27 Convenience Stores for Lease in St. Louis County, USA

University City Office for Lease - Creve Coeur/Hwy-67

Louis London Annex on Delmar Boulevard presents a strategically positioned ground-floor retail opportunity, ideal for a café, salon, or cell phone store. With thoughtful build-out modifications, the space can also accommodate a variety of retail concepts, including yoga or Pilates studios. Above, the mixed-use building offers premium office space featuring a mix of open work areas and private perimeter offices, providing a dynamic environment for businesses of all sizes. Flexible floor plans cater to various needs, making this an exceptional opportunity for companies seeking a prestigious and adaptable setting in a prime location. Louis London Annex is situated on University City's main artery, Delmar Boulevard, frequented by approximately 20,000 vehicles daily. In the heart of the Delmar Loop district, this property is walkable to a wide array of boutique shopping, hip restaurants, and entertainment. The Loop Trolley stop is conveniently in front of the building for the 2-mile streetcar line from St. Louis to University City. Set up space at Louis London Annex, where businesses, from wellness studios and salons to tech retailers and more, can benefit from exceptional visibility and a sought-after St. Louis suburb.

Date on Market:

2025-02-04

Hazelwood Office for Lease - Airport

Located in the highly active and business-friendly area of Hazelwood, Missouri, and adjacent to the St. Louis International Airport, the professional office property at 945-951 Hornet Drive offers an exceptional environment for companies seeking visibility, convenience, and a strong sense of community. Situated directly across from the Boeing campus, tenants will enjoy being part of a thriving corporate neighborhood. The property provides ample on-site parking, a high standard of professionalism, and a strong sense of safety, making it ideal for businesses that prioritize both functionality and prestige. The available move-in ready spaces include flexible space options ranging from 1.200 up to 3,500 square feet, ideal for growing teams as well as institutional tenants. Just minutes from St. Louis Lambert International Airport, the location offers seamless access to major transportation routes, with Interstate 270 directly adjacent, and both Interstate 70 and Interstate 170 only minutes away. This well-connected location sits just 3.9 miles from SSM Health DePaul Hospital, offering added strength for medical tenants. The area is also an established commercial hub, providing employees with easy access to exceptional conveniences, including retail, restaurants, and service-based amenities. 945-951 Hornet Drive poses an excellent opportunity for companies looking to establish or expand their presence in one of the most accessible and well-regarded business corridors in the St. Louis metro area.

Date on Market:

2025-05-14

Saint Louis Office for Lease - I-270/Maryland Heights

92,640 SF Class B office building with multiple suites available for lease. Amenities include signage opportunities on Page Avenue, Prime Westport location with Westport Plaza amenities within walking distance, and aggressive tenant improvement allowance. The building is located in the city of Maryland Heights, located just east of I-270 and south of Page Avenue in the Olive-270/Westport submarket. The Olive-270/Westport submarket contains a total of 7.5 million square feet of office space. Its close location to Westport Plaza accommodates numerous support services, restaurants and hotels. The location provides excellent access to interstates, St. Louis-Lambert International Airport and into St. Charles and St. Charles County.

Date on Market:

2026-02-02

Maryland Heights Office for Lease - Earth City/Riverport

Located in the heart of the Riverport business park, Riverport Lakes places tenants in one of the region’s most active commercial hubs. The building benefits from fast access to the area’s primary highways and is surrounded by established employers and hospitality amenities. The immediate area offers a professional setting that supports daily operations and client engagement. Its Riverport location enhances both convenience and operational efficiency, from both St. Charles and St. Louis County.

Date on Market:

2026-03-10

Maryland Heights Office for Lease - Earth City/Riverport

Located in the heart of the Riverport business park, Riverport Lakes places tenants in one of the region’s most active commercial hubs. The building benefits from fast access to the area’s primary highways and is surrounded by established employers and hospitality amenities. The immediate area offers a professional setting that supports daily operations and client engagement. Its Riverport location enhances both convenience and operational efficiency, from both St. Charles and St. Louis County.

Date on Market:

2026-03-10

Saint Louis Retail for Lease - I-270/Olive Blvd

Date on Market:

2025-10-16

Fenton Office for Lease

Positioned just off Interstate 44 and only two miles from the I-44/I-270 interchange, the property offers unmatched regional access to major transportation routes, reducing transit times and improving distribution efficiency. Nearby amenities include popular dining and service options such as Wally’s Fenton Bar and Grill, Cracker Barrel, and Bandana’s BBQ, providing convenience for staff and clients alike. This property combines functionality, accessibility, and value in one of St. Louis’ most desirable industrial corridors.

