21 Storefront Properties for Lease in San Mateo, CA, USA

Belmont Flex, Industrial for Lease - Belmont/San Carlos

Goodman Innovation Center Belmont at 260-450 Harbor Boulevard provides creative office and flexible research and development (R&D) spaces on a premier campus setting with scalability for future growth. Under new ownership, Goodman is planning renovations to convert the dated business park known as Harbor Park to a state-of-the-art multi-tenant campus for the San Francisco Peninsula’s premier med-tech, food tech, green and sustainability companies, vehicle and battery tech, and R&D tenants looking for a strong sense of place to retain and recruit the next generation of talent. The major campus renovation in progress will add outdoor amenity areas, extensive interior renovations, and vacant suites ranging from 2,363 to 41,271 square feet. Goodman Innovation Center Belmont offers abundant on-site parking and unrivaled motorway connectivity with direct access to the 101, 92, and 280 Freeways. Additionally, this modern campus is strategically situated just one mile from the San Carlos Caltrain Station. The San Francisco International Airport is 10.7 miles away for business travel needs, and the San Jose Airport is 24.4 miles away. Set within the desirable San Francisco Peninsula, employees will appreciate the proximity to restaurants, retailers, gyms, child care facilities, and daily convenience amenities. Given the premier address in Belmont, tenants can reach more than six million people within a one-hour drive time, presenting ideal opportunities for a variety of creative, light industrial, bulky goods storage, and distribution users. With Stanford University only 11 miles away, companies also enjoy access to a highly educated workforce. For businesses in need of a large potential consumer base and workforce, easy access throughout San Francisco, and convenient paths for on-site expansion (with existing leases on the campus rolling over in the next 10+ years), look no further than Goodman Innovation Center Belmont.

Date on Market:

2025-08-04

Belmont Office/Retail for Lease - Belmont/San Carlos

Located along El Camino Real, this transit-oriented development features over 10,000 sq ft of mixed-use retail/commercial space on the ground level, 32 luxury residential condominiums, and above and underground parking.

Property Type:

Retail

Date on Market:

2020-07-30

San Mateo Office/Medical for Lease

Recently renovated 3 room suite ideal for office/medical/dental. Formerly occupied by Westside Chiropractic prior to office downsize. Newly updated electrical panel and tankless water heater.

Property Type:

Retail

Date on Market:

2026-02-25

San Mateo Retail for Lease

Commercial Retail Building built in 1926 located on the corner of Baldwin & N. Elsworth. This location in downtown San Mateo offers maximum foot traffic and good access to transportation. The retail space has good visibility from the street with big plate glass store front windows. 277 Baldwin is a two story retail space: 795 ground floor space with restroom in the back and a 400 sq. ft. mezzanine upstairs with a closet. Total rentable square footage is 1,195 sq. ft.

Date on Market:

2026-02-18

San Mateo Retail for Lease

Date on Market:

2026-02-13

San Mateo Retail for Lease

SC Properties is pleased to present a prime office/retail opportunity located in the heart of booming Downtown San Mateo. Positioned within walking distance to Caltrain, popular restaurants, cafés, retail shops, and daily conveniences, this location offers exceptional visibility and accessibility. The space features an efficient open floor plan that can easily accommodate a variety of uses, including professional office, boutique retail, service-based businesses, or showroom space. Large storefront windows provide excellent natural light. The unit also includes a private restroom and room for storage. With immediate access to Highways 101, 92, and 280, the property is well-connected for commuters traveling throughout the Peninsula and greater Bay Area. Ample surrounding street parking further enhances accessibility for clients and staff. Offered at a very competitive rate, this is an outstanding opportunity for businesses seeking a short-term lease in a highly desirable Downtown San Mateo location. The flexible lease term provides an ideal solution for growing companies, seasonal users, or businesses looking to establish a presence in a premier corridor without a long-term commitment.

Date on Market:

2026-02-10

San Mateo Retail for Lease

Property Type:

Office

Date on Market:

2026-02-05

Burlingame Retail for Lease

Date on Market:

2026-01-19

Burlingame Retail for Lease

3,850 SF available! 1420 Burlingame Avenue represents the opportunity to lease prime retail space on desirable Burlingame Avenue in thriving Downtown Burlingame. Burlingame Avenue recently underwent an extensive street scape renovation further improving the downtown core. Highly desirable Burlingame Avenue location! Blocks to the Burlingame Ave Caltrain station. Short drive to highways 101, 92, 280, and SFO. Property website link: http://www.1422bgameave.com

Date on Market:

2025-02-21

Burlingame Office, Retail for Lease

Two story commercial building with adjacent parking lot. Located adjacent to the Broadway corridor, positioning the building close to highway 101 and the Broadway Burlingame Caltrains Station, which may become a fulltime stop in Q4 of 2024.

Date on Market:

2024-04-18

San Mateo Office for Lease

250 Main St is located in the heart of downtown San Mateo with 1,340 sqft of studio space & storefront glass. Includes secured storage, a private office and a Bathroom. The unit shares a secured & alarmed lobby with 1 other unit as shown in the floor plan. NNN $0.81 psf/month Base Rent $2.57 psf/month Please do not hesitate to reach out with inquiries, questions or showing availabilities!

Property Type:

Retail

Date on Market:

2025-01-24

Belmont Retail for Lease - Belmont/San Carlos

Former Walgreens. All offers are subject to approval by Walgreens Real Estate Committee. Lease end date is 8/31/28.

