Commercial Real Estate in South Carolina available for sale
1031 Exchange Properties For Sale

1031 Exchange Properties for Sale in South Carolina, USA

More details for 1376 Red Bluff Rd, Loris, SC - Retail for Sale

Dollar General-N. Myrtle Beach/Loris, SC SC31 - 1376 Red Bluff Rd

Loris, SC 29569

  • 1031 Exchange Property
  • Retail for Sale
  • $3,441,984 CAD
  • 10,566 SF
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More details for 111 State Park Rd, Greenville, SC - Retail for Sale

111 State Park Rd

Greenville, SC 29609

  • 1031 Exchange Property
  • Retail for Sale
  • $1,626,823 CAD
  • 2,336 SF
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More details for 801 N Fant St, Anderson, SC - Retail for Sale

AnMed Urgent Care - 801 N Fant St

Anderson, SC 29621

  • 1031 Exchange Property
  • Retail for Sale
  • $5,801,180 CAD
  • 7,020 SF

Anderson Retail for Sale - Anderson County

-??2% Broker Buyside Co-op Fee -?Very Rare On-Campus Hospital Leased Investment Opportunity - On-campus properties are usually owned by health systems or large institutional investors, however, this listing offers the rare opportunity to acquire a specialized on-campus single-tenant hospital leased medical office building. AnMed Urgent Care (a subsidiary of the AA- credit rated AnMed) is located on the campus of the flagship 461-bed AnMed Medical Center in Anderson, South Carolina. ??-Significant Pro Forma Upside & Irreplaceable/Strategic Location - The current lease has ~5 years of firm term remaining (expires 3/6/2031) and then the tenant has 1-15 year option at market rent. The property's current rent of $35.81/SF NNN, is well below the recent market average for comparable highly specialized urgent care facilities (~$55/SF NNN). ?-Highly Specialized Facility | Priced Well Below Replacement Cost - Built in 2014 (Class A construction) and AAAHC-accredited, the subject property is a highly specialized purpose-built facility. The property's pricing at $597/SF, is additionally well below the recent market average for comparable specialized urgent care facilities ($850/SF). ?-Rapidly Growing & Attractive Market - This property is situated in the rapidly growing Upstate Region of South Carolina, in the geographical center of the Charlanta Megaregion (~22M population & ~$1T of annual economic output). The building is additionally located in an extremely attractive healthcare submarket, which features 100% medical office building occupancy within a 3 mile radius (724K total MOB SF).

Contact:

Acuity Private Capital

Property Subtype:

Freestanding

Date on Market:

2026-05-12

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More details for 2475 Ashley River Rd, Charleston, SC - Land for Sale

2475 Ashley River Road - 2475 Ashley River Rd

Charleston, SC 29414

  • 1031 Exchange Property
  • Land for Sale
  • $1,502,215 CAD
  • 3.90 AC Lot
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More details for 400 N Main St, Hemingway, SC - Retail for Sale

Advance Auto Store - 400 N Main St

Hemingway, SC 29554

  • 1031 Exchange Property
  • Retail for Sale
  • $1,675,281 CAD
  • 7,000 SF
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More details for 1650 Dusty Rd, Newberry, SC - Specialty for Sale

Turnkey Winery & Event Estate - 1650 Dusty Rd

Newberry, SC 29108

  • 1031 Exchange Property
  • Specialty for Sale
  • $2,769,060 CAD
  • 4,243 SF
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More details for 206 S Main St, Hemingway, SC - Retail for Sale

CVS Pharmacy - 206 S Main St

Hemingway, SC 29554

  • 1031 Exchange Property
  • Retail for Sale
  • $1,813,734 CAD
  • 10,710 SF
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More details for 2221 Chesnee Hwy, Spartanburg, SC - Retail for Sale

2221 Chesnee Hwy

Spartanburg, SC 29303

  • 1031 Exchange Property
  • Retail for Sale
  • $2,198,080 CAD
  • 3,165 SF
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More details for 816 Shull St, West Columbia, SC - Multifamily for Sale

