131 Lofts for Lease in San Diego, CA, USA

Bonita Office for Lease - Chula Vista

Office suites, many with golf course/walking trail views in the highly desirable Bonita Valley. Excellent freeway access to 54 & 805. The building is serviced by an elevator and has ample parking. The building is located on Chula Vista Golf Course/Walking Trail.

Date on Market:

2025-12-05

San Diego Office for Lease - Mission Valley

Mission Valley offers the accessibility of a central business district with ample parking and world class amenities. Arterial freeways blanket Mission Valley and provide easy access to employers from population nodes across the region. Mission Valley has a vibrant community and is positioned to be the new business hub of San Diego.

Date on Market:

2025-11-20

San Diego Office for Lease - PB/Rose Canyon/Morena

3565 Del Rey St is Located adjacent to I-5 providing excellent freeway access and visibility. Fiber is available to the building as well as signage.

Date on Market:

2026-01-13

San Diego Office, Retail for Lease - Downtown

The Louis Bank of Commerce is one of San Diego’s most ornate commercial structures. The four-story Baroque Revival building was constructed in 1888 in the lively Gaslamp Quarter neighborhood. Punctuated by two rising towers, this landmark property possesses so many Victorian architectural features that it has been dubbed "The Queen of the Gaslamp." As the first granite building in San Diego, this building has housed everything from fortuneteller Madame Cora's Golden Poppy Hotel brothel and Ratner's Electric to the creative offices and restaurants that are found there today. Original hardwood floors, high ceilings, and exposed brick walls are hallmarks of the fully restored Louis Bank of Commerce building. Experience private elevator access to all floors, offering modern and efficient layouts that receive an abundance of natural light throughout the workday. Turnkey, fully furnished suites are available with flexible terms and quick, no-hassle move-ins. Additionally, the recently renovated fourth floor presents ideal office accommodations for creative technology companies. Join a diverse tenant mix that includes professional and creative offices. Located in the heart of downtown, the Louis Bank of Commerce provides convenient proximity to Horton Plaza Park, the San Diego Convention Center, support services, and more.

Date on Market:

2026-01-21

San Diego Office, Office/Medical for Lease - Rancho Bernardo

Prime location, Two story Medical or Office Space for lease with wrap around Balcony. Located in the Heart of Downtown Rancho Bernardo, on Bernardo Center Drive. Situated between two busy signalized intersections, and directly across the street from the Plaza and Towne Center retail shopping centers including Vons, CVS, banking, restaurants, coffee shops, U.S. Post Office, UPS, specialty shops, and services. Fed-Ex and On Trac boxes on site. The Marriott Hotel and scenic Webb Lake Park are adjacent. Easy access to freeway 1-15, with excellent parking available. Elevator Served, 24/7 key card access, On Site Management. Beautifully renovated Common areas and Restrooms.

Date on Market:

2025-09-17

National City Multiple Space Uses for Lease

Southport Industrial Park is a 297,533 SF multi-tenant industrial park with suites ranging from 829 RSF to 24,400 RSF. Numerous on-site retail amenities featuring In-N-Out Burger & Denny’s. Walking distance to 24th Street Trolley Station. Located within HubZone & Enterprise Zone. Ten minutes to the Mexico Border crossing, San Diego International Airport and Downtown San Diego.

Date on Market:

2026-01-30

Solana Beach Office for Lease - North Beach Cities

Garden Office building with lots of glass, close to many restaurants with fast access to I - 5.

Date on Market:

2025-09-19

San Diego Multiple Space Uses for Lease - Downtown

Date on Market:

2024-07-19

San Diego Flex for Lease - Mira Mesa/Miramar

Space is available Now. All square footage is ground floor. Short term deals (1yr minimum) can be considered on a case by case basis. Remodel Is complete, New LVP flooring on the entrance and offices, new Epoxy paint resin finish throughout the remainder of the space. Approximately 3,400 SF FLEX/Office space and warehouse. New LED lighting throughout/new flooring throughout 2 Skylights 4'x8' 2 Man Doors Two bathrooms ADA Compliant Two ground level (10' x12' ) truck doors 20' clear height inside the warehouse Wired for an alarm. AC in office space. Secured Gated yard in the back. Parking for up to ten vehicles, plenty of off street parking as well. City of San Diego IL-2-1 zoning 800 amp 120/208 3 phase 4 wire power

Date on Market:

2023-07-12

San Diego Office for Lease - Mission Valley

3636 CAMINO DEL RIO NORTH IS A 28,551 SF, TWO STORY PROFESSIONAL OFFICE BUILDING LOCATED IN CENTRAL MISSION VALLEY. THE PROPERTY FEATURES TWO ENTRANCES FOR EASY ACCESS THROUGHOUT. SUITES INCLUDE UNRESERVED ONSITE PARKING AT A RATIO OF 2.9 PER 1,000 SF LEASED. ALSO INCLUDED IS VISITOR PARKING AND AN ELEVATOR ONSITE. CLIENTS AND EMPLOYEES WILL ENJOY BEING ONLY MINUTES FROM THE RESTAURANT AND RETAIL AMENITIES OF MISSION VALLEY. DON’T MISS OUT ON THE PROFESSIONAL OFFICE SPACES AVAILABLE AT 3636 CAMINO DEL RIO NORTH.

