20 Life Science Properties for Lease in Missouri, USA

Hazelwood Office for Lease - Airport

Located in the highly active and business-friendly area of Hazelwood, Missouri, and adjacent to the St. Louis International Airport, the professional office property at 945-951 Hornet Drive offers an exceptional environment for companies seeking visibility, convenience, and a strong sense of community. Situated directly across from the Boeing campus, tenants will enjoy being part of a thriving corporate neighborhood. The property provides ample on-site parking, a high standard of professionalism, and a strong sense of safety, making it ideal for businesses that prioritize both functionality and prestige. The available move-in-ready spaces include flexible space options ranging from 1,200 to 3,500 square feet, ideal for growing teams as well as institutional tenants. Just minutes from St. Louis Lambert International Airport, the location offers seamless access to major transportation routes, with Interstate 270 directly adjacent, and both Interstates 70 and 170 only minutes away. This well-connected location sits just 3.9 miles from SSM Health DePaul Hospital, offering added strength for medical tenants. The area is also an established commercial hub, providing employees with easy access to exceptional conveniences, including retail, restaurants, and service-based amenities. 945-951 Hornet Drive poses an excellent opportunity for companies looking to establish or expand their presence in one of the most accessible and well-regarded business corridors in the St. Louis metro area.

Date on Market:

2026-04-08

Saint Louis Flex for Lease - I-270/Maryland Heights

Date on Market:

2026-03-24

Saint Louis Flex for Lease - St Louis City

Date on Market:

2026-02-02

Saint Louis Office for Lease - St Louis City

Date on Market:

2025-11-24

Creve Coeur Office for Lease - Creve Coeur/Hwy-67

Date on Market:

2025-06-11

Bridgeton Office for Lease - Airport

Date on Market:

2025-04-15

Kansas City Office for Lease - Ward Parkway

Date on Market:

2024-04-11

Fenton Flex, Industrial for Lease

The Cassens Industrial Park, located within the Fenton Interstate Industrial Center, is a mixed-use office and light-industrial building complex located at the southern intersection of Cassens Court and Cassens Drive in Fenton, Missouri. The 19.84-acre site is improved with four single-story commercial buildings, labeled as Buildings A-D. Two of the buildings, Buildings B and C, are conjoined, and all four buildings are slab-on-grade construction. All of the buildings feature the dedication of on-site ownership and property management, ample parking, and ribbon-window lined offices. Individual buildings and suites can offer air-conditioned storage, automatic door openers for drive-in doors and loading docks, and there exists the option to reactivate existing dock doors to assist in further distribution options. Cassens Industrial Park is further improved with sidewalks, shared loading docks, asphalt-paved parking areas, and landscaping. This industrial park is strategically located in a mixed commercial and light industrial area in Fenton, and benefits from proximity to the northwest corner of the I-270 and I-44 interchange. Located just five minutes from the Cassens Industrial Park, this interchange provides convenient commutes and easy distribution options. For further transportation and travel options, the St. Louis Lambert International Airport (STL), formerly Lambert-St. Louis International Airport, is a 36-minute drive away.

Date on Market:

2026-03-05

Saint Louis Office, Retail for Lease - St Louis City

316,000 SF - 8.5 levels. Construction underway - to be completed in 2024. Iconic tower in the heart of Cortex. Mixed-use office/lab/retail/restaurants. Surrounded by activated public spaces. Close proximity to the new Aloft Hotel and several restaurants. Structured parking (900+ spaces). Large flexible floor plates. Outdoor terraces and programmable spaces. Building signage opportunities. Restaurant and retail opportunities Lease Rate: $29.00 - $31.00/SF, NNN. Generous TI allowance: $80-$100/RSF

Date on Market:

2019-06-24

Creve Coeur Office/Medical for Lease - I-270/Olive Blvd

Office and Medical Office space available with views overlooking Creve Coeur Golf Course. Building includes abundant parking and is ideally located near I-270 and Olive Blvd.

Property Type:

Office

Date on Market:

2025-07-08

Saint Louis Office/Medical for Lease - Chesterfield/Hwy-40

Join the ranks of leading healthcare specialists and take advantage of superior visibility and connectivity with one of the high-end suites offered at 12855 N Forty Drive, the Walker Medical Building. 12855 N Forty Drive spans approximately 150,000 square feet across four stories and features a two-story parking garage, 24-hour access, ADA accessibility, and a backup generator for seamless operations and access. New tenants will be in good company with co-occupants in pediatrics, gastroenterology, neurosurgery, cardiology, family medicine, podiatry, general surgery, psychiatry, and more, a diverse mix to broaden referral networks. Walker Medical Building benefits from proximity to three major hospitals, Mercy (formerly St. John’s), Missouri Baptist, and St. Luke's, all of which are less than 10 minutes from the property. Local residents report a high payor mix and prioritize health and wellness with some of the most prestigious communities nearby, such as Town and Country, Chesterfield, Clarkson Valley, Ladue, and Des Peres. Connections to these patient pools are streamlined via direct access to Interstate 64 and other close arterial roadways. Many residents are organically drawn here, making this a convenient destination, with several local schools, colleges, country clubs, parks, and shopping districts moments away.

Property Type:

Office

Date on Market:

2026-04-29

Saint Louis Office for Lease - Creve Coeur/Hwy-67

Located in the heart of St. Louis’ 39 North District, 1001 N. Warson Road presents a premier opportunity for ag-tech, pharmaceutical, and life sciences users. This Class A facility features flexible office and laboratory space designed to support advanced research, innovation, and growth. Surrounded by industry leaders such as Bayer and Pfizer, the property offers tenants direct access to top-tier talent, cutting-edge resources, and a robust life sciences ecosystem within one of the region’s most established innovation corridors.

