141 Storefront Properties for Lease in San Francisco, CA, USA

San Francisco Office, Office/Retail for Lease - West of Van Ness

At the corner of Union and Buchanan, find 2001 Union Street, a trophy office building in San Francisco, California. This marvelous property spans over 84,236 square feet with six stories of office, retail, medical, and underground parking. The building was renovated in 2017, and each unit has refined modern features, including glassed rooms, updated flooring, exposed ceilings, and floor-to-ceiling windows with views of the Bay. Amenities at 2001 Union Street include an on-site property manager, underground fee parking, bike storage, air conditioning, and ground-floor storefront retail and dining. 2001 Union Street offers exceptional accessibility to the Golden Gate Bridge and the San Francisco Bay via Highway 101. Getting around town from the office without a car is easy as several bus lines stop nearby. This landmark building is in the heart of one of San Francisco's most well-known neighborhoods, Cow Hollow. Cow Hollow is a desirable area that showcases Victorian and Edwardian-style homes, world-class boutique shopping, and ample entertainment opportunities. This upscale residential neighborhood draws in a diverse mix of young professionals and delivers the perfect walkable urban location with something to do on every corner.

Date on Market:

2026-08-11

San Francisco Office/Medical, Office/Retail for Lease - West of Van Ness

Date on Market:

2026-08-27

San Francisco Retail for Lease - Southern City

Date on Market:

2026-08-25

San Francisco Office for Lease - Southern City

Property Type:

Retail

Date on Market:

2026-08-20

San Francisco Flex for Lease - Mission/Potrero

150 Valencia Street offers a rare ±16,500 SF full-building opportunity near Cerebral Valley. The property features two open floors, second-floor drive-in access, high ceilings, a ±3,170 SF parking lot, outdoor space, and high-visibility corner frontage. Perfect for a Company that needs drive in Access and high ceilings.

Property Type:

Retail

Date on Market:

2026-08-14

San Francisco Retail for Lease - West of Van Ness

Date on Market:

2026-07-27

San Francisco Office for Lease - South of Market

Property Type:

Retail

Date on Market:

2026-07-27

San Francisco Office for Lease - West of Van Ness

Property Type:

Retail

Date on Market:

2026-07-20

San Francisco Retail for Lease - Mission/Potrero

302 Valencia is currently occupied by Aurora Studio Deli. The approximately 2,000 square feet include a mezzanine of about 300 square feet in excellent conditions. There is no kitchen hood but Aurora Studio bakes with a Combi SOTA oven. The current owner is asking $98,000 for the assets of the business, including kitchen equipment and refrigerators, furniture, liquor 41 and entertainment licenses and wine inventory valued at approximately $30,000. Current monthly rent is $4,750 and increases to $4,940 on October 1, 2026. There are three more years on the current lease with a five-year option. Assignment of lease and assets sale is subject to landlord approval.

Property Type:

Multifamily

Date on Market:

2026-07-17

San Francisco Office/Medical for Lease - West of Van Ness

Property Type:

Retail

Date on Market:

2026-07-21

San Francisco Flex for Lease - Mission/Potrero

Property Type:

Retail

Date on Market:

2026-07-14

San Francisco Retail for Lease - West of Van Ness

Desirable Haight-Ashbury location, walkable to nearby amenities and to surrounding neighborhoods.

Property Type:

Multifamily

Date on Market:

2026-07-01

San Francisco Industrial for Lease - Southern City

Property Type:

Retail

Date on Market:

2026-06-29

San Francisco Retail for Lease - Southern City

Prime Castro Retail Space Available – Ideal for Nursery & Florist or General Retail Use Location: 566 Castro Street, San Francisco, CA Bring your green thumb to one of San Francisco’s most vibrant and high-foot-traffic neighborhoods! Previously home to the beloved "Hortica" nursery, this well-known retail space is now available for lease. We are specifically seeking a passionate tenant looking to open a nursery, garden center, or florist shop to continue a blooming tradition at this location. Key Features: Proven Location: Highly visible storefront in the heart of the historic Castro District. Established Community Roots: Neighbors and locals already associate this specific address with plants, gardening, and floral arrangements. Flexible Layout: Perfect for displaying vibrant floral arrangements, unique houseplants, and gardening supplies, has a large backyard great for plants, flower displays, and merchandising. Turn your botanical business dreams into reality in a neighborhood that loves to support local commerce. Contact Information: For leasing inquiries, terms, or to schedule a viewing, please contact Riki Tang at (650)302-6795 or retailcre8tor@gmail.com

Date on Market:

2026-07-01

San Francisco Office/Retail for Lease - West of Van Ness

4200 17th Street presents a rare opportunity to establish a business in one of San Francisco's most vibrant and high-traffic commercial corridors. This well-configured commercial space offers flexibility for a wide range of retail, professional service, or office uses, with ground-floor visibility and upper-level private workspace, all within walking distance of the Castro's core amenities and transit connections.

Property Type:

Retail

Date on Market:

2026-06-25

San Francisco Office/Medical for Lease - Southern City

The property is located on Mission Street near the intersection of Geneva Avenue in San Francisco. It offers street-level retail or professional office space with built-out offices and plumbing infrastructure. The area is served by multiple MUNI lines and is within walking distance of a BART station. The location experiences significant foot and vehicle traffic along a major city corridor. Parking options are available on nearby streets.

