30 LEED Certified Buildings for Lease in San Diego, CA, USA

San Diego Flex for Lease - Sorrento Mesa

Pacific Center is a new life sciences campus being developed in phases over four years in San Diego’s desirable Sorrento Mesa Submarket. Construction began in May 2023 and will be tenant improvement-ready in March 2024. The first phase will include 500,000 rentable square feet of state-of-the-art scientific research space, a 28,000-square-foot amenity center, and a 1,700-space parking facility. This landmark facility’s configuration is designed to accommodate tenants with varying industry needs and those searching for space that promotes the perfect work/life balance. Prominently located at the intersection of Mira Mesa Boulevard and Pacific Heights Boulevard, Pacific Center exemplifies the elegance of 21st-century contemporary architectural design. Each building boasts access to world-class amenities, including multiple outdoor roof decks and patios conducive to employee relaxation and team building. Tenants can also enjoy an on-site gym and fitness center operated by a third party, a chef-driven restaurant, a market hall, and various entertainment spaces spread throughout the campus. Each building’s interior includes large floor plate designs that can accommodate various life sciences uses. Tucked along the interchanges of the 5 and 805 Freeways and just under 10 minutes from UC San Diego, Sorrento Mesa has become the bastion of San Diego’s life sciences and tech scene. While the US Navy remains the largest employer in the city, life sciences and tech have exploded throughout the Sorrento Mesa Submarket. Notable businesses in the submarket include Qualcomm, Dexcom, NuVasive, Fujitsu, T-Mobile, and many more. As Southern California's life sciences and tech sectors continue to expand, so does Sorrento Mesa's growing demand.

Date on Market:

2023-05-31

San Diego Office, Retail for Lease - College Area

Completely Renovated – Move-In Ready Brand-new interior with upgraded finishes, modern lighting, new flooring, and fresh paint throughout. Prime Signalized Intersection Exposure Located at University & Swift Avenue with 34,225 daily passing vehicles. 12-Foot High Exposed Ceilings Stylish, airy interior ideal for boutique, studio, or showroom use. Glass Storefront with Direct Street Access Excellent visibility and natural light with steady foot traffic in a highly walkable area. High Walk Score Location Walk Score of 93 nearby — surrounded by popular cafes, local shops, and public transit. Close to I-805 On/Off Ramps Easy access for customers and delivery logistics. Flexible, Open Layout Adaptable to retail, creative office, wellness, or specialty use. Strong Demographics Over 61,000 daytime population within a 5-minute drive and average HHI over $110,000. Surrounded by National Brands Near Starbucks, CVS, Sprouts, Chevron, and more — increased exposure through synergy.

Date on Market:

2025-10-15

San Diego Office for Lease - Mira Mesa/Miramar

• ±11,910 SF freestanding two-story office building • Approximately 70,000 SF of fenced in contractor Yard • ±6,220-11,910 SF available • Fenced yard space • 400 amp power • Energy efficient solar: 35.19 kw on roof + additional 9kw on carport available to tenant • Carport has twin EV charger capability • ±35 on-site parking spaces • Highly-desirable Miramar location • Easy access to Interstate 805

Date on Market:

2024-08-16

San Diego Retail for Lease - Old Twn/S Arena/Pt Loma

PRIME SPORTS ARENA AREA LEASING OPPORTUNITY WITH EXCELLENT PARKING AND LED PYLON SIGNAGE AVAILABLE. PROPERTY HAS FRONTAGE ON JUPITER STREET AS WELL. EASY ACCESS TO INTERSTATE 8 AND 5 FREEWAYS, DOWNTOWN, PACIFIC BEACH, SEA WORLD AND POINT LOMA AREAS. STRONG REGIONAL TRADE AREA

Date on Market:

2025-10-15

La Mesa Office for Lease - East County

Date on Market:

2025-08-04

San Diego Office for Lease - Mission Valley

Cushman & Wakefield is pleased to offer for lease Rio San Diego Plaza II, located at 2275 Rio Bonito Way. Rio San Diego Plaza II is a 74,947 SF, 3-story class A office building in the heart of Mission Valley.

