29 Serviced Offices for Lease in South Carolina, USA

Spartanburg Office for Lease - North Side/Rt 9 Corridor

Enter the innovation-driven economic landscape of Spartanburg, South Carolina, by leasing one of Corporate Center’s multifaceted spaces designed for office users, distributors, medical lab users, advanced manufacturing, R&D, and more. 111 Corporate Drive is a 48,300-square-foot industrial flex building located within Corporate Center, a premier business park in Spartanburg, South Carolina. Strategically positioned on 193 acres directly off Interstate 85, this Class A industrial property offers exceptional access to the Interstate 85 business corridor, connecting major Southeastern markets such as Charlotte, North Carolina, and Atlanta, Georgia. Corporate Center currently features 400,000 square feet of flexible office, warehouse, and manufacturing space, with plans to expand to 1.5 million square feet to accommodate immediate and long-term tenant growth. A 10,000-square-foot turnkey suite is currently available and has a full build-out ideal for office, lab, R&D, or light industrial use due to its high-spec infrastructure. It offers four external loading docks and two drive-in bays, wide column spacing, exterior walls with a high insulation rating, and high ceilings to create a mezzanine. The offices are fully furnished and ready for quick move-ins, plus an on-site generator ensures an uninterrupted power supply. Tenants benefit from being part of a synergistic business environment designed to support a wide range of commercial and industrial operations. The location offers significant logistical advantages, including proximity to the South Carolina Inland Port (SCIP), just 19 miles away, and Greenville-Spartanburg International Airport, located 21 miles from the site. SCIP alone handled nearly 2.8 million TEUs as of 2022, underscoring the region’s strength in freight and cargo movement. Corporate Center is also conveniently located near major employers such as Milliken (2.9 miles), Amazon Fulfillment (9.5 miles), and BMW Manufacturing (20 miles), making it an ideal location for companies seeking to integrate into a thriving industrial ecosystem. Spartanburg’s economy is powered by over 350 companies in the automotive, aerospace, biotech, energy, and advanced materials sectors, which together account for more than 30% of the local economic base. The area offers a robust and growing labor pool, with a population of 221,178 within a 10-mile radius and a projected annual growth rate of 2.7%, outpacing the national average. With its prime location, scalable infrastructure, and access to a skilled workforce, 111 Corporate Drive at Corporate Center presents a compelling opportunity for businesses seeking high-quality industrial space for lease in Spartanburg, South Carolina.

Property Type:

Flex

Date on Market:

2025-09-08

Greenville Office for Lease - Pelham Road

Located on the high-traffic Pelham Road corridor, the property provides excellent visibility, abundant parking, and easy access to I-385. Surrounded by major retail and restaurant amenities, it’s an ideal choice for businesses seeking accessibility, convenience, and a professional setting.

Date on Market:

2025-09-11

Rock Hill Office for Lease - York County

Date on Market:

2024-01-11

Hilton Head Office for Lease

This former doctor's office is positioned in the heart of Hilton Head’s Main Street business district. This professional office space offers an exceptional opportunity for companies seeking a prestigious address in one of South Carolina’s most desirable coastal communities. The property combines convenience, visibility, and a vibrant surrounding environment, making it ideal for firms that value accessibility and image.

Date on Market:

2025-11-14

Columbia Coworking for Lease - CBD

Columbia's vibrant business ecosystem, anchored by The Vista and Main Street, offers prime locations for serviced offices and coworking spaces. Proximity to the University of South Carolina ensures a steady talent pipeline, while major employers like Prisma Health and BlueCross BlueShield foster opportunities for growth in Columbia. The city's connectivity is enhanced by Columbia Metropolitan Airport.

Property Type:

Office

Date on Market:

2026-04-28

Daniel Island Coworking for Lease

Charleston’s thriving business ecosystem, anchored by Boeing and the Medical University of South Carolina, offers unparalleled commercial advantages. With easy access to Charleston International Airport and a robust talent pipeline from local universities, our serviced offices and coworking spaces in Charleston provide the perfect setting for growth in aerospace, healthcare, and technology sectors.

Property Type:

Office

Date on Market:

2026-04-13

Daniel Island Coworking for Lease

Work Steps from the Heart of Daniel Island Discover HQ Charleston at 115 Fairchild Street, a prime corporate building in one of Daniel Island’s most prestigious business areas. Positioned along Route 526 with excellent connectivity, this four-story center sits close to walking paths, parks, retail, restaurants, and the Tennis Center, combining professional convenience with lifestyle amenities. Designed to support business growth, this HQ location offers flexible office solutions for companies seeking a prominent presence in Charleston’s technology and corporate hub. With nearby amenities and easy access to the beltway, your team and clients can work, meet, and connect seamlessly.

