4 Life Science Properties for Lease in Burlingame, CA, USA

• Matterport 3D Tour

SOUTHLINE - 50 Tanforan Ave

South San Francisco, CA 94080

• Life Science
• Flex for Lease
• 48,685 - 717,743 SF
• 2 Spaces Available Now

South San Francisco Flex for Lease

Southline is an innovative, 31-acre purpose-built science and technology development in South San Francisco, conveniently located directly adjacent to BART and within walking distance to Caltrain. The campus will feature 2.8 million square feet of Class A office and life science space, offering an authentic work-life experience in one of the most exciting developing neighborhoods in the Bay Area. With modern innovation in mind, Southline offers expansive, flexible floor plates ranging from 50,000 to 100,000 square feet of office space. Up to 65,000 square feet is dedicated to life science use. Office ceiling heights of 16 feet on the ground floor and 14 feet on the upper levels provide a spacious, open feel. Life science areas feature 16 to 18 feet of clearance, accommodating high-capacity storage and specialized equipment. Generous 30- to 33-foot column spacing, a strong live load capacity of approximately 125 pounds per square foot, and 8,000 MIPs ensure the project is equipped to support even the most demanding operations. Designed for innovation, inside out, Southline has curated amenities, restaurants, and retail that give big ideas space to grow, offering structure for deep thinking and space for spontaneity. The mass timber dedicated amenity building brings to the campus a fitness and wellness center, a coffee bar and grab-n-go food options, a conference center, outdoor seating areas, a well-appointed walking trail, a fruit and veggie garden, a campus Caltrain shuttle, a designated rideshare area, and a bike barn with a repair desk. A beer garden, fire pits, food truck court, outdoor collaboration areas, games and activities, and the Southline Commons (a 2-acre open space) are included in Phase 2, coming soon. Situated at the intersection of 101, 380, and 280, where BART and Caltrain converge and just minutes from San Francisco International Airport (SFO), the entire Bay Area is as accessible as it has ever been at Southline. Over 2,300 housing units are within a short walk of this project. All this and more provides the opportunity to recruit and retain from everywhere. Southline is in the center of Lindenville, a burgeoning, mixed-use neighborhood that soon will become an employment hub and the cultural heart of South San Francisco. In addition, it is across the street from a planned new 400,000 square foot retail village at Tanforan, including restaurants, cafes, Target, and a cinema. This growing area will offer a walkable live/work community, creating opportunities to shape South San Francisco's next chapter. South San Francisco has a rich history of pioneering industry and seamlessly bridges the innovative spirit of San Francisco with the technological prowess of Silicon Valley. At Southline, inspiration is tradition, and the Industrial City will give birth to the next phase of creative thinkers, disruptors, and pioneers fueled by the energy of its surroundings.

Contact:

Newmark

Date on Market:

2024-07-17

Hide

See More

ReadySpaces South San Francisco (Harris) - 233 E Harris Ave

South San Francisco, CA 94080

• Life Science
• Industrial for Lease
• $48.92 CAD SF/YR
• 5,000 SF
• 1 Space Available Soon

• Air Conditioning
• Security System
• 24 Hour Access
• Conferencing Facility

South San Francisco Industrial for Lease

Experience logistics simplified at our South San Francisco Harris location. This flexible warehouse space features all the amenities your business needs to thrive, with units ranging from small to large configurations to accommodate businesses of all sizes. Strategically positioned with easy access to major transportation networks including I-101, I-280, and I-380, this location is just 5 minutes from San Francisco International Airport (SFO) and offers excellent proximity to Caltrain. Security and convenience come standard with 24/7 facility access, private secure units, well-lit pathways, building access control, video surveillance, and comprehensive visitor management systems.

Contact:

ReadySpaces

Date on Market:

2021-03-11

Hide

See More

250 S Maple Ave

South San Francisco, CA 94080

• Life Science
• Industrial for Lease
• $28.00 CAD SF/YR
• 2,503 SF
• 1 Space Available Now

South San Francisco Industrial for Lease

Positioned in the heart of South San Francisco’s thriving industrial corridor, 250 S Maple Avenue offers a rare opportunity to lease high-functioning office and warehouse units tailored for logistics and light manufacturing uses. The property features multiple suites ranging from 2,485 to 2,970 square feet, with options to combine for larger footprints. Each unit is equipped with 18-foot clear heights, drive-in doors, and dedicated parking, ensuring operational efficiency and ease of access. 250 S Maple Avenue is strategically located near major thoroughfares, including Highway 101 and Interstates 280 and 380, and offers direct access to San Francisco International Airport. Additionally, the property is within walking distance of the San Bruno BART Station. This site is just minutes from regional retail hubs like The Shops at Tanforan and San Bruno Towne Center. The property’s positioning on South Maple Avenue enhances visibility and accessibility, while tenant improvement allowances provide flexibility for customization.

