39 Warehouses for Lease in South San Francisco, CA, USA

South San Francisco Industrial for Lease

ReadySpaces South San Francisco – Spruce offers flexible warehouse, industrial, and storage units ranging from 250 to 5,000 sq. ft., designed for growing businesses. Located in a vibrant small business community, our spaces scale with your needs—expand or downsize with ease. Enjoy 24/7 access and all-inclusive amenities, including: • Community loading docks • On-site forklifts • Building-wide Wi-Fi • Conference rooms & private offices • CCTV security • Flat monthly pricing—no hidden fees Just minutes from SFO and the Port of Oakland, with quick access to I-380, I-280, Route 101, and Highway 82. Schedule a tour today. Brokers earn full market commission on signed leases.

Date on Market:

2026-03-30

South San Francisco Industrial for Lease

Positioned in the heart of South San Francisco’s thriving industrial corridor, 250 S Maple Avenue offers a rare opportunity to lease high-functioning office and warehouse units tailored for logistics and light manufacturing uses. The property features multiple suites ranging from 2,485 to 2,970 square feet, with options to combine for larger footprints. Each unit is equipped with 18-foot clear heights, drive-in doors, and dedicated parking, ensuring operational efficiency and ease of access. 250 S Maple Avenue is strategically located near major thoroughfares, including Highway 101 and Interstates 280 and 380, and offers direct access to San Francisco International Airport. Additionally, the property is within walking distance of the San Bruno BART Station. This site is just minutes from regional retail hubs like The Shops at Tanforan and San Bruno Towne Center. The property’s positioning on South Maple Avenue enhances visibility and accessibility, while tenant improvement allowances provide flexibility for customization.

Date on Market:

2025-11-13

South San Francisco Office, Flex for Lease

Office and Flex/Industrial business park located in South San Francisco, CA.

Date on Market:

2025-08-01

South San Francisco Industrial for Lease

Date on Market:

2026-04-15

South San Francisco Industrial for Lease

Date on Market:

2026-04-01

South San Francisco Office/Medical for Lease

Prime Medical Office Opportunity Exceptional opportunity to acquire a well-located medical office building in the heart of South San Francisco’s established commercial corridor. Positioned on high-visibility Grand Avenue, this property benefits from strong pedestrian traffic, nearby retail amenities, and convenient access to Highway 101, I-280, BART, and SFO. The building offers a functional medical layout with reception area, private exam rooms, administrative offices, and support space. Ideal for owner-users seeking to control occupancy costs or investors looking to reposition or lease in a high-demand medical market. Surrounded by established businesses, residential neighborhoods, and biotech campuses, this location provides strong patient accessibility and long-term upside. A rare opportunity to secure medical office space in one of the Peninsula’s most supply-constrained submarkets.

Property Type:

Office

Date on Market:

2026-03-23

South San Francisco Industrial for Lease

2,000 square feet of office space. Private Bathroom Kitchenette Comes with 4 parking spaces

Date on Market:

2026-03-18

South San Francisco Industrial for Lease

138 West Harris Avenue is a freestanding commercial building that combines modern office space with practical warehouse functionality. The property encompasses approximately 9,764 square feet, with roughly half of the area dedicated to recently remodeled office suites designed for comfort and productivity. The warehouse portion features a large drive-in door, allowing for efficient logistics and operations, and is equipped with heavy power to support a variety of industrial needs. The building stands alone on its lot, offering a private parking area at the front for employees and visitors. Its location, just east of Highway 101 and less than four miles from San Francisco International Airport, provides excellent access to major transportation routes and nearby amenities such as hotels and conference centers. This versatile building is ideal for businesses seeking a blend of contemporary office space and robust warehouse capabilities in a strategic South San Francisco setting.

Date on Market:

2025-11-17

South San Francisco Industrial for Lease

This industrial property at 149-151 S Linden Avenue offers a highly functional yard and warehouse configuration in the heart of South San Francisco’s industrial corridor. The site spans approximately one acre and includes a ±3,500 SF maintenance warehouse with 20-foot clear height, two 12x12 drive-in doors, and 400 amps of 480V 3-phase power. The lot is newly paved, fully secured, and equipped with ample lighting, providing a safe and efficient environment for operations

Date on Market:

2025-11-04

South San Francisco Industrial for Lease

Date on Market:

2025-10-06

South San Francisco Industrial for Lease

Date on Market:

2025-09-24

South San Francisco Industrial for Lease

4,600 square feet of warehouse space 2,400 square feet of office space 2,279 square feet of mezzanine space 3,900 square feet private rear yard 2,100 square feet side yard Security Gate

Date on Market:

2025-08-06

South San Francisco Office for Lease

Top Floor Office Space for Lease – 301 Grand Ave, South San Francisco ±3,689 SF | Prime Downtown Location Position your business at the heart of Downtown South San Francisco with this exceptional top floor office suite. Located on a prominent corner at 301 Grand Avenue, this ±3,689 sq/ft space offers abundant natural light and a flexible layout featuring multiple private offices, conference rooms, and private restrooms. This premier suite is located in a highly walkable, business-friendly neighborhood, surrounded by a vibrant mix of shops, restaurants, and amenities. It includes on-site elevator access, and is ideally positioned with easy access to Highways 101 and 280, just minutes from San Francisco International Airport, and walking distance to Caltrain and other public transit options. Ideal for professional, creative, or medical office use, this centrally located space offers unparalleled convenience and visibility. Contact us today to schedule a tour!

Date on Market:

2025-06-23

South San Francisco Industrial for Lease

Date on Market:

2025-06-19

South San Francisco Industrial for Lease

Date on Market:

2025-06-19

South San Francisco Industrial for Lease

Date on Market:

2025-03-25

South San Francisco Industrial for Lease

Date on Market:

2025-03-20

South San Francisco Industrial for Lease

Date on Market:

2025-02-24

South San Francisco Flex, Industrial for Lease

Date on Market:

2025-07-23

South San Francisco Industrial for Lease

Date on Market:

2024-12-10

South San Francisco Industrial for Lease

Date on Market:

2024-10-03

South San Francisco Industrial for Lease

Available Now! Total Rent: $1.75 PSF per Month Gross based on Ground Floor Suite Size: ±5,762 SF Total (±4,800 SF Ground Floor, ±962 SF Mezzanine) Condominium can be used for Clean Technology, Research and Development, Handicraft / Custom Manufacturing, Maintenance and Repair Services, etc. Zoning: BTP-M (Business Technology Park-Medium) Close to Costco, The Shops at Tanforan, Marshall’s, Lowe’s, San Francisco International Airport

Date on Market:

2025-11-11

South San Francisco Industrial for Lease

Date on Market:

2026-02-05

South San Francisco Industrial for Lease

Date on Market:

2025-02-03