129 Lofts for Lease in South Carolina, USA

Rock Hill Office, Retail for Lease - York County

Unique by design with transformative renovations, The Thread at 220 W White Street is a creative destination for the community to thrive in a vibrant live-work-play environment. This one-of-a-kind 400,000-square-foot adaptive reuse development plans to preserve the historical elements of the original textile mill and warehouse building while creating a modern feel. The Thread offers approximately 340,000 square feet of creative Class A office space with spacious and market-leading 135,000-square-foot floor plates where businesses have plentiful room to grow and flourish, perfect for a headquarters location. Full-floor and multi-tenant options are available. Flexible space from tenant lounges to collaboration areas allows for changing scenery throughout the work day or accommodating group breakouts. Each floor features impressive 18-foot ceiling heights and abundant natural lighting. Tenants will enjoy the signage opportunities, plethora of walkable amenities, ample parking, and the new storyline trail greenway project running directly through the development. The Freight Yard at The Thread hosts an on-site food truck court and music/events venue, promoting socializing and connecting within the community. On the ground level of this three-story building, there will be approximately 60,000 square feet of retail space. Centrally located in the heart of Knowledge Park, The Thread sits at the confluence of the two most bustling parts of Rock Hill, Winthrop University, and the heart of Downtown. Adjacent to the development is the Rock Hill Sports and Event Center. Positioned in one of the most pedestrian-friendly and dynamic submarkets, The Thread is surrounded by multiple multifamily developments, residential neighborhoods, and numerous walkable amenities, including breweries, coffee shops, retailers, shopping options, and other services. Take advantage of an exceptional opportunity to be part of one of the most unique creative office and mixed-use developments in a sought-after destination in Rock Hill at The Thread.

Date on Market:

2025-10-28

Columbia Office, Office/Medical for Lease - St Andrews

Executive One Center at 3790 Fernandina Road offers well-maintained office space in Columbia's sought-after St. Andrews submarket. This three-story, 27,343-square-foot office is a beautiful, stately building boasting a brick façade and a welcoming, fully renovated lobby. Various move-in-ready suites are available, ranging in square footage to best fit business needs. Spec suite opportunities are also available on the first floor. Building features include ample parking, restrooms on each floor, an elevator, and handicapped access. Nearby amenities include Columbiana Station, Harbison Court, Columbiana Centre, and Ashland Park Shopping Center. On the second floor, Suite 203 offers two private offices, large open space, a kitchenette, among the total 2,291 square feet. On the third floor we have two large suites that are move in ready. Suite 301 has 2235 SF and has 8 offices, reception area, fax/copier bullpen and kitchenette. Suite 303 has 7-8 private offices, executive corner suite, huge reception area, large conference room and kitchenette. Strategically located in a highly visible area, Executive One Center provides premium frontage along the heavily trafficked Interstate 26, with exposure to over 123,760 daily drivers. Signage opportunities are available, including the exterior LED monument sign. Executive One Center is incredibly accessible to the Interstate 26 and Interstate 20 Interchange, one mile away, and Downtown Columbia, 10 minutes away. Several factors, including low business and living costs, local tax incentives, and a central location near major interstates, have attracted various businesses to the area. Well maintained with incredible visibility, Executive One Center is primed to offer ideal office space.

Date on Market:

2025-07-16

Mount Pleasant Coworking for Lease - East Islands/Mt Pleasant

Inspiring building designed to impress Located in the Charleston County commercial corridor, 1240 Winnowing Way is in an inspiring building designed to impress. It's also conveniently situated for access to beautiful beaches and historic Charleston. When it comes to first impressions, the four storey building works hard with an exterior of glass and high quality lobby. And for escaping work the centre has a lounge area and enjoys a prominent location close to the town's restaurants and amenities.

Property Type:

Multifamily

Date on Market:

2025-04-28

Beaufort Medical for Lease

This 60,440 square foot medical office building is located at 300 Midtown Drive in Beaufort, South Carolina. The property has a robust tenant roster including Select Physical Therapy Beaufort and Beaufort Memorial Lowcountry Medical Group Primary Care. The office is located 10 miles from Beaufort Memorial Hospital.

