10 Life Science Properties for Lease in San Mateo, CA, USA

Belmont Office for Lease - Belmont/San Carlos

The property sits on a hilltop site with scenic views of the Bay Area and provides monument signage for strong visibility. Outdoor amenities include a large patio space, while interior features include two restrooms, two showers, and multiple storage areas. With abundant parking at a ratio of 3.5/1,000 and proximity to major highways—just two minutes from Highways 280 and 92 and five minutes from Highway 101—this location ensures excellent regional connectivity. The building is equipped with 800 amps, 208 volts, 3-phase power, supporting advanced operational needs.

Date on Market:

2026-03-26

Foster City Flex for Lease - Foster City/Redwood Shrs

Flexible Term Length 1-5 years • Freestanding 31,320 SF building • Plug & Play Office and Lab setup • 24 BSC hoods, 4 chemical fume hoods • Most of the Lab equipment is staying in place (full list upon request) • Central lab air, vacuum, purified water • CO2, N2, O2, He gas lines piped from yard • Single-pass lab HVAC • Cold room & glasswash rooms (Steris washer/dryer) • 1,600 amps, 277/480V power • 2 backup generators (150kW each, both voltages) • 1 grade-level loading door • Security with card access control • 3.3/1000 parking ratio • Low NNN: ~$0.30/SF

Date on Market:

2025-06-25

San Mateo Office, Flex for Lease

68,706 Square feet of lab and office space. Located in a highly sought-after, highly visible San Mateo location. The flex, lab and office building is owned by Rubicon Point Partners. The building was fully renovated with the 4th floor accommodating for co-working tenants and private labs. The tenants have access to an outdoor meeting and lounge area.

Date on Market:

2025-05-21

Redwood City Flex for Lease - Foster City/Redwood Shrs

Property Type:

Office

Date on Market:

2024-10-02

San Mateo Office, Flex for Lease

262,000 SF Class A life science campus located at 901 & 951 Mariners Island Boulevard. Immediate access to all major highways: 92, 101 and 280, ideal for employees commuting from anywhere in the Bay Area. Walking distance to Bridgepointe Shopping Center and direct access to the Bay Trail for running, walking, or biking. Access to Foster City Commuter shuttles with service to Hillsdale Caltrain and Millbrae BART.

Date on Market:

2023-10-17

San Mateo Office, Flex for Lease

GENESIS 1400 Fashion Island offers 200,000-square-feet of Class A life science research space in the heart of San Francisco’s Peninsula. Delivering the GENESIS spec program, the project provides small- to mid-size lab and office suites ranging from 10,000- to 25,000-square-feet. Floorplates vary in size offering a variety of single and multi-tenant options. The building underwent an extensive upgrade including all new MEP (mechanical, electrical, plumping) infrastructure, a new service elevator, and a backup generator to bring it to today’s lab industry standards. GENESIS fronts Highway 92 with immediate access to Highway 101, Interstate 280, and the San Mateo Bridge. The San Francisco International Airport is seven miles north of the project and the Mariners Island Caltrain Shuttle stop is across the street. The property features extensive landscaping with beautiful surrounding redwood trees, a central outdoor plaza with seating areas, and ample parking both at surface level and with a 3-level parking structure. EV charging stations will be provided for use. Located in the center of the peninsula, between Stanford and UCSF, this location offers unparalleled access to the world’s leading innovation clusters which enables growing companies to attract and retain talent from across the Bay Area’s research institutions. Come be a part of GENESIS - The Root of Innovation.

Date on Market:

2023-09-14

Redwood City Flex for Lease - Foster City/Redwood Shrs

Bayshore Technology Park. 3800 Bridge Parkway, Redwood Shores, CA.

Date on Market:

2026-03-09

San Mateo Flex for Lease

Genesis 1900 Alameda de las Pulgas offers ±113,000 SF of Class A life science research space. The proximity to Stanford and South San Francisco creates unparalleled access to the world’s leading innovation clusters. Located in the center of the peninsula, the project connects directly to San Jose, East Bay and San Francisco which enables growing companies to attract and retain talent from across the Bay Area’s research institutions (Stanford, UCSF, and Berkeley). The floor plates offer a variety of small to mid-size suites and solutions for life science companies.

Date on Market:

2025-11-06

Redwood City Office for Lease - Foster City/Redwood Shrs

Strategically located near Stanford University and other major educational institutions, 200 Twin Dolphin has direct access to the world’s most highly educated and sought-after talent. The location is immersed within influential technology and life science centers which have funded, produced, and retained the world’s most iconic high growth companies. The building’s prominent corner offers iconic visibility in Redwood Shores with a unique opportunity for building signage. The site is carefully designed to preserve the connection with the surroundings and offers a functional layout for a research or technology organization. Among world-renowned technology and life science centers, Redwood Shores is prime innovation real estate. The corporate neighbors are among the most competitive companies in the world and create an excellent environment for collaboration and new ideas. Local restaurants, shopping, fitness, hotels and other services are available within close proximity. There is also easy access to Downtown San Carlos and Downtown Redwood City.

Date on Market:

2020-06-03

San Mateo Flex for Lease

Date on Market:

2025-05-29