22 Storefront Properties for Lease in San Mateo, CA, USA

Belmont Flex, Industrial for Lease - Belmont/San Carlos

Goodman Innovation Center Belmont at 260-450 Harbor Boulevard provides creative office and flexible research and development (R&D) spaces on a premier campus setting with scalability for future growth. Under new ownership, Goodman is planning renovations to convert the dated business park known as Harbor Park to a state-of-the-art multi-tenant campus for the San Francisco Peninsula’s premier med-tech, food tech, green and sustainability companies, vehicle and battery tech, and R&D tenants looking for a strong sense of place to retain and recruit the next generation of talent. The major campus renovation in progress will add outdoor amenity areas, extensive interior renovations, and vacant suites ranging from 2,363 to 41,271 square feet. Goodman Innovation Center Belmont offers abundant on-site parking and unrivaled motorway connectivity with direct access to the 101, 92, and 280 Freeways. Additionally, this modern campus is strategically situated just one mile from the San Carlos Caltrain Station. The San Francisco International Airport is 10.7 miles away for business travel needs, and the San Jose Airport is 24.4 miles away. Set within the desirable San Francisco Peninsula, employees will appreciate the proximity to restaurants, retailers, gyms, child care facilities, and daily convenience amenities. Given the premier address in Belmont, tenants can reach more than six million people within a one-hour drive time, presenting ideal opportunities for a variety of creative, light industrial, bulky goods storage, and distribution users. With Stanford University only 11 miles away, companies also enjoy access to a highly educated workforce. For businesses in need of a large potential consumer base and workforce, easy access throughout San Francisco, and convenient paths for on-site expansion (with existing leases on the campus rolling over in the next 10+ years), look no further than Goodman Innovation Center Belmont.

Date on Market:

2025-08-04

Belmont Office/Retail for Lease - Belmont/San Carlos

Located along El Camino Real, this transit-oriented development features over 10,000 sq ft of mixed-use retail/commercial space on the ground level, 32 luxury residential condominiums, and above and underground parking.

Property Type:

Retail

Date on Market:

2020-07-30

Belmont Retail for Lease - Belmont/San Carlos

Positioned along the highly trafficked El Camino Real corridor in Belmont, this retail opportunity offers approximately ±1,600 square feet across both the ground floor and basement levels. The space features a modern retail buildout with upgraded lighting, expansive storefront windows, and excellent street frontage, creating a bright and welcoming environment for customers and clients alike. The versatile layout allows for a variety of retail or service- oriented uses, while the large basement area provides additional flexibility for inventory storage, creative workspace, or operational support. Located within one of the Peninsula’s most established commercial corridors, the property benefits from strong visibility, convenient accessibility, and consistent daily traffic exposure.

Date on Market:

2026-05-17

Burlingame Retail for Lease

755 SF available! 1412 Burlingame Avenue represents the opportunity to lease prime retail space on desirable Burlingame Avenue in thriving Downtown Burlingame. The space features +/- 15 ft. ceilings, one restroom and ample storage space. Burlingame Avenue recently underwent an extensive street scape renovation further improving the downtown core. Highly desirable Burlingame Avenue location! Blocks to the Burlingame Ave Caltrain station. Short drive to highways 101, 92, 280, and SFO.

Property Type:

Flex

Date on Market:

2026-05-14

Burlingame Office/Medical for Lease

Property Type:

Retail

Date on Market:

2026-04-17

San Mateo Retail for Lease

Date on Market:

2026-03-27

San Mateo Retail for Lease

Ground Floor 1500 sf corner retail space in mixed use building on high traffic count El Camino Real corridor in San Mateo

Date on Market:

2026-03-25

Belmont Retail for Lease - Belmont/San Carlos

Date on Market:

2026-03-12

San Mateo Office/Retail, Retail for Lease

709-711 S B Street presents a rare opportunity to acquire a historic two-story commercial building near Downtown San Mateo. The property consists of approximately 5,005 square feet and is configured with two separate units, offering flexibility for an owner-user, investor, or redevelopment buyer. The ground floor (Suite 709) was formerly operated as Yuppie Cantina, featuring an existing bar and kitchen buildout along with a private fenced backyard patio area, making it well suited for a restaurant, bar, or hospitality concept. The second floor (Suite 711) was previously occupied by School of Rock and offers a wide-open layout, high ceilings, and excellent natural light, creating an ideal setting for creative office, fitness studio, music/arts education, or collaborative workspace. The property benefits from C1 (Neighborhood Commercial District)-R5 zoning, allowing a variety of commercial and mixed-use possibilities, including potential retail, office, service, or residential integration (buyer to verify). Positioned just south of Downtown San Mateo, the property is surrounded by dense residential neighborhoods, restaurants, and retail amenities, offering strong long-term repositioning potential.

Date on Market:

2026-03-10

Burlingame Retail for Lease

Multi-tenant w/ 1 retail/office suite and 2 Apartment Units.

Date on Market:

2026-03-05

Burlingame Retail for Lease

Located on the heart of Burlingame Avenue, 1223 Burlingame Avenue presents a rare opportunity to lease space along one of the Peninsula’s most established and walkable retail corridors. The property benefits from consistent pedestrian traffic, strong surrounding demographics, and immediate proximity to both national retailers and high quality local concepts.

Date on Market:

2026-01-19

Burlingame Retail for Lease

3,850 SF available! 1420 Burlingame Avenue represents the opportunity to lease prime retail space on desirable Burlingame Avenue in thriving Downtown Burlingame. Burlingame Avenue recently underwent an extensive street scape renovation further improving the downtown core. Highly desirable Burlingame Avenue location! Blocks to the Burlingame Ave Caltrain station. Short drive to highways 101, 92, 280, and SFO. Property website link: http://www.1422bgameave.com

Date on Market:

2025-02-21

San Mateo Office/Retail for Lease

NNN costs approximately ±$0.85 PSF/MO Prime commercial lease opportunity in Downtown San Mateo, fantastic location across from Central Park! Approximately ±845 square feet of space, office/retail/personal services, currently built out as a hair salon. High visibility in a vibrant downtown setting with high pedestrian foot traffic and prominent signage opportunities. An impressive 99 WalkScore, this location in Downtown San Mateo has something for everyone. Walking distance to quaint boutique shopping, trendy cafes, entertainment and amenities. A host of lively restaurants offering a blend of culture, cuisine, and community, an established and growing culinary scene with award winning dining and local favorites. Close proximity to endless dining and Michelin-starred restaurants, boutique shopping, Transit oriented location, convenient access to public transportation. Easy access to Caltrain (6 blocks away), SamTrans bus service, BART (Bay Area Rapid Transit) and the San Francisco International Airport (SFO), all within minutes of Downtown San Mateo. Located in the heart of the Bay Area, Downtown San Mateo is in a strategic location and currently undergoing an exciting transformation with new opportunities! Position your business in a neighborhood that's not only immersed in history but also embracing a future of growth and prosperity. Interested parties to verify their business type with the City of San Mateo Planning Department, All information deemed accurate but not guaranteed, subject to change at any time, Broker/Agent does not assume legal responsibility for omissions or errors.

Property Type:

Retail

Date on Market:

2024-06-19

San Mateo Office for Lease

Experience modern work comfort in our2nd-floor office suites, bathed in abundant natural light. Enjoy an open space layout ideal for dynamic collaboration, all situated in the heart of downtown San Mateo.

