144 Lofts for Lease in South Carolina, USA

Rock Hill Office, Retail for Lease - York County

Unique by design with transformative renovations, The Thread at 220 W White Street is a creative destination for the community to thrive in a vibrant live-work-play environment. This one-of-a-kind 400,000-square-foot adaptive reuse development plans to preserve the historical elements of the original textile mill and warehouse building while creating a modern feel. The Thread offers approximately 340,000 square feet of creative Class A office space with spacious and market-leading 135,000-square-foot floor plates where businesses have plentiful room to grow and flourish, perfect for a headquarters location. Full-floor and multi-tenant options are available. Flexible space from tenant lounges to collaboration areas allows for changing scenery throughout the work day or accommodating group breakouts. Each floor features impressive 18-foot ceiling heights and abundant natural lighting. Tenants will enjoy the signage opportunities, plethora of walkable amenities, ample parking, and the new storyline trail greenway project running directly through the development. The Freight Yard at The Thread hosts an on-site food truck court and music/events venue, promoting socializing and connecting within the community. On the ground level of this three-story building, there will be approximately 60,000 square feet of retail space. Centrally located in the heart of Knowledge Park, The Thread sits at the confluence of the two most bustling parts of Rock Hill, Winthrop University, and the heart of Downtown. Adjacent to the development is the Rock Hill Sports and Event Center. Positioned in one of the most pedestrian-friendly and dynamic submarkets, The Thread is surrounded by multiple multifamily developments, residential neighborhoods, and numerous walkable amenities, including breweries, coffee shops, retailers, shopping options, and other services. Take advantage of an exceptional opportunity to be part of one of the most unique creative office and mixed-use developments in a sought-after destination in Rock Hill at The Thread.

Date on Market:

2025-10-28

Columbia Office, Office/Medical for Lease - St Andrews

Executive One Center at 3790 Fernandina Road offers well-maintained office space in Columbia's sought-after St. Andrews submarket. This three-story, 27,343-square-foot office is a beautiful, stately building boasting a brick façade and a welcoming, fully renovated lobby. Various move-in-ready suites are available, ranging in square footage to best fit business needs. Spec suite opportunities are also available on the first floor. Building features include ample parking, restrooms on each floor, an elevator, and handicapped access. Nearby amenities include Columbiana Station, Harbison Court, Columbiana Centre, and Ashland Park Shopping Center. On the second floor, Suite 203 offers two private offices, large open space, a kitchenette, among the total 2,291 square feet. On the third floor we have two large suites that are move in ready. Suite 301 has 2235 SF and has 8 offices, reception area, fax/copier bullpen and kitchenette. Suite 303 has 7-8 private offices, executive corner suite, huge reception area, large conference room and kitchenette. Strategically located in a highly visible area, Executive One Center provides premium frontage along the heavily trafficked Interstate 26, with exposure to over 123,760 daily drivers. Signage opportunities are available, including the exterior LED monument sign. Executive One Center is incredibly accessible to the Interstate 26 and Interstate 20 Interchange, one mile away, and Downtown Columbia, 10 minutes away. Several factors, including low business and living costs, local tax incentives, and a central location near major interstates, have attracted various businesses to the area. Well maintained with incredible visibility, Executive One Center is primed to offer ideal office space.

Date on Market:

2025-07-16

Mount Pleasant Coworking for Lease - East Islands/Mt Pleasant

Regus 1240 Winnowing Way is strategically located in Mount Pleasant, providing businesses with exceptional access to local government offices at Mount Pleasant Town Hall, ensuring compliance and streamlined operations. The proximity to East Cooper Medical Center enhances employee well-being, while the nearby Mount Pleasant Library supports research and community engagement. Nearby, the Coleman Boulevard and Old Village district offers a variety of retail, dining, and professional services, ideal for hosting clients or team outings. With convenient connections to major transport routes, this location offers seamless access to clients and decision-makers. Our flexible offices provide a professional environment ideal for attracting top talent, while coworking spaces foster collaboration and innovation. This prime spot ensures operational efficiency and cost-effectiveness, making it a smart choice for growing businesses. Find a place to thrive at Regus 1240 Winnowing Way: • Professional Offices: Elegant office space equipped with modern furniture and amenities, easily scalable for individual professionals or entire teams. Move into a turnkey office, pay by day, or custom tailor a unique suite to accelerate organizational success. • Community: Work wherever you need to be and discover a dynamic mix of businesses and like-minded individuals. Regular networking and personal growth events and sociable workspaces foster collaboration and open new opportunities for your business. • Virtual Workspace: Build your presence anywhere in the world with a new virtual address. Whether simply to forward mail, hold a meeting, or even answer calls, Regus’ virtual offices have the services you need. • Collaboration: Host a meeting in every major city in the world and impress local clients with industry-leading technologies in one of the fully serviced meeting spaces. There is a room for every need with day-of booking for anything from private conference rooms to inspiring training spaces. • Join the Club: Regus’ thriving global network of beautifully designed offices provides the flexibility to work anywhere and everywhere. Reserve space on the move via the Regus app and get to work from any of the business lounges, dedicated desks, or your own private office.

Property Type:

Multifamily

Date on Market:

2025-04-28

Beaufort Medical for Lease

This 60,440 square foot medical office building is located at 300 Midtown Drive in Beaufort, South Carolina. The property has a robust tenant roster including Select Physical Therapy Beaufort and Beaufort Memorial Lowcountry Medical Group Primary Care. The office is located 10 miles from Beaufort Memorial Hospital.

Property Type:

Office

Date on Market:

2023-04-10

Spartanburg Office/Retail for Lease - East Side

A rare opportunity to lease ±3,934 SF of office space in the historic Drayton Mills Marketplace. This is one of South Carolina’s most successful adaptive-reuse mixed-use communities. This flexible office suite sits within a vibrant live-work-play campus anchored by loft apartments, restaurants, retail, fitness, and community events. The space offers a bright, efficient layout with exposed brick, tall ceilings, and the character you expect in a restored textile mill. Ideal for teams seeking a creative environment with walkable amenities and direct access to the on-site trail system that connects through the property. Bull Realty SC License: 13327

Property Type:

Retail

Date on Market:

2026-02-27

Greenville Office/Retail for Lease - Greenville CBD

Prime Downtown Greenville Opportunity | 205 N. Laurens Street Positioned in the heart of downtown Greenville, 205 N. Laurens Street offers a rare opportunity to lease property in one of the city’s most active and walkable corridors. Located just steps from Main Street, Falls Park, restaurants, offices, hotels, and entertainment, this property benefits from exceptional visibility, strong pedestrian traffic, and long-term growth fundamentals. The building is ideally suited for professional office, boutique retail, service-based business, with flexibility that appeals to many. Surrounded by established businesses and ongoing downtown development, this location supports stable tenancy.

Property Type:

Office

Date on Market:

2026-02-24

West Columbia Office for Lease - Cayce/West Columbia

1904 Sunset Boulevard is a ±5,958-square-foot, four-unit professional office building constructed in 1995 and prominently positioned along the highly traveled Sunset Boulevard corridor in West Columbia. The property offers strong street visibility and direct access to one of the area’s primary commercial thoroughfares, with convenient connectivity to I-26, I-77, and I-20. Strategically located approximately one mile from Lexington Medical Center and well situated to serve both Lexington and Richland County markets, the building provides an established professional setting with ample on-site parking. Surrounded by national retailers, service providers, and dense residential neighborhoods, this location offers both accessibility and sustained traffic exposure in a mature commercial corridor.

Date on Market:

2026-02-24

Greer Retail for Lease - Greer/Taylors

Located at Greer City Park across from Hampton Inn and Parking Garage. Kitchen with large Dining Room and outside Covered Patio. One of the BEST spots in Downtown Greer! call Chuck for private viewing before it gets gone.