Property Type:

Office

Date on Market:

2026-01-20

Greenville Coworking for Lease - Stone Ave/E North St Cor

Solidify Your Business’s Goals at 15-17 E Stone Avenue Open up to new opportunities with office space in Greenville, South Carolina. Located between major highways like Route 276 and Interstate 385, the city offers an ideal location for your business amidst South Carolina’s diverse industries. Welcome clients from Greenville Downtown Airport, just 3.5 miles away, and treat them to a variety of cuisines along W Stone Ave. Start your day with a barista-style coffee from your office’s fully stocked kitchen, and at the end of the workweek, take the 4.5-mile drive to Greenville Country Club for a relaxing round of golf. 15-17 E Stone Avenue offers a variety of options for every workday. Start in the open-plan workspaces, perfect for brainstorming sessions with your colleagues, and before lunch, move to the breakout spaces for a quieter focus. The bookable private suites are ideal for meetings and client presentations, and don’t worry about cleaning – the onsite support team is there to maintain the space. Your new workspace is equipped with ergonomic furniture for comfortable working, and the state-of-the-art video conferencing technology ensures you can keep in touch with international contacts without leaving your desk. As your business grows, adapt your flexible office space to fit your brand’s style and needs.

Property Type:

Office

Date on Market:

2025-08-21

Summerville Coworking for Lease - Outlying Berkeley County

Summerville's bustling commercial hubs like Nexton and Downtown Summerville provide prime locations for businesses to thrive. With excellent connectivity to Charleston International Airport and major highways, manufacturing giants like Bosch benefit from efficient supply chains. Our serviced offices and coworking spaces in Summerville offer seamless access to talent and industry connections.

Property Type:

Office

Date on Market:

2025-07-14

Columbia Coworking for Lease - CBD

Columbia's vibrant business ecosystem, anchored by The Vista and Main Street, offers prime locations for serviced offices and coworking spaces. Proximity to the University of South Carolina ensures a steady talent pipeline, while major employers like Prisma Health and BlueCross BlueShield foster opportunities for growth in Columbia. The city's connectivity is enhanced by Columbia Metropolitan Airport.

Property Type:

Office

Date on Market:

2025-07-10

North Charleston Coworking for Lease

5935 Rivers Avenue in North Charleston offers prime commercial relevance with close proximity to major transport routes, ensuring seamless access for clients and decision-makers. The location is well-connected, with Trident Medical Center and Bank of America Financial Center within walking distance, enhancing professional credibility and operational convenience. Businesses can benefit from the diverse talent pool and networking opportunities in the area. Flexible workspace options, including offices and coworking, provide cost-effective solutions for dynamic business needs. This strategic location supports efficient operations and fosters growth, making it an ideal choice for establishing a local business presence.

Property Type:

Flex

Date on Market:

2025-07-09

Sumter Coworking for Lease

Start strong with office space at West Hampton Avenue, Sumter Secure a flexible office space in the welcoming community of Sumter, South Carolina. Placed in the heart of the city, 208 West Hampton Avenue offers a place within Sumter’s diverse economy with industries such as healthcare, retail, manufacturing and many more. Make use of Sumter’s well-connected local roads and highways 521 and 15 for travelling further afield. For your international clients, Columbia Metropolitan Airport is approximately 81km away. Use your lunch break for a leisurely stroll in Swan Lake Iris Gardens only 2.5km from your office space. The local restaurants and shops on West Liberty Street, 1.6km away, make the perfect choice for some after-work food or activities. With a convenient location that provides easy access to key areas of the city, your new fully furnished office space comes with onsite parking spaces and business-grade WiFi for uninterrupted workflows. Catch up with colleagues over a hot drink in the fully stocked kitchens and create a working environment alive with ideas in the open-plan offices. If you’re in need of some privacy, book an office or use the large conference rooms for interviews and meetings. Present with confidence on the video conferencing technology and widescreen TVs. Whilst you focus on growing your business, the dedicated support team will take care of the utilities, security and cleaning.

