40 Life Science Properties for Lease in Colorado, USA

Denver Office/Medical, Medical for Lease - East I-70/Montbello

The Green Valley Ranch Medical Office Building at 4809 Argonne Street in Denver, Colorado, offers healthcare providers a premier opportunity to lease medical office space within one of Denver’s fastest-growing communities. Located approximately 17 miles east of Downtown Denver, this two-story, 45,767-square-foot medical office building features a strong tenant mix that includes primary care, urgent care, dental, vision, laboratory services, and an on-site pharmacy, creating a built-in referral network that supports patient retention and practice growth. Recently renovated common areas enhance the professional environment and patient experience, while ownership and management by Lillibridge Healthcare Services ensure high standards of building operations, responsiveness, and long-term stability. The first-floor space availability includes a move-in-ready, fully built-out spec suite. Green Valley Ranch Medical Office Building offers convenient patient access, covered patient drop off, ample on-site parking, and 24/7 on-call maintenance to support uninterrupted operations. The flexible leasing structure includes competitive rental rates and tenant improvement allowances to accommodate a wide range of medical build-outs, including clinical, outpatient, and specialty care uses. Biotech and lab space further expand the potential for advanced healthcare tenants. Green Valley Ranch Medical Office Building is strategically positioned at a signalized intersection, providing seamless ingress and egress. The building benefits from excellent regional connectivity, with direct access to Interstates 70, 225, and Highway 470, and is found just minutes from Denver International Airport. Bus line access makes the property easily accessible for both patients and staff. The surrounding area is anchored by new retail amenities and the award-winning Green Valley Ranch Golf Club, reinforcing the building’s role as a preferred healthcare destination for residents. With its prime location, established healthcare presence, and professionally managed environment, Green Valley Ranch Medical Office Building presents an exceptional opportunity for medical providers seeking to grow their practice in a thriving Denver healthcare corridor.

Date on Market:

2025-08-14

Greenwood Village Office/Medical for Lease

5800 S Quebec Street is adjacent to the Denver Tech Center, a primary professional hub known for its major companies that largely specialize in technology and the medical industries. As a result, well-educated households are proliferating in the area, and 64% of residents within a 3-mile radius have attained a bachelor's degree or higher. This advantageous address provides quick access via Interstate 25, allowing drivers to reach Downtown Denver, DIA, Boulder, Lakewood, and more in 20 to 40 minutes. Public transit users can walk to a light rail stop, and the immediate area is replete with lifestyle amenities. The Landmark, Target, REI, Sprouts Farmers Market, Fiddlers Green Amphitheater, multiple fitness options, over a dozen hotels, 100+ restaurants, and much more are all within 2 miles of the site.

Property Type:

Office

Date on Market:

2025-04-02

Denver Office for Lease - Colorado Blvd/I-25

Welcome to 2145 S Clermont Street in Denver's University Hills. This inviting, premier two-story office building offers turnkey flexible leasing options designed to accommodate growing businesses, making it easy for tenants to find the right-sized space for today's use and tomorrow's growth. Offered at $16 per square foot (inclusive), the building can be leased by the floor( 2,300 square feet), or a tenant has the option to lease the entire 4,660-square-foot building. The various sizing options are a great fit for small businesses, startups, or companies expanding into a location that can scale with them as they grow. 2145 S Clermont Street offers a prime location with direct access to Interstate 25 and a convenient, central Denver setting. Situated near the University of Denver and within walking distance of the Colorado Boulevard Light Rail Station, tenants enjoy seamless connectivity to Downtown Denver. This property offers a practical, welcoming workplace for modern office users who want flexibility, convenience, visibility, and a professional space, which was renovated in 2025.

Date on Market:

2026-02-04

Louisville Flex, Industrial for Lease - Boulder County

Date on Market:

2026-05-07

Littleton Office/Medical for Lease - Southwest Denver

SouthPark Medical Center is a premier medical office building situated within The Ridge at SouthPark in Littleton, Colorado. This expansive 50-acre development offers striking views of the Rocky Mountains, the High Line Canal, and McLellan Reservoir, creating an appealing environment for both patients and professionals. The Ridge at SouthPark is designed as a dynamic mixed-use community, blending commercial, office, retail, and dining options. It serves as a hub for professional healthcare providers and high-end corporate tenants, fostering a collaborative and prestigious business district. Featuring distinctive exterior architecture, the property provides tenants with strong visibility and an opportunity to establish a unique and recognizable presence in one of Littleton’s most desirable commercial areas.