816 Shull St

West Columbia, SC 29169

  • 1031 Exchange Property
  • Multifamily for Sale
  • $1,938,342 CAD
  • 4,800 SF
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More details for 4 - Turnkey - Short term rental homes – Land for Sale, Myrtle Beach, SC

4 - Turnkey - Short term rental homes

  • 1031 Exchange Property
  • Land for Sale
  • $3,738,231 CAD
  • 0.04 AC
  • 4 Land Properties
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More details for 0 King Rail Lane, Edisto Island, SC - Land for Sale

0 Highway 174 Development opportunity - 0 King Rail Lane

Edisto Island, SC 29438

  • 1031 Exchange Property
  • Land for Sale
  • $2,623,684 CAD
  • 34.73 AC Lot

Edisto Island Land for Sale - W Charleston County

Just 2.5 miles from the pristine sandy shores of Edisto Beach, this extraordinary 34.7-acre estate unfolds beneath a canopy of centuries-old live oaks. From the moment you enter the private drive, towering live oaks draped in Spanish moss create a cathedral-like canopy overhead. The landscape feels curated by nature itself -- Sunlight filters through sweeping branches, illuminating curated clearings, winding internal roadways, and filtered sunlight dancing across the acreage. It is rare to find property this cinematic, this private, and this close to the ocean. Comprising six individual tax parcels, the property balances natural beauty with strategic flexibility-a combination increasingly scarce in established coastal markets.A quiet non-tidal creek winds through portions of the acreage, enhancing both exclusivity and ecological richness. With the mixture of wetlands and undisturbed nature, the land feels preserved, intentional, and rare. With multiple homesites throughout the acreage the possibilities are endless. The configuration of the six parcels allows for multiple pathways forward: preservation as a singular legacy estate, creation of a multi-generational compound, or selective release of estate-sized homesites over time, the opportunities are both practical and valuable--- On Edisto Island, properties like this are no longer created - only discovered and in a coastal paradise where scarcity drives value, opportunities of this magnitude are seldom repeated. Only minutes away from the sand and less than an hour to Charleston, this estate offers the rare ability to live expansively while remaining connected to the relaxed elegance of Edisto's coastal lifestyle. It is both residence and reserve. Both retreat and asset. This is a must see! *Seller financing available. Qualified buyers may assume existing seller note via novation with seller approval.

Contact:

Home Advantage Realty Lowcountry

Property Subtype:

Residential

Date on Market:

2026-03-30

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More details for 1090 S Main St, South Congaree, SC - Retail for Sale

Dollar General I High Traffic I Columbia MSA - 1090 S Main St

South Congaree, SC 29170

  • 1031 Exchange Property
  • Retail for Sale
  • $1,141,538 CAD
  • 9,100 SF
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More details for 203 Caulder Cir, Spartanburg, SC - Specialty for Sale

203 Caulder Cir

Spartanburg, SC 29306

  • 1031 Exchange Property
  • Specialty for Sale
  • $407,052 CAD
  • 26,136 SF
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More details for 59 Broad St, Charleston, SC - Office for Sale

Downtown Charleston Mixed-Use Redevelop Opp. - 59 Broad St

Charleston, SC 29401

  • 1031 Exchange Property
  • Office for Sale
  • $3,669,004 CAD
  • 4,923 SF
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More details for 163 Old Buncombe Rd, Union, SC - Specialty for Sale