Date on Market:

2026-02-20

Greer Retail for Lease - Greer/Taylors

Beautiful building in front of Greer City Park and one block from Poinsett Street

Date on Market:

2026-02-20

North Charleston Flex for Lease

Date on Market:

2026-02-19

Chesnee Industrial for Lease - Upper Spartanburg County

Date on Market:

2026-02-11

Greenville Flex for Lease - West Side Greenville

Crescent Startup Community, a large-scale mixed-use Innovation District will provide a dedicated space for startups, entrepreneurs, and the development of innovative ideas and research. Crescent will sit on seven acres of land on Poinsett Highway and open in late Spring 2024 with the completion of Phase One, a 56,000 square foot adaptive reuse project. Phase Two will include 150,000 square feet of new build mixed-use space dedicated to innovation.

Property Type:

Office

Date on Market:

2026-02-09

Orangeburg Retail for Lease

Date on Market:

2026-02-07

Edgefield Office for Lease - Edgefield County

Date on Market:

2026-02-03

Charleston Retail for Lease - West Ashley

Date on Market:

2026-01-26

Greenville Office for Lease - Pettigru

Date on Market:

2026-01-22

Mount Pleasant Retail for Lease - East Islands/Mt Pleasant

Come be a part of the Iron Gate Plaza boutique shopping experience! It is quaint local and there is great driving traffic as well as walking traffic from the Comfort Suites Hotel located in the plaza. Excellent visibility located near the corner of Hungryneck Boulevard and the Isle of Palms Connector. Professionally landscaped. Illuminated Monument Sign. 2400 sf. New Restroom. Double Glass Front Doors. Other tenants include Arthur Murray Dance Studio (coming soon), King Street Grille, Guadalajara Mexican Restaurant, TOAST All Day, Nick's German Kitchen, UPS, Atlantic Chiropractic, Any Lab Test Now, Haven Nails, Sweet Strength Personal Trainers and Salon Yvonne Nicole (just opened in a beautifully renovated end cap unit). Other businesses within the Plaza are Comfort Suites Hotel, Pipeline Surf Shop and White Horse Auto Wash. Presented to you by Shawn Howell O/A

Date on Market:

2025-11-25

Daniel Island Office for Lease

Four Corners Plaza is located in the master-planned community of Daniel Island, is pedestrian friendly, and offers abundant nearby amenities. Ample on-site parking is available behind the building to accommodate both cars and golf carts

Date on Market:

2026-01-12

Spartanburg Office/Retail for Lease - North Side/Rt 9 Corridor

7931 Valley Falls Rd offers a rare combination of modern design, calm surroundings, and everyday convenience—an ideal setting for business owners who want their workspace to feel just as professional and refined as the services they provide. This thoughtfully designed, single-story office building features private suites with access to a shared reception lobby and conference room, creating a polished, client-ready experience without the cost or complexity of a large standalone office. From the moment clients arrive, the space makes an impression—distinctive architectural columns at the entrance, clean lines, and warm natural materials set the tone for a confident, established business presence. The building is surrounded by a spacious, beautifully finished parking lot with custom concrete detailing, offering easy drive-in and drive-out access for both tenants and clients. Large windows throughout the building allow abundant natural light, enhancing the interior with an open, welcoming feel while maintaining privacy and comfort. Inside, the space blends luxury wood finishes and modern accent lighting with a clean, professional layout. The atmosphere feels calm and intentional—ideal for client meetings, consultations, and focused work. Shared common areas include a stylish reception lobby, conference/meeting space, and two ADA-accessible restrooms (men’s and women’s). The property is fully climate-controlled and designed to be move-in ready. Zoned County C-Commercial (outside city limits), the property is well-suited for professional offices, consulting, therapy or wellness practices, boutique beauty services, and other appointment-based, client-facing businesses. The layout offers flexibility while maintaining a high-end, cohesive look throughout the building. Despite the peaceful setting, the location is exceptionally convenient—just minutes from I-85, I-585, and Highway 176, providing quick access across Spartanburg and surrounding areas. Strong visibility from Valley Falls Rd ensures your business is easy to find, while the setting remains quiet and composed. This is a space designed for business owners who value presentation, ease, and longevity—a place where clients feel comfortable, and professionals feel proud to welcome them.

