10 Breweries for Lease in San Diego, CA, USA

San Diego Retail for Lease - Park East

Available for lease for the first time in over a decade, 4223 30th Street offers a rare opportunity to occupy an iconic ±5,900 SF building in the heart of North Park, San Diego, with an additional ±1,600 SF fenced outdoor patio. The entire building is available for lease, or you can lease individual spaces. Priced at $3.05/SF NNN, this high-profile corner property is one of the city’s most recognizable landmarks, featuring the renowned “Greetings from San Diego” mural. The building showcases glass-panel roll-up doors, exposed wood ceilings, two built-out bars, four restrooms, and 20-foot warehouse ceilings, along with 600-amp 3-phase power and gas service. Formerly home to a brewery tasting room and coffee roastery, it’s ideally suited for a restaurant, bar, distillery, gallery, café, creative workspace, or retail concept. Situated at the intersection of 30th Street and El Cajon Boulevard, the space enjoys exceptional visibility, heavy foot traffic, and proximity to thousands of residents and several new mixed-use developments, making it an ideal location to establish your business in one of San Diego’s most dynamic and walkable neighborhoods

Date on Market:

2025-12-18

San Diego Office, Office/Retail for Lease - Mission Gorge

Turnkey brewery space with equipment, outdoor patio, large windows, and restroom Turnkey retail features high ceilings, two roll up doors, restroom, and large open space Existing office space features five offices, two restrooms, and a kitchenette Lifestyle center with on-site management and pride of ownership High visibility on Friars Road, a main Mission Gorge thoroughfare - 9,686 ADT Adjacent to SDSU West Campus, a mixed-use transit oriented university campus Recently upzoned for high-density residential, with plans to add up to 8,750 housing units and 22,000 new residents to the neighborhood Ease of commute with central location, short distance to multiple freeways, and nearby transit options Close proximity to Fenton Market Place, Fashion Valley, and Kaiser Permanente Increasing development activity - just 7 minutes from Snapdragon Stadium Development Neighbors include Filippi’s Pizza Grotto, Corner Thai Kitchen, Better Buzz, San Diego Brewing Co., and more!

Date on Market:

2025-05-21

San Diego Office for Lease - Downtown

Office Space for Lease in East Village – 345 15th Street, San Diego, CA 92101 Discover a prime office opportunity in the heart of San Diego’s vibrant East Village. Located at 345 15th Street, this versatile office space offers ±2,500 to 5,000 SF available for lease at $2.00/SF + utilities. Ideal Location Situated just blocks from I-5 and Hwy 163, this office space offers excellent freeway access and walkability to premier local amenities. Enjoy proximity to: Petco Park Mission Brewery Fault Line Park Convention Center Popular cafes and eateries like Basic Pizza, Copa Vida Coffee, and The Mission Café

Date on Market:

2025-04-29

San Diego Flex for Lease - Rancho Bernardo

Three buildings consisting of +-65,550 SF, professionally managed, prime corner location off of Rancho Bernardo Rd

Date on Market:

2025-03-06

San Diego Office for Lease - Sorrento Mesa

Date on Market:

2024-04-01

San Diego Office for Lease - Sorrento Mesa

Spectacular modern architecture with abundant natural light and fantastic on site amenities.

Date on Market:

2022-10-24

San Diego Multiple Space Uses for Lease - Downtown

Date on Market:

2024-07-19

San Diego Office/Retail for Lease - Downtown

Second generation brewery site featuring inviting tasting room and space for events Renovated in 2016; updated structure and utilities, while retaining its charming and historic facade Located in Downtown’s largest neighborhood which is home to over 700 thriving businesses Located just one block north of Petco Park which generated 3.3 million Padre’s game attendees in 2024 Neighbors include Arcade Monsters, Bub’s at the Ballpark, Tom’s Watch Bar, Another Broken Yolk and more! Great freeway ingress/egress via Hwy 163, Hwy 94, and I-5

Property Type:

Office

Date on Market:

2025-04-11

San Diego Retail for Lease - Southeast San Diego

Barrio Logan is an up-and-coming neighborhood in San Diego that has a rich history and a vibrant culture. Located just a short drive from downtown San Diego and Petco Park, Barrio Logan is a diverse and thriving community that is becoming increasingly popular with young professionals, artists, and entrepreneurs. With its unique blend of Mexican-American heritage, industrial chic, and artistic flair, Barrio Logan is a destination that is definitely worth exploring. One of the most notable things about Barrio Logan is its thriving arts scene. The neighborhood is home to dozens of galleries, studios, and performance spaces, where local artists showcase their work and share their passion for creativity with visitors. From the iconic murals that adorn the sides of buildings to the eclectic street art that lines the streets, Barrio Logan is a place where art and culture are celebrated and embraced. Another thing that makes Barrio Logan such a special place is its strong sense of community. Despite being located just a short drive from downtown San Diego, Barrio Logan has managed to maintain its own unique identity and sense of place. Whether you’re exploring the neighborhood’s many art galleries and shops, sampling its delicious Mexican cuisine, or simply soaking up the vibrant atmosphere, there’s no denying that Barrio Logan is a place that is full of life and energy.

Date on Market:

2025-10-27

San Diego Retail for Lease - Uptown East

Date on Market:

2025-03-06