Property Type:

Retail

Date on Market:

2026-06-23

San Francisco Retail for Lease - Mission/Potrero

Date on Market:

2026-06-16

San Francisco Retail for Lease - Southern City

FOR LEASE | 3417 Mission Street, San Francisco, CA Prime Mission District Retail / Showroom / Creative Commercial Space Approx. 1,190 Sq. Ft. Position your business in the heart of San Francisco's vibrant Mission District. This highly visible street-front commercial space offers an open and flexible floor plan ideal for retail, gallery, showroom, creative office, wellness, beauty, design studio, specialty services, and a variety of other commercial uses. Recently refreshed with modern finishes, the space features soaring ceilings, expansive storefront windows, abundant natural light, and excellent street presence along one of San Francisco's most active commercial corridors. Property Highlights Approximately 1,190 square feet Large open retail/showroom area Private office or storage room Private restroom High ceilings with exposed beams Abundant natural light Attractive polished flooring Excellent storefront visibility Strong pedestrian and vehicle traffic Flexible layout suitable for numerous business types Prominent Mission Street location Surrounded by restaurants, cafés, retailers, and neighborhood services Easy access to public transportation and major commuter routes Location Situated on bustling Mission Street between Bernal Heights and the Excelsior District, this location benefits from consistent neighborhood traffic and excellent accessibility. The surrounding area is home to a diverse mix of established local businesses, national retailers, dining destinations, and residential neighborhoods, creating a strong customer base for a variety of commercial uses. Ideal Uses Boutique Retail Specialty Retail Showroom Art Gallery Design Studio Creative Office Wellness Studio Beauty Services Professional Services Specialty Food (subject to approvals)

Date on Market:

2026-06-04

San Francisco Office for Lease - Southern City

Property Type:

Retail

Date on Market:

2026-05-11

San Francisco Industrial for Lease - Van Ness/Chinatown

Located in the heart of Nob Hill along a major corridor leading to Downtown San Francisco, 865 Post Street offers approximately 5,800 square feet of highly adaptable commercial space with an integrated residential/live-work component. This unique property is ideally suited for a wide range of users including creative office, showroom, boutique production, light industrial, or live-work operators seeking a central San Francisco location. The flexible layout allows for efficient operations while benefiting from a vibrant, amenity-rich urban setting. Positioned just minutes from Union Square and the Financial District, the property offers excellent accessibility, strong surrounding demographics, and immediate proximity to public transportation, dining, retail, and major employment centers.

Property Type:

Retail

Date on Market:

2026-05-04

San Francisco Office for Lease - Mission/Potrero

Large, Glass Storefront Facade Great Visibility and Signage Opportunity Ideally Located on 14th Off Bustling Guerrero St Accessible via Public Transportation, Direct Freeway Access Four (4) Large Private Offices Kitchenette New Paint and Electrical Shared Backyard Garden with a Seating Area

Property Type:

Retail

Date on Market:

2026-04-30

San Francisco Retail for Lease - Waterfront/North Beach

Located in the North Beach neighborhood of San Francisco, the subject space is situated in a high density location.

Date on Market:

2026-04-24

San Francisco Retail for Lease - Mission/Potrero

Discover the vibrant energy of one of San Francisco's most sought-after neighborhoods around the property. Located in the trendy Mission District, this bustling area is home to a diverse mix of boutique shops, gourmet restaurants, SF General Hospital, and trendy cafes. The property benefits from prime foot traffic, thanks to its proximity to popular landmarks like Dolores Park, SF Public Library, City College of SF, Mission Cultural Center, and more. Public transportation (Muni, BART, buses) and US-101 and I-280 freeways nearby. With its unique blend of art, culture, and culinary delights, the area offers an exciting opportunity for a Retail/Street Retail tenant to immerse themselves in the dynamic fabric of San Francisco's eclectic community. This building features a warehouse and retail storefront on the ground level, with a 1 bedroom/1 bath unit conveniently built above the retail space. This versatile property offers a range of possibilities for investors, developers, and owner-users seeking a mixed-use investment opportunity in a prime San Francisco location. Available for in-person tour: Mon-Fri 8AM-3PM. Contact Broker to schedule.

Date on Market:

2026-04-14

San Francisco Office for Lease - Financial District

686 Sacramento presents a rare leasing opportunity in the heart of San Francisco’s historic Financial District. This well maintained second-floor office suite offers approximately 2,200 square feet of thoughtfully designed workspace that blends character with modern functionality. The space features soaring ceilings, expansive windows, and abundant natural light throughout, creating an open and energizing work environment. The layout includes a large collaborative open area, four private offices or conference rooms, a fully equipped kitchen and pantry, and two restrooms — one of which includes a shower for added convenience. Ideal for offices seeking a distinctive, move-in-ready space in a premier downtown location, 686 Sacramento delivers both presence and practicality in one exceptional offering. $7,500 Per Month + NNN • Approximately 2,200 Sq. Ft. • Large Open Concept. • 4 Private Offices. • 2 Restrooms (Including 1 Shower). • Pride of Ownership – Well Maintained Including Hardwood Floors, Air Conditioning, and High Ceilings. • Lots of Natural Light. • Ideally Located in SF’s Bustling Financial District. San Francisco’s Financial District is the city’s premier business address—where global commerce meets iconic architecture and a dynamic urban lifestyle. Anchored by landmarks such as the Transamerica Pyramid and Embarcadero Center, the district’s skyline is instantly recognizable and synonymous with innovation, influence, and opportunity. Home to major financial institutions, Fortune 500 companies, venture capital firms, and leading law practices, the Financial District offers unparalleled access to decision-makers and industry leaders. Its prime location provides immediate connectivity to BART, Muni, ferries, and regional highways—making it one of the most accessible commercial hubs in the Bay Area. The neighborhood also delivers an exceptional work-life environment. From Michelin-starred dining and upscale cafés to luxury hotels and waterfront views along the Embarcadero, the Financial District blends professional prestige with vibrant city energy. For companies seeking visibility, credibility, and connectivity, San Francisco’s Financial District remains the gold standard in Northern CA.

Property Type:

Retail

Date on Market:

2020-07-09