Cross Keys - 163 Old Buncombe Rd

Union, SC 29379

  • 1031 Exchange Property
  • Specialty for Sale
  • $1,315,303 CAD
  • 4,100 SF

Union Specialty for Sale - Union County

Historic Cross Keys House National Register Property | Destination Agri-Tourism & Heritage Hospitality Opportunity | Live-Work Estate Investment Highlights • Historic National Register property built between 1812–1814 • Rare opportunity to develop a destination agri-tourism and heritage hospitality business • Ideal live-work estate allowing owner residence with income-producing operations • Existing men’s and women’s restroom facilities already in place for events and visitors • Architectural distinction including rare diamond-pattern Flemish bond brick chimneys • Suitable for weddings, retreats, culinary events, festivals, and heritage tourism programming • Located 10 minutes from Interstate 26, 35 minutes to Spartanburg, and 45 minutes to Greenville-Spartanburg International Airport (GSP) • Authentic rural landscape setting with strong potential for experiential tourism development Property Overview The Historic Cross Keys House presents an extraordinary opportunity to acquire one of the Upstate’s most distinctive historic properties and develop it into a destination rooted in agri-tourism, heritage hospitality, and experiential events. Located in southwestern Union County, South Carolina, the Cross Keys House was constructed between 1812 and 1814 and stands as one of the region’s most architecturally significant historic residences. The property sits within the cultural landscape of the once “large and prosperous” Cross Keys Plantation, which historically served as an important travel stop along early transportation routes linking the South Carolina backcountry with the Lowcountry. Positioned near the historic travel corridors of Old Charleston Road (Old Buncombe Road) and Old Ninety-Six Road (Old Piedmont Stage Road), the property reflects a time when travelers, merchants, and settlers moved through the area on stage routes connecting Charleston with the interior of the state. Today, the Cross Keys House retains the character, scale, and presence that made it a landmark in the early nineteenth century. The property is listed on the National Register of Historic Places, recognizing its architectural significance and its place within the historic landscape of the South Carolina backcountry. Beyond its historic importance, the property offers exceptional potential for adaptive reuse as a hospitality-focused destination. The surrounding acreage, historic architecture, and rural setting create an ideal environment for an owner-operator seeking to establish a venue centered on authentic Southern heritage and experiential tourism. Live-Work Hospitality Opportunity The Cross Keys House provides a rare opportunity for a buyer to live on the property while operating a hospitality or tourism-based enterprise. The site naturally lends itself to a variety of destination-driven uses including: • Wedding and special event venue • Farm-to-table dining experiences and culinary gatherings • Agri-tourism operations and seasonal festivals • Heritage tourism destination and interpretive programming • Retreats, workshops, and educational events • Boutique lodging or bed-and-breakfast concept • Private estate hosting curated gatherings and cultural events A key operational advantage is the presence of existing men’s and women’s restroom facilities, an uncommon feature on historic rural properties. This infrastructure significantly reduces the cost and complexity associated with launching event-based operations and makes the property immediately adaptable for visitor-focused activities. For entrepreneurs seeking to capitalize on the rapidly expanding experiential travel and agri-tourism market, this property offers an authentic environment that cannot be replicated by modern venues. Architectural Significance Architecturally, the Cross Keys House remains an exceptional example of Federal-period architecture in the South Carolina backcountry. The home retains strong historic integrity and numerous character-defining features associated with early nineteenth-century craftsmanship. Most notable is the extremely rare diamond-pattern Flemish bond brickwork found in all four exterior chimneys, a distinctive masonry technique seldom seen in the region. This unusual brick pattern creates a striking visual element and serves as a testament to the skilled craftsmanship present during the early republic period. Architectural details of this caliber significantly enhance the property's historic appeal and reinforce its potential as a heritage tourism destination. The home’s historic presence, combined with the surrounding landscape, creates a setting that continues to evoke the atmosphere experienced by travelers more than two centuries ago. Location & Accessibility While the property offers the tranquility and charm of a historic rural estate, it is also conveniently positioned within reach of several major regional markets. • 10 minutes to Interstate 26 • 35 minutes to Spartanburg • 45 minutes to Greenville-Spartanburg International Airport (GSP) This accessibility allows the property to function effectively as a regional destination venue, capable of attracting guests from across the Upstate, the Charlotte region, and beyond. The combination of rural authenticity and regional connectivity is a key advantage for hospitality or event-driven development. Destination Development Potential The Cross Keys House offers an outstanding platform for developing a heritage-driven tourism destination within one of the fastest growing segments of the hospitality industry: experiential travel. Today’s travelers increasingly seek authentic places with history, character, and cultural meaning rather than conventional commercial venues. Properties like the Cross Keys House provide exactly that experience—an environment where architecture, landscape, and history combine to create a memorable destination. An owner-operator could establish a heritage farm venue or boutique hospitality retreat where visitors gather for weddings, seasonal events, culinary experiences, and educational programming tied to regional agriculture and history. The ability to combine residential living with hospitality operations creates a sustainable business model that blends lifestyle with entrepreneurship. Few historic properties offer this combination of architectural significance, visitor infrastructure, rural setting, and access to major population centers. The Historic Cross Keys House represents a rare opportunity to acquire a landmark property with both historic significance and commercial potential. Whether developed as a heritage hospitality destination, an agri-tourism venue, or a private estate hosting curated events, the property provides the foundation for a truly distinctive place rooted in the cultural landscape of the South Carolina Upstate. For investors, entrepreneurs, and preservation-minded buyers alike, this property offers the chance to create a destination that blends history and commerce.

