27 Storefront Properties for Lease in Fort Myers, FL, USA

Fort Myers Retail for Lease - S Ft Myers/San Carlos

LSI Companies presents Alico Business Center, Unit 150. This 3,300 sq. ft. retail / office suite offers a spacious open area that can accommodate a variety of layouts. With multiple restrooms, washer & dryer hook ups with 3-phase power, LED lighting throughout, and plenty of parking, this space is ideal for a medical user, large showroom, or a variety of other uses. LOCATION HIGHLIGHTS: • 0.2± miles to I-75 • 1± miles to Gulf Coast Town Center • 2.5± miles to Amazon Distribution Center • 4.2± miles to Florida Gulf Coast University (FGCU) • 4.7± miles to Hertz Arena • 5± miles to SWFL International Airport (RSW) • 15± miles to Downtown Fort Myers • 16± miles to North Naples

Date on Market:

2026-05-01

Fort Myers Medical for Lease - S Ft Myers/San Carlos

Property Type:

Retail

Date on Market:

2026-04-15

Fort Myers Retail for Lease - S Ft Myers/San Carlos

Invest Florida, is proud to represent this prime US-41 retail space located 1/4 mile from College Parkway (busiest intersection in Lee County). This highly visible shopping center with pylon signage on US-41 is in the heart of Fort Myers shopping district with close proximity to Bell Tower Shops is the perfect location for your business! The space is currently 2,815 SQFT. and has the ability to be subdivided into. two 1,400 +/- SQFT spaces. The space has extra plumbing to accommodate a full service beauty salon for both hair and nails. Also this space is perfect for many other uses such as retail, clothing store, thrift store, medical office, nail salon, hair salon, barber shop, fast casual dining, showroom, animal hospital, groomer, gym, pilates studio and many other uses. This end-cap space currently has an open floor plan with two ADA bathrooms located in rear of space. This space is ready for you to put your own touches in space making it your next location! Please schedule a showing today and see the possibilities with lease incentives available for longer-term leases and qualified tenant.

Date on Market:

2026-04-13

Fort Myers Retail for Lease - City of Ft Myers

Date on Market:

2026-03-30

Fort Myers Office for Lease - S Ft Myers/San Carlos

HIGH-TRAFFIC SAN CARLOS BLVD LOCATION – MAKE YOUR BUSINESS IMPOSSIBLE TO MISS 15661 San Carlos Blvd | Fort Myers, FL If visibility matters to your business, this is where you need to be. Located directly on San Carlos Boulevard — one of Fort Myers’ busiest commercial corridors — this property delivers nonstop daily traffic, strong local demographics, and direct access to Fort Myers Beach. Your signage is seen. Your storefront gets noticed. Your business grows. This is a rare opportunity to secure space in a high-demand trade area surrounded by dense residential communities, hospitality, and established retail. Why This Location Wins: Prime frontage on San Carlos Blvd High daily traffic counts Excellent signage exposure Easy access & ample parking Minutes to Fort Myers Beach Strong year-round and seasonal customer base Ideal for: Medical & wellness concepts Boutique retail Professional office Fitness, beauty, or specialty services Destination businesses seeking exposure San Carlos Blvd continues to experience strong redevelopment and growth — space along this corridor does not stay available long.

Date on Market:

2026-02-23

Fort Myers Retail for Lease - City of Ft Myers

LSI Companies is pleased to present a pre-leasing opportunity at Eastwood Commons, a 13,500± Sq. Ft. retail neighborhood center development in Fort Myers, FL. Located between Colonial Boulevard and State Road-82, near I-75, the property offers high-traffic exposure and access to major retailers like Publix, Walmart, and BJ’s Wholesale Club. With an adjacent 325± unit apartment complex, a 110-Suite Hilton Hotel, and two 1–2± acre outparcels, this will further drive the properties demand and the areas growth. LEASE RATES: In Line: $42.00 PSF NNN End Cap: $46.00 PSF NN PROPERTY HIGHLIGHTS: • 1,350–2,700 Sq. Ft Units • CG zoning permits a wide variety of commercial and residential uses • With 480± linear feet of frontage on Ortiz Avenue within the City of Fort Myers • Direct access to Hanson Street (AADT 20,600±) & Ortiz Avenue (AADT 20,600±) • Less than 1.2 miles from I-75 with options for Exit 138 or 136 and within close proximity to State Road-82 and Colonial Boulevard • Median Household Income $61,764 (2 mi) • Situated in a high growth corridor and surrounded by amenities, attractions, and outdoor recreational activities