Date on Market:

2026-01-16

Blue Springs Medical for Lease - East Jackson County

This Class B, multi-tenant medical office property was constructed in 1993 and is zoned SO. Building features include signage, central heating, elevators, natural light and air conditioning.

Property Type:

Office

Date on Market:

2022-12-07

Saint Louis Office for Lease - St Louis City

Architecturally striking and built to Fortune 500 standards, 4300 Duncan is a future-forward workplace with technology and collaboration at its core. Infused with equal parts productivity and lifestyle, 4300 Duncan is situated at the center of the Cortex Innovation District; a gravitational hub for top global talent. Cortex is a vibrant, 200-acre hub of business, innovation, and technology integrated into St. Louis’ historic Central West End and Forest Park Southeast neighborhoods, surrounded by nationally-ranked universities and medical centers and abundant cultural and recreational assets. Cortex is a catalyst for innovation that brings together big-thinking problem solvers with state-of-the-art resources, facilities, and innovative programming to inspire and drive collaboration.

Date on Market:

2025-08-19

Saint Louis Office for Lease - St Louis City

@4240 offers a unique environment for a range of companies including those involved in life sciences, research, technology, legal, innovation and entrepreneurship. The building is conveniently located within the CORTEX Innovation District.

Date on Market:

2022-03-30

Saint Louis Office for Lease - St Louis City

- 38,797 SF Available - Located in the heart of Cortex - Surrounded by activated public spaces - Close proximity to the new Aloft Hotel, Cortex Commons, several restaurants, including Vicia, Park Avenue Café, and additional amenities - Adjacent surface parking - Building signage opportunities - Two building conference rooms - LEED Certified CS

Date on Market:

2021-05-18

Saint Louis Office for Lease - Creve Coeur/Hwy-67

BRDG PARK is a post-incubation, wet laboratory and office building in the heart of 39 North. It is one of three buildings in the ag tech research park. BRDG PARK is also known as the Bio-Research & Development Growth Park at the Danforth Center to support the needs of life science companies. In 2010, this building was awarded LEED certification at the Gold level by the U.S. Green Building Council. The Bio-Research & Development Growth (BRDG) Park is uniquely prepared and positioned to host plant and life-science and clean-tech companies. BRDG Park is designed for companies from early-stage to those that have advanced their science, demonstrated proof of concept, raised additional funds and are poised for growth. There are several leasing opportunities at BRDG Park Building. Wexford can customize wet labs, dry labs and office space to meet your specialized life science, plant science, ag tech or clean tech needs. BRDG Park provides generous tenant improvement allowances which can help many companies by eliminating upfront costs and preserving capital for core business activities. Located on Warson Road just north of Olive Blvd. in St. Louis County's Creve Coeur market between Interstate 270 and Interstate 170.

Date on Market:

2026-04-29

Columbia Office/Medical, Medical for Lease

Establish a presence in a market-leading health care campus with a space at Broadway Medical Plaza 4. This three-story medical office building (MOB) is situated on the Boone Medical Center campus with connections throughout, including to Boone Hospital, via a covered skywalk system. The available suites are well-sized for growing practices, with contiguous options available for larger footprints. Visitors and staff enjoy ample parking, including a garage that is connected to the skywalks. Due to this cohesive design, tenants of Broadway Medical Plaza 4 can leverage a vast referral network and utilize the hospital’s medical infrastructure, such as the emergency room and surgery center. Located at 1750 E Broadway, the MOB is on Columbia’s primary east-west thoroughfare, providing a direct shot to downtown in less than a mile. In addition to the rich professional scene on campus, practices can collaborate with the University of Missouri and its hospital within a five-minute drive. The area is convenient for staff and patients alike, with local favorites proliferating Downtown Columbia, while dozens of essential stores and national restaurant brands are a mile east down Broadway. Commuters and guests coming from outside the city center also enjoy seamless access with Interstate 70 and Highway 63 five minutes away. Remedy Medical Properties is a leading owner and operator of outpatient medical real estate, delivering integrated services across investments, development, leasing, management, and strategy. We own and operate medical office properties so healthcare providers can focus on patient care. Remedy specializes in the leasing of medical office space and outpatient medical buildings for physicians, health systems, and medical groups nationwide. Our team works directly with providers to deliver flexible space solutions that support clinical operations, patient access, and long-term growth. Learn more at remedymed.com

Date on Market:

2026-02-25

Fenton Office/Medical for Lease

St. Francis Medical Office Building in Fenton, MO, offers an exceptional location directly on the SSM St. Clare Hospital Campus. This prime medical office building is directly attached to SSM Saint Clare Health Center, ensuring convenience for both medical professionals and patients. With ample free surface parking and a synergistic tenant specialty mix that includes two large multi-specialty and internal medicine groups, this property provides excellent referral opportunities. Additionally, competitive lease rates and generous tenant improvement allowances make it an attractive choice for healthcare practices looking for a modern and customizable space.

Property Type:

Office

Date on Market:

2020-04-03

Maryland Heights Flex for Lease - I-270/Maryland Heights

Worthington Access Drive is a masonry and concrete block building constructed in 1974, located in the Maryland Heights submarket. The property lies within proximity to Westport Plaza and major highway networks including Interstate 270 and Highway 364. It is situated in an “M-1” Light Manufacturing District with supporting amenities such as dining, entertainment, and retail nearby.

Date on Market:

2026-04-22