117 Lofts for Lease in San Diego, CA, USA

National City Multiple Space Uses for Lease

Southport Industrial Park is a 297,533 SF multi-tenant industrial park with suites ranging from 829 RSF to 24,400 RSF. Numerous on-site retail amenities featuring In-N-Out Burger & Denny’s. Walking distance to 24th Street Trolley Station. Located within HubZone & Enterprise Zone. Ten minutes to the Mexico Border crossing, San Diego International Airport and Downtown San Diego.

Date on Market:

2026-02-17

Solana Beach Office for Lease - North Beach Cities

Garden Office building with lots of glass, close to many restaurants with fast access to I - 5.

Date on Market:

2025-07-23

San Diego Multiple Space Uses for Lease - College Area

Spaces Available for Lease: Suite 202 - 1,175 SF, contains five small private offices, check in area. Leased 8.10.2025 Suite 206 - 1,450 SF, contains four private offices, large meeting room, leased 9-1-2024 ! Suite 209 - 2,045 SF, contains six private offices, private restroom, employee lounge, Suite 210 - 3,115 SF, secured check in area, open central space, and private offices. Suite 210A - 2,100 SF, private offices, private bathroom, and meeting room Suite 212A - 200 SF, private office leased 8/1/2025 Suite 218 - 120 SF, private office leased 7/1/2025

Date on Market:

2026-03-19

San Diego Multiple Space Uses for Lease - Downtown

Date on Market:

2024-07-19

San Diego Office for Lease - Mission Valley

3636 CAMINO DEL RIO NORTH IS A 28,551 SF, TWO STORY PROFESSIONAL OFFICE BUILDING LOCATED IN CENTRAL MISSION VALLEY. THE PROPERTY FEATURES TWO ENTRANCES FOR EASY ACCESS THROUGHOUT. SUITES INCLUDE UNRESERVED ONSITE PARKING AT A RATIO OF 2.9 PER 1,000 SF LEASED. ALSO INCLUDED IS VISITOR PARKING AND AN ELEVATOR ONSITE. CLIENTS AND EMPLOYEES WILL ENJOY BEING ONLY MINUTES FROM THE RESTAURANT AND RETAIL AMENITIES OF MISSION VALLEY. DON’T MISS OUT ON THE PROFESSIONAL OFFICE SPACES AVAILABLE AT 3636 CAMINO DEL RIO NORTH.

Date on Market:

2025-10-09

San Diego Office for Lease - Kearny Mesa

Date on Market:

2025-01-31

San Diego Retail for Lease - PB/Rose Canyon/Morena

Retail, Medical, and Office Suites AVAILABLE Across from Home Depot, Sprouts, and Target DO NOT CALL! - INQUIRE VIA EMAIL OR THROUGH THE WEBSITE ONLY Due to the amount of spam calls, direct inquiries via the website are preferred Current Opportunities: **** Turn Key Medical Suite up to 4,356sf **** **** High Visibility Office/Retail Suites Available **** Ample Parking, Signalized Intersections, Excellent Tenant Mix Tesla Superchargers onsite High Visibility Retail & Office Center at signalized intersection on Genesee Competitive Lease Rates! Flexible Space Options! National Co-Tenants +/-400 Parking Spaces Situated in Major Retail Area 70,781sf of Total Retail/Office Well situated storefronts/suites Strong Area Demographics BUSY SHOPPING AREA with National Retailers Just off of Balboa & Genesee Excellent tenant mix in the area: Target Marshalls Walgreens, Rite Aid, & CVS Home Depot Pep Boys, O' Reilly, & Auto Zone Sprouts, Vons, & Albertsons Kohl's Bank of America & Wells Fargo The Habit Burger Grill and Much More! Traffic & Demographic Information: Exclusive Listing - Contact Brokers for Details and Showings DO NOT CALL! - INQUIRE VIA EMAIL OR THROUGH THE WEBSITE ONLY Due to the amount of spam calls, direct inquiries via the website are preferred

Date on Market:

2026-02-06

San Diego Office for Lease - Mission Valley

Two story office building with prime street frontage and central mission valley location. Ample parking, close proximity to public transit and highway 8 and highway 15, Kaiser Hospital, Home Depot, SDSU, Qualcomm Stadium, etc. Available now visit www.eldpinc.com for more information.

