48 Lofts for Lease in Saint Louis, MO, USA

Saint Louis Office for Lease - I-270/Maryland Heights

On site property management, AT&T fiber, building signage available, storage available, break room/vending, card key access, covered executive parking. Located in the West Port submarket.

Date on Market:

2023-07-05

Clayton Office for Lease

Date on Market:

2022-09-19

Clayton Retail for Lease

THIS SPACE IS AVAILABLE. Property is now vacant. Space was a retail seller of gooey butter cakes. Property will rent for $1,250 per month. Please call 314-707-8444 to tour the space.

Date on Market:

2026-03-04

Saint Louis Flex for Lease - CBD

Exciting retail opportunity available in the heart of Downtown St. Louis! This 1,800 SF suite, located next to U-Haul Moving & Storage at 418 S Tucker Blvd, offers excellent visibility and consistent foot traffic. Ideal for a quick-service restaurant, coffee shop, or retail concept, the space features prominent street frontage, convenient on-site parking, and easy access to major highways and public transit. Surrounded by government offices, businesses, and residential developments, this high-traffic location is perfect for operators looking to establish a strong presence in a growing urban corridor.

Property Type:

Specialty

Date on Market:

2022-08-26

Saint Louis Office, Office/Retail for Lease - St Louis City

The Weisert Building consists of two attached adjacent buildings - North Building is heavy timber (1903); South Building (1924) is concrete two way slab with mushroom capital columns. Renovated 2023. Classis loft construction with exposed structure, HVAC, electrical. Rooftop Penthouse conference room.

Date on Market:

2026-02-15

Saint Louis Retail for Lease - South County

Commercial retail property for rent about 6000 sqft ,new heating and cooling system, everything is electric new gutters new roof, updated electric 3 face and 200 Amp. For more info please call 314-393-2911 AT Real Estate LLC.

Date on Market:

2025-05-04

Saint Louis Retail for Lease - CBD

Originally built in 1896 by architect Albert Groves, this building underwent a full rehab in 2017. Each floor was modernized with high ceilings, exposed brick, and new elevator access. Located in the heart of the Washington Avenue Garment District, you can step out front onto the cobblestone zipper that runs along the heavily foot-trafficked street. This mixed-use retail and office building is an ideal location, nestled among the downtown residents, businesses, and bustling tourists in St. Louis. Recently updated with new LED lighting throughout, keyless access system, and security cameras throughout.

Property Type:

Office

Date on Market:

2026-03-10

Saint Louis Office, Office/Medical for Lease - South County

A well-maintained 2 story professional building. Located just South of Mercy Hospital South & Medical Center Campus in South County. This building has excellent visibility due to its location on Tesson Ferry Rd. Has a nice tenant mix and plenty of parking.

Date on Market:

2021-10-08

Saint Louis Office for Lease - CBD

• Directly Across Olive from the Proposed New MLS Stadium • Potential for Retail/Restaurant on the 1st floor • Beautiful Historic Class A Office Building • Great Central Location in Booming Downtown West • Exposed Beams and Architectural Features • Secured Access • Secure Parking Adjacent to Building • Multiple Spaces and Floors Available

Date on Market:

2023-06-10

Granite City Office for Lease - Illinois

Located 10 minutes from Downtown St. Louis and renovated in 2010, this one floor 10,250 SF office building has multiple private offices, large open rooms, and an abundance of natural light. The space sits within America's Central Port secure and 24/7 monitored facility, and is zoned in a HubZone qualified district. The building is served by AT&T Fiber, has access to America's Central Port administrative conference rooms, as well a 50-75 person conferencing area with AV equipment for presentations, a YMCA child care directly across the street, and green space, walking paths and pick-nick tables for outdoor enjoyment. Please reference building floor plan and interior photos for an overview of this building.

Date on Market:

2025-05-14

Saint Louis Multiple Space Uses for Lease - CBD

Up to 9,015 SQ FT per floor - divisible. 1430 Washington Avenue has multiple professional and/or creative office suites for lease. Four blocks west of T-Rex. One block East of St. Louis Fashion Fund's Fashion Incubator on Washington Avenue. This property is near the St. Louis City Civil Court house, the Thomas F. Eagleton Federal Court building, the St. Louis City Central Library, City Museum and all nearby Washington Avenue lofts and restaurants/retail. The property is fourteen short blocks from the Gateway Arch and walking distance to Peabody Opera House, as well as the St. Louis Blues & St. Louis Cardinals sports venues. Just 1.5 miles from the new $1.7B National Geospatial-Intelligence Agency West facility, or Next NGA West. Call 314-280-6646 for more information.

Date on Market:

2025-12-21

Saint Louis Flex for Lease - St Louis City

The Flex use building currently houses the roaster for COMA coffee with plans to renovate the building for a retail & office or residential use.

Property Type:

Industrial

Date on Market:

2025-05-13

Saint Louis Office, Retail for Lease - CBD

Originally constructed in 1896, the Cast Iron Building has been beautifully renovated to accommodate the needs of modern-age businesses. The building is 3-stories and is elevator served. The spaces have modern loft design with visible brick walls, wooden floor joists, exposed duct work, and contemporary light fixtures. Multiple floor plans and layouts are available for both retail and office tenants. Location Overview: 2nd Street on Laclede's Landing was recently re-constructed with new sidewalks, lighting, landscaping and all of the cobblestones were removed and re-laid for an even driving surface.