Property Type:

Industrial

Date on Market:

2026-01-13

Chesterfield Office for Lease - Chesterfield/Hwy-40

Date on Market:

2021-04-07

Bridgeton Office, Office/Retail for Lease - Bridgeton/I-70

Date on Market:

2026-02-09

Saint Louis Retail for Lease - South County

Commercial retail property for rent about 6000 sqft ,new heating and cooling system, everything is electric new gutters new roof, updated electric 3 face and 200 Amp. For more info please call 314-393-2911 AT Real Estate LLC.

Date on Market:

2025-05-04

Creve Coeur Office, Office/Retail for Lease - I-270/Olive Blvd

Fernwood Plaza offers a prime leasing opportunity in the heart of Creve Coeur along Olive Boulevard, one of St. Louis’ most traveled corridors with a traffic count of 33,170 vehicles per day. This vibrant center features a turn-key urgent care space on the first floor and multiple suites ranging from 750 to 5,250 SF, ideal for medical, wellness, or professional office users. The property boasts a newly remodeled storefront, elevator service, and ADA accessibility, ensuring a modern and convenient experience for tenants and visitors alike. Strategically positioned with signalized access and surrounded by strong demographics, Fernwood Plaza benefits from a population of over 55,000 within a three-mile radius. The location offers excellent visibility and connectivity to major thoroughfares, including I-270 and Highway 141, making it easily accessible for patients and clients. Nearby amenities include retail, dining, and residential communities, creating a dynamic environment for businesses seeking growth and exposure. Whether you’re expanding a healthcare practice or establishing a professional office, Fernwood Plaza delivers a high-traffic, high-visibility setting in one of St. Louis’ most desirable submarkets.

Date on Market:

2025-11-26

Richmond Heights Office/Medical, Medical for Lease - Clayton

Located on the campus of SSM St. Mary's Hospital. The campus offers many amenities including a physician's lounge, full service cafeteria, coffee kiosk, valet, pharmacy, gift shop, reserved physician parking, two MRI machines and a complementary mix of healthcare referral partners!

Date on Market:

2026-02-13

Clayton Office for Lease

Bemiston Tower located at 231 S Bemiston Ave in Clayton Missouri is a 4 star, 14 story office building with newly upgraded building common areas and amenities. The building boasts of a conference room and attached five-level garage with automated access system with bike friendly parking and storage. The tenant exclusive expanded fitness center is equipped with Peloton bikes, The Mirror tech, and on-site private personal training. There is new on-site café (Toast & Thyme), grab-n-go, and tenant lounge to recharge. Located in Saint Louis's premier office submarket and financial business center the property is very short walking distance from the Clayton Metrolink with easy access to Forest Park Parkway and Interstate 170.

Date on Market:

2025-10-06

Saint Louis Office/Retail, Retail for Lease - South County

1,235 – 2,720 SF retail space with ample parking and monument signage available. Good location next to St. Louis Community College with signalized access to Lemay Ferry.

Date on Market:

2018-02-05

Creve Coeur Office for Lease - I-270/Olive Blvd

The building features a welcoming tenant break room, ample free parking for staff and visitors, and prominent monument signage to elevate your brand visibility. High-speed connectivity is guaranteed with Charter and AT&T Fiber, supporting modern business operations with reliable bandwidth. Located on Craig Road, the property provides quick access to major thoroughfares, including I-270 and Olive Boulevard, placing you minutes from St. Louis’ central business district and Lambert International Airport. Creve Coeur is a thriving business hub known for its strong corporate presence, upscale amenities, and vibrant community. Nearby, you’ll find a mix of dining, retail, and professional services, creating a dynamic environment for employees and clients alike. Whether you need a small suite or a larger footprint, the 655 Building delivers flexibility, convenience, and a professional setting tailored to your success.