Date on Market:

2025-04-11

San Diego Office, Industrial for Lease - Otay Mesa

Date on Market:

2025-11-25

San Diego Office for Lease - Del Mar Hts/Carmel Valley

- 5/1000 USF parking ratio (highest ratio in Del Mar Heights) including executive subterranean parking - Shower & locker facilities on site - Secured after-hour building access - Exceptional Del Mar Heights location on High Bluff Drive - Building signage and monument signage opportunities - Exposure to over 250,000 cars per day on I-5 - Close proximity to exclusive residential communities of Del Mar, Rancho Santa Fe and Carmel Valley

Date on Market:

2025-03-20

San Diego Office for Lease - Sorrento Mesa

One Pacific Heights is a high-image class A office building. The project underwent recent renovations that include: new architectural enhancements at main project entrance, new outdoor seating area, first floor lobby renovations and a new shower / locker room facility. Located on the corner of Mira Mesa Boulevard and Pacific Heights Boulevard

Date on Market:

2025-10-27

San Diego Office for Lease - Sorrento Mesa

Sorrento Towers serves as the “gateway” to San Diego’s technology hub, Sorrento Mesa. Towers is made up of two Class A office buildings totaling 295,000 SF, located next to numerous fast casual and sit down dining options. This campus setting provides the ultimate environment for today’s most innovative companies. Sorrento Towers provides unparalleled amenities, which include: a cutting edge fitness center complete with shower and locker facilities, state-of-the art conference center, outdoor seating and gathering areas, covered parking and on-site management. The project is ideally situated on the western edge of Sorrento Mesa, which provides direct access to Interstate 805 and is in close proximity to the Amtrak station. Direct access to retail and food service amenities.

Date on Market:

2025-10-29

San Diego Office for Lease - Mission Valley

Hazard Center Office Tower is Mission Valley’s only true mixed-use office and retail destination. This Class A, 15-story tower offers 273,710 RSF of premium workspace and is LEED Gold, WELL, and Energy Star certified. Tenant’s and their employees will have direct access to The Landing at HZRD, which will bring a reimagined retail and entertainment experience with new dining, flexible event space, and curated community programming—cementing Hazard Center as Mission Valley’s premier Class A mixed-use office destination. The Landing at HZRD will be completed in 2026.

Date on Market:

2025-09-24

San Diego Retail for Lease - Downtown

Retail/Restaurant space for lease. Situated near a public parking lot with more than 50 parking spaces. Ideally located between the Broadway Corridor, with high daytime population and the East Village, with dense residential. Adjacent to 800 Broadway, a 400-unit residential tower currently under construction.

Property Type:

Multifamily

Date on Market:

2025-04-21

San Diego Retail for Lease - Downtown

Property Type:

Multifamily

Date on Market:

2024-06-14

San Diego Office for Lease - Sorrento Mesa

Seaview Corporate Center is a four-building campus environment with three high-rise, high-image Class A office buildings and one R&D facility. With its superior Northwestern location in Sorrento Mesa, Seaview allows excellent access to I-805 and I-5. Seaview Corporate Center features numerous amenities including a recently expanded and revitalized gym, tennis/basketball court and pool for employee use. The quality and location of the Seaview Corporate Center makes it the Premier Class A campus in San Diego. Located in Sorrento Mesa off of Telesis Court and Lusk Boulevard.

Date on Market:

2025-10-29

San Diego Office for Lease - Kearny Mesa

Located about nine miles north of Downtown San Diego, Kearny Mesa is a vibrant suburb brimming with exciting things to see and do. Residents delight in a slew of diverse eateries, shops, and markets situated throughout the neighborhood, most of which are concentrated in convenient shopping centers and plazas.

Date on Market:

2022-08-22

San Diego Flex for Lease - Sorrento Mesa

This building is located near top San Diego Life Science and Telecommunication companies and part of 5 BUILDING CAMPUS TOTALING APPROXIMATELY 315,000 SF. Includes a robust laboratory infrastructure, dock- high & grade level loading, property and building enhancements completed, prominent building top and monument signage opportunities.

Date on Market:

2018-03-15

San Diego Flex for Lease - Del Mar Hts/Carmel Valley

Pacific Plaza @ Torrey Hills offers excellent visibility and signage; showers, lockers and fitness facility on-site; state-of-the-art energy management system; computerized security, HVAC and lighting; integrated network for fiber optic cable telephone system, and over 50% of the parking is covered. Situated on a bluff offering panoramic views of the Pacific Ocean, Torrey Pines and Del Mar, Pacific Plaza @ Torrey Hills has unequaled freeway visibility with exposure to over 275,000 cars a day. It is located in the center of San Diego's fastest growing and most dynamic area, with proximity to hotels, restaurants and retail services with executive, moderately priced single and multi-family housing nearby.

Date on Market:

2025-02-10

San Diego Office for Lease - Downtown

Date on Market:

2025-08-08

San Diego Office for Lease - Mission Valley

A modern workspace for a modern workforce. As the former site of the San Diego Union-Tribune, AMP&RSAND is an iconic landmark pressed in San Diego’s history and reimagined for the demands of the modern workforce. The printing press was the first form of technology to spread ideas while creating a platform for a more connected world. When the Union-Tribune stopped its presses in 2016, it made one final impression — the ampersand. Historic at its core but progressively redesigned, AMP&RSAND transcends the traditional San Diego office space. New Bike storage at the project!