Property Type:

Office

Date on Market:

2023-04-10

Greenville Retail for Lease - Pelham/I-85

Establish a presence in one of Greenville’s most active and affluent corridors with this high-visibility suite offered via sublease. Pelham Hills Shopping Center is a prominent fixture of a larger mixed-use node at the crossing of Pelham Road and Interstate 85. Tenants will be joining a premier mix of daily traffic drivers in the vicinity, such as Walmart Supercenter, Topgolf, Lowes Foods, CVS, and dozens of local and national brand restaurants. The center offers ample parking and monument signage to capitalize on exposure. Suite B spans 1,250 square feet, and its adaptable layout is well-positioned for retail, office, medical, or professional services. It features a spacious interior with minimal column blockage to accommodate a variety of configurations. The suite also has sufficient plumbing hook-ups for water-intensive uses, such as specialty dental practices or small restaurants. High-profile residential and commercial hubs in the immediate area showcase the density of demand drivers. The Thornblade Country Club, Michelin’s North American headquarters, the Greenville Marriott, several large-scale industrial facilities, and over 2,400 apartment units are within a mile of Pelham Hills, just some of the locational elements that form a built-in consumer base. Affluent households are concentrated in this area, and the number continues to rise, with estimates calling for an annual household growth rate of 2% through 2029 within a 3-mile radius. These residents are naturally drawn to this area due to the aforementioned destinations and its strategic location along Interstate 85, making Pelham Hills Shopping Center a prime stop for commuter traffic and leisurely local visitors.

Date on Market:

2025-12-06

Greenville Office for Lease - West End

504 Rhett Street is a ±20,246-square-foot building offering two suites for lease: Suite 205 on the upper level, ±2,035 SF (available July 1, 2026) and Suite 110 on the lower level, ±2,626 SF at a lease rate of $34.00/SF.  Situated in the heart of Greenville’s West End, the building is just one block from Fluor Field and a short walk to South Main Street, surrounded by residential, retail and office spaces that create a vibrant, active environment. Popular destinations such as Unity Park, Falls Park on the Reedy and the Swamp Rabbit Trail are all within walking distance, offering convenience and connectivity. The property provides desirable features including exterior signage, an outdoor patio, a fitness center and on-site showers—ideal for businesses seeking modern amenities in a boutique setting. Fully renovated in 2016, the building includes HVAC units from 2016 and a TPO membrane roof installed in 2014, ensuring quality infrastructure for tenants.

Date on Market:

2026-01-14

Daniel Island Office for Lease

Four Corners Plaza is located in the master-planned community of Daniel Island, is pedestrian friendly, and offers abundant nearby amenities. Ample on-site parking is available behind the building to accommodate both cars and golf carts

Date on Market:

2026-01-12

Spartanburg Office/Retail for Lease - North Side/Rt 9 Corridor

7931 Valley Falls Rd offers a rare combination of modern design, calm surroundings, and everyday convenience—an ideal setting for business owners who want their workspace to feel just as professional and refined as the services they provide. This thoughtfully designed, single-story office building features private suites with access to a shared reception lobby and conference room, creating a polished, client-ready experience without the cost or complexity of a large standalone office. From the moment clients arrive, the space makes an impression—distinctive architectural columns at the entrance, clean lines, and warm natural materials set the tone for a confident, established business presence. The building is surrounded by a spacious, beautifully finished parking lot with custom concrete detailing, offering easy drive-in and drive-out access for both tenants and clients. Large windows throughout the building allow abundant natural light, enhancing the interior with an open, welcoming feel while maintaining privacy and comfort. Inside, the space blends luxury wood finishes and modern accent lighting with a clean, professional layout. The atmosphere feels calm and intentional—ideal for client meetings, consultations, and focused work. Shared common areas include a stylish reception lobby, conference/meeting space, and two ADA-accessible restrooms (men’s and women’s). The property is fully climate-controlled and designed to be move-in ready. Zoned County C-Commercial (outside city limits), the property is well-suited for professional offices, consulting, therapy or wellness practices, boutique beauty services, and other appointment-based, client-facing businesses. The layout offers flexibility while maintaining a high-end, cohesive look throughout the building. Despite the peaceful setting, the location is exceptionally convenient—just minutes from I-85, I-585, and Highway 176, providing quick access across Spartanburg and surrounding areas. Strong visibility from Valley Falls Rd ensures your business is easy to find, while the setting remains quiet and composed. This is a space designed for business owners who value presentation, ease, and longevity—a place where clients feel comfortable, and professionals feel proud to welcome them.