Date on Market:

2025-05-05

Fort Myers Retail for Lease - S Ft Myers/San Carlos

Date on Market:

2026-03-15

Fort Myers Flex for Lease - S Ft Myers/San Carlos

Date on Market:

2026-01-21

Fort Myers Office, Office/Retail for Lease - S Ft Myers/San Carlos

In line space in a 10,000 sf in a neighborhood retail strip plaza. High visibility location with excellent building and pylon sign opportunities. Area of dense retail concentration in desirable South Ft. Myers. Ample parking.

Date on Market:

2026-04-10

Fort Myers Office/Retail for Lease - S Ft Myers/San Carlos

3 MONTHS FREE! The newly managed building has undergone a stunning transformation and is ready for occupancy! At major traffic light/ intersection of Tamiami Trail. Only 1 unit available! Has tall ceilings, beautifully redone floor plan and space. 2 private offices plus reception and bathroom. All freshly remodeled. Plenty of parking available. Large signage included directly on Tamiami Trl.

Property Type:

Retail

Date on Market:

2025-10-24

Fort Myers Office/Medical for Lease - S Ft Myers/San Carlos

Preserve Plaza is a mix of current medical and professional offices.

Property Type:

Retail

Date on Market:

2025-11-11

Fort Myers Office, Office/Medical for Lease - S Ft Myers/San Carlos

Discover the perfect location for your business at The Plaza at Gladiolus Preserve. Available units are ideally suited for a professional office users, personal trainer, boutique fitness center, or wellness studio. With a fantastic tenant mix already in place, you’ll benefit from the synergy of neighboring businesses and a well-trafficked location. The space is designed to accommodate a variety of uses and offers the flexibility to make it your own.

Date on Market:

2026-02-11

Fort Myers Office for Lease - S Ft Myers/San Carlos

Bella Villa Shops is a boutique shopping/office center in the fastest growing area in Fort Myers, FL. This two-story Mediterranean building has a nice mix of retail and office tenants offering amenities like hair and nails, spa, restaurant and small boutique retail and office tenants. The building offers two large second floor terraces for hosting events and has beautiful exterior accents. The building sits directly facing Daniels Parkway and is centrally located with close access to I-75, SWFL international airport, Gulf Coast Medical Center and within 10 minutes of US-41. The area directly around Bella Villa shops consists of Publix Grocery, Starbucks, Dunkin Doughnuts, Dry Cleaners, Bagel Shop, restaurants and many more places in close proximity to walk.

Property Type:

Retail

Date on Market:

2026-03-16

Fort Myers Retail for Lease - City of Ft Myers

The Forum at Fort Myers is a 700-acre Destination Development consisting of retail, office, medical, single-family, multi-family, hospitality, entertainment users and much more. Forum Centre is located at 3398 Forum Boulevard, Fort Myers, Florida and is located at the main (South) entrance to the Forum just off I-75 (Exit 136) on Colonial Boulevard. Neighboring tenants include Target, Home Depot (#1 HD in the country), Firehouse Subs, Great Clips, GNC, Staples, Ross, Starbucks, Holiday Inn Express and much more.

Date on Market:

2023-11-07

Fort Myers Coworking for Lease - S Ft Myers/San Carlos

We Create Thoughtful, Work Friendly Space. Creative Executive Space was creatively designed with you in mind! Ideal for small business owners and companies who seek a dynamic and professional work environment. Beautifully appointed to suit even the most discriminating clientele. We feature prime office frontage on US-41 (Tamiami Trail) conveniently located at a traffic light for easy ingress and egress. Located 1.5 miles south of Alico Road / Metro Extended and 7 miles to I-75 via Alico Road. Nearby you will find Gulf Coast Town Center, Coconut Point, Florida Gulf Coast University and Hertz's Global Headquarters. The Plaza is undergoing a complete facelift with new paint, awnings and landscaping. State-of-the-Art high-speed fiber optic internet, featuring secure VLAN and WiFi for each tenant. Our network is customized to meet and prioritize specific VoIP, internet and bandwidth usage requirements. Static IP Addresses available upon request. Superior upload / download speeds! Upscale offices provide our clients with a private, secure space featuring 24/7 access. Perfect for business professionals who have outgrown their home office, have started a new business or are adjusting to current office space requirements. Providing the space you need to run your business in an efficient, cost-effective and competitive manner is our main priority. Our economies of scale allow us to deliver an image of success at a fraction of the traditional cost. Our Executive Offices provide your business with the ideal mix of infrastructure and technology support in a work environment created to perform. Our Growth Flexibility program provides our tenants the flexibility of adjusting (up-size/down-size) their work space to suit their needs. Franchisees will find that our infrastructure will accommodate Franchisee systems; including VoIP phones, firewalls and other proprietary equipment. If you've ever gone looking for office space, you know the costs add up pretty quickly. Take a look at what it would ordinarily cost you to open a full-service office with the amenities available at Creative Executive Space.

Property Type:

Retail

Date on Market:

2026-04-03

Fort Myers Retail for Lease - S Ft Myers/San Carlos

HIGHLY VISIBLE RETAIL/OFFICE/MEDICAL CENTER; DIRECTLY LOCATED AT SIGNALIZED INTERSECTION OF SR 739 (MICHAEL G. RIPPE PARKWAY) AND U.S. 41 WITH INGRESS & EGRESS; 55,000 AVERAGE DAILY TRAFFIC VOLUME; SW Fla Int’l Airport…...16mins. Fla. Gulf Coast Univ….17mins. Gulf Coast Town Ctr….12mins. Bell Tower Shops……..12mins. Coconut Pt. Mall………13mins. Hertz Corp HQ…………09mins

Date on Market:

2026-03-13

Fort Myers Land for Lease - S Ft Myers/San Carlos

EXECUTIVE SUMMARY: LSI Companies is pleased to present a 1.51± acre ground lease or build-to-suit opportunity in the rapidly expanding Daniels Parkway corridor in Fort Myers, Florida. The site offers direct frontage and visibility along one of the region’s highest trafficked arterial corridors and is positioned within a high-growth residential and workforce trade area. Developer owned property offered for a long-term ground lease basis or a customized build-to-suit solution tailored to tenant specifications. Building size, parking configuration, and drive-thru layout may be accommodated subject to municipal approval. Flexible lease structures available for credit tenants seeking high-visibility positions along Daniels Parkway. Adjacent to Alessio Air Commerce Park, a mixed-planned development set to deliver 115,000+ Sq. Ft. of industrial/commercial space in 2027. *CALL FOR GROUND LEASE RATES & BUILD-TO-SUIT PRICING PROPERTY HIGHLIGHTS: • 1.51± Acres • Ground Lease or Build-to-Suit • Conceptual site plan flexibility (drive-thru capable) • Direct frontage on Daniels Parkway (54,500 AADT) • Utilities available to site • Zoned Mixed Planned Development (MPD) allowing for a multitude of uses • Strong day-time population driven by nearby employment hubs • Limited remaining commercial pad opportunities along Daniels Parkway • Underserved retail pocket relative to surrounding density • Strong demographics within immediate trade area • Ideal for coffee shops, medical, or auto service users

Property Subtype:

Commercial

Date on Market:

2026-04-10

Fort Myers Retail for Lease - S Ft Myers/San Carlos

A 4,299 SF second-generation restaurant space located in Fort Myers, Florida is available for lease. It is currently an operating restaurant, so please do not disturb the tenant. This well-built-out restaurant offers a rare opportunity for an operator to step into a turnkey space with significant infrastructure already in place. It is a fully built-out restaurant with existing hood, kitchen infrastructure, and dining layout. All furniture, fixtures, and equipment (FF&E) are available for purchase, allowing for a streamlined transition and substantial savings compared to new construction. Great fit for a myriad concepts. Full liquor license and outdoor seating. Traffic light approved for Daniels and Apaloosa Lane will be a game changer for this location. Great exposure on Daniels and large lake in front being built which will enhance the appeal and foot traffic.