Date on Market:

2026-01-15

San Diego Office for Lease - Old Twn/S Arena/Pt Loma

Date on Market:

2026-03-25

San Diego Coworking for Lease - Downtown

Featuring a prominent location in the Downtown Financial District and adjacent to the historic Gaslamp Quarter, this 1913 building has been renovated to offer the latest amenities, including a rooftop deck and direct fiber internet. Here you will find six floors of state-of-the-art private offices and office suites that can accommodate teams of one to 50 people, bike storage, and the best coworking space in San Diego. Located at the heart of San Diego’s bustling Financial District, Expansive ’s Sixth Ave. building offers outstanding accessibility to the restaurants, hotels, and nightlife of the popular Gaslamp and Little Italy neighborhoods. Easy access to I-5 and State Route 163, while the 5th Ave. light rail station less than a block away connects clients with greater San Diego.

Property Type:

Office

Date on Market:

2026-03-09

San Diego Office/Retail, Retail for Lease - Downtown

This is a beautiful 1910 era historic specialty building. For many years this building has served as home for many of San Diego's finest jewelry manufacturers, wholesalers, retailers and repair shops. This building is perfect for those in the jewelry trade, having an average 90% occupancy rate, ample parking and a great location on the edge of the Gaslamp District. This space could also be a great location for antique dealers. Plenty of paid parking on-site and in area. At the corner of 6th and E, conveniently located two blocks from Horton Plaza and near the new downtown ballpark. Easy access to freeways. Within short walking distance to the Trolley, Courthouse, Main Library and the Post Office.

Date on Market:

2026-01-05

San Diego Office for Lease - Mission Valley

With modern exterior improvements, sleek lobby finishes, and modern suite improvements, Mission Valley Crossroads at 404 Camino del Rio South offers remarkable office suites in San Diego, California. Mission Valley Crossroads is situated in a park-like setting in the heart of Mission Valley at the intersection of Interstate 8 and State Route 163. Available suites are ideal for Creative Office buildouts, with great floor-to-ceiling window lines offering amazing views in all directions, efficient floor plates and flexible suite sizes. In addition to the exceptional freeway visibility and identity, the proximity to the 163 Freeway and I-8 and limited on and off traffic presents commuters with quick freeway access. Employees enjoy onsite food and coffee options, and there are numerous other options in the surrounding area. This desirable Mission Valley address presents abundant dining, shopping, and entertainment amenities for before, during, and after work from the nearby retailers. Given the Class A finishes and the Class A location, Mission Valley Crossroads offers every office user the perfect environment in which to thrive.

Date on Market:

2026-01-13

La Jolla Retail for Lease

Property Type:

Multifamily

Date on Market:

2026-03-12

San Diego Retail for Lease - Downtown

Corner Retail Suite Available! Maximum visibility with a bite size retail space that includes building signage!

Property Type:

Multifamily

Date on Market:

2026-03-10

San Diego Retail for Lease - Kearny Mesa

MultiTenant Retail Center featuring overhead door loading and warehouse/production space. Building and monument signage with abundant parking just off the 163 provides and exception opportunity for a wide range of business types. Building is part of larger distribution/warehouse park of over 100,000 SF featuring dock high loading and overflow parking.

Date on Market:

2025-07-28

San Diego Flex for Lease - UTC

• ± 96,500 SF standalone flex/creative/R&D building on 6.55 acres in the heart of San Diego’s UTC innovation hub (± 18,000 SF of Office, ± 78,500 SF of Flex/Industrial) • Secure, campus-style setting with on-site amenities, surface parking, and controlled access • Highly efficient floor plates ideal for single-tenant HQ, design studio, R&D, or innovation lab uses • Amenities: on-site fitness center with showers and lockers, outdoor tennis and volleyball, creative and social spaces designed to inspire

Date on Market:

2026-01-16

San Diego Coworking for Lease - PB/Rose Canyon/Morena

Give life to your business in vibrant San Diego Join the diverse economy of California with a flexible and modern workspace in "America’s Finest City," San Diego. With a growing tech scene and thriving sectors in defense, international trade, biotechnology, and more, your business can fit in perfectly amongst the city’s successful market. Known for its vibrant culture, entertain clients with San Diego’s range of impressive live music venues, while your team enjoys the array of outdoor activities, like hiking and surfing, in their spare time. If you’re looking for a bite to eat, take your lunch break at one of the local restaurants on Morena Blvd and Ingulf St. Stay well connected from 2437 Morena Blvd with San Diego International Airport approximately 6.8 miles away. Visit the rest of the city via Morena Bl & Ingulf St Bus Stop, just a two-minute walk from your office space, or catch a train from Clairemont Drive Light Rail Station, only a three-minute walk away. Welcome clients to your large, fully furnished conference rooms and present with confidence using video conferencing technology. The business-grade WiFi will keep your work schedule productive, and the fully stocked kitchens mean you can enjoy a well-deserved break with a hot drink. Whether you’re looking to host guests or find a modern space for your team, 2437 Morena Blvd will help you do just that. Find a place to thrive at Regus 2437 Morena Blvd: • Professional Offices: Elegant office space equipped with modern furniture and amenities, easily scalable for individual professionals or entire teams. Move into a turnkey office, pay by day, or custom tailor a unique suite to accelerate organizational success. • Community: Work wherever you need to be and discover a dynamic mix of businesses and like-minded individuals. Regular networking and personal growth events and sociable workspaces foster collaboration and open new opportunities for your business. • Virtual Workspace: Build your presence anywhere in the world with a new virtual address. Whether simply to forward mail, hold a meeting, or even answer calls, Regus’ virtual offices have the services you need. • Collaboration: Host a meeting in every major city in the world and impress local clients with industry-leading technologies in one of the fully serviced meeting spaces. There is a room for every need with day-of booking for anything from private conference rooms to inspiring training spaces. • Join the Club: Regus’ thriving global network of beautifully designed offices provides the flexibility to work anywhere and everywhere. Reserve space on the move via the Regus app and get to work from any of the business lounges, dedicated desks, or your own private office. All images shown in this listing belong to Regus’ locations but may not correspond to this specific center.

Property Type:

Office

Date on Market:

2026-01-14

San Diego Retail for Lease - Downtown

• ±3,163 SF _ 1,859 SF available for lease, can combine for a total of ±5,022. • Situated in the East Village, Downtown’s fastest growing neighborhood, with over 7,000 units within 4 blocks of site • Adjacent to the new Park & Market development which will include UCSD’s 66,000 SF extension campus and 426 residential units • Close proximity to PETCO Park, the Convention Center, Gaslamp Quarter and the San Diego Central Library • Easy access to the I-5, 163 and 94 freeways • Nearby tenants include RoVino the Foodery, Starbucks, Cowboy Star, Lotus Thai Cuisine, Nekter Juice Bar, Tavern Bowl, The Kebab Shop, Half Door Brewing Co. • 2 public parking structures and multiple surface lots within 3 blocks

Property Type:

Multifamily

Date on Market:

2023-10-24

San Diego Office/Retail for Lease - Uptown East

Introducing "The Ken Community Suites", a complete restoration of the historic Ken Theatre in Kensington. The dynamic interior design perfectly combines the history of the Ken Theatre with newer contemporary design features. High ceilings, skylights, and dozens of new window openings suffuse the space with light and airy atmosphere, while exposed bow trusses and a historic marquee signage pay homage to the history of the complex. The Ken Community Suites will consist of 4 - 8 individual suites, ideal for creative office, holistic medical, small retail, or a variety of other users. Excellent building signage available. Suites for lease as early as December 2025.

Property Type:

Retail

Date on Market:

2025-08-15

San Diego Retail for Lease - Uptown West/Park West

Date on Market:

2025-06-30

San Diego Retail for Lease - Downtown

o Expansive patio space offering prime outdoor dining in one of San Diego’s most vibrant neighborhoods. o Modern, clean design o Located within San Diego’s largest farmers market, held twice a week, drawing thousands of visitors. o Unparalleled branding opportunity in one of the city's busiest tourist and dining districts, with the ability to host large events on the Piazza della Famiglia. o Prime walkable location, steps from the marina, Waterfront Park, USS Midway, and a short drive to the Gaslamp Quarter and San Diego Convention Center.

Property Type:

Multifamily

Date on Market:

2025-03-10

San Diego Retail for Lease - Downtown

Property Type:

Multifamily

Date on Market:

2025-01-09

San Diego Office for Lease - Downtown

Date on Market:

2026-02-25

La Jolla Office, Office/Retail for Lease

1218–1224 Prospect Street offers a rare opportunity to work steps from the ocean in the heart of La Jolla Village. The property features bright office suites with expansive coastal views and easy access to nearby restaurants, cafes, and boutique retail. This location provides a relaxed coastal setting with all the conveniences of a walkable village, creating an ideal environment for professionals who value both productivity and quality of life. Parking included in the garage next door.

Date on Market:

2025-11-18