Property Type:

Office

Date on Market:

2026-01-07

Charleston Retail for Lease - Downtown Charleston

Position your brand in the heart of Charleston’s iconic historic district with this premier retail opportunity at the corner of Market and Church Streets. Located steps from renowned dining, boutique shopping, and cultural landmarks, this property benefits from exceptional foot traffic and affluent demographics, with average household incomes exceeding $125,000 within a one-mile radius. The surrounding area is a magnet for both locals and tourists, ensuring consistent exposure and engagement. This corner unit has a loft for storage and/or office space. Sublease expiring 7/31/2032. Net sublease; Tenant to pay pro rata share of taxes and insurance. Available immediately once current tenant vacates. Security deposit of $7,827 due at sublease execution.

Date on Market:

2026-01-06

Greenville Office for Lease - West End

Amazing office location directly in the Central Business District on the West End of downtown Greenville. One block off of Main St, this historic firehouse offers amazing large timber framing and open spaces for maximum versatility. Great access to all Greenville offers, including Fluor Field (Boston Red Sox Affiliate Baseball Team), Unity Park and the Swamp Rabbit Trail, hotels, apartment homes and award winning restaurants! New ownership is making approximately 2,200sf of office/meeting space available in Q2-2026. Office will be accessible through private front door, Rhett St facing, or through common entrance at main building entrance. Parking available. Future plans for expanded private office suites, storage and gym/exercise area amenities on the ground floor anticipated in 2026. Contact Mark Foster, markfoster@kw.com or 864-275-1658 for additional details.

Date on Market:

2025-12-22

Greenville Retail for Lease - West End

Wonderful ground floor space on Main Street in Greenville, SC Pedestrian friendly with outdoor sidewalk seating, if desired.

Date on Market:

2025-12-11

Columbia Retail for Lease - Northeast Columbia

Metal roof structurally repaired and replaced fall of 2025. 5 bay garage of approximately 3,360 SF (small office w loft and bay area). Long established and respected proprietor of 30 years recently retired. Loyal following at the location. Frontage on Two Notch Road in affluent northeast Columbia. Highly trafficked stretch of Two Notch Road between Sparkleberry and Clemson Roads near The Village at Sandhills.

Date on Market:

2025-12-11

Easley Office for Lease - Outlying Pickens County

Elevated over Hwy 153 in Pickens County SC. Free standing building with ample onsite parking. Great synergistic atmosphere.

Date on Market:

2025-12-06

West Columbia Flex for Lease - Cayce/West Columbia

Located in the Overlook Business Center, 104 Vantage Point Drive offers a premier flex solution in West Columbia’s highly competitive industrial market. This property combines Class A office space with high-bay warehouse functionality, delivering an ideal environment for businesses seeking both professional presence and operational efficiency. The office component spans over 12,000 SF, featuring executive offices, conference rooms, and training areas, while the warehouse provides 18-foot clear height, one dock-high door, and one drive-in door for versatile loading options. The site includes a 3,000 SF fenced outdoor storage area and a 1,000 SF lean-to, complemented by 50 surface parking spaces for staff and visitors. Situated just one mile from Interstate 26 and two miles from Interstate 77, the property ensures seamless regional connectivity, while Columbia Metropolitan Airport is only 6.5 miles away for convenient air freight access. Surrounded by major distribution hubs, including Amazon, Husqvarna, and Lowe’s, this location positions tenants at the center of a thriving logistics network.