Date on Market:

2020-12-09

San Diego Flex for Lease - Mira Mesa/Miramar

Sorrento Ridge Research Park has been reinvented to form a dynamic environment, thoughtfully centered around creating a modern solution for life science users. The advantages provided by its strategic location, building efficiencies, canyon view, and outdoor connectivity will allow the end user to effectively advance research and discovery and promote innovation. • Spec lab improvements now complete! • 60,734 SF of spec lab & office • Divisible to 7,000 SF • House vacuum & compressed air • New 500kw generator • Shipping and receiving area with freight elevator • 3 loading areas, 2 grade level doors & 1 oversized double man door • 2 gas lines & 1 water line • Outdoor patio and amenity space with seating & BBQ • 2nd Floor private patio spaces • Central lobby with meeting & collaboration spaces • 3/1,000 parking ratio (expandable) & EV charging stations

Date on Market:

2019-07-15

San Diego Flex for Lease - Downtown

GENESIS - San Diego connects the region’s scientific community with the most modern and cutting-edge facilities designed to date with strategically engineered laboratories and highly designed office space. Over +/-200,000 RSF and eight-stories of Class A LEED Gold life sciences space, this project provides an environment for fundamental innovation and creation. Set amongst San Diego’s thriving downtown core, GENESIS - San Diego offers vibrant experiences at its doorstep – whether it’s the perfectly curated California-Mediterranean palette at Callie restaurant, the trolley station just steps from the front door or a baseball game at Petco Park. PREMIER LAB SPACE IN DOWNTOWN SAN DIEGO | Move In TODAY!

Property Type:

Office

Date on Market:

2021-03-12

San Diego Coworking for Lease - Downtown

ITS TIME TO CREATE AT SPACES MAKERS QUARTER IN SAN DIEGO. East Village, San Diego, has become a nexus of redevelopment in SoCal, with the new-build Makers Quarter at its heart. The buildings across this mixed-use campus are home to commercial and residential setups with a huge choice of restaurants, bars, bakeries, cafes, breweries, shops, galleries and boutiques surrounding a central core of modern and inspiring glass and steel buildings. Spaces Makers Quarter typifies the kind of amazing working environment that professionals have flocked to the area to find. Its offices, co-working lounges and conference rooms provide a flexible solution for businesses and entrepreneurs. Find inspiring workspaces at Spaces Makers Quarter: • Dream Office: Enjoy the perks of a private office with customizable workspaces for any team, flexible contracts that flow with your business, and 24/7 access so you can work on your time. • Join the Club: Unlock thousands of coworking spaces throughout the globe and tap into creative environments with a thriving business community of like-minded professionals. • Lock-In: Get the best of both worlds with the perks of a coworking membership and the privacy of your own office, including 24/7 access, a personal locker, and reservable meeting spaces. • Collaborate: Book one of the countless meeting rooms, open to members and non-members, designed to keep your team or clients comfortable, creative, and focused. • Virtual Office: Get a prestigious professional address with mail handling, phone answering services, access to networking events, and access to Spaces’ global network of business lounges. Just so you know; all images shown in this listing are from Spaces locations, but they may not correspond to this specific one.

Property Type:

Office

Date on Market:

2023-05-12

San Diego Office for Lease - Downtown

As our shared environments continue to evolve, Kilroy is actively ensuring the safety of our tenants and surrounding communities, going above and beyond to create functional and healthy spaces. At 2100 Kettner, some of these operational and design initiatives include: Activated open stairwell to reduce elevator congestion Outdoor terraces and roof deck create opportunities to collaborate Touchless elevator system, restroom features, and touchless door hardware in high traffic area Flexible floor plates allow for open and collaborative layouts Indoor/outdoor lobby reduces opportunities for congestion Low iron glass used throughout the project provides higher transparency while maintaining energy efficiency Localized HEPA filtration in main lobby, locker rooms, restrooms, mail room, and bike lockers, plus air purification in elevator cabs Above industry-standard outside air system, with outside air passing through Needle Point Bi-Polar ionization

Date on Market:

2018-07-17

San Diego Retail for Lease - Downtown

Embrace both work and leisure, the grand and the minutia, the history and the innovation at 2100 Kettner - the newest block in San Diego’s coolest, energetic, urban village.

Property Type:

Office

Date on Market:

2018-07-13