27 Life Science Properties for Lease in Tennessee, USA

Nashville Medical for Lease - West End

The Atrium is a four-story medical office building located on the Centennial Medical Center Campus. With its straightforward façade and abundant windows, natural light fills the property throughout the day. There are two available suites designed specifically for medical tenants, offering flexible layouts to suit changing needs. These spacious areas support comfortable floor plans and easy adaptability. The building is conveniently connected to the Centennial campus and includes amenities such as a cafeteria, valet service, both surface and garage parking, and on-site security and property management. Tenants enjoy a substantial Tenant Improvement Allowance and close proximity to multiple referring physicians on campus. 250 25th Avenue N is strategically located in Nashville, just west of downtown, with convenient access to major transportation routes that facilitate efficient travel to and from the property. The site is situated near several prominent medical buildings, enhancing connectivity within the area. TriStar Centennial Medical Center is a 741-bed hospital offering a wide range of medical and surgical specialties. Ascension Saint Thomas Hospital Midtown is also close by, offering a comprehensive facility with 24/7 emergency care, heart and vascular services, orthopedics, cancer care, maternal and fetal medicine, and breast health services. Vanderbilt University Medical Center stands as the largest healthcare institution in the Mid-South region, renowned for its research, teaching, and patient care services. Additionally, proximity to various retailers and essential services ensures a convenient and satisfying experience for tenants. Tenants also benefit from the vibrant atmosphere created by nearby dining venues, parks, and cultural attractions, making it an appealing destination for both work and leisure. The Atrium is a premier place for medical practitioners seeking a dynamic space in Nashville’s coveted medical district.

Property Type:

Office

Date on Market:

2026-01-19

Memphis Multiple Space Uses for Lease - East

Park Station invites growing businesses to claim premier medical and office space at the heart of East Memphis at 5180 Park Avenue. This contemporary facility spans a total of 38,553 square feet across three floors, with a variety of flexible floor plans that perfectly accommodate a wide range of commercial uses. Available spaces range from 862 to 2,600 square feet, with several contiguous options, allowing both growing businesses and institutional tenants to find the perfect space for their next phase of growth. All suites enjoy versatile layouts with private office/exam rooms, reception areas, and collaborative open spaces, and select units include lofts, lab space, break rooms, and private terraces. Units are available on the first and second floors, all with first-floor accessibility. There is ample parking available, and on-site management ensures a clean, secure, and business-ready environment. Park Station provides an attractive address for businesses, situated at the signalized intersection of Park Avenue and White Station Road. This high-traffic corridor offers great exposure for businesses, visible to more than 30,000 passing vehicles each day. The location ensures convenient access for staff and clients from across the greater region, sitting within minutes of the Interstate 240 interchange, Highway 285, and Interstates 40 and 55. Medical tenants will find themselves at home at Park Station, which sits only a short distance from several major hospitals. The location is just a short drive from St. Francis Hospital, Baptist Memorial Hospital, and St. Jude Children’s Research Hospital. These pillars of the local health care industry have drawn a large number of synergistic practices and medical offices to the area, laying the ground for lucrative partnerships and referrals for tenants of Park Station. The area surrounding Park Station presents an established retail hub, enhancing appeal with proximity to popular local shops and restaurants, as well as industry-leading retail brands like Whole Foods, Home Depot, Kroger, Gold’s Gym, Crunch Fitness, Pep Boys Auto Service, Dunkin’, McDonald’s, and more. The property is also just a short drive from the Wolfchase Mall, offering tenants access to over 115 upscale shopping and dining options across 1.1 million square feet. The seamless accessibility and robust amenities of this sought-after business destination come together to deliver an improved work-life balance for employees. Medical and professional office tenants at Park Station will be able to leverage fantastic workforce availability when considering future growth and expansion. When looking within just a 5-mile radius of the property, there is a dependable workforce of more than 146,000, with over 32% carrying a bachelor’s degree or higher, and more than 27% employed in education and health services fields. This valuable talent pool fuels an energizing and productive commercial setting that empowers businesses seeking to enter or expand in Tennessee’s second-largest city. Contact the Cohen Investment Realty team today to schedule a tour and find the perfect space.