Date on Market:

2025-12-02

Irmo Office for Lease - Dutch Fork/Irmo

The office has had numerous customers to tenant businesses complimenting on its curb appeal due to the courtyard with blooming azalea's, bubbling fountain, palm tree and just overall welcoming appeal. There is a front, side and rear door for easy access. The office also has a large walk-up attic for added storage.

Date on Market:

2025-12-01

Hilton Head Island Office for Lease

Nestled off of New Orleans Road between Pope Avenue and Sea Pines Circle, the location is minutes away from everything the South End of Hilton Head has to offer. This includes its world renowned beaches and bike paths as well as multiple retail shops and restaurants, Celebration Park, Coligny Plaza, Sea Pines, and Shipyard. 1 Corpus Christi Place has easy access, abundant parking, and a nice mix of adjacent occupants which includes attorneys, financial, real estate, and professional pictures.

Date on Market:

2025-11-29

Beaufort Flex for Lease

Property Address: 164 Robert Smalls Pkwy., Beaufort, SC 29902 County: Beaufort Parcel Tax ID: R100-029-000-0166-0000 Lease Rate: $15 psf NNN (Net fees) $1.1 psf. $24,062.50 a/mo. Base rent. $1,764.58 a/mo. NNN Fees Property Size: 47,480+-sf Acres: 1.09 Acres Building Size SF: 19,250+-sf Retail SF: 12,650+-sf including Office SF: 522+-sf Warehouse SF: 6,615+-sf Bathrooms: 2 (Two) ADA Location: Highway 170/ RSP Business Corridor Zoning: T5-UC/RMX (Commercial) Date of Construction: 1976 Date of Renovation: New front brick façade, sealed floor 2025 Property Type: Retail/ Warehouse/ Flex

Date on Market:

2025-11-26

Mount Pleasant Retail for Lease - East Islands/Mt Pleasant

Come be a part of the Iron Gate Plaza boutique shopping experience! It is quaint local and there is great driving traffic as well as walking traffic from the Comfort Suites Hotel located in the plaza. Excellent visibility located near the corner of Hungryneck Boulevard and the Isle of Palms Connector. Professionally landscaped. Illuminated Monument Sign. 2400 sf. New Restroom. Double Glass Front Doors. Other tenants include Arthur Murray Dance Studio (coming soon), King Street Grille, Guadalajara Mexican Restaurant, TOAST All Day, Nick's German Kitchen, UPS, Atlantic Chiropractic, Any Lab Test Now, Haven Nails, Sweet Strength Personal Trainers and Salon Yvonne Nicole (just opened in a beautifully renovated end cap unit). Other businesses within the Plaza are Comfort Suites Hotel, Pipeline Surf Shop and White Horse Auto Wash. Presented to you by Shawn Howell O/A

Date on Market:

2025-11-25

Spartanburg Office, Retail for Lease - East Side

Position your business in one of Spartanburg’s most iconic destinations: Drayton Mills Marketplace, an award-winning adaptive reuse development blending history with modern convenience. Suite 101 offers ±8,785 SF of versatile space ideal for a restaurant, event venue, or creative concept. Suite 140B offers ±3,934 SF of space with an open layout and private office options suited for creative or professional use. The property’s Romanesque Revival architecture, exposed brick, and soaring ceilings create an authentic backdrop that resonates with today’s experiential retail and hospitality trends. Located just minutes from Downtown Spartanburg—one of the fastest-growing MSAs in the U.S.—Drayton Mills is a thriving live-work-play campus featuring 289 luxury loft apartments, boutique retail, fitness studios, and popular dining options. Guests and employees enjoy immediate access to the 32-mile Drayton Mills Trail, connecting the property to the broader Spartanburg community. Ample parking, walkable amenities, and steady foot traffic from over 500 residents make this an exceptional opportunity for operators seeking visibility and vibrancy. The surrounding area boasts strong demographics, with an average household income exceeding $70,000 within a 10-minute drive. Spartanburg’s growth trajectory, coupled with the property’s historic charm and modern infrastructure, positions Suite 101 as a premier choice for businesses looking to make a lasting impression.