Date on Market:

2025-10-09

San Diego Office for Lease - PB/Rose Canyon/Morena

• Centrally Located Professional 3-Story Office Building • Across the Street from Morena/Linda Vista Trolley Station (View Link) • Close Proximity to New Tecolote Blue Line Trolley to UCSD/UTC (View Link) • One Minute Access to Interstate 5 & 8 Freeways • Window-Lined Office with Amazing View of Mission Bay and Sea World • Elevator Served • 24/7 Access with Direct SDGE and Individually Controlled HVAC • Parking Ratio: Up to 3.6/1,000 SF Available • Garages Available for $250/Month - Contact Agent for Details • Lease Rates Starting At: $2.25/SF + Separately Metered Utilities - Includes three time per week janitorial

Date on Market:

2025-06-19

San Diego Flex for Lease - Sorrento Valley

Just south of the merge with easy access to I805 and I5.

Date on Market:

2025-07-14

San Diego Flex, Industrial for Lease - Sorrento Valley

La Jolla Sorrento Business Park offers a combination of office, warehouse and lab spaces.

Date on Market:

2025-11-10

San Diego Office, Retail for Lease - Downtown

Terrific location on 4th Avenue in the Gaslamp District. Two blocks from Petco Park, San Diego Convention Center, and Campus at Horton. Dozens of restaurants, cafes, and bars within a 5 block radius. Offices feature quality laminate flooring, abundant natural light, glassed offices and conference rooms, private restrooms and air conditioning. Secure entrance with dial in directory. 24/7 building access. Monthly garage parking available in nearby parking structures.

Date on Market:

2024-12-23

San Diego Office for Lease - Kearny Mesa

Date on Market:

2025-01-31

San Diego Office/Retail, Retail for Lease - PB/Rose Canyon/Morena

Retail, Medical, and Office Suites AVAILABLE Across from Home Depot, Sprouts, and Target DO NOT CALL! - INQUIRE VIA EMAIL OR THROUGH THE WEBSITE ONLY Due to the amount of spam calls, direct inquiries via the website are preferred Current Opportunities: **** Turn Key Medical Suite up to 4,356sf **** **** High Visibility Office/Retail Suites Available **** Ample Parking, Signalized Intersections, Excellent Tenant Mix Tesla Superchargers onsite High Visibility Retail & Office Center at signalized intersection on Genesee Competitive Lease Rates! Flexible Space Options! National Co-Tenants +/-400 Parking Spaces Situated in Major Retail Area 70,781sf of Total Retail/Office Well situated storefronts/suites Strong Area Demographics BUSY SHOPPING AREA with National Retailers Just off of Balboa & Genesee Excellent tenant mix in the area: Target Marshalls Walgreens, Rite Aid, & CVS Home Depot Pep Boys, O' Reilly, & Auto Zone Sprouts, Vons, & Albertsons Kohl's Bank of America & Wells Fargo The Habit Burger Grill and Much More! Traffic & Demographic Information: Exclusive Listing - Contact Brokers for Details and Showings DO NOT CALL! - INQUIRE VIA EMAIL OR THROUGH THE WEBSITE ONLY Due to the amount of spam calls, direct inquiries via the website are preferred

Date on Market:

2025-11-13

San Diego Office for Lease - Mission Valley

Two story office building with prime street frontage and central mission valley location. Ample parking, close proximity to public transit and highway 8 and highway 15, Kaiser Hospital, Home Depot, SDSU, Qualcomm Stadium, etc. Available now visit www.eldpinc.com for more information.

Date on Market:

2026-01-15

San Diego Office for Lease - Old Twn/S Arena/Pt Loma

Date on Market:

2025-04-29

San Diego Coworking for Lease - Downtown

Featuring a prominent location in the Downtown Financial District and adjacent to the historic Gaslamp Quarter, this 1913 building has been renovated to offer the latest amenities, including a rooftop deck and direct fiber internet. Here you will find six floors of state-of-the-art private offices and office suites that can accommodate teams of one to 50 people, bike storage, and the best coworking space in San Diego. Located at the heart of San Diego’s bustling Financial District, Expansive ’s Sixth Ave. building offers outstanding accessibility to the restaurants, hotels, and nightlife of the popular Gaslamp and Little Italy neighborhoods. Easy access to I-5 and State Route 163, while the 5th Ave. light rail station less than a block away connects clients with greater San Diego.

Property Type:

Office

Date on Market:

2024-10-11

San Diego Office/Retail, Retail for Lease - Downtown

This is a beautiful 1910 era historic specialty building. For many years this building has served as home for many of San Diego's finest jewelry manufacturers, wholesalers, retailers and repair shops. This building is perfect for those in the jewelry trade, having an average 90% occupancy rate, ample parking and a great location on the edge of the Gaslamp District. This space could also be a great location for antique dealers. Plenty of paid parking on-site and in area. At the corner of 6th and E, conveniently located two blocks from Horton Plaza and near the new downtown ballpark. Easy access to freeways. Within short walking distance to the Trolley, Courthouse, Main Library and the Post Office.