Date on Market:

2024-12-18

San Mateo Office/Retail for Lease

NNN costs approximately ±$0.85 PSF/MO Prime commercial lease opportunity in Downtown San Mateo, fantastic location across from Central Park! Approximately ±845 square feet of space, office/retail/personal services, currently built out as a hair salon. High visibility in a vibrant downtown setting with high pedestrian foot traffic and prominent signage opportunities. An impressive 99 WalkScore, this location in Downtown San Mateo has something for everyone. Walking distance to quaint boutique shopping, trendy cafes, entertainment and amenities. A host of lively restaurants offering a blend of culture, cuisine, and community, an established and growing culinary scene with award winning dining and local favorites. Close proximity to endless dining and Michelin-starred restaurants, boutique shopping, Transit oriented location, convenient access to public transportation. Easy access to Caltrain (6 blocks away), SamTrans bus service, BART (Bay Area Rapid Transit) and the San Francisco International Airport (SFO), all within minutes of Downtown San Mateo. Located in the heart of the Bay Area, Downtown San Mateo is in a strategic location and currently undergoing an exciting transformation with new opportunities! Position your business in a neighborhood that's not only immersed in history but also embracing a future of growth and prosperity. Interested parties to verify their business type with the City of San Mateo Planning Department, All information deemed accurate but not guaranteed, subject to change at any time, Broker/Agent does not assume legal responsibility for omissions or errors.

Property Type:

Retail

Date on Market:

2024-06-19

San Mateo Office for Lease

Experience modern work comfort in our2nd-floor office suites, bathed in abundant natural light. Enjoy an open space layout ideal for dynamic collaboration, all situated in the heart of downtown San Mateo.

Property Type:

Retail

Date on Market:

2024-02-15

San Mateo Office for Lease

$1,900 per month - Rare Individual private office space 650 sq. ft. Second-Floor– Recently Remodeled Bright and open 650 sq. ft. second-floor office with abundant natural light and a versatile open floorplan. Space includes two (2) reserved off-street parking spaces, air conditioning, and 24-hour secured access. Recently updated with modern finishes, this office is ideal for a professional user seeking a clean, efficient, and well-located workspace with convenient access to nearby amenities and major thoroughfares.

Property Type:

Retail

Date on Market:

2025-09-18

San Mateo Office/Retail for Lease

Rate and terms are NEGOTIABLE for High Credit and established Tenants. 1743 1745 S. El Camino Real , San Mateo, CA, Fully Sprinklered, Main building is Reinforced concrete with Elevator, Zoning: C3-1/R4 (FAR:2; 45-55 height) Verify with San Mateo City planning, CORNER Lot @ NE Corner of Hwy 92 and El Camino Real, with traffic light controlled intersection * *highly visible location w/ El Camino Real frontage *SUITABLE FOR RETAIL, SHOWROOM, OFFICE, EDUCATION SVC *1ST & 2ND FLOOR COULD ACCOMMODATE Separate businesses. Lot: ~17,500 +/-sq.ft: Approx. 100 ft +/-on El Camino Real, 60 ft +/-on Ivy St & 18th Ave. corner, ~13,195 SF BUILDING TWO FLOORS Available now-1stfloor: ~6000+/-SF concrete-2ndfloor: ~6000+/-SF concrete-Warehouse w/ loading dock& driveway~1195 SF wood structure. Steps from Starbucks, Safeway, Banks & other amenities *Across street from Borell Shopping Center. About 5 +/-min. drive to College of San Mateo and Downtown San Mateo. 2 +/-miles to Hillsdale Mall ?0.4 mile/15min walk to Caltrain 30 min to San Francisco, 15 min to SFO airport. 15 min to Palo Alto & Stanford, 45 min to San Jose. HIGH CEILINGS, * 1stfloor NEW track lighting w/dimmers, First floor heater and 2ndfloor HVAC Full sprinklers with 24/7 monitoring. Lined for 30 parking spaces Large tree lined fenced parking lot w/ ADA ramp Secure Gated lot & parking area. Large Elevator to 2ndfloor & roof (potential roof deck) ?Composition Roof *** SIGNAGE & BUSINESS IDENTITY HIGHLY VISIBLE

Property Type:

Retail

Date on Market:

2022-08-03

San Mateo Office/Medical for Lease

Excellent mixed use building on 25th Ave. with parking and elevator access. Many uses considered!

Property Type:

Retail

Date on Market:

2021-06-25

Belmont Office/Retail, Retail for Lease - Belmont/San Carlos

- Frontage along busy El Camino Real with two curb cuts - Parking spaces in shopping center

Date on Market:

2023-10-24

San Mateo Retail for Lease

Located in the vibrant heart of Downtown San Mateo, 55 E 4th Avenue offers a prime retail opportunity within one of the Peninsula’s most dynamic commercial districts. This ±1,250 SF second-generation salon space is ideally suited for beauty, wellness, or boutique retail concepts seeking immediate functionality and strong foot traffic. The property benefits from Central Business District (CBD) zoning, allowing for a variety of retail and service uses, making it a flexible option for operators looking to establish a presence in a high-demand market. Downtown San Mateo is a thriving hub with strong demographics: over 144,000 residents within three miles and an average household income exceeding $245,000. The area’s daytime population of more than 172,000 supports robust retail activity, while traffic counts along El Camino Real reach 30,000 ADT. This property delivers a rare opportunity to secure a turnkey retail space in a high-visibility corridor surrounded by established brands and dense residential neighborhoods.

Date on Market:

2026-02-26

San Mateo Office/Retail for Lease

Property Type:

Retail

Date on Market:

2025-12-08

San Mateo Retail for Lease

Retail Building with Excellent Location In Downtown San Mateo. Prominent Signage Opportunities. Surrounded By Countless Downtown Restaurants & Amenities. Easily Accessible Via El Camino Real & U.S. 101. Walking Distance To CalTrain Station.

Date on Market:

2025-08-15