13 Breweries for Lease in San Diego, CA, USA

San Diego Office/Retail for Lease - Downtown

Rare small space in Little Italy, one of Downtown’s most desired neighborhoods Highly visible location and signage opportunity Space features a private office, restroom, hard wood flooring, and a long inviting entryway Immediate access to I-5 and blocks from numerous Little Italy Hot Spots Potential on-site and ample street parking Located in a rapidly developing area - over 5,000 units proposed and under construction Neighbors include Lala, Cloak & Petal, Bolt Brewery, Barbusa, Born & Raised & more!

Property Type:

Multifamily

Date on Market:

2026-02-10

San Diego Retail for Lease - Park East

Available for lease for the first time in over a decade, 4223 30th Street presents a rare opportunity to occupy one of North Park’s most recognizable commercial buildings. The property offers ±5,900 SF of interior space plus an additional ±1,600 SF fenced outdoor patio, ideal for dining, entertainment, or gathering space. The entire building is available for lease, with the option to lease individual suites ranging from ±1,600 SF to ±5,900 SF. Positioned at the highly visible intersection of 30th Street and El Cajon Boulevard, this landmark property features the renowned “Greetings from San Diego” mural, making it a well-known destination within one of San Diego’s most vibrant and walkable neighborhoods. The building is thoughtfully designed for hospitality and creative concepts, featuring glass-panel roll-up doors, exposed wood ceilings, two built-out bar areas, four restrooms, and impressive 20-foot warehouse ceilings. Additional infrastructure includes 600-amp, 3-phase power and gas service, making it ideal for restaurant, brewery, distillery, café, retail, or experiential concepts. Previously home to a brewery tasting room and coffee roastery, the property benefits from a proven hospitality layout and strong local recognition. Surrounded by thousands of residents, new mixed-use developments, and established retail and dining destinations, the location offers exceptional visibility, accessibility, and foot traffic. With its iconic identity, flexible layout, and prime North Park location, 4223 30th Street provides a unique opportunity for a flagship concept looking to establish or expand in one of San Diego’s most sought-after commercial districts. Take a Virtual Tour by clicking this link: https://my.matterport.com/show/?m=nit1nfUN6pj

Date on Market:

2025-12-18

San Diego Office/Retail for Lease - Mission Gorge

Turnkey brewery space with equipment, outdoor patio, large windows, and restroom Turnkey retail features high ceilings, two roll up doors, restroom, and large open space Existing office space features five offices, two restrooms, and a kitchenette Lifestyle center with on-site management and pride of ownership High visibility on Friars Road, a main Mission Gorge thoroughfare - 9,686 ADT Adjacent to SDSU West Campus, a mixed-use transit oriented university campus Recently upzoned for high-density residential, with plans to add up to 8,750 housing units and 22,000 new residents to the neighborhood Ease of commute with central location, short distance to multiple freeways, and nearby transit options Close proximity to Fenton Market Place, Fashion Valley, and Kaiser Permanente Increasing development activity - just 7 minutes from Snapdragon Stadium Development Neighbors include Filippi’s Pizza Grotto, Corner Thai Kitchen, Better Buzz, San Diego Brewing Co., and more!

Date on Market:

2025-05-21

San Diego Office for Lease - Downtown

Office Space for Lease in East Village – 345 15th Street, San Diego, CA 92101 Discover a prime office opportunity in the heart of San Diego’s vibrant East Village. Located at 345 15th Street, this versatile office space offers ±2,500 to 5,000 SF available for lease at $2.00/SF + utilities. Ideal Location Situated just blocks from I-5 and Hwy 163, this office space offers excellent freeway access and walkability to premier local amenities. Enjoy proximity to: Petco Park Mission Brewery Fault Line Park Convention Center Popular cafes and eateries like Basic Pizza, Copa Vida Coffee, and The Mission Café

Date on Market:

2025-04-29

San Diego Flex for Lease - Rancho Bernardo

Three buildings consisting of +-65,550 SF, professionally managed, prime corner location off of Rancho Bernardo Rd

Date on Market:

2026-04-02

San Diego Office for Lease - Sorrento Mesa

Date on Market:

2024-04-01

San Diego Office for Lease - Sorrento Mesa

Spectacular modern architecture with abundant natural light and fantastic on site amenities.

Date on Market:

2022-10-24

San Diego Multiple Space Uses for Lease - Downtown

Date on Market:

2024-07-19

San Diego Industrial for Lease - Scripps Ranch

Date on Market:

2026-04-02

Chula Vista Office, Retail for Lease

Street Front Retail on 3rd Avenue Located on the west side of Chula Vista, the Third Avenue Village is a historical architectural district that features a newly renovated and picturesque business area, an emerging cultural arts and craft brew scene, and a unique collection of boutiques, eateries and services.

Date on Market:

2026-02-13

San Diego Retail for Lease - Park East

The Intersection of 30th & University is widely known as the heart of North Park, serving as the epicenter of the neighborhoods energy and foot traffic. A high growth neighborhood attracting local and national retailers alike as well as live entertainment from around the world at The Observatory. This particular block is undergoing a significant revitalization via new 4 new projects by Consortium Holdings, Empress Family of Restaurants, Bivouac Ciderworks and Saigon Coffee all currently under construction.

Date on Market:

2025-11-21

San Diego Office/Retail for Lease - Southeast San Diego

Barrio Logan is an up-and-coming neighborhood in San Diego that has a rich history and a vibrant culture. Located just a short drive from downtown San Diego and Petco Park, Barrio Logan is a diverse and thriving community that is becoming increasingly popular with young professionals, artists, and entrepreneurs. With its unique blend of Mexican-American heritage, industrial chic, and artistic flair, Barrio Logan is a destination that is definitely worth exploring. One of the most notable things about Barrio Logan is its thriving arts scene. The neighborhood is home to dozens of galleries, studios, and performance spaces, where local artists showcase their work and share their passion for creativity with visitors. From the iconic murals that adorn the sides of buildings to the eclectic street art that lines the streets, Barrio Logan is a place where art and culture are celebrated and embraced. Another thing that makes Barrio Logan such a special place is its strong sense of community. Despite being located just a short drive from downtown San Diego, Barrio Logan has managed to maintain its own unique identity and sense of place. Whether you’re exploring the neighborhood’s many art galleries and shops, sampling its delicious Mexican cuisine, or simply soaking up the vibrant atmosphere, there’s no denying that Barrio Logan is a place that is full of life and energy.

Date on Market:

2026-04-06

San Diego Retail for Lease - Uptown East

Date on Market:

2025-03-06