Date on Market:

2024-10-04

Nashville Office/Medical for Lease - West End

1718 Charlotte Pike presents a versatile office and medical office leasing opportunity along one of Nashville’s primary commercial corridors. The property offers three suites across two floors with flexible layouts designed to accommodate healthcare providers, professional service firms, and administrative users seeking convenient access to Downtown Nashville. The building features existing medical office infrastructure, including reception areas, waiting rooms, exam rooms, private offices, lab spaces, and support areas that allow tenants to significantly reduce buildout costs and accelerate occupancy. First-floor suites provide direct access for patients and clients, while the second floor is served by elevator access, making the property suitable for a wide range of clinical and professional uses. Suites are available individually or can be combined for a full-building opportunity totaling approximately ±10,315 square feet, providing an ideal option for larger medical practices, outpatient services, behavioral health providers, or organizations seeking a centralized office location. Located along Charlotte Pike, the property benefits from excellent visibility and connectivity to Downtown Nashville, Midtown, West End, and surrounding residential neighborhoods. The area is supported by strong population growth, nearby retail and dining amenities, and convenient access to I-40, making it an attractive location for businesses serving both local residents and the broader Nashville market.

Property Type:

Office

Date on Market:

2026-03-10

Murfreesboro Industrial for Lease - Rutherford County

Exceptional opportunity to lease a 30,000 square foot commercial warehouse located in the heart of Murfreesboro’s established industrial corridor on Park Avenue. This well-maintained facility offers a functional layout designed to support a variety of industrial, manufacturing, research, or distribution users. The property features a strong mix of office, operational, and specialty workspace, including 9 private offices, 2 conference rooms, and a dedicated break room, providing ample space for administrative and team collaboration needs. In addition to the office component, the facility includes 3 laboratory spaces, a control room, a sample room, and a maintenance room, making it particularly well suited for manufacturing, testing, production, or technical operations. The warehouse portion offers significant square footage for production, storage, or logistics, while the office build-out allows businesses to operate efficiently with both management and operational teams under one roof.

Date on Market:

2026-03-04

Kodak Office, Retail for Lease

Rare opportunity to lease a fully built-out 6,000 SF medical office suite at 3609 Outdoor Sportsman Place, Kodak, TN (Suites 6, 7, 8 & 9), conveniently located just off I-40 for maximum visibility and patient access. The space includes 12 exam rooms, ample reception and waiting areas, dedicated lab space, and X-ray/imaging capability — everything needed to begin seeing patients without delay. With medical-grade plumbing, exam-room infrastructure, and a layout designed for efficient patient flow already in place, this turnkey suite lets you skip costly renovations and move forward quickly. Also available is a 1,500 SF office / retail space on the second floor but can be accessed directly from front parking lot at the front of property and not requiring stairs.

Date on Market:

2026-03-02

Chattanooga Office/Medical for Lease - Outlying Chattanooga

The Atrium is a fully redeveloped medical building with prominent tenants including: CHI Memorial CHI Memorial Convenient Care CHI Memorial Lab/X-Ray CHI Memorial National Home Care CHI Memorial Nuclear Medicine CHI Memorial Pediatric Diagnostic Associates CHI Memorial Primary Care Associates CHI Memorial Regional Sleep Center Center for Sports Medicine and Orthopedics Center for Sports Medicine and Orthopedics  -  Rehab Services Distefano Medical Spa Hayes Hand Center Mary Ellen Lochar Breast Center Memorial Health Services NovaMed Surgery Center Pediatric Eye Specialists Plastic Surgery Group StartFragment The Heart Institute Woolfson Eye Institute

Property Type:

Office

Date on Market:

2023-11-10

Knoxville Office/Medical for Lease - North/Broadway

Rare turn-key medical facility in high growth 4th & Gill area available for lease!! This is for 315 Gill Ave only. Currently operated as a medical clinic, this professional property includes 8–10 exam rooms, 3 designated X-ray rooms + dark room, and multiple administrative spaces, making it ideal for medical groups, specialty practices, urgent care, or dental and diagnostic operators seeking a ready-to-launch location. Strategically situated near downtown Knoxville and major hospitals, this building allows a new operator to begin seeing patients immediately with minimal updates. The well-maintained layout offers excellent flow for patient care, administrative efficiency, and staff convenience. Property Highlights: - Fully equipped clinical layout with 8–10 exam rooms (all plumbed with sinks) - Designated X-ray rooms and dark room - Large staff break room - Ample parking for staff and patients - Reception/waiting room with natural light and high ceilings - Lots and lots of storage/record retention spaces if needed for ones practice Other potential uses: traditional office, chiropractic care w/ xray, contrast therapy and wellness location, etc. Tenant to verify all pertinent information as this information is deemed reliable but not guaranteed.

Property Type:

Office

Date on Market:

2025-11-06

Clarksville Office/Medical for Lease - Montgomery County

Prominent single-story office building located on a quiet cul-de-sac. Several free unreserved covered parking for employees and clients. Four (4) restrooms. Building and monument signage available. Covered front entrance and driveway. Private exterior building entrances available. Large atrium with skylights. Large waiting area. On-site Property Manager. Parking around the entire building. Front and rear entrances. Great space for Biotech, Biosystems Engineers, Automation and Robotics developers, Biochemists and Biophysicists, Biomedical Engineers, Chemical Engineers, Computer and Information Research Scientists, Computer and Information Systems Managers, Data Scientists, Data Analytics, Database administrators, Electronics Engineers, Geographic Information Systems Researchers, Information Security Analysts, Materials Engineers, Materials Scientists, Geological Engineers, Petroleum Engineers, Physicists, Software Developers, Video Game Designer and Web Developers.

Property Type:

Office

Date on Market:

2023-05-15

Brentwood Office for Lease

The Brentwood Business Center is a locally-owned, single story brick building in Brentwood, TN. Suites have full height glass entrances and individual HVAC units. Walk up parking provides a 3.5/1,000 ratio. The Brentwood Business Center prime location in the popular Maryland Farms area of Brentwood provides excellent accessibility to I-65, Old Hickory Blvd and Franklin Road. The building has visibility from the interstate and is convenient to all major developments, and abundant restaurants and retail in Brentwood.

Date on Market:

2026-03-30

Nashville Office, Medical for Lease - West End

Date on Market:

2026-04-28

Cleveland Office/Medical for Lease - Downtown Cleveland

Property Type:

Office

Date on Market:

2026-05-05

Memphis Coworking for Lease - Midtown

TN, Memphis - Union Avenue Regus Memphis – Union Avenue places your business in a high-profile location with stunning high-rise views and a landmark identity thanks to the nation’s largest outdoor art display. Located near Downtown Memphis, Cooper-Young, and Overton Square, this center offers quick access to key business, medical, and cultural districts. Whether you are a start-up or an established business, this executive office location provides a visible, professional presence in a thriving city of over 200,000 people within a 5-mile radius. The center provides a flexible mix of private offices, coworking spaces, and meeting rooms designed to grow with your business. Enjoy modern layouts, fully equipped meeting rooms, and professional workspaces with excellent natural light and views. Benefit from a prestigious address, convenient commuting, and nearby restaurants and amenities that enhance productivity and impress clients. Memphis – Union Avenue is ideal for businesses seeking visibility, convenience, and a dynamic city setting.

Property Type:

Office

Date on Market:

2025-12-16

Memphis Multiple Space Uses for Lease - Midtown

Union Centre - Modern Office & Medical Space for Lease in Midtown Memphis Union Centre is a newly renovated office building offering medical office suites and executive offices for lease in Midtown Memphis. Located in the heart of the Memphis Medical District, Union Centre delivers unmatched convenience, flexibility, and visibility for professionals and healthcare providers. Property Highlights: - Connected via skybridge to Methodist University Hospital - Flexible floor plans from 97 SF executive suites to 40,000 SF contiguous office space - Medical offices available now - move-in ready with minimal or no tenant improvements required - Multiple leasing options including ground floor retail, upper-floor offices, and top-floor penthouse suites - Exclusive LED billboard advertising for tenants - premium exposure on busy Union Avenue - Executive Suites Floor - fully furnished private offices for 1, 2 & 3 professionals, with shared conference rooms, break rooms, and reception - Prime Midtown location - on Union Avenue near I-240, within the Bio-Med Zone, Central Gardens District, and HUB Zone - Surrounded by restaurants, banks, retail, and public transit, minutes from Downtown Memphis, Overton Square and Cooper-Young - 40,000 SF of ground-floor space, ideally suited for a data center. Why Lease at Union Centre? Union Centre combines modern amenities with prime Midtown accessibility. Whether you’re establishing a new medical practice, relocating your corporate office, or seeking flexible executive suites, Union Centre offers the ideal workspace for success. Now Leasing - Schedule a tour today and discover why Union Centre is the preferred destination for Memphis medical offices and executive suites.

Date on Market:

2026-04-07

Nashville Medical for Lease - West End

Welcome to Westview Medical Plaza, a 3-story medical office building located just off Charlotte Avenue on 25th Avenue North, within the Centennial Medical Center Campus. Positioned in the heart of Nashville’s hospital district, this prime location offers seamless access to healthcare services and unparalleled convenience for patients and providers alike. With close proximity to several referring physicians on campus, Westview Medical Plaza is an ideal setting for medical practices seeking connectivity and accessibility.

Property Type:

Office

Date on Market:

2025-09-30

Oak Ridge Land for Lease - Anderson County

Opportunities abound for any number of uses. The site is primed for a development to capture the geography of the lot and take advantage of the acreage. This site stands as the last privately owned site before reaching the East entrance/gate to Oak Ridge National Laboratory.

Property Subtype:

Industrial

Date on Market:

2026-02-17

Chattanooga Office/Medical for Lease - Outlying Chattanooga

Property Type:

Office

Date on Market:

2025-07-14

Brentwood Coworking for Lease

Fulfil your business ambitions in Brentwood, Tennessee Discover flexible office space that works around you in Brentwood, Tennessee. Conveniently located close to a prestigious and growing submarket of Nashville with plenty of businesses and amenities, it’s the ideal place to base your business. All roads lead to you with nearby Interstate-65 making your location easily accessible. You’ll be in good company surrounded by the largest industries including health care and social assistance, professional, scientific, and technical services, and finance and insurance. Ready to take flight and build your portfolio with overseas clients? Get your relationship off the ground straight away by driving 23km and greeting them at Nashville International Airport. Ensure to make a lasting impression from the get-go with modern offices at a premium address in Brentwood, Tennessee. Be inspired every day in this high-end building boasting incredible views and an updated interior. Whether you’re collaborating, pitching or working solo, our fully furnished coworking areas, quiet meeting rooms and private spaces with business-grade WiFi will always match your professionalism. When you need to treat guests to a comfortable overnight stay, simply check them into the hotel next door. After a productive day, reward yourself or your team at the local steakhouse, just a short walk from the office.

Property Type:

Office

Date on Market:

2025-01-23

Chattanooga Office/Medical for Lease - East

Mission Surgery Center at 2515 DeSales Avenue is the premier opportunity to establish a presence in Chattanooga’s primary healthcare destination. The two-story medical office building (MOB) sits on the CommonSpirit – Memorial Hospital campus, which features an emergency room, pharmacy, wound care, cardiac imaging, a sleep center, dining options, and the Rees Skillern Cancer Institute. With a comprehensive mix of additional specialties on campus, tenants can tap into endless referral opportunities. The first floor’s efficient layout comprises dozens of exam rooms, private offices, reception, a large waiting room, and private restrooms. The layout can accommodate a wide range of practices and services, such as specialty wellness, dental, primary care, physical therapy, dermatology, lab testing, general health clinics, neurology, and more. Situated in East Chattanooga, 2515 DeSales Avenue is perfectly positioned for easy downtown access and proximity to health-conscious suburbs. Recent demographic data also indicate growing patient pools with annual growth rates in the area far exceeding the national average. As the largest medical campus in Chattanooga, CommonSpirit – Memorial Hospital already attracts thousands of patients, underscoring the importance of a campus presence. Remedy Medical Properties is a leading owner and operator of outpatient medical real estate, delivering integrated services across investments, development, leasing, management, and strategy. We own and operate medical office properties so healthcare providers can focus on patient care. Remedy specializes in the leasing of medical office space and outpatient medical buildings for physicians, health systems, and medical groups nationwide. Our team works directly with providers to deliver flexible space solutions that support clinical operations, patient access, and long-term growth. Learn more at remedymed.com