Property Type:

Office

Date on Market:

2026-04-02

Louisville Flex for Lease - Boulder County

Kinsey & Company Commercial Real Estate is pleased to present The Collective I, a premier Class A office/flex opportunity located at 199 S. Taylor Street in Louisville. Completed in 2020, this modern multi-tenant asset totals 37,231 square feet, including mezzanine space, and sits on a 3.17-acre site within one of Boulder County’s most desirable and supply-constrained submarkets. The property is offered for sale or for lease, providing exceptional flexibility for owner-users, investors, and tenants. The Collective I accommodates a wide range of business strategies through three distinct acquisition and occupancy paths: (i) tenants may lease individual suites or multiple contiguous spaces, (ii) users may purchase an office/flex condominium to own and occupy their space, or (iii) buyers may acquire the entire building, occupy available suites, and continue leasing to the existing professional tenant base. Available spaces range from 3,780 to 26,084 square feet, allowing the property to serve both small and expanding organizations. Designed to a high standard, the building features clear heights of 20’–24’, 12’ x 12’ rear overhead glass doors, polished concrete floors (with upgrade options), and storefront glass glazing with custom signage mounts. Select suites offer turn-key clinical research lab space, while others are delivered as office spec-suites, providing immediate occupancy solutions. Each unit is individually metered for gas and electric, includes separate HVAC systems, and is internet-ready, offering operational efficiency and control for occupants. An abundant 4.1 per 1,000 SF parking ratio, accessible rear loading, and optional security and camera prewire surveillance further enhance functionality. Landscape maintenance is professionally managed by the HOA. Strategically located, The Collective I offers exceptional regional connectivity with immediate access to I-25, providing a direct commute to downtown Denver, and convenient access to Highway 36, connecting to downtown Boulder. The property also benefits from close proximity to Downtown Louisville, offering nearby dining, retail, and lifestyle amenities that appeal to employees and clients alike. The building is anchored by a strong roster of professional co-tenancy, including Peak Retirement Planners, Pigler Automation and Tandem Certified Public Accountants, creating a stable and synergistic business environment. With its modern construction, flexible ownership and leasing options, and premier Boulder County location, The Collective I represents a compelling opportunity for users and investors seeking long-term value in a high-demand market.

Date on Market:

2026-01-27

Englewood Office/Medical for Lease - Inverness

Suite 120 at 195 Inverness Dr W offers 1,668 SF of existing medical lab space with excellent potential for conversion to a primary care or concierge medical practice. Located in the heart of the Inverness / DTC submarket, the suite benefits from ground-floor access, a rare covered building drop-off, abundant parking, and immediate access to I-25 and E-470. Surrounded by corporate campuses, hotels, and executive housing, this is an ideal setting for boutique healthcare providers seeking a professional image and strong patient convenience.

Property Type:

Office

Date on Market:

2026-01-20

Louisville Flex for Lease - Boulder County

101 S. Taylor Avenue presents a rare and exceptional opportunity to acquire or lease a high-quality, meticulously maintained 56,054-square-foot commercial property in one of Boulder County’s most sought-after and dynamic business corridors. Situated within the prestigious Colorado Technology Center, the property provides outstanding access to Highway 36, Northwest Parkway, and the broader Denver/Boulder metro area. This prime location is ideal for a variety of users, including office, research and development, light industrial, or flexible space operations. The building boasts versatile floor plans, thoughtfully designed layouts, and abundant on-site parking, making it highly adaptable for both single-tenant and multi-tenant configurations. Businesses benefit from Louisville’s strong pro-business climate, a deep and skilled labor pool, and proximity to major technology employers. In addition, the surrounding area is rich in lifestyle amenities, including scenic trails, top-rated restaurants, and popular craft breweries. Strategically positioned in a supply-constrained submarket, 101 S. Taylor Avenue is exceptionally well-located for long- term value, growth, and stability.