Date on Market:

2026-01-05

San Diego Office for Lease - Mission Valley

With modern exterior improvements, sleek lobby finishes, and modern suite improvements, Mission Valley Crossroads at 404 Camino del Rio South offers remarkable office suites in San Diego, California. Mission Valley Crossroads is situated in a park-like setting in the heart of Mission Valley at the intersection of Interstate 8 and State Route 163. Available suites are ideal for Creative Office buildouts, with great floor-to-ceiling window lines offering amazing views in all directions, efficient floor plates and flexible suite sizes. In addition to the exceptional freeway visibility and identity, the proximity to the 163 Freeway and I-8 and limited on and off traffic presents commuters with quick freeway access. Employees enjoy onsite food and coffee options, and there are numerous other options in the surrounding area. This desirable Mission Valley address presents abundant dining, shopping, and entertainment amenities for before, during, and after work from the nearby retailers. Given the Class A finishes and the Class A location, Mission Valley Crossroads offers every office user the perfect environment in which to thrive.

Date on Market:

2026-01-13

San Diego Flex for Lease - UTC

• ± 96,500 SF standalone flex/creative/R&D building on 6.55 acres in the heart of San Diego’s UTC innovation hub (± 18,000 SF of Office, ± 78,500 SF of Flex/Industrial) • Secure, campus-style setting with on-site amenities, surface parking, and controlled access • Highly efficient floor plates ideal for single-tenant HQ, design studio, R&D, or innovation lab uses • Amenities: on-site fitness center with showers and lockers, outdoor tennis and volleyball, creative and social spaces designed to inspire

Date on Market:

2026-01-16

San Diego Coworking for Lease - PB/Rose Canyon/Morena

Give life to your business in vibrant San Diego Join the diverse economy of California with a flexible and modern workspace in "America’s Finest City," San Diego. With a growing tech scene and thriving sectors in defense, international trade, biotechnology, and more, your business can fit in perfectly amongst the city’s successful market. Known for its vibrant culture, entertain clients with San Diego’s range of impressive live music venues, while your team enjoys the array of outdoor activities, like hiking and surfing, in their spare time. If you’re looking for a bite to eat, take your lunch break at one of the local restaurants on Morena Blvd and Ingulf St. Stay well connected from 2437 Morena Blvd with San Diego International Airport approximately 6.8 miles away. Visit the rest of the city via Morena Bl & Ingulf St Bus Stop, just a two-minute walk from your office space, or catch a train from Clairemont Drive Light Rail Station, only a three-minute walk away. Welcome clients to your large, fully furnished conference rooms and present with confidence using video conferencing technology. The business-grade WiFi will keep your work schedule productive, and the fully stocked kitchens mean you can enjoy a well-deserved break with a hot drink. Whether you’re looking to host guests or find a modern space for your team, 2437 Morena Blvd will help you do just that. Find a place to thrive at Regus 2437 Morena Blvd: • Professional Offices: Elegant office space equipped with modern furniture and amenities, easily scalable for individual professionals or entire teams. Move into a turnkey office, pay by day, or custom tailor a unique suite to accelerate organizational success. • Community: Work wherever you need to be and discover a dynamic mix of businesses and like-minded individuals. Regular networking and personal growth events and sociable workspaces foster collaboration and open new opportunities for your business. • Virtual Workspace: Build your presence anywhere in the world with a new virtual address. Whether simply to forward mail, hold a meeting, or even answer calls, Regus’ virtual offices have the services you need. • Collaboration: Host a meeting in every major city in the world and impress local clients with industry-leading technologies in one of the fully serviced meeting spaces. There is a room for every need with day-of booking for anything from private conference rooms to inspiring training spaces. • Join the Club: Regus’ thriving global network of beautifully designed offices provides the flexibility to work anywhere and everywhere. Reserve space on the move via the Regus app and get to work from any of the business lounges, dedicated desks, or your own private office. All images shown in this listing belong to Regus’ locations but may not correspond to this specific center.

Property Type:

Office

Date on Market:

2026-01-14

San Diego Retail for Lease - Downtown

• ±3,163 SF _ 1,859 SF available for lease, can combine for a total of ±5,022. • Situated in the East Village, Downtown’s fastest growing neighborhood, with over 7,000 units within 4 blocks of site • Adjacent to the new Park & Market development which will include UCSD’s 66,000 SF extension campus and 426 residential units • Close proximity to PETCO Park, the Convention Center, Gaslamp Quarter and the San Diego Central Library • Easy access to the I-5, 163 and 94 freeways • Nearby tenants include RoVino the Foodery, Starbucks, Cowboy Star, Lotus Thai Cuisine, Nekter Juice Bar, Tavern Bowl, The Kebab Shop, Half Door Brewing Co. • 2 public parking structures and multiple surface lots within 3 blocks

Property Type:

Multifamily

Date on Market:

2023-10-24