Date on Market:

2026-04-05

Fort Myers Retail for Lease - S Ft Myers/San Carlos

For Lease. Bottom is 2700 sq feet - restaurant / retail Upstairs is 2700 sq feet - 3 units for AIRBNB

Date on Market:

2026-02-10

Fort Myers Office/Medical for Lease - S Ft Myers/San Carlos

Position your practice in one of Fort Myers’ most vibrant corridors with this prime medical/dental sublease opportunity at 11551 Majestic Palms Blvd. This 4,000 SF space offers exceptional visibility and convenient access from major thoroughfares, including San Carlos Boulevard and Majestic Palms Boulevard. Located in a rapidly growing area surrounded by new residential communities, the property benefits from strong demographics, with over 100,000 residents and an average household income exceeding $111,000 within a five-mile radius. The site is strategically positioned near leading retailers such as Target, Publix, Planet Fitness, Walgreens, and McDonald’s, creating a steady flow of consumer traffic and reinforcing its appeal for healthcare providers seeking high exposure. Ample parking ensures ease of access for patients, while the modern layout supports a variety of medical or dental configurations. This sublease offers flexibility and an opportunity to establish or expand your practice in a thriving market known for its robust population growth and affluent households. Fort Myers continues to attract professionals and retirees alike, offering a dynamic mix of residential and commercial development. The property’s proximity to major roads and community amenities enhances connectivity and convenience, making it an ideal choice for practitioners focused on accessibility and patient experience. Secure your position in this sought-after location and leverage the advantages of a well-established commercial hub.

Property Type:

Retail

Date on Market:

2025-12-10

Fort Myers Land for Lease - S Ft Myers/San Carlos

Ready-to-build outparcels available for ground lease. 0.54 acres to 2.22 acres available. Vintage Commerce Center is located at the NWQ of I-75 and Alico Road. Tenant's include Floor & Decor, McDonald's, Marriott Towne Place & Suites, HCA Medical, Roadies, and Centro Apartments. Excellent demographics, high traffic counts, infrastructure/roads/utilities in place. Zoned for a wide variety of uses: retail, restaurant with or without drive-thru, gas station, bank, office, and medical.

Property Subtype:

Commercial

Date on Market:

2025-09-04

Fort Myers Land for Lease - City of Ft Myers

Located at the SW Quadrant of SR-82 and Forum Blvd, this ±1.51-acre pad site offers a rare opportunity in the rapidly expanding Forum corridor of Fort Myers. Located amidst thousands of new residential units, including Asher Park, The Mark at Colonial, and Sherwood Emblem, this site benefits from exceptional visibility with over 42,000 vehicles per day and easy access to I-75. Build-to-suit options from 2,500 to 10,000 SF are available, ideal for retail, medical, or service uses. Surrounded by high-growth residential and commercial developments, and with limited remaining pads in the area, this site presents a unique opportunity to join one of Fort Myers’ fastest-growing mixed-use communities.

Property Subtype:

Commercial

Date on Market:

2025-08-07

Lehigh Acres Office/Retail for Lease - City of Ft Myers

Property Type:

Retail

Date on Market:

2025-02-26

Fort Myers Office/Retail, Retail for Lease - S Ft Myers/San Carlos

San Carlos Plaza – Retail and Service Center Along the U.S. 41 Corridor San Carlos Plaza is a 76,500 SF Re-Developed Neighborhood Shopping Center located in a prime high growth area of South Lee County between Fort Myers and Estero/Bonita Springs. San Carlos Plaza is strategically positioned at the lighted intersection of US 41 and Sanibel Blvd. with over 900 SF of frontage and an ADT of over 44,500 vehicles. (US 41 is the primary commercial corridor linking Fort Myers to Estero, Bonita Springs and Naples and Sanibel Blvd. is a major access to the residential areas of San Carlos Park.) San Carlos Plaza anchors include: Sunshine Ace Hardware, Planet Fitness, AUTOZONE, Dollar General, and WINGSTOP. The balance of the other shops includes a variety of restaurants, retail and service tenants catering to the needs of the surrounding communities.

Date on Market:

2025-11-18