Contact:

CBRE, Inc.

Date on Market:

2025-11-13

Hide

See More

19 Davis Dr

Belmont, CA 94002

• Life Science
• Office for Lease
• $53.53 CAD SF/YR
• 24,000 SF

• Private Restrooms
• Balcony

Belmont Office for Lease - Belmont/San Carlos

The property sits on a hilltop site with scenic views of the Bay Area and provides monument signage for strong visibility. Outdoor amenities include a large patio space, while interior features include two restrooms, two showers, and multiple storage areas. With abundant parking at a ratio of 3.5/1,000 and proximity to major highways—just two minutes from Highways 280 and 92 and five minutes from Highway 101—this location ensures excellent regional connectivity. The building is equipped with 800 amps, 208 volts, 3-phase power, supporting advanced operational needs.

Contact:

Newmark

Date on Market:

2026-03-26

Hide

See More

384 Foster City Blvd

Foster City, CA 94404

• Life Science
• Flex for Lease
• $68.62 CAD SF/YR
• 15,660 - 31,320 SF
• 1 Space Available Now

• Bio-Tech/ Lab Space
• Security System

Foster City Flex for Lease - Foster City/Redwood Shrs

Flexible Term Length 1-5 years • Freestanding 31,320 SF building • Plug & Play Office and Lab setup • 24 BSC hoods, 4 chemical fume hoods • Most of the Lab equipment is staying in place (full list upon request) • Central lab air, vacuum, purified water • CO2, N2, O2, He gas lines piped from yard • Single-pass lab HVAC • Cold room & glasswash rooms (Steris washer/dryer) • 1,600 amps, 277/480V power • 2 backup generators (150kW each, both voltages) • 1 grade-level loading door • Security with card access control • 3.3/1000 parking ratio • Low NNN: ~$0.30/SF

Contact:

Innovation Properties Group, Inc.

Date on Market:

2025-06-25

Hide

See More

999 Baker Way

San Mateo, CA 94404

• Life Science
• Flex for Lease
• $74.11 CAD SF/YR
• 100 - 30,288 SF
• 1 Space Available Now

• Bio-Tech/ Lab Space
• Reception

San Mateo Office, Flex for Lease

68,706 Square feet of lab and office space. Located in a highly sought-after, highly visible San Mateo location. The flex, lab and office building is owned by Rubicon Point Partners. The building was fully renovated with the 4th floor accommodating for co-working tenants and private labs. The tenants have access to an outdoor meeting and lounge area.

Contact:

Kidder Mathews

Date on Market:

2025-05-21

Hide

See More

407 Cabot Rd

South San Francisco, CA 94080

• Life Science
• Flex for Lease
• 1,000 - 17,000 SF
• 1 Space Available Now

• Bio-Tech/ Lab Space

South San Francisco Flex for Lease

±17,000 SF 2-story building with ±30,492 SF lot and ±49 parking spaces.

Contact:

Kidder Mathews

Date on Market:

2026-04-16

Hide

See More

East Grand Avenue - 249 E Grand Ave

South San Francisco, CA 94080

• Life Science
• Flex for Lease
• 8,266 - 30,516 SF
• 2 Spaces Available Now

South San Francisco Flex for Lease

Join a premier life science campus with the versatile spec suites available for lease at East Grand Avenue in South San Francisco, California. Coming available in September of 2026, these modern spaces include options for 22,250 and 37,532 square feet, offering an ideal canvas for growing teams and institutional businesses. This incredible business destination offers a range of exceptional on-site amenities that form an idyllic and energizing hub for corporate activity. Tenants enjoy access to an activated wellness center, a restaurant, sports courts, and a 300-person conferencing center. There is also abundant on-site parking available with EV charging stations, as well as generous outdoor space with outdoor walking trails and lush landscaping. Situated in a prominent location close to the Highway 101 interchange, this rare offer places businesses in an easily accessible commercial hub. The campus is just a short walk to the SSF Caltrain station, and less than 10 minutes from SFO airport. The surrounding area presents a wide array of desirable urban amenities, including top-rated shopping, dining, recreation, and hotels.

Contact:

JLL

Date on Market:

2026-05-12

Hide

See More