12 Life Science Properties for Lease in San Francisco, CA, USA

San Francisco Office for Lease - Mission Bay/China Basin

Think big and execute any business vision with room to grow within one of the two buildings at the China Basin. The landmark Wharfside Building was constructed by the Southern Pacific Railroad in 1922. The Berry Building was added in 1991 and supplemented in 2008 by a two-story add-on using a mid-structure base isolation system, a first in the United States. This campus has the longest floor plates in San Francisco and over 55,000 square feet of open space, more than any privately owned building in the city. A multi-level promenade with outdoor seating allows tenants to enjoy spectacular Bay views and provides a space to host truly memorable events for employees and clients. The newly designed courtyard features multiple outdoor living rooms and meeting areas, with comfortable seating, fire pits, and overhead heating elements. Situated on the San Francisco Bay and across the street from the San Francisco Giants’ ballpark, the China Basin campus is proudly owned by McCarthy Cook & Co. Tenants enjoy a stunning landscaped central courtyard that runs the entire 900-linear-feet block with an on-site café and bakery surrounded by covered seating. A multi-level wharf promenade flanks China Basin, providing tenants with outdoor lounge areas and views overlooking the Bay. Other on-site conveniences include a continuous weekday shuttle service to the Financial District and BART, shower facilities, and a bicycle storage room. Behind the scenes, a skilled management team backed by a complete engineering, janitorial, and security staff provides timely, tenant-oriented service and support. China Basin is a vibrant location at the Mission Bay gateway, benefitting from excellent highway access to heavily trafficked transit. Interstate 280 and Interstate 80 are less than a four-minute drive, and the San Francisco Station provides car-free commuters with access to the Caltrain in a three-minute walk. The China Basin neighborhood features a wide array of restaurants, numerous entertainment attractions, and a full list of retail and service establishments. China Basin makes it easy to work, live, and play within walking distance of the office.

Date on Market:

2025-10-23

San Francisco Industrial for Lease - Bayview/Hunters Point

1409 Egbert Ave is a modern, multi-tenant industrial facility located in San Francisco’s Bayview neighborhood, constructed in 2021 to support a wide range of light industrial and creative uses. The building features customizable space with soaring 18-foot ceilings, large industrial-grade windows that provide abundant natural light, and wide access points suitable for loading and vehicle maneuvering. Zoned PDR-1 and PDR-2, the property is equipped with robust infrastructure including 3-phase power (600 Amp), heavy-duty electrical systems, high-speed internet, and an ESFR sprinkler system for enhanced fire protection. Tenants benefit from 24/7 secure access, dedicated restrooms, a shared lobby entryway, and convenient street parking. Strategically positioned near I-280, US-101, and public transit, the location offers seamless connectivity to SOMA, downtown San Francisco, and the broader Bay Area business ecosystem.

Date on Market:

2025-10-17

Daly City Medical, Retail for Lease - Brisbane/Daly City

This +/- 14,731 sqft. former Blue Pearl 24-Hour Emergency Pet Hospital Surgery Center can be taken as a whole or is demisable into three separate and distinct spaces. Suite C +/-4,050 sqft of veterinarian surgical space, Suite E +/-9,531 sqft of veterinarian surgical space or general lab space, and Suite L +/-1 ,150 of general lab space. This entire space recently underwent a +$5M buildout and is possibly the finest and certainly the newest 24-hour pet care facility on the peninsula. This turn-key emergency veterinarian hospital will generate revenue from day-1 as all it needs is your finishing touches and your dedicated team. This well designed and carefully thought-out care facility is highly visible and easily accessible from both directions on Hwy. 280 and is ideally located in a service area gap for 24-hour emergency vet services. Ample parking, a strategic workflow design for in-take, exam, ex-ray, endoscopy, pre-op, surgery, post-op, and recovery rooms awaits the peninsula's newest 24-hour emergency pet hospital. Again, this entire space is demisable to fit your business needs.