Property Type:

Office

Date on Market:

2025-05-29

Fort Mill Office/Medical for Lease - York County

Property Type:

Office

Date on Market:

2025-04-23

Greenville Coworking for Lease - Greenville CBD

Stand out from the crowd at Spaces Falls Tower, the new landmark for business and leisure in Greenville. An all-glass building flooded with natural light in a highly-desirable Downtown Greenville location – if you’re looking for one of the best workspaces in South Carolina, you’ve just found it. Spaces Falls Tower is in a prestigious new 17-story development on tree-lined Main Street, offering productive, designer workspaces surrounded by amenities and attractions. You’ll find the flexible and inspiring spaces your business needs, whether you’re looking to rent private or shared offices or to hire a meeting room in Greenville. Plug into our super-fast, business-quality Wi-Fi and make connections with our dynamic community of entrepreneurs. Chat with our friendly, professional staff, who offer admin support to help your day go more smoothly so you can focus on growing your business. At Spaces Falls Tower, you’re steps away from a vibrant plaza with shops and eateries. Venture a little further where Downtown Greenville has developed into a prominent dining and entertainment destination, with more than 90 restaurants and bars along Main Street. Take a head-clearing stroll to the riverside and Falls Park on the Reedy. And to ignite your creativity, you’re also close to cultural museums and art galleries, year-round festivals and live music and performances across the road at the Peace Center. Find inspiring workspaces at Spaces Falls Tower: • Dream Office: Enjoy the perks of a private office with customizable workspaces for any team, flexible contracts that flow with your business, and 24/7 access so you can work on your time. • Join the Club: Unlock thousands of coworking spaces throughout the globe and tap into creative environments with a thriving business community of like-minded professionals. • Lock-In: Get the best of both worlds with the perks of a coworking membership and the privacy of your own office, including 24/7 access, a personal locker, and reservable meeting spaces. • Collaborate: Book one of the countless meeting rooms, open to members and non-members, designed to keep your team or clients comfortable, creative, and focused. • Virtual Office: Get a prestigious professional address with mail handling, phone answering services, access to networking events, and access to Spaces’ global network of business lounges. Just so you know; all images shown in this listing are from Spaces locations, but they may not correspond to this specific one.

Property Type:

Office

Date on Market:

2025-03-31

Hilton Head Island Coworking for Lease

Get ahead in business at Hilton Head Island, South Carolina Ensure your business ambitions are heading in the right direction with modern office space at Hilton Head Island, South Carolina. Travel easily to the Courtyard Building situated on the crossroads of key main roads that cut across the island. Looking to attract more guests from overseas? Greet them at Island Head Ferry Terminal or Hilton Head Island Airport, approximately a 9.5-mile or 12-mile drive away, respectively. Whether you’re planning quick meetings or long-term projects, we have the perfect space for you. Get all the business support you need to succeed at Hilton Head Island, South Carolina. Whether you’re collaborating in our fully furnished coworking areas, pitching in our quiet meeting rooms, or working solo in our private spaces, our professional offices give you the perfect platform to thrive. A warm welcome awaits from our friendly reception team, as does hot barista-style coffee from the kitchen. Jump online anytime with business-grade Wi-Fi. When it’s time to switch off, make the most of 19 miles of beachfront, three local parks, and a museum. Plus, swing by one of the many golf courses with colleagues. Find a place to thrive at Regus 32 Office Park Road: • Professional Offices: Elegant office space equipped with modern furniture and amenities, easily scalable for individual professionals or entire teams. Move into a turnkey office, pay by day, or custom tailor a unique suite to accelerate organizational success. • Community: Work wherever you need to be and discover a dynamic mix of businesses and like-minded individuals. Regular networking and personal growth events and sociable workspaces foster collaboration and open new opportunities for your business. • Virtual Workspace: Build your presence anywhere in the world with a new virtual address. Whether simply to forward mail, hold a meeting, or even answer calls, Regus’ virtual offices have the services you need. • Collaboration: Host a meeting in every major city in the world and impress local clients with industry-leading technologies in one of the fully serviced meeting spaces. There is a room for every need with day-of booking for anything from private conference rooms to inspiring training spaces. • Join the Club: Regus’ thriving global network of beautifully designed offices provides the flexibility to work anywhere and everywhere. Reserve space on the move via the Regus app and get to work from any of the business lounges, dedicated desks, or your own private office.