Property Type:

Office

Date on Market:

2026-01-07

Charleston Retail for Lease - Downtown Charleston

Position your brand in the heart of Charleston’s iconic historic district with this premier retail opportunity at the corner of Market and Church Streets. Located steps from renowned dining, boutique shopping, and cultural landmarks, this property benefits from exceptional foot traffic and affluent demographics, with average household incomes exceeding $125,000 within a one-mile radius. The surrounding area is a magnet for both locals and tourists, ensuring consistent exposure and engagement. This corner unit has a loft for storage and/or office space. Sublease expiring 7/31/2032. Net sublease; Tenant to pay pro rata share of taxes and insurance. Available immediately once current tenant vacates. Security deposit of $7,827 due at sublease execution.

Date on Market:

2026-01-06

Greenville Office for Lease - West End

Amazing office location directly in the Central Business District on the West End of downtown Greenville. One block off of Main St, this historic firehouse offers amazing large timber framing and open spaces for maximum versatility. Great access to all Greenville offers, including Fluor Field (Boston Red Sox Affiliate Baseball Team), Unity Park and the Swamp Rabbit Trail, hotels, apartment homes and award winning restaurants! New ownership is making approximately 2,200sf of office/meeting space available in Q2-2026. Office will be accessible through private front door, Rhett St facing, or through common entrance at main building entrance. Parking available. Future plans for expanded private office suites, storage and gym/exercise area amenities on the ground floor anticipated in 2026. Contact Mark Foster, markfoster@kw.com or 864-275-1658 for additional details.

Date on Market:

2025-12-22

Columbia Retail for Lease - Northeast Columbia

Metal roof structurally repaired and replaced fall of 2025. 5 bay garage of approximately 3,360 SF (small office w loft and bay area). Long established and respected proprietor of 30 years recently retired. Loyal following at the location. Frontage on Two Notch Road in affluent northeast Columbia. Highly trafficked stretch of Two Notch Road between Sparkleberry and Clemson Roads near The Village at Sandhills.

Date on Market:

2025-12-11

Easley Office for Lease - Outlying Pickens County

Elevated over Hwy 153 in Pickens County SC. Free standing building with ample onsite parking. Great synergistic atmosphere. This property has 18 private offices, reception area, conference room, break room with kitchen, covered outside area, fenced in backyard lighted, fresh asphalt parking, This site is convenient to Easley, Greenville and Powdersville. Easy access with great visibility.

Date on Market:

2025-12-06

West Columbia Flex for Lease - Cayce/West Columbia

Located in the Overlook Business Center, 104 Vantage Point Drive offers a premier flex solution in West Columbia’s highly competitive industrial market. This property combines Class A office space with high-bay warehouse functionality, delivering an ideal environment for businesses seeking both professional presence and operational efficiency. The office component spans over 12,000 SF, featuring executive offices, conference rooms, and training areas, while the warehouse provides 18-foot clear height, one dock-high door, and one drive-in door for versatile loading options. The site includes a 3,000 SF fenced outdoor storage area and a 1,000 SF lean-to, complemented by 50 surface parking spaces for staff and visitors. Situated just one mile from Interstate 26 and two miles from Interstate 77, the property ensures seamless regional connectivity, while Columbia Metropolitan Airport is only 6.5 miles away for convenient air freight access. Surrounded by major distribution hubs, including Amazon, Husqvarna, and Lowe’s, this location positions tenants at the center of a thriving logistics network.

Date on Market:

2025-12-02