete Floors, Fluted Columns & Coffered Ceilings

Date on Market:

2022-11-16

Saint Louis Retail for Lease - South County

Heavy traffic area, major street. Newly refurbished after fire. All new HVAC systems, new roof with up to date thicker insulation. Open slate to prepare for your business. Far right end of plaza. Right now we are offering the first two months rent free.

Date on Market:

2024-09-30

Saint Louis Retail for Lease - St Louis City

Date on Market:

2020-06-19