Property Type:

Office

Date on Market:

2024-08-06

North Myrtle Beach Coworking for Lease

Make Waves in Your Business at 2nd Avenue Set sail for business success with fully serviced office space at 2nd Avenue, located in the heart of North Myrtle Beach. Achieve the ideal work-life balance by securing flexible office space complete with coworking spaces, high-tech conferencing rooms, and breakout areas. Seize valuable opportunities to collaborate with local entrepreneurs, using the Grand Strand Medical Center Bus Stop to travel between meetings. Cast your net further afield and create partnerships overseas as Myrtle Beach International Airport sits only 26 miles away. Whether you need a quiet space to plug in or a permanent base for your business, you’ll find what you need here. Find inspiration in the breathtaking views of North Myrtle Beach’s coastline. Our dynamic office space is bathed in an abundance of natural light brought in through expansive windows. Count on our dependable and high-speed WiFi ensuring you boost productivity and meet critical deadlines. Leave the cleaning, security, and utilities to our friendly support team, allowing you to shift your focus entirely to your business objectives. Unwind after a long day by taking a leisurely stroll along the beach, immersing yourself in the local culture at nearby art galleries and theaters, or relishing in the southern hospitality at one of many nearby restaurants.

Property Type:

Office

Date on Market:

2023-08-29

Fort Mill Office, Office/Retail for Lease - York County

100 Stone Village Drive consists of TD Bank and several medical and professional office tenants.

Date on Market:

2025-04-07

Columbia Coworking for Lease - St Andrews

Carve a new path at Regus 140 Stoneridge Drive. Find a new way of working with ready-to-use, scalable workspace in Columbia. Base your business between the banks of the Broad and Saluda with premium workspace in northwest Columbia. Get the best of both worlds here, immersing yourself in a dynamic commercial scene that’s surrounded by greenery and nature. Scale your set-up easily to suit your business’s needs with our flexible plans. Make the most of the on-site deli to keep you energized, and when you need to take a break or think through your ideas, just step outside into the grounds. Find a place to thrive at Regus 140 Stoneridge Drive: • Professional Offices: Elegant office space with modern furniture and amenities, easily scalable for individual professionals or entire teams. Move into a turnkey office, pay by the day, or custom tailor a unique suite to accelerate organizational success. • Community: Work wherever you need to be and discover a dynamic mix of businesses and like-minded individuals. Regular networking, personal growth events, and sociable workspaces foster collaboration and open new opportunities for your business. • Virtual Workspace: Build your presence anywhere in the world with a new virtual address. Whether simply to forward mail, hold a meeting, or even answer calls, Regus’ virtual offices have the services you need. • Collaboration: Host a meeting in every major city in the world and impress local clients with industry-leading technologies in one of the fully serviced meeting spaces. There is a room for every need with day-of booking, from private conference rooms to inspiring training spaces. • Join the Club: Regus’ thriving global network of beautifully designed offices provides the flexibility to work anywhere and everywhere. Reserve space on the move via the Regus app and get to work from any of the business lounges, dedicated desks, or your own private office. All images shown in this listing belong to Regus locations but may not correspond to this specific center.

Property Type:

Office

Date on Market:

2025-03-27

Aiken Coworking for Lease - Outlying Aiken County

Boost Your Productivity in a Calming, Leafy Location Receive a warm welcome when you build your business in charming South Carolina. South Aiken is in a convenient and pleasant location, close to Interstate 20 and with ample parking. Stay focused in this peaceful green environment, surrounded by parks and nature reserves. Do your best work on the first floor of the modern building, where the light floods in through the expansive windows. And all your amenities are just a short drive away.

Property Type:

Office

Date on Market:

2022-10-27

Charleston Office for Lease - Daniel Island

RARE, WATERFRONT EXECUTIVE OFFICE SPACES --DANIEL ISLAND at CLEMENTS FERRY. PLEASE NOTE: Space is subdivided into executive suites and conference areas -- the listed 4,800 square footage is for the full footprint. Offices range between 130 and 220 square feet and cost is all inclusive, providing immediate move in and ability for user's business to be fully operational same day. This space is perfect for Charleston locals or visitors in need of a space while in town. Daily executive conference room rental options also available. Marina Suites redefines the executive office experience, combining luxury with functionality right on the waterfront of Clouter Creek. Each office is designed to foster creativity and productivity. Enjoy amenities like high-speed private Wi-Fi, 24/7 secured access, furnished suites, and a kitchen & coffee bar. Relax or meet on our outdoor waterfront porch & patio, all designed to enhance your productivity and peace. Marina Suites is a property unlike anything on the market. We value waterfront views over white noise and strive to keep the user process simple. Executive conference facilities, breakout meeting space and outdoor entertaining venues are included in monthly rates. Offices come furnished with sit to stand desks, collaboration tables and storage options, or the ability to furnish with your favorite pieces. Marina Suites removes the hassle of start-up costs and long-term service contracts, providing an all-inclusive, move in ready space for terms from 1 month to 1 year. As a flexible, cost effective workspace solution we are ideal for remote employees, new market entries, mobile workforces, satellite offices and as a broker resource while settling or constructing permanent office space. You work hard to provide the luxuries of island life, why not enjoy it in the process? Pay only for what you need and focus on the success of your business…and maybe the tide chart. Schedule a Tour Today! info@32south.com 843-97-SUITE (78483) www.marinasuitesdi.com

Date on Market:

2026-04-13

Greenville Office for Lease - West End

High ceilings and plenty of natural light offered in an excellent location near the Westend. Roof-top access with grill and tables acts as an additional fair weather conference room. 28 closed-door offices and 6 workstation cubes remaining for lease. WiFi and utilities are included. Free parking and secure coded building access 24/7. Private on-site parking is included along with utilities

Date on Market:

2020-01-28

Greenville Coworking for Lease - West End

Venture X Plush Mills is the solution for all sizes of long-term, short-term, or quick occupancy requirements. Plush Mills can accommodate up to 50 employees with private offices, team rooms, and private suites. With their roots in hospitality, Venture X provides companies with move-in-ready, all-inclusive office space, allowing each business to focus on its tasks while being part of a larger community of professionals. Venture X meets security and compliance standards for HIPAA, Sarbanes-Oxley, PCI-DSS, and GLBA. Move your company into 141 Traction Street with Venture X and receive access to excellent on-site amenities, including 24/7 access and keyed entry, secure high-speed internet, security monitoring, and secure cloud-based infrastructure. Janitorial services and office utilities are included with the property. Tenants can access meeting rooms, lounges, and fully furnished office spaces with guest reception and concierge services. Complimentary refreshments and premium snacks are available, and on-site parking is free. Located in the heart of Greenville, 141 Traction Street allows convenient access to Highway 123 and Interstate 185. Greenville is a fast-growing, vibrant city noted for its strong job market, numerous universities, and gorgeous scenery. With tall trees forming a canopy of leaves above the streets, wide sidewalks, beautiful flowerbeds, and historic architecture, Downtown Greenville is an attractive destination to live, work, and play. Venture X is an ideal choice for your coworking needs.

Property Type:

Office

Date on Market:

2026-03-05

North Charleston Coworking for Lease

Airport location in a dynamic commercial district. Locate your office amongst the businesses flocking to the fast-growing commercial district near Charleston International Airport. Sitting in the four-acre Executive Park, the Faber Center is a top-tier building and a prime destination. The inspiring contemporary design of this Class A building welcomes you with an impressive granite and marble lobby and features a relaxing lounge area. Ideal for clients flying into Charleston, the area offers a great choice of hotels and restaurants. Find a place to thrive at Regus Faber Center: • Professional Offices: Elegant office space equipped with modern furniture and amenities, easily scalable for individual professionals or entire teams. Move into a turnkey office, pay by day, or custom tailor a unique suite to accelerate organizational success. • Community: Work wherever you need to be and discover a dynamic mix of businesses and like-minded individuals. Regular networking and personal growth events and sociable workspaces foster collaboration and open new opportunities for your business. • Virtual Workspace: Build your presence anywhere in the world with a new virtual address. Whether simply to forward mail, hold a meeting, or even answer calls, Regus’ virtual offices have the services you need. • Collaboration: Host a meeting in every major city in the world and impress local clients with industry-leading technologies in one of the fully serviced meeting spaces. There is a room for every need with day-of booking for anything from private conference rooms to inspiring training spaces. • Join the Club: Regus’ thriving global network of beautifully designed offices provides the flexibility to work anywhere and everywhere. Reserve space on the move via the Regus app and get to work from any of the business lounges, dedicated desks, or your own private office. All images shown in this listing belong to Regus’ locations but may not correspond to this specific center.

Property Type:

Office

Date on Market:

2025-03-28

Greenville Coworking for Lease - Woodruff/I-385 Corridor

Property Type:

Office

Date on Market:

2013-04-03