Date on Market:

2026-03-13

Saint Louis Office for Lease - I-270/Maryland Heights

Date on Market:

2025-04-14

Maryland Heights Industrial for Lease - Earth City/Riverport

Property Type:

Flex

Date on Market:

2023-09-15

Clayton Coworking for Lease

Office Evolution Clayton at 231 S Bemiston Avenue provides executive office space with highly desirable amenities in the Bemiston Tower. The property offers 13,885 square feet of shared workspace in the heart of Clayton's central business district, with a superior 8th-floor location giving sweeping views of the city. At Office Evolution Clayton, find workspaces built to inspire, from private offices for daily use to flexible coworking spaces for various users, all within a supportive community of professionals. Professional business address options are available as Office Evolution offers search-friendly mail plans. Excellent building amenities include a state-of-the-art fitness center, secured bike storage, and a modern on-site café. Meeting rooms and conference spaces allow for team collaboration and breakout space. Within walking distance are some of the city's best retail and restaurant options among brick-paved walkways and historic architecture. Commuting is a breeze with The Clayton Metro station just two blocks away, nearby roadways including the Interstate 170 corridor and adjacent Forest Park Parkway, and ample attached covered parking available. Clayton is a suburban yet sophisticated city outside Saint Louis, directly west of Forest Park and the Saint Louis Zoo, and borders the Washington University campus. Office Evolution Clayton is at the center of it with luxury hotels like Le Meridien and The Ritz-Carlton, and community green space like Shaw Park, filled with walking paths, tennis courts, fields, and premier outdoor swimming facilities, just a short walk away. Lambert-St. Louis International Airport and Downtown St. Louis are located 15 minutes away. Surrounding neighborhoods include Brentwood, Richmond Heights, Ladue, Maplewood, the CWE, Webster Groves, Kirkwood, and Glendale. When high-end work environments, connectivity, and convenience are key, Office Evolution Clayton is the ideal destination.

Property Type:

Office

Date on Market:

2022-12-15

Creve Coeur Office for Lease - I-270/Olive Blvd

Date on Market:

2025-06-17

Creve Coeur Coworking for Lease - I-270/Olive Blvd

Executive Office Availability within CityPlace CityPlace Center provides upscale, professional facilities with your business needs in mind. CityPlace, a recipient of regional Beautification Honors, offers sweeping views from the terrace overlooking a three-acre lake as well as a fitness trail which connects our clients to nature. CityPlace Center features a radiant atrium along with personal and professional amenities such as CityPlace Cafe and a fitness center. Furnished and equipped meeting rooms enhance the efficient, professional environment. Videoconferencing, LCD projectors and other advanced audio-visual technology is available for your next long distance meeting. Our on-site support team is happy to provide professional administrative support. Access to a 150-seat auditorium in the adjacent building is also available. Plentiful parking is located adjacent to the Center. CityPlace Center is just minutes away from luxurious hotels, superb dining, banking services and exciting entertainment. Hotels in close proximity include Courtyard, Drury Inn and Suites, Staybridge Suites, Residence Inn, Clubhouse Inn & Suites and Comfort Inn. A plethora of dining options are available for our distinguished clients. A short 15-minute drive will take you to downtown St. Louis, and Lambert St. Louis International Airport is accessible in just 10 minutes.

Property Type:

Office

Date on Market:

2002-05-20

Saint Louis Coworking for Lease - I-270/Maryland Heights

Landmark Business and Entertainment Destination Strategically Located at Page & I-270 Intersection Proximate to Key Labor Markets Direct Access into St. Charles County via MO 364 5-10 Minutes to Lambert Airport (Complimentary Shuttle) High Speed Internet and Fiber Availability Two Sheraton Hotels On-Site with 500+ Rooms Professional Conference Center in Complex On-Site Management

Property Type:

Office

Date on Market:

2006-09-13

Sunset Hills Office for Lease - South County

Position your business at 9735 Landmark Parkway, a premier office destination in Saint Louis offering unmatched convenience and modern upgrades. This property is undergoing new common area improvements, creating a refreshed and professional environment for tenants. With immediate access to Highway 270, your team and clients will enjoy seamless connectivity to the entire metro area, including major business hubs and residential communities. The building features large blocks of space, making it ideal for growing companies or those seeking flexible layouts for collaborative work environments. Fiber optic data connectivity ensures high-speed internet performance, supporting today’s technology-driven operations.

Date on Market:

2026-01-16

Eureka Flex for Lease - West County

Strategically located along W. 5th Street with prominent monument signage and direct visibility from Interstate 44, this site delivers exceptional branding opportunities and easy access for employees and clients. Traffic counts of over 68,000 vehicles per day on I-44 underscore the property’s exposure. Nearby amenities include national retailers, dining options, and essential services, creating a vibrant business environment. Eureka’s strong demographics—average household incomes exceeding $170,000 within a 5-mile radius—reflect a prosperous community ideal for growth.

Date on Market:

2025-11-24

Chesterfield Coworking for Lease - Chesterfield/Hwy-40

Property Type:

Office

Date on Market:

2026-03-11