Date on Market:

2025-10-08

San Francisco Multiple Space Uses for Lease - South Financial District

San Francisco Historic Landmark Fantastic SoMa location at 2nd St & Howard St Adjacent to LinkedIn HQ and Salesforce HQ Can be delivered 100% Plug & Play with custom furniture Four floors, including a finished lower level Retail & Gallery Ground Floor R&D Laboratory with CERS Certification Capacity for ~150 workstations 5 medium meeting rooms 2 large boardrooms 20 phone booths Exposed brick throughout 4,000sqft private parking lot Full kitchen and an additional half kitchen Security & keycard system in place Freight elevator Impossible to get historic blade signage opportunity Ideal layout for hosting events with off-street access

Date on Market:

2023-03-22

Daly City Flex for Lease - Brisbane/Daly City

GENESIS – Station is a nine-story Class A laboratory and office building with large, open floor plates ideal for modern lab design. Within walking distance to BART, GENESIS – Station offers superior access to employees who commute from the North, South, and East Bay, along with its strategic location between two of the largest California life science institutions, UCSF and Stanford University.

Date on Market:

2025-05-06

San Francisco Flex for Lease - Mission/Potrero

Centrally Located Next to Major Highways & MUNI Lines. Owned By Prologis, Largest Industrial Real Estate Company in the World. Building is Fully Sprinklered Most Units Have HVAC 15’ Clearance. Scalable 3-Phase Power On Site.

Date on Market:

2024-07-09

San Francisco Flex for Lease - Mission/Potrero

Date on Market:

2022-02-17

San Francisco Medical for Lease - West of Van Ness

Five-story medical office building in Pacific Heights on the Pacific Campus of California Pacific Medical Center at Webster and Clay Streets. Approx. 150 doctors representing a broad spectrum of specialties, such as internal medicine, orthopedics, ob/gyn. Class A energy efficient building with bipolar ionization air filtering system, new elevators, Class A high energy efficient building, clean and well cared for building, well-lit and freshly painted garage, large lobby featuring the work of local artists, concierge and security.

Property Type:

Office

Date on Market:

2025-01-06

San Francisco Office for Lease - Mission Bay/China Basin

Date on Market:

2025-07-29

San Francisco Retail for Lease - Van Ness/Chinatown

SPECTACULAR VAN NESS AVENUE FRONTAGE Commercial Ground Floor The NEW 1100 Van Ness Avenue Medical Office Building is now open and serves as a major support facility for the new California Pacific Medical Center across the street. Located at one of the most dynamic intersections in San Francisco, Van Ness Avenue (HWY 101) is one of the top 3 highest traveled major arterials in San Francisco. Geary Street runs from Downtown San Francisco through the Richmond District—all the way to the Pacific Ocean. Listing may not include certain utilities, building services and property expenses. Flagship Opportunity Corner Space High Ceilings Signage Avaialble Food Use Strongly Desired (No Hood) Entrance on Van Ness & From Interior Lobby Located Near Starbucks Tenant Improvement Dollars Available for Qualified Tenants Just steps away from City Hall, War Memorial Opera House, Davies Symphony Hall, Polk Street and the affluent Pacific Heights and Russian Hill neighborhoods.

Property Type:

Office

Date on Market:

2025-05-13

San Francisco Flex for Lease - Mission Bay/China Basin

Date on Market:

2025-12-03

San Francisco Flex for Lease - Mission Bay/China Basin

215,000 SF (Divisible by Floor) 7 floors Large efficient floorplates: 32,000 SF – 36,000 SF Designed by IwamotoScott Architecture Panoramic city views Class A lab-ready shell 3,350 Amp, 277/408V, 3-Phase Onsite generator Enhanced live load: Live load of 100 lbs/SF & Special design to minimize vibration Hazardous chemical storage available Adjacent to a future public park Ready for Tenant Improvements

Date on Market:

2022-07-11