Property Type:

Industrial

Date on Market:

2026-01-08

Watkins Coworking for Lease - Outlying Arapahoe County

Property Type:

Office

Date on Market:

2025-11-10

Greenwood Village Office for Lease

6080 Greenwood Plaza Blvd is an 8,771-square-foot office and lab building located in the heart of Greenwood Village. The property features well-finished office space with a dedicated 553-square-foot lab and clean room. Built in 1979 and zoned PUD within The Commons, the building offers flexible suite configurations and quality improvements suitable for a variety of professional, medical, or technical uses. The location provides excellent access to I-25, public transportation, and surrounding retail and dining amenities.

Date on Market:

2025-10-28

Fort Collins Office for Lease - Fort Collins/Loveland

Innosphere is the dynamic 3 Story LEED Platinum Innovation Center. Currently available are 3 Class A Office units available for lease. Ranging from 390 +/- square feet to 550+ square feet these are ideal as its more than just an exceptional space, it immerses you in a thriving entrepreneurial ecosystem. Innosphere offers state of the art facilities and amenities and a vibrant community just steps from Old Town. Offering free business educational programs, pushing the boundaries of bio-tech, research and more. Located on the north end of Old Town in Fort Collins, this building is within walking distance of New Belgium Brewing and provides easy access to Poudre River bike trail system. These suites offer access to reserve, free of charge, large and small meeting spaces with all A/V equipment. Enjoy a quick break or meeting on the large outdoor plaza and patio areas. Bike Storage, Ample parking, Bathroom Showers and lockers and did we mention the Espresso Machines free of charge? Call to visit this exciting opportunity today!

Date on Market:

2026-06-17

Colorado Springs Industrial for Lease - North

This centrally located, highly functional industrial facility has up to 59,452 SF of office, lab, manufacturing and warehousing space available for lease. Heavy 480v power distributed throughout, large parking and truck courtyard space offers outside storage potential. Over 11,000 SF of office/lab space on two floors. Easy all points access via Mountview or Fillmore to Nevada with close proximity to 1- 25 interchanges at Fillmore Street and North Nevada/Rockrimmon/Corporate Dr.

Date on Market:

2025-08-29

Louisville Industrial for Lease - Boulder County

Date on Market:

2025-03-20

Centennial Office, Office/Medical for Lease - Arapahoe Rd

Date on Market:

2026-06-04

Lafayette Office, Flex for Lease - Boulder County

This is an ideal Flex space for multiple uses. Great Private offices, an open Bullpen, potential warehouse space. Lease Rate: $15.95/SF NNN NNN Expenses: $10.00/SF Building Size: 20,313 SF Available SF: 5,622 SF Parking: 2.5/1,000 SF Year Built: 2001 Zoning: M-1 (Lafayette)

Date on Market:

2025-12-22

Denver Office for Lease - CBD

Welcome to The 410, a modern office in Denver’s Skyline District, designed to take care of tenants’ well-being, supporting them to perform at their peak. This building offers a plethora of amenities, including a modern coffee and wine bar, indoor and outdoor meeting spaces, outdoor lounge, conference spaces, and a state-of-the-art fitness center. Above the renovated lobby, the building’s 24 rectangular floors are spacious and energizing, with discreet columns and inspiring views across Denver’s Front Range. Ample retail amenities surround the property, including lodging, shopping, dining, and nightlife. Culture, creativity, design, innovation, and nature are all hallmarks of the new Upper Downtown. Plus, commuting is a breeze, with ample parking available on-site. W. Colfax avenue/I-70 is just a few blocks from the property, providing easy access to I-25. Alternatively, the area is adjacent to the 16th Street Free Mall Ride and adjacent to Light Rail stops. For business travelers, the Denver International airport is a 30-minute drive.