Contact:

Blackstream Commercial

Date on Market:

2026-03-09

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More details for 714 S Main St, Greenville, SC - Retail for Sale

714 S Main St - West End - 714 S Main St

Greenville, SC 29601

  • 1031 Exchange Property
  • Retail for Sale
  • $3,869,761 CAD
  • 4,300 SF
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More details for 3905 Fernandina Rd, Columbia, SC - Retail for Sale

Prime Highway Retail & Restaurant - 3905 Fernandina Rd

Columbia, SC 29210

  • 1031 Exchange Property
  • Retail for Sale
  • $2,352,316 CAD
  • 9,261 SF
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More details for 81 Simons St, Charleston, SC - Multifamily for Sale

Duplex in North Central Charleston - 81 Simons St

Charleston, SC 29403

  • 1031 Exchange Property
  • Multifamily for Sale
  • $1,176,850 CAD
  • 2,525 SF
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More details for 6750 Pottery Rd, Spartanburg, SC - Retail for Sale

Fatz Cafe - 6750 Pottery Rd

Spartanburg, SC 29303

  • 1031 Exchange Property
  • Retail for Sale
  • $2,076,795 CAD
  • 5,760 SF
  • Air Conditioning
  • 24 Hour Access
  • Wheelchair Accessible

Spartanburg Retail for Sale - Upper Spartanburg County

This is a strong asset offering exceptional exit visibility, direct I-26 exposure, major national co-tenancy, and a rare parking count for the corridor. Former national restaurant location strategically positioned at the signalized Exit 17 interchange of I-26 (New Cut Road), providing outstanding freeway visibility, immediate interstate access, and a dedicated turn lane for seamless ingress and egress. The property consists of a 5,760 SF single-tenant building situated on approximately 2.00 acres, constructed in 2000 with wood frame construction and approximately 16-foot building height. Zoned GC (General Commercial), the site allows for a wide range of commercial uses. The building features approximately 150 parking spaces, existing commercial kitchen infrastructure, storage space, tenant-controlled HVAC, air conditioning, full 24-hour access, ADA accessibility, and prominent signage opportunities. Surrounding national co-tenancy includes McDonald’s, Waffle House, Exxon, Wyndham, Red Roof Inn, and Days Inn, reinforcing the strong interstate commercial environment. Ideal for restaurant conversion, travel center use, medical or retail redevelopment, event venue, church, or high-traffic service operator. The location benefits from heavy interstate traffic, hotel density, and strong regional commercial activity. Vacant and ready for repositioning. Owner-user or redevelopment opportunity.

Contact:

GSP Rental LLC

Property Subtype:

Restaurant

Date on Market:

2026-02-16

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More details for 605 Travis Ave, Saluda, SC - Retail for Sale

Saluda Towne Centre - 605 Travis Ave

Saluda, SC 29138

  • 1031 Exchange Property
  • Retail for Sale
  • $6,309,303 CAD
  • 37,450 SF
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More details for 260 Watson Heritage Rd, Loris, SC - Health Care for Sale

Oaks of Loris Assisted Living Facility - 260 Watson Heritage Rd

Loris, SC 29569

  • 1031 Exchange Property
  • Health Care for Sale
  • $4,152,898 CAD
  • 34,028 SF
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More details for 41 ACRES Hwy 55 Hwy, Clover, SC - Land for Sale

Grier Trust - 41 ACRES Hwy 55 Hwy

Clover, SC 29710

  • 1031 Exchange Property
  • Land for Sale
  • $2,407,421 CAD
  • 41.40 AC Lot
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