Date on Market:

2022-07-08

Saint Louis Office for Lease - South County

Leasing Opportunity – 4167 & 4171 Crescent Drive. Now available for immediate occupancy, 1,500 to 2,500 square feet of versatile office space ideally suited for creative, professional, or small business use. Located just off Lindbergh at the I-55 and I-270 corridor, this prime location offers excellent accessibility and visibility. Both buildings are fully ADA accessible and provide ample on-site parking, making them convenient and accommodating for clients and staff alike.

Date on Market:

2025-07-22

Saint Louis Office for Lease - CBD

Date on Market:

2025-06-23

Saint Louis Coworking for Lease - CBD

Property Type:

Office

Date on Market:

2025-06-04

Saint Louis Retail for Lease - St Louis City

Exceptional Leasing Opportunity: Historic Moolah Temple - Theatre & Lounge on Lindell Blvd 3821 Lindell Blvd - Turnkey Theatre & Lounge, an iconic venue rich in history and architectural splendor. Originally constructed in 1912 as the Moolah Temple, this property underwent a meticulous restoration in 2002, marrying its historic essence with modern functionality. The space features a large single-screen theatre with balcony seating. Complementing the theatre is an 8-lane bowling alley, complete with bar and game area. Positioned adjacent to SLU's Campus the venue benefits from high foot traffic and visibility on Lindell Blvd, a prime location enhanced by ample off-street parking in the adjacent Moolah parking garage.

Property Type:

Multifamily

Date on Market:

2024-03-28

Saint Louis Office for Lease - St Louis City

CIC St. Louis offers a dynamic and collaborative environment for entrepreneurs, startups, and enterprises in Saint Louis, Missouri. Across three vibrant locations in the heart of Cortex, experience 160,000 square feet of modern office solutions. Members can access beautifully designed office and coworking spaces, wet lab facilities, event spaces, shared amenities such as meeting rooms, phone booths, and fully stocked kitchens. Whether needing a shared space, a remote plan, or a private office for a growing company, CIC St. Louis provides access to workspaces and amenities tailored to fit all business needs. Flexible workspaces can accommodate teams of 50+ people. Private labs range from 500 to 1,100 square feet with ample room for four to 10-person teams. All labs have sinks, benches, stools, and storage space. Members have access to a shared equipment room, including an autoclave, sterilizer, Milli-Q water purification system, and an industrial ice machine. Most labs have chemical fume hoods and eyewash stations. (All labs with chemical fume hoods include eyewash stations.) The client is responsible for special and/or mandatory certifications, and CIC provides complimentary biowaste pickup twice a year. Over the past 20 years, Cambridge Innovation Center (CIC) has become one of the largest startup ecosystems in the United States and worldwide, with locations in North America, Asia, and Europe. CIC specializes in creating communities and accelerating the growth of innovation-based companies by promoting collaboration. CIC members can easily adapt their workspace solutions to meet their real-time needs through month-to-month terms and flexible office plans.

Date on Market:

2023-04-21

Saint Louis Office for Lease - South County

A well maintained 2 story multi-tenant office building. Located in South St. Louis County in the City of Green Park. Has lots of amenities nearby like Lion's Choice, Tucker's Place, Starbucks, lots of hotels, just to name a few. This building overlooks I-55 and is just minutes to I-55 and I-270. Building signage possibilities for a larger tenant.

Date on Market:

2021-09-29

Saint Louis Retail for Lease - St Louis City

The Metropolitan Flats building is located at the heavily-trafficked, highly visible intersection of Forest Park Avenue (17,471 vpd) & Euclid Avenue (4,454 vpd) which is near Forest Park, one of the nation’s largest urban parks, with 13 million visitors per year. The building also underwent a $11 million building renovation, which was completed in 2020.

Property Type:

Multifamily

Date on Market:

2025-01-28

Cahokia Office for Lease - Illinois

2,000 SF Medical/Office Suite. This 2,000 SF suite is well-suited for a medical, clinical, or professional office user. The space was previously occupied by a medical tenant and retains a functional layout reflective of that use. The suite features: Reception Area — A dedicated reception station positioned at the entrance, Waiting Area — A generously sized waiting room adjacent to reception, Five Treatment/Exam Rooms — A row of five private treatment rooms along the rear of the suite, ideal for clinical, therapy, or private consultation use, Two Private Offices — Two enclosed office spaces offering flexibility for administrative or executive use, Kitchen/Break Area — A full kitchen with cabinetry and sink, suitable for staff use, Utility Room — A dedicated utility/mechanical space, Storage — A separate storage area, & Two Restrooms — Conveniently located within the suite. The layout is well-configured for a medical, behavioral health, physical therapy, or similar healthcare provider, though it could also be adapted for general professional office use. Current neighboring tenant is Kevin Schmidt, State Representative District 114. High traffic location with 14,300 ADT.

Date on Market:

2026-03-24

Saint Louis Office for Lease - Bridgeton/I-70

Date on Market:

2025-02-25

Saint Louis Retail for Lease - St Louis City

1700 S. Jefferson is a first floor 5,170 S.F. retail location for lease. This space offers floor to ceiling windows that provide great natural light as well as high ceilings. This building is located at the intersection of S. Jefferson and Hwy 44 in the Lafayette Square neighborhood.

Property Type:

Multifamily

Date on Market:

2020-01-21

University City Retail for Lease - Creve Coeur/Hwy-67

To be delivered in a vanilla box space condition, LED interior lights. End cap. Triple net charges estimated to be $6.25/SF for 2026

Date on Market:

2024-06-11