Property Type:

Office

Date on Market:

2025-01-21

Nashville Medical for Lease - West End

Property Type:

Office

Date on Market:

2026-04-20

Cleveland Office, Industrial for Lease - Downtown Cleveland

Located in Cleveland, TN, this property features 16,845 SF of available Office & Lab space.

Date on Market:

2022-01-11

Cleveland Medical for Lease

Peerless Crossing Medical Center at 1060 Peerless Crossing NW in Cleveland, Tennessee, is a Class-A, two-story medical office building that balances high visibility with seamless access to the region’s top healthcare institutions. With direct routes to Keith Street, I-75, TN-60, and US-11, this MOB is a hub for providers seeking location, amenities, and convenience. Suite 102, is a fully built-out spec suite (available September 2025), is designed to support quick move-in with no downtime. Lillibridge Healthcare Services manages Peerless Crossing with 24/7 responsiveness and a web-based maintenance system that makes requests seamless and fast. Property features include: 210 dedicated surface parking spaces Updated common areas and modern lobby New monument signage for enhanced visibility A fully furnished, shared conference room Proximity to Bradley Medical Center- Vitruvian Healthcare, an acute care facility with 350 beds and comprehensive emergency care Existing tenants include Bradley Medical Center and Peerless Pediatrics, driving built-in referral opportunities Whether your practice is expanding or relocating, Peerless Crossing offers a rare mix of readiness, amenities, and support.

Property Type:

Office

Date on Market:

2020-06-02

Nashville Office/Medical, Medical for Lease - West End

The property is located on Church Street within a mile of I-40 and downtown Nashville. The building neighbors the St. Thomas Midtown Hospital and features an air-conditioned connector for convenient access. The space also features ample parking including free valet, and is within walking distance to numerous amenities including restaurants, hotels, banks and the post office.

Date on Market:

2026-02-10

Memphis Coworking for Lease - 385 Corridor

A prominent corner location sets off the three-story brick-faced Southwind Center to great effect. The building in southeast Memphis is positioned at the corner of Tournament Drive and Players Club Parkway and overlooks well-kept landscaped grounds near the golf course. Set in the heart of the Southwind business park, it's easy to access from the East I-385 Corridor, I-240 and Hwy 385, and 20 minutes from the airport. The lobby boasts polished stone floors, mahogany paneled walls and full-height reflective glass windows. The long-time presence of FedEx's corporate HQ in the area has led to Memphis being dubbed America's distribution center. Other business corporates include a tobacco giant and incorporation, electrical and finance companies. There are also many life science and logistics firms, and a high number of manufacturers, particularly in flextronics and steel. The center is near many business amenities and excellent transportation.Fiber: BellsouthSecurity: Card ActivatedLocated at the corner of Tournament Drive and Players Club Parkway.This building was awarded an Energy Star label in 2012 for its operating efficiency. Memphis Municipality

Property Type:

Office

Date on Market:

2012-01-30

Knoxville Coworking for Lease - Cedar Bluff/Walker Spgs

Downtown Knoxville's vibrant business district, coupled with the innovation hub at Oak Ridge National Laboratory, creates a thriving environment for companies. The proximity to McGhee Tyson Airport ensures seamless connectivity, while the University of Tennessee supplies a steady talent pipeline for technology and healthcare sectors. Regus offers coworking spaces and meeting rooms in Knoxville to support your business growth.

Property Type:

Office

Date on Market:

2012-09-13