Date on Market:

2025-02-04

Loveland Flex for Lease - Outlying Larimer County

3800 N. Wilson Avenue presents a remarkable and rare opportunity for high tech manufacturing and life science users within Loveland, Colorado. This 221,000+ square foot campus sits on approximately 38.467 acres, offering ample space for production and research, as well as potential future expansion. Located in Loveland, in between Colorado State University and CU Boulder, this facility offers easy access to a skilled workforce and synergistic business environment. This property is well suited for aerospace and defense users, life science users, biotechnology users, and manufacturing users. HIGHLIGHTS • Flexible manufacturing spaces adaptable to various high tech processes. • Robust power infrastructure to support heavy machinery and sensitive equipment. • Employee amenities such as the cafeteria and charming grounds featuring numerous trees and ponds. • Ample parking. • Privately gated campus. Main Facility - 204,542± Sq. Ft. (YOC 1991) ATS Building - 8,964± Sq. Ft. (YOC 2013) Garden Building - 5,460± Sq. Ft. (YOC 1992) Garden Shed - 2,400± Sq. Ft. (YOC 1992) Total - 221,366± Sq. Ft.

Property Type:

Industrial

Date on Market:

2024-09-20

Centennial Retail, Flex for Lease

Strong ownership with recently completed property upgrades including new exterior paint, new roofs, new HVAC, and parking lot resurfacing.

Date on Market:

2026-05-04

Watkins Industrial for Lease - Outlying Arapahoe County

3MW power available now and potential to add 700MW more Campus building and 800 Acrage with secured gate access for lease, heavy industrial zoning allows variety of usages- 30 min Denver International Airport and 10 min from Aurora, CO.250,000 gallons private water tank 50-60 million gallons more available each year

Property Type:

Office

Date on Market:

2024-07-26

Louisville Flex for Lease - Boulder County

– Building Boasts Plentiful Windows & Natural Light Throughout, Showers, Elevator, & Shared Shipping & Receiving Area with Loading Dock – Convenient to Boulder & Denver with Abundant Parking (3.56:1,000), Bike Path Access & New RTD Service Coming Soon

Date on Market:

2026-01-15

Aurora Office for Lease

This recently renovated office building is located in a great SE Aurora location. The building features an updated lobby, updated units, and abundant free parking. A responsive local landlord. Current spaces available include heavy power lab space, open floorplans and traditional office. This building is within walking distance of the RTD 9-Mile Light Rail & Bus Station. Proximity to Parker Rd. & I-225 assures easy access, with numerous retail and restaurant amenities nearby.

Date on Market:

2026-03-11

Loveland Office, Industrial for Lease - Fort Collins/Loveland

• Office Space: Exquisite office environment within the Loveland Tech Center, offering exceptional amenities and a professional atmosphere. • Endless Parking: Enjoy ample parking space for employees and visitors. • Elevator Access • Sprinkler System • Abundant Natural Light: Large windows allow for plenty of natural light. • Great Power: Benefit from great power capacity, catering to various office and lab needs. 200-800 Amps; 3-phase 2,594 - 8,191 SF $16.95 / SF / NNN $7.68 / RSF (Est. 2024) Flexible • Lab Space Potential: Explore the potential to convert the space into a lab, adding versatility to the property. • Prime Exposure: Enjoy prime exposure along Route 287, with building signage available to long-term tenants. • Convenient Location: Situated conveniently for commuters from Fort Collins, Loveland, and Boulder County, making it easily accessible to a broad talent pool. • Professional and Attentive Property Management • New Ownership

Date on Market:

2026-06-03

Boulder Office, Flex for Lease

Date on Market:

2024-04-09

Grand Junction Industrial for Lease

Grand Mesa Industrial Park is a campus offering multiple space configurations ranging from 4,000 SF to 115,000 SF. Campus includes 5 industrial buildings. Industrial amenities include multiple bridge cranes, 3 ton and 10 ton, floor drains, large 20' x 24' overhead doors, ceiling height - 26', power - 3 phase, enclosed truck wash, truck lube, chemical storage, and large fenced, secured yard. A stand-alone two story office building is located at the north entry. The property is located within an Enterprise Zone and also in the Opportunity Zone which offer various tax credit incentives. The industrial park is located on the southeast edge of Grand Junction, CO just 2.5 miles south of I-70, the region`s main east-west connector. US Hwy. 50 is 3 miles to the south.

Date on Market:

2025-10-16