Date on Market:

2025-11-25

Greer Retail for Lease - Rt 101 Corridor

Reedy River Retail at SVN | Palmetto is pleased to present ±11,900 SF of new construction multi-tenant retail space available at 1963 SC101 in Greer, SC. This development sits on ±3.33 acres in one of the Upstate’s fastest-growing corridors, offering excellent visibility and accessibility with full access on SC-101 and a secondary ingress proposed onto Rogers Bridge Road. The property benefits from strong traffic counts and proximity to national retailers, making it ideal for retail, medical, or office users seeking a prominent location in a high-demand market. The property will be delivered in Warm Grey Shell condition in 2026, featuring HVAC in place and flexible layout options ready for tenant-specific buildout. Key Highlights: Proposed Drive-thru endcap Available Lease Rate: ±$30–35/SF NNN Space Available: ±1,700–11,900 SF Traffic Count: ±27,000 VPD on SC-101 Parking: ±87 spaces (±3.64/1,000 SF)

Date on Market:

2025-11-14

Greenville Office/Retail for Lease - West Side Greenville

Positioned in the heart of Unity Park, one of Greenville’s most transformative urban developments, 25 Delano Drive offers a rare opportunity to lease ±5,000 square feet of flexible retail, restaurant, or office space in a high-visibility, high-traffic location. This property sits directly on the Swamp Rabbit Trail and across from The Commons, a popular mixed-use destination, making it ideal for businesses seeking strong foot traffic and community engagement. The space features exposed brick, garage doors, loft-style interiors, and a large adjacent outdoor patio, creating a dynamic environment for experiential retail, food and beverage, or creative office users. On-site parking adds convenience, while co-tenancy with Southern side Brewing, Southern side Bowling, and Soul Yoga enhances the site’s appeal to lifestyle-driven consumers. Unity Park itself spans 60 acres and includes greenways, playgrounds, splash pads, and event spaces, drawing thousands of visitors weekly. The surrounding area is a blend of residential, recreational, and commercial uses, with Fluor Field, Falls Park, and downtown Greenville all within walking distance. This location offers unmatched access to the city’s most vibrant districts and is ideal for operators looking to capitalize on Greenville’s continued growth and investment in urban placemaking.

Property Type:

Retail

Date on Market:

2025-10-22

Anderson Industrial for Lease - Anderson County

Date on Market:

2025-10-21

Charleston Retail for Lease - Downtown Charleston

59 Broad Street offers a rare opportunity to lease high-visibility retail/restaurant space in Charleston's iconic Broad Street corridor. Located within a three-story mixed-use building that will soon undergo exciting facade renovations, this suite offers exceptional foot traffic, historic charm, and proximity to some of downtown Charleston’s most sought-after dining, retail, and professional destinations. Ideal for an intimate restaurant, wine bar, coffee shop, etc; owner is willing to provide TIA to assist with the upfit cost for qualified operators. The building will feature an elegant façade with a folding door system so that the entire storefront can be opened up to Broad St on nice days. The interior offers a flexible layout ready to be tailored to a tenant’s specific needs. The first two floors, each just over 1600sf are connected by both elevator and rear stairwell, and allows operates a seamless two-story layout opportunity. Situated on one of the city’s most prestigious and walkable streets, 59 Broad provides a premier address with convenient access to nearby neighborhoods, government buildings, and tourist hubs.

Property Type:

Office

Date on Market:

2025-06-13

Sumter Flex for Lease

10,500 sq ft warehouse with 1,750 sq ft of office space, 3 restrooms, 1 breakroom, loading dock and 6 overhead doors. Currently occupied by M & M Auto until 12/1/2025. Property can be viewed M-F between 8:30 am - 5:30 pm; must contact office to schedule prior to viewing.

Date on Market:

2025-10-20