Property Type:

Retail

Date on Market:

2024-02-15

San Mateo Office/Retail for Lease

Rate and terms are NEGOTIABLE for high-credit and established tenants. The property offers approximately 5,850 square feet on the first floor, fully sprinklered and constructed with reinforced concrete. Zoning is C3-1/R4 (FAR: 2; 45–55 ft height), subject to verification with San Mateo City Planning. This highly visible corner lot is located at the northeast corner of Hwy 92 and El Camino Real, at a traffic light-controlled intersection, providing excellent exposure and accessibility. The first floor features high ceilings, new track lighting with dimmers, and a dedicated heating system. It is suitable for retail, showroom, office, or education service uses. The site includes a large, tree-lined, fenced parking lot with an ADA ramp, secure gated access, and lined parking for approximately 30 vehicles. Full sprinkler system with 24/7 monitoring is in place. The property sits on a lot of approximately 17,500 square feet with about 100 feet of frontage on El Camino Real and 60 feet on Ivy Street and 18th Avenue. Located steps from Starbucks, Safeway, banks, and other amenities, it is across from Borell Shopping Center and within a 5-minute drive to College of San Mateo and Downtown San Mateo. Hillsdale Mall is about 2 miles away, Caltrain is 0.4 miles (15-minute walk), and the site offers convenient access to San Francisco (30 min), SFO Airport (15 min), Palo Alto and Stanford (15 min), and San Jose (45 min). Signage and business identity opportunities are highly visible from El Camino Real.

Property Type:

Retail

Date on Market:

2022-08-03

San Mateo Office/Medical for Lease

Excellent mixed use building on 25th Ave. with parking and elevator access. Many uses considered!

Property Type:

Retail

Date on Market:

2021-06-25

Belmont Office/Retail, Retail for Lease - Belmont/San Carlos

- Frontage along busy El Camino Real with two curb cuts - Parking spaces in shopping center

Date on Market:

2023-10-24

Burlingame Office/Retail for Lease

The property at 1108-1112 Burlingame Ave consists of a mixed-use retail and office building comprising 23,976 square feet. Built in 1940 and renovated in 1997, the property is in Downtown Burlingame and offers direct access to local retail and dining establishments. The location is within 0.2 miles of a Caltrain station and approximately 4.7 miles from San Francisco International Airport. The surrounding transportation network includes Highways 101 and 82, providing connectivity throughout the San Francisco Peninsula.

Property Type:

Retail

Date on Market:

2026-04-23

San Mateo Retail for Lease

Located in the vibrant heart of Downtown San Mateo, 55 E 4th Avenue offers a prime retail opportunity within one of the Peninsula’s most dynamic commercial districts. This ±1,250 SF second-generation salon space is ideally suited for beauty, wellness, or boutique retail concepts seeking immediate functionality and strong foot traffic. The property benefits from Central Business District (CBD) zoning, allowing for a variety of retail and service uses, making it a flexible option for operators looking to establish a presence in a high-demand market. Downtown San Mateo is a thriving hub with strong demographics: over 144,000 residents within three miles and an average household income exceeding $245,000. The area’s daytime population of more than 172,000 supports robust retail activity, while traffic counts along El Camino Real reach 30,000 ADT. This property delivers a rare opportunity to secure a turnkey retail space in a high-visibility corridor surrounded by established brands and dense residential neighborhoods.

Date on Market:

2026-02-26

San Mateo Office for Lease

250 Main St is located in the heart of downtown San Mateo with 1,340 sqft of studio space & storefront glass. Includes secured storage, a private office and a Bathroom. The unit shares a secured & alarmed lobby with 1 other unit as shown in the floor plan. NNN $0.81 psf/month Base Rent is negotiable Please do not hesitate to reach out with inquiries, questions or showing availabilities!

Property Type:

Retail

Date on Market:

2025-01-24

San Mateo Office/Retail, Retail for Lease

Retail Building with Excellent Location In Downtown San Mateo. Prominent Signage Opportunities. Surrounded By Countless Downtown Restaurants & Amenities. Easily Accessible Via El Camino Real & U.S. 101. Walking Distance To CalTrain Station.

Date on Market:

2026-03-25

San Mateo Flex for Lease

Property Type:

Retail

Date on Market:

2026-04-29